Javad mahmudi
,
Abstracts, [Author]
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Genotyping of Escherichia coli strains isolated from hospitals sewage
Microbiology and Infectious DiseasesToday one of the most common problems in the health society is the way of treating multidrug resistant (MDR) organisms. ...Read more
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Overexpression of cancer stem cell protein, Piwil2, promotes the expression of anti-apoptotic and proliferative genes in the gastric cancer cell line MKN-45
Cancer; Prevention, Diagnosis and TreatmentPiwi-like RNA-mediated gene silencing 2 (Piwil2) is an oncogene that is highly expressed in different tumors including ...Read more
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Survey of various aspects in polycystic ovary syndrome (PCOS)- A review
Women and Reproductive HealthPolycystic ovary syndrome (PCOS) is a complex endocrine disorder affecting 5–10% of women of reproductive age. It has ...Read more
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Evaluation of magnesium & copper levels and antioxidant power in serum of women with endometriosis before and after administration of N-acetylcysteine
Women and Reproductive HealthEndometriosis is caused by the presence of ectopic endometrial stromal outside the endometrial cavity. The oxidative str...Read more
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Identification and Cloning of Plasposon Insertion Site in Four Mutants of Pseudomonas Gingeri Deficient in White Line Reaction
Microbiology and Infectious DiseasesAntibiotic resistance is an important concern in the world and also in Iran. Identifying new antimicrobial strategies to...Read more
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Cloning and expressing the chimeric peptide lactoferricin-lactoferampin camel in Lactococcus lactis for promising as a candidate for oral medication
Nutrition and HealthLactococcus lactis is known as probiotics due to its lack of harmful toxins. Because of its high growth potential and re...Read more
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Study of HER2 gene expression in AGS cell line after treatment of cells with Crocus sativus (Iranian Saffron) extract
Cancer; Prevention, Diagnosis and TreatmentThe study of HER-2 gene in cancers, especially gastric cancer, is of great importance. This gene, has been shown to inc...Read more
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Development of a chemiluminometric lateral flow biosensor for sensitive detection of Escherichia coli
Microbiology and Infectious DiseasesPaper based nucleic acid testing (NAT) has attracted significant interest in point of care diagnostic field. Lateral flo...Read more
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CRISPR/Cas9-mediated gene Knockout
Cancer; Prevention, Diagnosis and TreatmentGenome engineering is a novel and powerful tool for biotechnological applications. The development of the Clustered Regu...Read more
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Evaluation of Adenovirus in Pseudomonas aeruginosa susceptible keratitis by PCR molecular method
Microbiology and Infectious DiseasesKeratitis is inflammation of the cornea of the eye. In keratitis, microbial agents are important. In the presence of inf...Read more
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Frequency and Pattern of Resistance of AmpC-Beta-lactamase gene in Clinical isolates of Klebsiella pneumoniae from Zahedan Educational Hospitals
Microbiology and Infectious DiseasesThe detection of CTX-M-15 genes in ESBLs produced by Klebsiella pneumoniae strains provides useful information on epidem...Read more
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Down regulation of Bcl2 and up regulation of Bax during 2-NDC mediated apoptosis in Acute Promyelocytic Leukemia NB4 cells
Cancer; Prevention, Diagnosis and TreatmentDithiocarbamates have been known as important chemical synthetic compounds for treatment of cancer....Read more
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Frequency of TEM and SHV genes in the strains of Acinetobacter producing broad-spectrum isolated ß-lactamases from Zahedan patients by PCR method
Microbiology and Infectious DiseasesAcinetobacter baumannii is one of the most important factors in hospital infections, and its Colonization rate in hospit...Read more
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A Turn-Off Fluorescent Sensor Based On Carbon Dots for Sensitive Detection of Tetracycline in Milk
Nutrition and HealthThe detection of tetracycline in animal-derived food and drug is very significant, because of its harmful effects on hum...Read more
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Cancer Stem Cell Therapy Based on Nanostructure Drug Vehicle, PMBN-IL3-GA
Nano-Biotech MedicalTo overcome difficulty of cancer treatment by conventional chemotherapy methods, the targeting drug delivery based on Na...Read more
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Effect of EMF on Semen TBARS Concentration
Women and Reproductive HealthElectrical instruments in human life by development of applications causes new biological phenomenon in this century. Ne...Read more
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Isolation and of merkel cell polyomavirus(MCV) in patient with skin cancer
Cancer; Prevention, Diagnosis and TreatmentSkin cancer is the most common malignancy in the world, with high disability and mortality is relatively low (Except for...Read more
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Constructing a Novel Hypoxia-Inducible Bidirectional shRNA Expression Vector for Simultaneous Genes Silencing in Colorectal Cancer Gene Therapy
Cancer; Prevention, Diagnosis and TreatmentBackground: RNA interference (RNAi) is an efficient genetic approach in gene-specific knockdown and gene therapy; howeve...Read more
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Treatment of vitamin D deficiency in pregnancy
Women and Reproductive HealthThe purpose of this study is the importance of Vitamin D in pregnancy and its treatment. Serum levels of Vitamin D in th...Read more
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Molecular markers in the diagnosis of lung cancer
Cancer; Prevention, Diagnosis and Treatmentlung cancer is the leading cause of cancer-related mortality, one of the main causes of mortality by 2010. There are sev...Read more
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Evaluation and comparison of digestion in two traditional and contemporary medicine schools And its effect on the treatment of diseases
Nutrition and HealthIn traditional medicine, one of the three most important nutritional principles is digestion. In our digestion, we deal ...Read more
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Using case–control study to find a relationship between SLC11A1 gene and clinical mastitis
Medical GeneticsMastitis is a major source of economic loss in dairy herds. The objective of this research was to evaluate the associati...Read more
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Cell-Penetrating Peptides and Tumor Targeting Peptides: achievements and challenges in application for cancer treatment
Cancer; Prevention, Diagnosis and TreatmentDespite significant advancement in the anti-cancer drugs recently, cancer still remains one of the leading causes of dea...Read more
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Some candidate Biomaterials for Amniotic Membranes (AM) Regeneration: a review
Stem cell and Medical ApplicationsAmniotic Membranes (AM) wich form the amniotic sac filled by amniotic fluid and completely surrounds the embryo/fetus. I...Read more
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Interaction of an anti-cancer drug Crizotinib with serum albumin: A docking study
Cancer; Prevention, Diagnosis and TreatmentCancer treatment is one of the major challenges of medical science today. Among them, lung cancer is a common type of ca...Read more
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Finding a new approach for Treatment of osteoporosis with trace element and antioxidant in rat animal model
Metabolism and Metabolic DiseasesOne of the most common bone metabolic and endocrinal disorders is osteoporosis. It is defined by progressive bone loss, ...Read more
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Study of DNA methylation pattern in sf-1 gene promoter region in endometriosis tissue samples of women in north west of Iran
Medical GeneticsEndometriosis is an estrogen-dependent inflammatory disease. Its defining feature is the presence of endometrium-like ti...Read more
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SNP genotyping within INS, INSR, TCF7L2 and PPR- y genes associated with type 2 diabetes in India
Medical GeneticsA pilot population-based study was carried out to evaluate linkage between singlenucleotide polymorphisms within the kn...Read more
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Cytotoxic activity of Berberine on the growth of breast cancer cell line (MCF-7)
Cancer; Prevention, Diagnosis and TreatmentMuch research has been conducted on the benefits of various phytochemicals in many herbs, fruits and vegetables and thei...Read more
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β-Cyclodextrin Modified Graphene Oxide Bionanocomposite for pH-sensitive Release of Anti-cancer Drug
Nano-Biotech MedicalGraphene is a multifunctional carbon nanomaterial and could be utilized to develop platform technologies for cancer ther...Read more
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Characterization of a carboxypeptidase inhibitor peptide isolated from Iranian scorpion venom glands cDNA library: a good candidate for cancer therapy
Cancer; Prevention, Diagnosis and TreatmentFinding a safe strategy for targeting tumor cells without affecting normal cells is one of the goals of cancer treatment...Read more
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An investigation on the structure and function of the cell surface breast-specific antigens for development a new generation of immunotoxins
Cancer; Prevention, Diagnosis and TreatmentBreast cancer with heterogeneous features in morphology, clinic, and responses to therapeutic options, is one of the mos...Read more
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CRISPR/Cas9-mediated designing of lung adenocarcinoma mouse model by method of knock-in
Medical GeneticsMolecular genetic studies in cell and animal models have evolved our knowledge of discovering causal mechanisms relating...Read more
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The role of artificial intelligence in medical decisions
Nano-Biotech MedicalThe term "artificial intelligence" was used in 1956. There is still no definitive definition of artificial intelligence ...Read more
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Managing The Abnormal Papsmear In Pregnancy
Cancer; Prevention, Diagnosis and TreatmentCervical cancer is the most common malignancy diagnosed during pregnancy . The incidence of abnormal pap smear in pregna...Read more
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Lack of association between TNF-α rs1800629 polymorphism and Hepatocellular Carcinoma: a meta-analysis
Medical GeneticsTumor necrosis factor a (TNF-α) is a pleiotropic cytokine which can regulate a wide variety of cellular responses. Low ...Read more
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Gene expression profiling of the 8q22-24 position in human breast cancer: TSPYL5, MTDH, ATAD2 and CCNE2 genes are implicated in oncogenesis, while WISP1 and EXT1 genes may predict a risk of metastasis
Cancer; Prevention, Diagnosis and TreatmentGene expression profiling has been suggested to predict breast cancer outcome. The prognostic value of the 8q22 24 posit...Read more
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study of microbial quality of some food samples
Nutrition and Healthbacterias are considered as the most important factor to cause infection and food poisoning ,so that microbial contamina...Read more
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The effect of ziziphora extract on the expression of the Claudin_1 gene in the AGS cell line
Cancer; Prevention, Diagnosis and TreatmentClaudins are the main structural and functional proteins of tight junctions in epithelial cells. The altered expression ...Read more
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Effect of vitamin E on liver index enzymes in normal and CCl4-intoxified male Wistar rats
Nutrition and HealthVitamin E is the key lipid-soluble antioxidants in humans. Vitamin E supplementation was effective in decreasing markers...Read more
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Determining the Interactions between Major Dietary Patterns and LRP5 Genotypes (rs556442) on Bone Discordance in Postmenopausal Women Referred to Shariati Hospital
Nutrition and HealthOne of the challenges in the diagnosis of osteoporosis is bone discordance. Many studies have confirmed an association ...Read more
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An investigation on the structure and function of the cell surface lung-specific antigens for development a new generation of immunotoxins
Cancer; Prevention, Diagnosis and TreatmentLung cancer, with common symptoms such as coughing, weight loss and shortness of breath, is a disease via uncontrolled g...Read more
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Induction of apoptosis by silibinin in SKBR3 breast cancer cell line through activation of caspase 3/7
Cancer; Prevention, Diagnosis and TreatmentThe poor prognosis of breast cancer is due to its resistance to the conventional treatments. Therefore, researchers are ...Read more
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Comparison of antimicrobial activity of hydroalcoholic extract of fig(Ficus carica) against Staphylococcus aureus(MSSA & MRSA) with some antibacterial drugs
Microbiology and Infectious DiseasesStaphylococcus aureus is one of the five most common causes of hospital infections and death the worldwide. The excessiv...Read more
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A Comparison of the efficacy of Fluconazole-loaded PLGA Nanospheres and Fluconazole on attachment of Candida albicans to hela cell
Microbiology and Infectious DiseasesThe human pathogenic fungus Candida albicans is commonly found on mucosal surfaces, such as the vagina. It has been wide...Read more
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Improvement of Prognostic model for breast cancer recurrence by data mining methods
Cancer; Prevention, Diagnosis and TreatmentIn Iran, every year 10,000 people suffer from breast cancer, of which half of them are under the age of 50. The recurren...Read more
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Alterations of gyrA in Enterobacteriaceae isolated of urinary tract infection resistance to quinolones antibiotics
Microbiology and Infectious DiseasesUrinary tract infection is one of the most common infections, which if not treated, it can be cause seriouse problem in ...Read more
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Anti-anxiety effects of sinapic acid in NMRI mice
Nutrition and HealthThe present study investigated the anxiolytic effects of sinapic acid on NMRI mice behavior in the elevated plus-maze (E...Read more
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Evaluation of antioxidant activity and cytotoxicity of an ethanol extract of leaves, fruits and calyx of Physalis alkekengi on human lung cancer A549 cell line
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the most common cancers and chemotherapy cancer treatment is one of the methods, but because of the lack ...Read more
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Genetic variations of Cholesteryl ester transfer protein and diet interactions in relation to lipid profiles and coronary heart disease: A systematic review
Nutrition and HealthThe number of investigations on diet–genotype interactions in the prevention or treatment of dyslipidemia have increas...Read more
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Investigating the role of exon7 axin2 in colorectal cancer (Laboratory and bioinformatics studies)
Cancer; Prevention, Diagnosis and TreatmentIn Iran, colon cancer is the third most common cancer. WNT pathway changes are commonly reported in this cancer. Among t...Read more
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Molecular study of 92 fetal of couples with recurrent abortion in Mazandaran
Medical GeneticsChromosome abnormalities has recognized as a major factor contributing to pregnancy loss and accounted for about 50% of ...Read more
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Evaluation of cytotoxicity, viability and induced oxidative stress by Nickel (II) complex of thiosemicarbazone
Cancer; Prevention, Diagnosis and TreatmentThiosemicarbazones and their metal complexes have significant biological activities including anticancer, antibacterial,...Read more
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Evaluation of TCA cycle in patients with acute myeloid leukemia
Cancer; Prevention, Diagnosis and TreatmentAcute myeloid leukemia (AML) is the most type of acute leukemia in adults. In solid tumors, alteration of energy metabol...Read more
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The effect of Rosa canina extract on Bax gene expression in gastric adenocarcinoma cell line(AGS)
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is the most common cancer in the world. It occurs as a result of many factor and there is massive invest...Read more
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The Study of the Requested Antibiotics during Each Patient’s confining to Bed in Namazi 1000 beds hospital, May 22nd to July 21st
Microbiology and Infectious DiseasesOccurring resistive microbial trends is one of basic obstacles in infection disease treatments. Prescribing too much ant...Read more
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Association between Biochemical Markers BHCG in Screening First Trimester of Pregnancy in Women with PCOS
Women and Reproductive HealthPCOS (polycystic ovary syndrome) is a common endocrine system disease among women of reproductive age. Its prevalence in...Read more
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Structural Study of Lysozyme upon Interaction with Plasmonic gold Nanoparticles
Nano-Biotech MedicalRecent advances in nanotechnology have encouraged scientists to design hybrid systems of nanoparticles and biological ma...Read more
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Effect of letrozole as alternative aromatase inhibitor on development of ovarian follicles and uterine changes in adult NMRI mice strain and their infants
Microbiology and Infectious DiseasesLetrozole is used as an aromatase inhibitor, to increase ovulation induction. This drug is usually prescribed for patien...Read more
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A review: Runt-related transcription factor 2 (RUNX2) and its signaling pathways in cardiovascular complications.
Metabolism and Metabolic DiseasesVascular calcification (VC) is a process similar to bone mineralization. VC has been observed in chronic kidney disease,...Read more
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Berberine induced apoptosis of HT-29 cells through mediating of miR-21
Cancer; Prevention, Diagnosis and TreatmentBerberine is an isoquinoline that can be extracted from many medicinal herbs. microRNAs (miRNAs) are small non-coding RN...Read more
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The effect of celastrol on gene expression of TNF-α (Tumor necrosis factor-a) induced by Influenza A virus (PR8/H1N1) in MDCK cells
Microbiology and Infectious DiseasesInfluenza A virus (IAV) can cause acute respiratory distress syndrome, which leading to kill 250000 to 500000 of world ...Read more
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Molecular mechanism of alpha-2 adrenergic receptors in locus Coeruleus
Medical GeneticsPain is one of the most common forms of psychological stress and the most common phenomenon in medical science. Analgesi...Read more
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The nutritional benefits of Pistacia atlantica
Nutrition and HealthPistacia Atlantica Mutica is a genus of the family Anacardiaceae which consist of different parts such as fruit, leave a...Read more
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Effect of hydroalcoholic leaf extract of Ziziphora tenuior L. on pain in male rats
Microbiology and Infectious DiseasesZiziphora tenuior is one of the traditional medicinal herbs; the main active chemical composition of this herb is an ing...Read more
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Shedding light on new form of combination therapy in acute promyelocyte leukemia
Cancer; Prevention, Diagnosis and TreatmentAlthough physicians have taken a variety approaches for the treatment of acute promyelocytic leukemia (APL), there is no...Read more
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Familial occurrence of Mayer-Rokitansky-Küster-Hauser syndrome in two siblings in Iran
Medical GeneticsFamilial occurrence of Mayer-Rokitansky-Küster-Hauser syndrome in two siblings in Iran Asadi fatemeh 1*, shokouholsa...Read more
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Evaluation of Adiponectin Hormone in Diabetic and Non-diabetic Patients
Metabolism and Metabolic DiseasesAdipose tissue is currently considered as a hormonally active system in the control of metabolism and not only as a stor...Read more
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The influence of lactobacillus fermentum cytoplasmic extract, isolated from traditional cheese (kuzeh) on the expression of p53 gen in K562 cancerous array via a quantitative Real time PCR method
Cancer; Prevention, Diagnosis and Treatmentthe probiotics are able to induce apoptosis in cancerous cells. chronic myelocytic leukemia (cancerous array of K562) is...Read more
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The Anticancer Effect of Plant Aqueous Extracts of Aloe Vera in Gene Expression Bax and Bcl-2 on Gastric Adenocarcinoma AGS Cells
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is a major cause of cancer death. In terms of incidence is the fourth most common cancer and the second l...Read more
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The effect of Bioactive glass on Adipose-derived MSC osteogenesis in 3D cultures
Stem cell and Medical ApplicationsRegenerative medicine is an emerging field of biotechnology that combines various aspects of medicine, cell and molecula...Read more
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Electrospun PVA/PVP/chitosan Membrane with Controlled Release of Antibiotics for intraperiodontal pocket drug delivery
Nano-Biotech MedicalGingivitis and periodontitis have become major public health problem in the world. Such growing incidence of periodontit...Read more
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The impact of miR-16 and miR-34a overexpression on the migratory and invasive potential of breast cancer cells
Cancer; Prevention, Diagnosis and TreatmentBreast cancer (BC) is the most frequent type of cancer and a main cause of cancer-related deaths among women worldwide. ...Read more
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Comprehensive databank of Iranian patients with Noonan syndrome
Medical GeneticsNoonan syndrome (NS) (OMIM 163950) considered as a relatively common (1/1000-2500), developmental, multi-organ and compl...Read more
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Discrimination of Leishmania species by Arginine permease gene AAP3as a suitable molecular tool for detection and genetic proximity analysis
Microbiology and Infectious DiseasesLeishmaniasis presents itself in different clinical manifestations such as: visceral Leishmaniasis, Cutaneous Leishmania...Read more
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Study the expression rate of claudin-1 gene in Crocus sativus (saffron ) treated AGS cell lines
Cancer; Prevention, Diagnosis and TreatmentClaudins are the main structural and functional proteins of tight junctions in epithelial cells. The altered expression...Read more
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Association Chlamydia trachomatis infection and TNFα -308 polymorphism in abortion
Microbiology and Infectious DiseasesSeveral bacterial infections such as Chlamydia trachomatis and host genetic background, including TNFα SNP polymorphism...Read more
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The role of natural antioxidants in treatment of cancer
Cancer; Prevention, Diagnosis and TreatmentCancer is one of the most common causes of death in advanced industrial societies. With the prevalence and spread of can...Read more
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The Approaches for Salivary Glands (SGs) Regeneration: a review
Stem cell and Medical ApplicationsSaliva is secreted from three pairs of major SGs and 100–800 minor SGs and plays a vital role in oral and general heal...Read more
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Investigating the effects of saffron and melatonin with radiotherapy on viability of Hela cells
Cancer; Prevention, Diagnosis and TreatmentNowadays, a lot of people in the worldwide dead because of cancer. Despite much research in this area, there is still no...Read more
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Frequency of TET Resistance Gene and TEM Beta-Lactamase Resistance Genes in the Normal Flora of the Intestines of Addicted People Without symptoms of Intestinal Infection and Diarrhea, IRAN-Ahvaz City
Microbiology and Infectious DiseasesWide studies in National Institute for Drug Abuse(USA) are done with preventive goals, or risk and protective factors as...Read more
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Effect of Velcade in Combination with Nanocurcumin in Breast Cancer 4T1
Nano-Biotech Medical: It is well known that breast cancer has the highest incidence rates of about 30% of all types of cancer in women, and ...Read more
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Comparative investingation of effects of the agricultural pesticides (diazinon and chlorpyrifos) on spermatogenesis in male BALB/c male mice
Nutrition and HealthDiazinon and chlorpyrifos are kind of organophosphate toxins used for agricultural pests. These toxins control acetylch...Read more
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Aloe Vera Herbal Effects on Diabetes Treatment and Prevention: A Systematic Review
Metabolism and Metabolic DiseasesDiabetes is one of the most common metabolic diseases that affects more than 150 million people in the world. It is the ...Read more
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Anticancer Application of Camel Milk: A Review of Recent Research
Cancer; Prevention, Diagnosis and TreatmentBecause of importance of cancer and the side effects of existing therapies, it is essential to find new therapeutic stra...Read more
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Client's Attitude Towards legal and Ethical Aspects of Sperm Donation in a Health Center of Tehran
Women and Reproductive HealthSperm donation is one of the technologies associated with infertility treatment. Some couples don't have any child due t...Read more
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Cucurbitacin D from Ecballium elaterium (L.) A. Rich upregulates BCL-2 gene in human gastric cancer cell line AGS
Cancer; Prevention, Diagnosis and TreatmentMedicinal plants are potential sources of new drugs and natural therapies based on them are becoming increasingly import...Read more
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Knowledge and Practice of Breast Self-Examination Among Female Students in Sari Islamic Azad University in 2015-2016
Cancer; Prevention, Diagnosis and TreatmentBreast self-examination (BSE) is one of the ways of prevention and early detection of breast cancer. The aim of this stu...Read more
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Wound healing effect of Tea tree oil on Methicillin Resistant Staphylococcus aureus (MRSA) : an Animal Study
Microbiology and Infectious DiseasesTea tree oil (TTO), or melaleuca oil, is an essential oil with a fresh camphoraceous odor and a color that ranges from p...Read more
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Investigating th expression of E-cadherin gen among patients suffering from stomach cancer in West Azerbaijan province
Medical GeneticsGastritis Cancer is one of the general death causes of cancer all over the world. According to the results of the resea...Read more
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Interaction of rs783540 of CPEB1 gene in patients with azoospermia
Medical Genetics: Publicly, 90% of fertile couples get pregnant in one year. Therefore, infertility refers to disability in pregnancy, a...Read more
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Optimization of epi-drug combination against Glioblastoma multiform cell line (U251) using Response Surface Methodology
Cancer; Prevention, Diagnosis and TreatmentGlioblastoma multiform (GBM) is the most common and aggressive form of primary brain cancer and has a dismal prognosis, ...Read more
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Anticonvulsant, neuroprotective and behavioral effects of magnesium sulfate on pentylenetetrazol-induced seizures in male Wistar rats
Nutrition and HealthMagnesium (Mg2+) is the second most abundant divalent and ubiquitous intracellular cation in mammalian cells and an ess...Read more
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Recent study about Genetics of Human Obesity
Medical GeneticsObesity has become a global epidemic and contributes to the increasing burden of type 2 diabetes, cardiovascular disease...Read more
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Investigating the specificity of the specific lytic bacteriophage against Salmonella bacteria and its effect on the hep2 cell line
Microbiology and Infectious DiseasesResistance to antibiotic treatments is one of the increasing problems. Therefore, alternative methods to reduce antibiot...Read more
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Chimeric Antigen Receptors (CARs) as a powerful approach for cancer therapeutics
Cancer; Prevention, Diagnosis and TreatmentT-cells have the potential to extirpate abnormal cells. The genetic modification and characterization of T-cells with ch...Read more
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Hepatoprotective effects of magnesium sulfate on pentylenetetrazol-induced seizures in male Wistar rats
Nutrition and HealthMagnesium is the second most abundant cation (after potassium) in the cell and plays an important role in various biolog...Read more
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Interference of Dopamine D2 Receptors and Food Restriction on Changing Anxiety Behavior and Serum Biochemical Factors in Adult Male Rats
Nutrition and HealthBackground: Food restriction (FR) and dopaminergic system affect on anxiety behavior, but it has not been determined the...Read more
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Dietary intake of antioxidants in elderly: A case-control study in Iran
Nutrition and HealthNutrient deficiencies such as antioxidants are common problems in elderly subjects which can result in different cancers...Read more
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Investigating the Verification of the Personnel Hand Hygiene Dividedly among Five Situations in Intensive Working in Namazi Hospital of Shiraz
Microbiology and Infectious DiseasesHand hygiene behavior divides into two categories: the innate hand hygiene and the selective hand hygiene. The innate ha...Read more
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Comparison of in vitro survival of mononuclear cells derived from B-CLL patients with or without BAFF & APRILL cytokines
Cancer; Prevention, Diagnosis and TreatmentThis article studies the antiapototic effect of cytokines BAFF & APRIL on the survival of mononuclear cells derived ...Read more
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CLONING AND EXPRESSION OF an antibody fragment (scFv) against PcrV protein of Pseudomonas aeruginosa in fed-batch cultivation mode
Microbiology and Infectious DiseasesPseudomonas aeruginosa is a major cause of hospital-acquired infections, particularly in mechanically ventilated patient...Read more
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Site Directed Mutagenesise of L-Asparagine as an Improveed Anti Cancer Protein with Increased L-ASNase Activity
Cancer; Prevention, Diagnosis and TreatmentL-Asparaginase (L-ASNase) is an FDA approved enzyme which is widely used in fight against acute lymphoblastic leukemia a...Read more
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Relationship between a phenotype and one gene
Medical GeneticsStudy of whole genomes is genomic. The genes contain instructions for protein synthesis that are the functional part of ...Read more
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Molcular Detection of Mupirocin Resistance in Staphylococcus aureus
Microbiology and Infectious DiseasesStaphylococcus aureus has become the most common cause of hospital acquired infections over the last few decades. The ba...Read more
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Expression of NAV2 correlated with Change of tumor size in breast cancer patients
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the first leading cause of cancer death among Iranian women and the second worldwide. This type of canc...Read more
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Hox Genes in Malignant Hematopoiesis in Human- A review
Medical GeneticsHuman beings have 39 HOX genes arranged in four clusters that are located on different chromosomes. These genes are an e...Read more
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Detection of Hepcidin biomarker in plasma of patients with stomach tumor before and after treatment
Cancer; Prevention, Diagnosis and Treatment: cancer is a very important public health problem, which is the main cause of death inindustrialized countries and incr...Read more
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TThe Biological Effects of Aqueous Extract of Ephedra major on the Development of Balb/C Mouse Embryos 7Th to 10Th Days of Pregnancy
Nutrition and HealthAqueous extract of Ephedra major used as a drug for blood pleasure, sleep disorder and lose weight. But it is effects on...Read more
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Investigation of Lead and Chromium Elements in Female Patients with Breast Cancer Before and After Chemotherapy
Cancer; Prevention, Diagnosis and TreatmentHeavy metals such as lead and chromium can be in various forms, including free ions, metal compounds or carcinogenic par...Read more
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Atopic Dermatitis and treatment
Nutrition and Health• diagnostic criteria Atopic dermatitis is difficult to define because of its variable morphology and distribution an...Read more
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The effects of minoxidil on gene expression in the bulb and bulge region of hair follicles by Real time-PCR
BeautyMinoxidil is the most common drug used for treatment androgenic alopecia.Studies have shown that this drug can increase ...Read more
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Motor neuron differentiation potential of human umbilical cord blood- derived mesenchymal stem cells, in vitro
Stem cell and Medical ApplicationsMany people suffer from spinal cord injuries annually. These deficits usually threaten the quality of life of patients. ...Read more
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Targeting the Brain –Surmounting or Bypassing the Blood–Brain Barrier
Nano-Biotech MedicalTheconstituentsoftheblood–brainbarrier,includingitseffluxtransportersystem,canefficientlylimitbrainpenetrationofpotent...Read more
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Antimicrobial susceptibility of Acinetobacter baumannii isolated from different clinical samples in hospitalized patients
Microbiology and Infectious DiseasesAcinetobacter baumannii is a gram negative bacteria, which is cause multidrug-resistant nosocomial infection. Control an...Read more
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Role of Potential tumor marker in several cancer: Diagnostic and Treatment
Cancer; Prevention, Diagnosis and TreatmentTumor markers are substances produced by the tumors or by other cells of the body in response to cancer. They are produc...Read more
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Detecting of herpes simplex virus’s DNA in the breast tumor, using polymerase chain reaction technique
Medical GeneticsIt has been proven that cancer cells formation can be due to the herpes simplex virus infection in human beings. The ai...Read more
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Molecular identification of Aspergillus isolated from livestock feed and poultry using ASAP1 sequencing
Microbiology and Infectious DiseasesThe contamination of livestock feed and poultry with toxic fungi, such as aspergillus in the air and the environment, is...Read more
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An update review about stem cell therapy for diabetes mellitus
Stem cell and Medical ApplicationsMesenchymal stem cells (MSCs) are the most widely used stem cells of the human body because of successful isolation, and...Read more
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Computational analysis and design of crRNA for post transcriptional regulation of metastamiR-10b and metastamiR-126 by CRISPR-C2C2 technique.
Medical GeneticsOne of the important causes of death in cancer patients is metastasis. Recently have been shown that specific group of m...Read more
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Potentiation of mitomycin C-induced apoptosis by lithium chloride in MDA-MB-231 breast cancer cells
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the principle cause of cancer mortality in females. Mitomycin C (MMC), as a potent antitumor drug, is u...Read more
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Serum level of Dipeptidyl peptidase-4 as a potential biomarker for medullary thyroid cancer
Cancer; Prevention, Diagnosis and TreatmentAdipokines are the proteins secreted from adipose tissue which play an important role in the control of metabolism. Dipe...Read more
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Reproductive Health Training Program on Students in IRAN: An Action Research Approach
Women and Reproductive HealthTransition from adolescence to adulthood is one of the important periods in the individual life. New behaviors are learn...Read more
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Overview the Challenges and Development of regenerative medicine in future
Stem cell and Medical ApplicationsMore than 2000clinical trials relating stem cells, there is not a single clinical difficult that is regularly treated wi...Read more
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Therapeutic effects ellagitannin on non communicable diseases
Nutrition and HealthToday, due to the complications caused by the treatment with chemical drugs, the scientists focus on to use of complemen...Read more
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Investigation of synergies effects of albumin- amino penicillin on Staphylococcus aureus MRSA
Nano-Biotech Medicalduring the recent decades, Nanotechnology has entered the field of drug industries and importance of nano-drugs in curin...Read more
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Omega-3 and its effects on colorectal cancer
Cancer; Prevention, Diagnosis and TreatmentCancer as the second leading cause of death has always been a threat to human life and due to its peculiar nature and la...Read more
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Evaluation of Interleukin 10 Gene Promoter Polymorphisms of -592A/C and -1082A/G Region Among Obese Individuals with Type 2 Diabetes in Alborz Province
Metabolism and Metabolic DiseasesToday diabetes is one of the most prevalent noncontagious diseases around the world. There is strong evidence showing in...Read more
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Operational study of plastination as an alternate method for dissection
Nano-Biotech MedicalSince, two-thirds of the approved Zoology Laboratory syllables, defined by the Ministry of Science, Research and Technol...Read more
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Detection of Mycoplasma arginini contamination in biological products by PCR
Microbiology and Infectious DiseasesIntroduction: Mycoplasmas are one of the most important pollutants in biological products and cell cultures, and are a...Read more
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Effect of Valproic Acid on Proliferation and Apoptosis of Colon Cancer HT 29 Cell Line
Cancer; Prevention, Diagnosis and TreatmentThe structure of chromatin is made up of DNA, histones, and non-histone proteins with the basic repeating unit, nucleoso...Read more
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A novel technique to estimate sex ratio in semen
Women and Reproductive HealthOffspring sex is one of the most important factors in controls sex-linked genetically transferred diseases and also for ...Read more
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Epigenetic Mechanisms as Therapeutic Targets
Medical GeneticsEpigenetics, in conjunction with genetic mechanisms, determine the biological fate of cells and living organisms. epig...Read more
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Investigation of toxicity effect of 4-Mepgc and 4-No2pgc on the K562 cell line (chronic myeloid leukaemia)
Cancer; Prevention, Diagnosis and TreatmentLeukemia is a particular type of cancer characterized by the failure of cell death or disability in the differentiation ...Read more
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studying the effect of silibinin in some of hippo signaling pathway genes , in T47D and MCF7 Breast cancer cell lines with 3D culture.
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is one of the most common malignancy diseases world and is the second leading cause of cancer in women. S...Read more
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The study of Apolipoprotein E4 allele distribution in parents of Down's syndrome children as a risk factor in Iran
Medical GeneticsDown syndrome(DS) is the most common chromosomal abnormality.The most important factor in DS is increased maternal age s...Read more
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Evaluation of PRC1 gene expression in gastric cancer patients
Cancer; Prevention, Diagnosis and Treatment: Cancer is one of the most important causes of death. Among cancers, gastric cancer is the fourth most common cancer an...Read more
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Effect of genistein associated with agonist (17-β estradiol) on the viability and apoptosis of human hepatocellular carcinoma HepG2 cell line
Cancer; Prevention, Diagnosis and TreatmentBackground: One of the most lethal cancers is Hepatocellular carcinoma (HCC). Genistein (GE) is a choice compound for tr...Read more
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Prevalence of gastric cancer in the patients undergoing bariatric surgery
Cancer; Prevention, Diagnosis and TreatmentIntroduction and goal: The number of obese people has grown up to 1.9 billion worldwide, that a large number of complica...Read more
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Designing and cloning and expression of bean defensin in human embryonic kidney cells and evaluating their antibacterial function
Microbiology and Infectious DiseasesDefensins are among the most important cationic peptides that their presence in a wide range of herbs and animals has be...Read more
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Benefical Effects of hydroalcoholic extract of fenugreek seeds on some Biochemical factors and oxidative stress in high-fructose diet-induced metabolic syndrome in rats
Metabolism and Metabolic DiseasesBackground: Fenugreek (Trigonella foenum graecum) is a traditional herbal plant. seeds of Fenugreek have several propert...Read more
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Investigation of antioxidant capacity of silver nanoparticles with Laurencia caspica seaweed on liver cancer cell line (HepG2)
Nano-Biotech MedicalHepatocellular carcinoma is a type of hepatocellular carcinoma that occurs most often in cases of hepatitis B and C, or ...Read more
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Combinatorial therapy of anti-Treg vaccine associated with anti-tumor DC vaccine in mice tumor therapy
Cancer; Prevention, Diagnosis and TreatmentRegulatory T cells (Tregs) obviously have a crucial role in attenuation of anti-tumor immune responses. Application of r...Read more
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Interaction of Methotrexate on Stability and structure of Human Serum Albumin
Nano-Biotech MedicalHuman serum albumin(HSA) as the most abundant carrier protein in blood plasma has been widely studied. HSA is often used...Read more
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The effects of nano-liposomes containing curcumin on the lung cancer cell line.
Nano-Biotech MedicalLung cancer is one of the most common and malignant cancer in both sexes. The prevalence and spread of cancer in iran an...Read more
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Efficacy of Bone Marrow Mesenchymal Stem Cells and an Amniotic Membrane on the Number of Mast Cells and Degranulation in Random Skin Flaps in Rats
Stem cell and Medical ApplicationsSkin flap procedures are usually used in plastic surgery. Failing can follow, lead to the necrosis of the flap. Therefor...Read more
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Assessment of energy and water-soluble vitamins intake in the elderly under health care, Isfahan, Iran
Nutrition and HealthThe B vitamins are essential nutrients to maintain nutritionally healthy body. These water soluble vitamins are critical...Read more
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The effects of specific expression of Apoptin under control of PSES and PSA promoter on apoptosis of LNCaP cells
Cancer; Prevention, Diagnosis and TreatmentApoptotic effects of viral protein Apoptin has been demonstrated in numerous studies. However, its tumor specificity has...Read more
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Nephroprotective effect of Lavandula officinalis L. ethanolic extract in alloxan induced diabetic rats
Nutrition and HealthDiabetes mellitus (DM), a metabolic disorder is a major public health problem in both developed and developing countries...Read more
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Anti-Diabetic Effects of Methanolic Extract of Calendula officinalis through Increased Antioxidant Enzymes Activity
Metabolism and Metabolic DiseasesDiabetes is a big challenge in the health care system. ROS generation is the major mechanisms which is involved in the p...Read more
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Kisspeptin decreases mean serum adiponectin concentrations in rats
Women and Reproductive HealthKisspeptin/GPR54 signaling system is one of the most important pathways of hypothalamus for regulating reproductive proc...Read more
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Kidney Cancer, Cancer without Early Symptoms
Cancer; Prevention, Diagnosis and TreatmentThe kidneys are a pair of organs in the human body that are located on either side of the spine and in the lower abdomen...Read more
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The efficacy of Leptin on physical and psychological stress causing gastric ulcer: Participations of nitric oxide and prostaglandin E2
Nutrition and HealthThe present study aimed to assess the effects of Leptin on physical and psychological stresses inducing gastric ulcer. T...Read more
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Survey of beta-lactam hydrolyzing enzymes in Pseudomonas spp. isolated from hospital sewage
Microbiology and Infectious DiseasesBackground: Beta- lactams are the largest group of antibiotics used by hospitals to treat infections caused by Gram-nega...Read more
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Study of PAX5 gene expression in patients with gastric cancer
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is one of the biggest health problems in the world. Due to the lack of many carcinogenic biomarkers and t...Read more
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Evaluation of NTT and Double-Test in screening of Down Syndrome
Women and Reproductive HealthPrenatal diagnosis of genetic, congenital and hereditary diseases is the first step to prevent and control these prob...Read more
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The Bioinformatic prediction of selected miRNAs role in regulation of cell death pathways in Parkinson’s disease
Medical GeneticsParkinson's disease (PD) is the second most common neurodegenerative disease. Due to its unknown etiology and pathology,...Read more
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Synergistic Antibacterial Activity of Zinc Oxide Nanoparticles with Cuminum cyminum L. Essential Oil against the Food-Borne Pathogens Salmonella enterica
Nano-Biotech MedicalOne of the ways to control of pathogenic microorganisms in foods is to use preservatives and antimicrobial agents. Diffe...Read more
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MYH9 gene and urinary albumin excretion in Iranian diabetic patients
Medical GeneticsDiabetic nephropathy (DN) is one of the most common causes of end stage renal disease (ESRD).: Myosin heavy chain 9 (MYH...Read more
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COMPARATIVE STUDY OF OLERACEIN E AND OLERACEIN L EFFECTS ON ANTI OXIDANT ACTIVITY, ANTI DIABETIC INDICATORS AND DAMAGE BIOMARKERS LEVELS IN PANCREATIC CELL LINE
Nutrition and HealthThe medicinal plants have valuable biochemical effects. The aim of this study was to assess the effects of Oleracein E a...Read more
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Green synthesis of Silver nanoparticles by Alhagi camelorum gum
Nano-Biotech MedicalSilver nano particles (AgNPs) are used in textiles, cosmetics, tooth brushes, home appliances, food packages and many ot...Read more
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Additive Cytotoxic Effect of Apoptin and Chemotherapeutic Agent Docetaxel on LNCaP Cell Lines
Cancer; Prevention, Diagnosis and TreatmentUnfortunately although chemotherapy is primary therapy for most types of advanced prostate cancer, conventional chemothe...Read more
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Performing PGD combined with HLA typing on more than 100 blastomeres
Medical GeneticsPreimplantation genetic diagnosis (PGD) is an option for carrier couples who want to assure their child’s health regar...Read more
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Poly(A)-tail shortening Length: an Alternative Epigenetic Mechanism for Translational Control of Oncogenes
Medical Genetics: mRNA poly(A) tails in 3'UTR is important for its stability and translation. t is observed Poly(A) tails is dynamic and...Read more
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Effects of administration of trimethoprim/sulfamethoxazole and folic acid on ovarian histopathology in adult female rats
Women and Reproductive HealthPrevious studies have reported the antifertility activities of sulfonamides. This study was designed to evaluate the eff...Read more
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Evaluation of cardiac differentiation potential of menstrual blood- derived stem cells seeded in biocompatible Bombyx mori silk fibroin scaffold in co-culturing with neonatal rat Cardiomyocytes
Stem cell and Medical ApplicationsCardiovascular disorders are leading cause of million deaths each year which reveals the significance of current limitat...Read more
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Integrin Beta-3 gene polymorphism and risk for myocardial infarction in premature coronary disease
Medical GeneticsContradictory results have been obtained regarding the role of integrin, beta 3 (ITGB3) gene polymorphisms in occurrence...Read more
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The Effect of Educational Intervention on Metabolic Control of Diabetic Patients Referring to the Diabetes Clinic of Shahid Bahonar Hospital in Karaj
Metabolism and Metabolic DiseasesIntroduction: The results of studies on complications and control of diabetes have clearly shown that good metabolic con...Read more
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The role of cabergoline medicine in treating Cushing's syndrome: A systematic review
Metabolism and Metabolic DiseasesCushing's syndrome is an endocrine disorder caused by the excessive production of corticosteroid hormones and adrenocort...Read more
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Determination Of intestinal Escherichia coli Pathotypes Frequency in Tehran Province By PCR
Microbiology and Infectious DiseasesEscherichia coli (E.coli) is an important member of the normal intestinal microflora for mammals, including humans.Diarr...Read more
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The salivary beta-2microglobulin (β2M) and prostate-specific antigen (PSA) can be used as an alternative to the serum β2M and PSA for diagnosis and monitoring of prostate diseases
Cancer; Prevention, Diagnosis and TreatmentIn recent years, the use of saliva as a specimen, due to its non-invasive and easy access increased. But their roles hav...Read more
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Prevalence of Cysticercus bovis in Cattle slaughter-house in Piranshahr city, Iran (2011-2115))
Microbiology and Infectious DiseasesCysticercus bovis are the intermediate stage in the life cycle of a human tapeworm (Taenia saginata). Cysticercus bovis ...Read more
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Neural System Biomarkers
Stem cell and Medical ApplicationsBiomarkers are widely used by physicians, Labradoreans, and scientists. Popular utilization of biomarkers in vivo and in...Read more
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Effect of Zinc nanoparticle on p53 expression in K562 cell line by Real Time PCR
Medical GeneticsChronic myeloid leukemia is a cancer of blood which is identified by bcr/abl translocation. Imatinib is a tyrosine kinas...Read more
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Design And Application Of A Loop-Mediated Isothermal Amplification (LAMP) Assay For Detection Of Tick Borne Relapsing Fever
Medical GeneticsTick borne relapsing fever (TBRF) caused by Borrelia microti is transmitted via bites of the soft tick Ornithodoros erra...Read more
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Ginseng For Improving The Quality Of Life In People With Cancer and Fatigue- A Systematic Review
Cancer; Prevention, Diagnosis and TreatmentBackground and purpose: An important issue in cancer health care is the improvement in quality of life (QoL). Physicians...Read more
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PGD strategy in helping an obligate Hemophilia A carrier woman to have healthy children
Medical GeneticsPreimplantation genetic diagnosis (PGD) is a strategy that has been applied for high-genetic-risk couples with a known g...Read more
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Lantibiotics: New generation of antimicrobial drugs
Microbiology and Infectious DiseasesThese days, due to antibiotic resistance in bacteria, scientists are eager to find new generation drugs. Lantibiotics...Read more
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Evaluation of cytotoxicity of rainbow trout extracts (Oncorhynchus mykiss) on gastric cancer cell line (AGS)
Cancer; Prevention, Diagnosis and Treatmentrainbow trout due to high levels of essential fatty acids, omega-3 has been identified as one of the important factors i...Read more
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New mutation in hotspit region of APC gene in FAP patient in Guilan province
Medical GeneticsFamilial adenomatous polyposis (FAP) is a colorectal cancer predisposition syndrome characterized by the presence of hun...Read more
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Association study of rs369770942 of neuregulin1 gene 3'UTR with schizophrenia
Medical Genetics: Schizophrenia is a mental disorder and affects approximately 1% of global population. This study suggests that rs36977...Read more
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The effects of vitamin D3 supplement on clinical course of patients with migraine
Nutrition and HealthMigraine is one of the most common headaches all around the world including Iran. Considering that some studies have sho...Read more
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Investigation of prevalence class 1 and 2 integron gen in Escherichia coli from Isolated clinical samples Tehran’s hospitals
Microbiology and Infectious DiseasesAs the antibiotics are misused, Integrons are the moving genetic factors which carry resistance gens and have an import...Read more
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Molecular detection of factor 5 Leiden (G1691A) and its relation with TNF- α gene polymorphism in human abortion
Medical GeneticsAbortion is the most common of pregnancy complications. In the pathogenesis of abortion as a multifactorial disease, gen...Read more
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Association of selenoprotein S expression and its variants with metabolic syndrome in subjects with cardiovascular disease
Metabolism and Metabolic DiseasesSelenoproteins S (SELS or VIMP) may regulate cytokine production, and thus play a key role in the control of the inflamm...Read more
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ELISA Cross-Reactivity method to confirm recombinant fliC from salmonella typhimurium and evaluate impurities in purified recombinant protein
Microbiology and Infectious DiseasesRecombinant proteins as important materials for biomedicinal research, need high level of purity in order to be used in ...Read more
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Normal body mass index as a protective factor for osteoporosis after menopause
Nutrition and HealthIncreased body weight is positively related to higher bone mineral density (BMD) in both pre- and post-menopausal women....Read more
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Promoter Hypermethylation Analysis of the Tumor Suppressor Gene RASSF1A in Iranian Endometrial Carcinoma Patients
Cancer; Prevention, Diagnosis and TreatmentEndometrial cancer is the most common malignancy among women in developed countries. More endometrial cancers occurs in ...Read more
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Effect of Biochanin A on retinal angiogenesis and inflammation in STZ induced diabetic rats
Metabolism and Metabolic DiseasesWithout proper medication for the treatment of diabetic retinopathy (DR), retinal cells become malnourished and degenera...Read more
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Modeling of cancer drugs on the route JAK-STAT in cancer stem cells
Cancer; Prevention, Diagnosis and TreatmentAbstract JAK/STAT pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for dev...Read more
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The effect of Thymoquinone on the Cell Cycle and Tumor angiogenesis Process in human breast cancer cell line, MDA-MB-231
Cancer; Prevention, Diagnosis and TreatmentIn recent years, tendency to use phytochemical compounds has been grown dramatically, and more than 25% of drugs used du...Read more
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Frequency of Binding Site at C-Terminal of Helicobacter Pylori CagA Separated from Gastric Tissue Biopsy of Patients with Gastroduodenal Disorders in Shafa Hospital in Khorramabad
Microbiology and Infectious DiseasesHelicobacter pylori (H. pylori) is a gram-negative, microaerophilic bacterium in gastric mucosa. It has a helical shape...Read more
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Cloning of Human THAP11 Gene in Lentiviral Vector
Stem cell and Medical ApplicationsThap11, the most recent described member of THAP domain family, which is in volved in cell proliferation and described a...Read more
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Fertilization rate would be improved after vitrification of immature mouse oocytes
Women and Reproductive HealthVitrification of oocyte is a promising technique to preserve fertility in different species, but it has deleterious effe...Read more
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Recombinant fibroin containing the RGD motif enhances limbal mesenchymal stromal cell adhesion and proliferation
Stem cell and Medical ApplicationsAt the periphery of the cornea, in a region called the limbus, exists a population of stromal progenitor cells termed li...Read more
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Experimental and theoretical investigation on Mandelic acid (R, S) enantioselective separation using Vancomycin chiral column in high performance liquid chromatography
Nano-Biotech MedicalNowadays, antibiotic chiral columns can be used in various chromatography separations. The high potential of these compo...Read more
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Naltrexone changes the expression of lipid metabolism-relatedproteins in the endoplasmic reticulum stress induced hepatic steatosis in mice
Metabolism and Metabolic DiseasesEndoplasmic reticulum (ER) stress is closely associated with several chronic diseases such as obesity, atherosclerosis, ...Read more
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Lipase adsorbtion on the single layer geraphene oxide dependes on pH and temperature
Nano-Biotech Medicalgraphene oxide (GO) has been used as a matrix for lipase immobilization. GO chemical properties are reported beneficial ...Read more
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Association of rs699 Polymorphism in AGT Gene with Coronary Heart Disease Risk
Medical GeneticsThe rs699 transition in human angiotensinogen (AGT) gene, result in methionine (M) to threonine (T) substitution at codo...Read more
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study of mesenchymal stem cell differentiation to chondrocyte on electrospun nanofibrous polyvinyl alcohol alginate sulfat blend
Stem cell and Medical ApplicationsCartilage tissue engineering is used as a potential solution for replacing or repairing damaged tissue. In this method, ...Read more
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Targeted killer gene therapy of breast cancer cells using Pseudomonas exotoxin A
Cancer; Prevention, Diagnosis and TreatmentTargeted expression of killer genes in tumor cells ensures specific elimination of cancer cells with minimal effect on n...Read more
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The Relationship Between Renin- Angiotensin System Genetic Variation and Autism in Iranian Children; A Case –Control Study
Medical GeneticsAutism is a disease of complex nature with a significant genetic component.The importance of Renin-Angiotensin System(RA...Read more
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Evaluation and comparison of digestion in two traditional and contemporary medicine schools And its effect on the treatment of diseases
Nutrition and HealthProper nutrition is one of the principles of "preserving health" in traditional and contemporary medicine. Wha...Read more
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Toll-like receptor 4 mediates cross-talk between peroxisome proliferator-activated receptor γ and nuclear factor-κB in mouse melanoma (B16F10) in vitro
Cancer; Prevention, Diagnosis and TreatmentThere is increasing evidence that chronic activation of nuclear factor-κB (NF-κB), which is an essential signaling pat...Read more
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The effect of 5μM benzoquinone JAG1 and Wnt5a genes in mesenchymal stem cells(MSCs) found in bone marrow(BM) niche
Stem cell and Medical ApplicationsBenzoquinone(BQ) is one of benzene metabolite after entering body, its prolonged presence in body leads to blood disorde...Read more
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The role of Human Papillomavirus Vaccination on cervical cancer: A systematic review
Cancer; Prevention, Diagnosis and TreatmentAccording to International agency for research on cancer (IARC), cervical cancer is the forth reason of death because of...Read more
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Survaey polymorphism rs 866751883 ADAM2 gene infertile men referred to infertility treatment centers in East Azerbaijan which under treatment with IUI (Intrauterine Insemination)
Medical GeneticsOne of the most important genes in human infertility is ADAM2 gene. The gene function is the important in the process of...Read more
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Production and evaluation of scFvs against HER2 antigen for breast cancer immunotherapy
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is common cause of women death in the world. There is ErBb2/HER2 in 25%-30% breast cancer cases. Trastuzu...Read more
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Biosynthesis of Tellurium nanoparticles by Streptomyces isolate B2.1369F
Nano-Biotech MedicalBiosynthesis of Tellurium nano particles (TNPs) has great advantage since it has no chemical contamination in the enviro...Read more
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Investigation of KLF1 gene and It's affection on thalassemia minor patients
Medical Genetics: Thalassemia is a type of hereditary autosomal recessive disorder in which the existing genetic defect reduce the amoun...Read more
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Studying the relation of blood lead level with the thyroid hormones and blood factors
Metabolism and Metabolic DiseasesLead has many applications in the industry but does not play a specific physiological role in the body. According to per...Read more
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Evaluating Anticancer Effects of Tamarix ramosissima on A549 Cells
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the leading cause of cancer death all over the world. Using plant derived materials as folk remedy has be...Read more
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Study of MiRNA-873 expression in Ectopic pregnancy, Endometriosis and Ovarian cancer (review)
Medical GeneticsMicroRNAs are small non-coding RNA molecules that have functions in post-transcriptional regulation of gene expression. ...Read more
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Current Advances in the Genetic Basis of Rheumatoid Arthritis
Medical GeneticsRheumatoid arthritis (RA) is a chronic inflammatory disease characterized by a distinctive pattern of joint involvement ...Read more
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Evaluating the genetic variations in functional domains coding regions of MSMB in infertile men with unexplained infertility
Medical GeneticsΒ-Microseminoprotein(MSMB) is one of the most abundant proteins in human seminal plasma. This protein binds to head and...Read more
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T cell engineering for cancer imenuterapy
Cancer; Prevention, Diagnosis and TreatmentWith regard to the prevalence of cancer in the world, treatment have become important. One of the methods is to stimula...Read more
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Investigating the antitumor activity of PNU-74654 as Wnt/β-catenin inhibitor, alone or in combination with gemcitabine in MiaPaCa-2 pancreatic cancer cell
Cancer; Prevention, Diagnosis and TreatmentWnt/beta-catenin pathway is one of the key dysregulated pathways in several malignancies, including pancreatic cancer (P...Read more
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Production of protein A containing Thiol Group for binding to fluorescence dye To increase the sensitivity of antibody detection
Nano-Biotech Medicalstaphylococcal Protein A is a cell wall component which has the ability to bind to immunoglobulins of different animal s...Read more
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The effect of manual acupuncture on anthropometric parameters in obese and overweight patients
Nutrition and HealthObesity is a chronic disease which is on the increase. Treatments of obesity include diet therapy, exercise, behavior th...Read more
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Cytotoxic evaluation of cumin essential oil on breast cancer cell line (MCF-7)
Cancer; Prevention, Diagnosis and TreatmentCancer can be considered as one of the genetic diseases that reduces the mortality rate in cancer cells in this disease....Read more
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Effect of Staphylococcus aureus isolates in food samples on hep2 cell line
Microbiology and Infectious DiseasesStaphylococcus aureus produces a range of protein-rich toxins and also extracellular pathogens that contribute to bacter...Read more
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Hydroxyapatite-Gelatin-bone marrow stromal cells construct as an excellent bone graft in animal model
Stem cell and Medical ApplicationsBone healing of critical-sized defects are one of the most challenging orthopaedic problems. In the current study, the e...Read more
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Triplet repeats in Androgen receptor and it's relation with cardiovascular disease
Medical GeneticsCardiovascular disease is one of the main cause of death in all around the world and researches indicated that in United...Read more
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Silencing of Mcl-1 and Bcl-2 by miR-15 Induces Apoptosis and Increases the Chemosensitivity of the CLL Cells
Cancer; Prevention, Diagnosis and TreatmentDespite advances in cancer therapy, drug resistance is a major problem in leukemia. Overexpression of anti-apoptotic pro...Read more
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Investigation of C-582 A>G polymorphism at beta globin cluster gene in beta-thalassemia patients
Medical GeneticsThalassemia is the most prevalent monogenic disorder worldwide resulting from the inappropriate production of heme. pati...Read more
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Autism spectrum disorder (ASD) and cancer: both share same genes but different outcomes.
Medical GeneticsAutism spectrum disorder (ASD) is a neurodevelopmental disorder and it is characterized by social and communication prob...Read more
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Insulin resistance in addicted people: experimental study along with in vitro study and data mining Techniques
Metabolism and Metabolic DiseasesThis study was planned to survey the inflammatory and antioxidant and other Insulin Resistance related condition in addi...Read more
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Association between the CYP2E1 polymorphisms and CML risk in Iranian population
Medical GeneticsPolymorphism in the genes encoding detoxification enzymes results in variability to metabolize carcinogens and cause int...Read more
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Identifying Linking Mechanisms of Allergy and Cancer
Cancer; Prevention, Diagnosis and TreatmentAllergy and cancer are prevalent diseases and cause a lot of morbidity and mortality. In recent years, many studies have...Read more
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The role of lipids in the pathogenesis of Human T-cell leukemia virus-1 (HTLV-1) infection: a review of literature
Microbiology and Infectious DiseasesHuman T cell lymphotropic virus-1 (HTLV-1) is an oncogenic retrovirus which can cause adult T-cell leukemia lymphoma (AT...Read more
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The Use of Viruses to Treat Cancer
Cancer; Prevention, Diagnosis and TreatmentCancer is an abnormal growth of cells that have lost normal control mechanisms and are able to expand continuously, inva...Read more
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Design, modeling and simulation of a novel immunotoxin structure affective against gastrointestinal malignancies
Cancer; Prevention, Diagnosis and TreatmentGastrointestinal malignancies comprise a remarkable proportion of cancer deaths each year. Although many drugs have been...Read more
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Mesenchymal stem cells enhance the metastasis of cervical cancer cell line, CaSki, in 3D cell culture system
Cancer; Prevention, Diagnosis and TreatmentMesenchymal stem cells, also known as mesenchymal stromal cells (MSCs), are attractive for repair and regeneration of ti...Read more
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Molecular monitoring of Chronic Myeloid Leukemia in Chronic Phase (CML-CP)
Medical GeneticsQuantification of the BCR-ABL transcript is recommended to follow-up CML patients that treated by Imatinib mesylate (IM)...Read more
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rDKK1 production and purification as an antigen
Cancer; Prevention, Diagnosis and TreatmentA critical goal in prevention and control of cancer is early detection of cancer. It is suggested that the Dickkopf1 (DK...Read more
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Skin anti-ageing potential of Lactobacilli exopolysaccharides (EPSs) on human fibroblast
BeautySkin aging is a complex biological process influenced by a combination of endogenous or intrinsic and exogenous or extri...Read more
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Ischemia-modified albumin as an oxidative stress biomarker in acute coronary syndrome
Metabolism and Metabolic DiseasesFree radicals increasing or Antioxidants decreasing may contribute to impair the equilibrium between oxidant and antioxi...Read more
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Molecular diagnosis of Mycoplasma spp. arthritis by PCR
Microbiology and Infectious DiseasesArthritis is one of the most common inflammatory diseases. It is characterized by symptoms such as systemic inflammation...Read more
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analysis of circulating mir-141, and mir-375 in small cell lung cancer patients
Medical Geneticslung cancer is the main cause of mortality from cancer in the world. small cell lung cancer is the most invasive lung ca...Read more
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Study of HER2 gene expression in AGS cell line after treatment of cells with Crocus sativus (Iranian Saffron) extract
Cancer; Prevention, Diagnosis and TreatmentThe study of HER-2 gene in cancers, especially gastric cancer, is of great importance. This gene, has been shown to inc...Read more
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Effect of intracerebroventricular injection of Adenosine on food and fat intake in neonatal chicks
Nutrition and HealthThe present article was aimed to clarify the role of central Adenosine on food intake in neonatal chicks. Adenosine is n...Read more
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Antioxidants as DNA protective compounds
Nutrition and HealthBased on the recent findings, antioxidants are some essential factors that can have major role on the health. The human...Read more
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Human reovirus destroys liver cancer cell line (Huh-7)
Cancer; Prevention, Diagnosis and TreatmentThe Huh-7 cell line was derived from a liver tumor in a 57-year-old Japanese male patient in 1982. Hepatocellular carcin...Read more
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Classification of Genes Related to Infectious Disease: New Hybrid Method for High Imbalanced Data Sets
Medical GeneticsGene functionality explorations has a great importance in health science research. Developing gene classifiers having ac...Read more
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Function of Diabetes Mellitus on the Body, Diagnosis until Treatment
Medical GeneticsDiabetes mellitus is a metabolic pathway in which the insulin hormone is secreted or incompletely secreted; it is a meta...Read more
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The effect of berberin on histone H1 in lung cancer A549
Cancer; Prevention, Diagnosis and TreatmentBerberin, a naturally occurring isoquinoline alkaloid, is present in a number of important medicinal plants. Berberin ha...Read more
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Study of DNA binding and cytotoxic activity of a benzochromene derivative
Cancer; Prevention, Diagnosis and TreatmentDNA is currently a target for some of the drugs used in cancer therapy. Among the various treatment strategies for remov...Read more
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Investigation of A New Paclitaxel Nano Niosomal formulation and Biological Evaluation of Entrapped Paclitaxel on breast cancer cell line
Nano-Biotech MedicalRegarding that the breast adenocarcinoma is the most widespread disease among women, paclitaxel, an anti-cancer drug, co...Read more
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Design and expression of an immunogenic construct based on calcium sensing receptor antigen
Cancer; Prevention, Diagnosis and TreatmentDue to texture and small size, identifying the parathyroid from thyroid glands is a very difficult procedure. They shoul...Read more
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Expression of CD74 in Ovarian cancer
Medical GeneticsOvarian cancer is a cancer that forms in or on an ovary. The pro-inflammatory cytokine migration inhibitory factor (MIF)...Read more
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Preparation and characterization of Nanofibers Using an Electrospinning Technique as ocular drug delivery
Nano-Biotech MedicalFor the treatment of anterior eye segment infections using anti-infective agents, topical ocular application is the most...Read more
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Gankyrin expression in ovarian cancer and its correlation with clinicopathological parameters
Cancer; Prevention, Diagnosis and TreatmentGankyrin (p28GANK) is a novel oncoprotein which regulates the phosphorylation of retinoblastoma protein (pRb) and degrad...Read more
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Evahuation of Serum Cholesterol as a Component Of Metabolic Syndrome in the Cord Blood of Mothers With Polycystic Ovary Syndrome
Women and Reproductive HealthPolycystic ovary syndrome is one of the most common endocrine disorder among women of reproductive age is the prevalence...Read more
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Evaluation of Acholeplasma laidlawii in biologic products by PCR method
Microbiology and Infectious DiseasesContamination of biological products and cell cultures is one of the important problems in producing a good and safe pro...Read more
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BsmI (rs1544410) polymorphism of vitamin D receptor gene modulates improvement of vitamin D status in overweight women with hypovitaminosis D
Nutrition and HealthThe aim of the present study was to evaluate the possible influence of BsmI (rs1544410) polymorphism of vitamin D recept...Read more
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Green synthesis of Gold nanoparticles by water extract of common nettle leaves
Nano-Biotech MedicalGold nano particles (AuNPs) are being considered for cancer treatments for targeted drug delivery in pharmacology and me...Read more
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Investigation of deaths caused by cancer in Bandar Anzali in 2014
Cancer; Prevention, Diagnosis and TreatmentCancer is one of the main causes of death and disability in Iran and the world. This study was conducted to evaluate the...Read more
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Structural Study of Horseradish Peroxidase upon Interaction with Gold Nanoparticles
Nano-Biotech MedicalRemarkable advancements have been made in the field of nanotechnology, including design of hybrid systems of nanoparticl...Read more
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Detection of Mycoplasma hyorhinis contamination in biological products by PCR method
Microbiology and Infectious DiseasesMycoplasmas are the major contributors to biological products and cell lines throughout the world and are easily able to...Read more
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Analysis of hypermethylation of NFK-B ،TRAF1 and TRAF2 genes in patients with oral squamous cell carcinoma
Medical GeneticsCancer is a fatal disease caused mainly by environmental factors that mutate genes encoding critical cell-regulatory pr...Read more
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Molecular Cloning of Clostridium perfringens Type D & Clostridium septicum vaccine strain epsilon alpha fusion gene in E. coli
Medical GeneticsDesigning and producing a proper fusion construction is the most important problem of producing large quantities of fu...Read more
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Investigation of cytotoxicity, cell cycle and induction of apoptosis by methyl-thiosemicarbazone complex with Cu2+ in K562 cell line
Cancer; Prevention, Diagnosis and TreatmentThiosemicarbazone compounds have previously been considered as a new series of potent apoptosis-inducing agents. In the ...Read more
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Biosynthesis of Silver nanoparticles using water extract of Ziziphus spina_cheristi Leaves
Nano-Biotech MedicalSilver nanoparticles (AgNPs) have been widely used as an antiseptic against a wide range of microorganisms. The goal of ...Read more
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Prognostic significance of c-Myc gene amplification and protein expression in brain tumors: Astrocytoma and meningioma
Cancer; Prevention, Diagnosis and TreatmentAstrocytoma and meningioma are the most common primary brain tumors. c-Myc as a member of MYC proto-oncogenes has recent...Read more
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Prevalence of beta-lactam resistant isolates of Enterobacteriaceae in clinical specimens
Microbiology and Infectious DiseasesBackground: The emergence of extended-spectrum beta-lactamase (ESBL) producing isolates of Enterobacteriaceae has impor...Read more
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Molecular screening for E255K mutations in Imatinib Resistant-CML
Medical GeneticsChronic myelogenous leukemia (CML) is a clonal disease that kind of hematopoietic stem-cell cancer. A significant number...Read more
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Investigation Of Antimicrobial Effect Of Magnetical Silver And Silver-Titanium Dioxide Nanocomposites On Commonly Bacteria Of Urinary Infects
Nano-Biotech MedicalRecently, developed nano composite with highly efficient antimicrobial properties are considered. In this study, A new m...Read more
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A Review Article on Treatment with Stem Cells: Complications and Problems
Stem cell and Medical ApplicationsNowadays, various methods of treatment with stem cells are developing fast while such treatments have different and some...Read more
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Berberine induced cell death of human colon cancer HT-29 through mediating of PARP
Cancer; Prevention, Diagnosis and TreatmentBerberine is an isoquinoline which has many various pharmacological activities, including anticancer activities. Poly (A...Read more
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Effect of Crocin on mitochondrial biogenesis and Oxidative stress in the Striatum of Cholestatic rats
Medical GeneticsOxidative Stress and increment of Mitochondrial Reactive Oxygen Species (ROS) production that occurs in cholestasis whic...Read more
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The Relationship between STR-PCR Chimerism Analysis and Chronic GvHD Following Hematopoietic Stem Cell Transplantation
Cancer; Prevention, Diagnosis and TreatmentGraft-versus-host disease (GvHD) is one of the serious complications of HSCT. Its prevalence has been reported as 20-50 ...Read more
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Comparison of chondrocyte cells survival in alginate and throat fibrin scaffolds using MTT assay for repair and treatment of cartilage
Stem cell and Medical ApplicationsArthritis or osteoarthritis is the most common disease that is counted as the category of arthritis in which the joint c...Read more
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Purification of poly ribosylribotil phosphate capsule from Heamophilus influenza type- b strain ATF2 cultivated in bioreactor
Microbiology and Infectious DiseasesHaemophilus influenzae is a small gram negative cocobacilli non motile and can be seen as pleomorphic. H.inf.can cause ...Read more
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Effect of folic acid supplementation on acute effects of trimethoprim/sulfamethoxazole on histopathological changes in the testes of adult male rats
Stem cell and Medical ApplicationsMale infertility has been reported following long-term sulfasalazine use for ulcerative colitis treatment. However, the ...Read more
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Study of properties of Juglans regia plant on women’s health
Women and Reproductive HealthJuglans regia plant is one of Iranian native plants that some of it’s productive types are in Markazi province. The b...Read more
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Relationship of pre-body mass index with umbilical coiling index in gestational diabetes and non-gestational diabetes mellitus.
Metabolism and Metabolic DiseasesIt has been well documented that overweight or obesity before pregnancy is a strong predictor of gestational diabetes me...Read more
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Development of an Antagonistic TGF-β by Directed Blocking of its TβRI Binding Site to Inhibition TGF-β Signaling
Cancer; Prevention, Diagnosis and TreatmentTransforming growth factors beta (TGF-βs) play vital roles in regulating cell growth, differentiation and inflammation....Read more
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Effect of Hypiran on the oxidative stress responses in experimental autoimmune encephalomyelitis
Nutrition and HealthExperimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis. The hallmark of this disease i...Read more
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A Review of the Fungi Generating the Cellobiose Dehydrogenase Enzyme to Remove Bacterial Biofilms
Microbiology and Infectious DiseasesThe biofilm causes more than 60% of nosocomial infections and 65% human infections. Bacteria in biofilms society are res...Read more
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Evaluation of the effect of saturated and unsaturated fatty acids on the growth and production of outer membrane vesicles in human gut microbiota
Microbiology and Infectious DiseasesA diverse and complex symbiotic microbial community colonize in human host,espicially in the gastrointestinal tract,refe...Read more
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Sensitivity of levofloxacin in combination with ampicillin-sulbactam and tigecycline against multidrug-resistant Acinetobacter baumannii
Microbiology and Infectious DiseasesDuring the last decades, emergence of antibiotic resistance among A. baumannii has been considered as a worldwide alarm....Read more
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Evaluation of circulating prognostic tumor marker DNA in the blood of brain tumor patients
Cancer; Prevention, Diagnosis and TreatmentRecent evidence suggests that tumor cells may release DNA into the circulation, which is enriched in the serum and plasm...Read more
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Effect of Extract of Origanum Vulgare on the activity of alanine aminotransferase enzyme in healthy and diabetic mice
Metabolism and Metabolic DiseasesWild Thyme is a great medicinal plant that grows in different areas of the Mediterranean and some parts of Asia.Present ...Read more
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Influence of CYP2D6 and CYP3A4 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia and treatment response
Cancer; Prevention, Diagnosis and TreatmentXenobiotic- metabolizing enzymes compose an important line of defence against a variety of carcinogenes and environmenta...Read more
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Evaluation of gonadotropin hormones in non-obstructive azoospermia patients
Women and Reproductive HealthInfertility refers to the inability of couples to achieve a successful pregnancy after a year of sexual intercourse with...Read more
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EFFECT OF CHRYSIN NANO-PARTICLES TREATMENT ON ESTROGEN RECEPTORS EXPRESSION LEVELS IN BREAST CANCER CELL LINE
Nano-Biotech MedicalBreast cancer (BC) is increasing in the developing countries. Estrogens are supposed to play roles in BC initiation and ...Read more
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Invitro Effect of Probiotics, Paraprobiotic and Postbiotics of Locally Isolated Lactobacillus casei strains on Colon Cancer Cell Lines
Microbiology and Infectious DiseasesA number of lactic Acid Bacteria (LAB) produce bacteriocin which are bioactive peptides active against a number of path...Read more
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Suppression of interfering predominant bacteria in purification of Myxobacteria
Microbiology and Infectious DiseasesMyxobacteria have recently gained attention due to the ability to produce numerous biological active metabolites. Applyi...Read more
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In silico evaluation of anti-retroviral effects of lactoferrin from different species
Microbiology and Infectious DiseasesLactoferrin (LF) is an iron binding glycoprotein that is present in body fluids and mucosal secretions. Antimicrobial pr...Read more
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Cytotoxic effect of anticancer drug 5-Azacitidine on hematopoietic stem cells of bone marrow in the presence and absence of Colony stimulating factors
Cancer; Prevention, Diagnosis and TreatmentThe cytosine analogue, 5-Azacitidine as a DNA methyltransferase inhibitor is currently considered the most advanced drug...Read more
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Study of gene expression network in varicose veins disease by microarray expression analysis
Medical GeneticsThere is a strong body of circumstantial evidence which implicates genetics in the etiology and pathology of and venous ...Read more
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Polymorphisms evaluation of the thiopurine S-methyltransferase gene among the Iranian acute lymphoblastic leukemia population
Medical GeneticsThiopurine S-methyltransferase (TPMT) is a cytosolic enzyme which catalyzing the S-methylation of 6-mercaptopurine and...Read more
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Down-Regulation of Bcl-2 and Mcl-1 by MiRNA-15 and 16 Synergistically Enhances the Apoptotic Effects of ABT-199 and Fludarabin in CLL Cells
Cancer; Prevention, Diagnosis and TreatmentMiRNA-15 and 16 can act as a tumor suppressor gene by interfering with Bcl-2 and mcl-1. Studies have demonstrated that o...Read more
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Evaluation of cytotoxicity of aqueous-ethanolic extract of pineapple on ovarian cancer cells (A2780 cell line)
Cancer; Prevention, Diagnosis and TreatmentToday, the global trend towards the use of herbal medicines for treating diseases has tended, while developed countries ...Read more
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Application of Nanomaterials in cosmetic industry
BeautyUsing nanotechnology in various fields, like electronics, medicine, and now in cosmetics applications has expanded. Glob...Read more
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Effects of serotonin on adiponectin secretion and leptin gene expresions in rats
Women and Reproductive HealthSerotonin is a neurotransmitter which stimulates the secretion of sexual hormones . The nuclei of Hypothalamus involved...Read more
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Crispr/cas9 a New Approach to Genome Engineering
Medical GeneticsIn 1987, scientists found an acquired immune system in E.coli genome, included series of short repetitive interspaced pa...Read more
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EXPRESSION OF AN ANTIBODY FRAGMENT (SCFV) AGAINST AMYLOID-BETA USING T7 PROMOTER IN FED-BATCH CULTIVATION MODE
Microbiology and Infectious DiseasesIn the current investigation, the expression yield and solubility of Aβ antibody was analyzed using T7 promoter in fed-...Read more
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Effects of Rosmarinic acid on oxidative stress and total antioxidant capacity in vivo study
Metabolism and Metabolic DiseasesDiabetic disease is characterized by chronic hyperglycaemia. Numerous studies have shown that in diabetes mellitus, ther...Read more
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Survey of the Relationship between Two Polymorphisms at Position T677C and C1298A in MTHFR Gene with ADHD in Tehran Children
Medical GeneticsAttention deficit hyperactivity disorder is one of the most common behavioral disorders in children, which is associated...Read more
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Investigation of Interleukin-17 gene polymorphism in patients with gasteric carcinoma and comparsion with healthy individuals reffered parison to the healthy control in Golestan Province 's hospitals.
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is one of the most common types of human cancers globally, which remains an important public health burde...Read more
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Computer aide discrimination of the ovarian lesions by CT scan images
Cancer; Prevention, Diagnosis and TreatmentTo explore diagnostic potential of computerizing texture analysis (TA) methods in discrimination of the normal, benign...Read more
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Neuroprotective nature of adipokine resistin in the early stages of focal cerebral ischemia in a stroke mouse model
Metabolism and Metabolic DiseasesThe goal of the present study was to test the dose-dependent and time-dependent effects of mouse recombinant resistin in...Read more
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the role of genetics in diabetes and its complications
Medical GeneticsThe purposes of writing this article are the significant role of genetics in the onset of diabetes, hoping to be treated...Read more
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Gene Editing: As a new treatment for HIV
Medical GeneticsCurrent treatments in HIV treatment don’t eliminate the low level of viral replication in latently infected cells, whi...Read more
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FGF10: Type III Epithelial Mesenchymal Transition and Invasion in Breast Cancer Cell Lines
Cancer; Prevention, Diagnosis and TreatmentMetastasis is one of the important characteristics of a cancer cell. the process called epithelial mesenchymal transitio...Read more
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Design and evaluation of a colorimetric method for rapid determination of minimal inhibitory concentration of the bacteria belonging to Enterobacteriace
Microbiology and Infectious DiseasesIsolation of antibiotic resistant pathogenic bacteria in clinic may pose the serious problems. So a rapid method capabl...Read more
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Snake venom: an anticancer agent in immunotoxin therapy
Cancer; Prevention, Diagnosis and TreatmentCancer is the second leading cause of death worldwide. Therefore, many studies are underway to innovate more efficient t...Read more
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THE TOLE OF PROBIOTICS IN PUBLIC HEALTH
Nutrition and HealthIn the last decade, we have seen dramatic changes in understanding the role of foods in improving human health. scientif...Read more
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The comparative proteomic pattern study of albumin fraction in type I Gaucher Patients with 2 Dimensional Electrophoresis
Metabolism and Metabolic DiseasesThe gaucher disease is the most common type of lysosomal storage diseases that, particularly affects the macrophage cell...Read more
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Fast detection of Pseudomonas aeruginosa keratitis by Polymerase Chain Reaction (PCR)
Microbiology and Infectious DiseasesPseudomonas aeruginosa is an opportunistic pathogen that has different virulence factors. This organism is commonly foun...Read more
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Evaluation of the level of some of the Trace elements in the sprayer workers
Metabolism and Metabolic DiseasesPesticides and toxins have deleterious effects on human health and can affect the biochemical factors of the body. There...Read more
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personalized medicine in oncology
Medical GeneticsThe term peronalized medicine is used for the identification of optimal drug type and optimal drug dosage for individual...Read more
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Production of recombinant Streptococcal pyogenes exotoxin a protein
Medical GeneticsExotoxin A is one of the toxins which produce by group a streptococcuses. This Toxin is a protein soluble substance whic...Read more
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Gene Bookmarking, a way to detect, predict and control molecular processes
Medical GeneticsGene bookmarking is a mechanism of epigenetic memory for gene expression transmission programs, during cell division. ...Read more
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Evaluation of the HLA-B07 Allelic frequency in the patients with spondyloarthritis syndrome in zanjan province
Medical GeneticsIn 1974 Moll and colleagues established the concept of a group of inter-related disorders originally termed seronegative...Read more
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Apoptotic Effect of Tamoxifen on Hepatocellular Carcinoma Hep G2 Cell Line
Cancer; Prevention, Diagnosis and TreatmentHepatocellular carcinoma (HCC) is the sixth most common cancer, and the third most common cause of cancer-related death...Read more
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the relationship between general and abdominal obesity and advanced glycation end products
Nutrition and HealthAdvanced glycation end products (AGEs) are a heterogeneous group of macromolecules that are formed by the non-enzymatic ...Read more
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Investigating the Epidemiology of Concussed Patients, Hospitalized in Khatam al-Anbyia and Ali ibn Abi Talib Hospitals in Years 95-96
Microbiology and Infectious DiseasesFrom the point of view of frequency and importance, Brain vascularaccidents take the first place among all the neural di...Read more
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A foundation for universal T-cell based adoptive immunotherapy
Cancer; Prevention, Diagnosis and TreatmentThe patient-specific autologous therapy could be a significant limiting factor in the large-scale exploitation of CAR te...Read more
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Investigation the effect of low intensity pulsed ultrasound (LIPUS) on proliferation of G 292 osteosarcoma cells on 3D porous PLGA/β-TCP scaffold within perfusion bioreactor
Stem cell and Medical ApplicationsInvestigation the effect of low intensity pulsed ultrasound (LIPUS) on proliferation of G 292 osteosarcoma cells on 3D p...Read more
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Determination of antibiotic-resistant strains of isolated Brucella in Markazi Province
Microbiology and Infectious DiseasesBrucellosis is one of the common diseases of man and animals are caused by bacteria of the genus Brucella. The purpose o...Read more
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The role of long non-coding RNAs in hematologic malignancies
Cancer; Prevention, Diagnosis and TreatmentLong noncoding RNAs(lncRNAs) are a novel heterogeneous group which refer to non-coding RNA molecule ranging in length fr...Read more
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Thiolated chitosans development and in vitro evaluation of apermeation enhancing oral drug delivery system
Nano-Biotech MedicalThis study investigated the in vitro release of Vancomycin and Amphotericin B fromnovel mocuadhesive chitosan nanofibers...Read more
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Survey of Changes gene expression levels of SAP 1-3 Candida albicans samples treated with treated with Fluconazole-loaded PLGA Nanospheres, in comparsion with drug Fluconazole
Microbiology and Infectious DiseasesSecreted Aspartyl Proteinase (SAP) is one of the main virulent factors in the pathogenesis of Candida. This enzyme is en...Read more
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Doxycycline loaded Kefiran nanofibers: cell viability improvement
Nano-Biotech MedicalDoxycycline (DOXY) is a second generation tetracycline antibiotic with extensive usage. High concentration of DOXY might...Read more
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Optical, structural and antibacterial properties assessment of ZnO:Mn nanoparticles
Nano-Biotech Medicalwith the rapid development of human life, controlling the harmful impacts of microorganisms is essential. The current st...Read more
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Astaxanthin decreases cell viability in MDA-MB-231, but not in non-tumorigenic human breast cell line MCF 10A
Cancer; Prevention, Diagnosis and TreatmentConsidering the high prevalence of breast cancer in Iran, its rising incidence, and the high mortality rate of patients ...Read more
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Combination of ultrasonic waves and dynamic shear stress by design of a novel perfusion bioreactor for 3D bone tissue engineering
Stem cell and Medical ApplicationsIt is shown that mechanical loading by ultrasound enhanced cell proliferation and differentiation. The aim of present st...Read more
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Design and evaluation of a selective delivery system to induce antimiR-155 function
Nano-Biotech MedicalDeveloping RNA/DNA aptamer-miRNA chimera represents an effective approach in targeted gene therapy of cancer. In additio...Read more
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The impact of the vaginal probiotic lactobacillus on the prevention and treatment of cervical cancer
Cancer; Prevention, Diagnosis and TreatmentToday, cervical cancer is the second most common cancer after breast cancer among women and it`s considered dangerous ...Read more
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Association of umbilical coiling index with hypothyroidism and gestational diabetes mellitus.
Metabolism and Metabolic DiseasesGestational diabetes mellitus [GDM] and hypothyroidism are prevalent and potentially serious condition which may put mot...Read more
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Investigating the presence of chemical compounds in pineapple
Cancer; Prevention, Diagnosis and TreatmentPineapple is a member of the Ananasian family, it is a sub-tropical fruit. It has many chemical compounds that are impor...Read more
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Endurance training resulted in significantly greater betatrophin responses compared with resistance training alone, and resistance and endurance exercises combined
Metabolism and Metabolic DiseasesBetatrophin, which recently identified, is a liver and adipose tissue produced hormones that regulates the level of lipi...Read more
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Effect of DNA Demethylating Agent Genistein on Epigenetic-modifying Estrogen Receptor Alpha Gene Expression and Apoptosis Induction and also Cell Viability in Hepatocellular Carcinoma HepG 2 cell line
Cancer; Prevention, Diagnosis and TreatmentIn the normal mammalian cells, epigenetic changes such as DNA methylation and histone acetylation play an important role...Read more
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The link between Bioinformatics approaches and experimental analysis for microRNA target prediction in non-small cell lung cancer
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the first cancer-related cause of death in the world. MicroRNAs are small non-coding small molecules whic...Read more
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MOLECULAR DETECTION OF GUT BACTERIA LACTOBACILLUS, BIFIDOBACTERIA, CLOSTRIDIUM DIFFICILE AND YEAST IN BOWEL DISEASE AND CONTROL PATIENTS
Microbiology and Infectious DiseasesTwo kinds of intestinal disorders included inflammatory bowel disease and irritable bowel syndrome have a strong negativ...Read more
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Diet and lifestyle habit imoact on bone density in postmenopausal women
Nutrition and HealthMenopause is the stage of a woman's life, typically between the ages of 45 and 55, when she stops having menstrual perio...Read more
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The relationship between serum creatinine and creatinine clearance with the occurrence and severity of coronary artery disease
Metabolism and Metabolic DiseasesCardiovascular diseases are thought to be the most important reason of mortality around the world. Among them coronary a...Read more
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One Step Toward Normal Heart Beat By Biological Pacemaker
Medical GeneticsCardiac electrical impulses are generated in sinoatrial node (SAN) which establishes spontaneous action potentials. SAN ...Read more
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Investigation of mutations and polymorphisms in exon 11, 12, 22 and 23 in Non Caucasian cystic fibrosis patients from the north of Iran
Medical GeneticsCystic fibrosis (CF) is the most common autosomal recessive disease in Caucasians, caused by mutation in cystic fibrosi...Read more
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Effect of different Electromagnetic fields (EMF) on sperm viability and motility
Women and Reproductive HealthToday, due to the advancement of the level of technology, electromagnetic fields (EMS) from various industries affect...Read more
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Lack of association between Hypoxia Inducible Factor rs11549465 polymorphism and Preeclampsia
Medical GeneticsPre-eclampsia (PE) is an obstetric disorder that may result inmaternal and neonatal mortality and morbidity. Placental h...Read more
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The association of the H19 rs217727 polymorphism and Preeclampsia
Medical GeneticsPre-eclampsia is a pregnancy specific disorder; which is defined as pregnancy-induced hypertension and proteinuria. H19 ...Read more
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Osteo therapy and the role of chitosan-alginate in osteoarthritis
Nano-Biotech MedicalOsteoarthritis (OA) is a progressive skeleton disturbance that it is usually related with considerable inability and lim...Read more
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The effect of Chlorogenic acid on Insulin, GIP and GLP-1 level in healthy humans: A systematic review
Nutrition and HealthAccording to previous studies, there are different supplements in order to prevent and treat diabetes. These studies sho...Read more
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Toxic effects of Selenite and need to bio removal of it
Nutrition and HealthSelenium is an important micronutrient for human and animal health, however it is toxic slightly above homeostatic requi...Read more
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Association between mtDNA D-Loop Mutation and secondary lung cancer
Cancer; Prevention, Diagnosis and TreatmentLung cancer is one of the leading cause of cancer death in the world. The aim of this study was to determine deletions ...Read more
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Modeling premunition for parasites
Microbiology and Infectious Diseases: Here we are interested in premunition that is an immunologic response in host which provides protection toward some pa...Read more
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Silencing of TIM-3 expression by miR-326 affects apoptosis and proliferation of human HL-60 leukemia cell line
Cancer; Prevention, Diagnosis and TreatmentLeukemia Stem Cells (LSCs) are the main reason for drug-resistance and disease relapse in Acute Myeloid Leukemia (AML). ...Read more
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The effects of methanolic soy extract on ovary tissue modification in model of polycystic ovary syndrome as an inflammation state
Women and Reproductive HealthIntroduction and Objective: Chronic low-grade subclinical inflammation has been increasingly recognized as an interposer...Read more
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Simple solution to prevent prostate cancer
Cancer; Prevention, Diagnosis and TreatmentMen above fifty five years old are at high risk for malignant prostate cancer. Currently surgery is the only treatment a...Read more
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the relationship between hypertension and advanced glycation end products
Nutrition and HealthElevated blood pressure is still one of the major risk factors for diseases and disabilities and also a public heath cha...Read more
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Effect of Zinc Oxide Nanoparticles on expression of proapoptotic BAX and Bcl-2 in Testicular Tissue of NMRI Adult Mice
Nano-Biotech MedicalZinc oxide nanoparticles have numerous applications in medicine and industry. These materials are delivered to the tissu...Read more
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microRNAs as potential biomarkers in early detection of Breast cancer
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is one of most worrisome health problems in women across the world. Its incidence and mortality have under...Read more
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Frequency of [aac(6’)-Ie-aph(2”)] gene and aminoglycosids drug resistance in clinical Staphylococcus aureus isolates by two phenotype and molecular methods
Microbiology and Infectious DiseasesStaphylococcus aureus is one of the most common bacterial infection, these bacteria are an agent of nosocomial and commu...Read more
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Silibinin Inhibits miR-17 in Co-cultured HUVECs with A549 Cell Line
Cancer; Prevention, Diagnosis and TreatmentMicroRNAs are involved in different biological processes including cell proliferation and apoptosis, the two intimately ...Read more
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Study genetic susceptibility polymorphisms for chronic lymphocytic leukemia in Iranian population.
Medical GeneticsChronic lymphoid leukemia (CLL) is the most common form of leukemia found in adults. CLL is a monoclonal disorder that w...Read more
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Determination of GPR55 overexpression by quantitative real-time PCR as a biomarker for skin SCC detection
Cancer; Prevention, Diagnosis and TreatmentChronic wounds resemble the wounds arising with skin squamous cell carcinoma (SCC). Since they are cancerous, they shoul...Read more
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Optimization of the best concentration of Aloe vera extract for treating gastric cancer cells in order to reduce HER-2 gene expression
Cancer; Prevention, Diagnosis and TreatmentHER2 is a glycoprotein that has tyrosine kinase activity and plays an important role in guiding growth signals. Its expr...Read more
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Role of NBD and DBD in P- glycoproteinfunction, a Molecular dynamic simulation
Cancer; Prevention, Diagnosis and TreatmentP-glycoprotein (P-gp) is an ATP-binding cassette (ABC) transporter which belongs to multidrug resistance pump super fami...Read more
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evaluatin of expression of HIF-1alpha gene in various types of colon polyps
Medical GeneticsCancer in iran after cardiovascular diseases and accidents is the yhird leading cause of death. Research has shown that ...Read more
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Characterization of a produced monoclonal antibody against testis antigens on the mouse embryogenesis
Medical GeneticsThe complex series of cellular signaling molecules and transcriptional factors are involved in differentiation and devel...Read more
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Perineal massage during pregnancy and perineal safety during childbirth
Women and Reproductive HealthIntroduction: Women frequently suffer from perineal trauma during childbirth, especially during the first childbirth. ...Read more
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Evaluating the genetic variations of ARPT1 gene in infertile men with abnormality in sperm head morphology referring to Royan institute.
Medical GeneticsThe evaluation of human sperm morphology is a controversial aspect of the semen analysis for the determination of male...Read more
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Microencapsulation and double-coating of probiotic bacteria for enhancement of their viability and targeted delivery
Nutrition and HealthThe purpose of this study was to assess the protecting character of double coated beads of alginate-chitosan-Eudragit S1...Read more
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evaluation of anti-mullerian hormone in daughters of women with polycystic ovary syndrome
Women and Reproductive HealthPolycystic Ovary Syndrome(pcos) is one of the most common endocrine diseases among women during their fertility years . ...Read more
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Evaluation of H.pylori drug resistance to current cure in North-West of Iran
Microbiology and Infectious DiseasesAlmost half of the world population is infected with Helicobacter pylori, a major risk factor for chronic gastritis, pep...Read more
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Nanodispersion-loaded mucoadhesive polymeric inserts for ocular drug delivery: scale up production
Nano-Biotech MedicalFrequent use of highly concentrated solutions may induce toxic side effects and cellular damage at the ocular surface. T...Read more
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Correlation of umbilical coiling index and HbA1C in gestational diabetes mellitus (one-step strategy).
Metabolism and Metabolic DiseasesGestational diabetes mellitus [GDM] is a prevalent and potentially serious condition which may put mothers and fetuses a...Read more
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Evaluation and study of antimicrobial activity of nanoliposomal meropenem against Pseudomonas aeruginosa isolates
Nano-Biotech MedicalThe aim of this study was to evaluate the antimicrobial efficacy of liposomal meropenem formulation against clinical and...Read more
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Differentiation of mesenchymal stem cells to insulin-producing cells with of use to basic culture medium
Metabolism and Metabolic DiseasesDiabetes mellitus type 1 is a form of diabetes mellitus in which not enough insulin is produced. To this date, no defini...Read more
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Investigating the effects of saffron and melatonin with radiotherapy on viability of Hela cells
Cancer; Prevention, Diagnosis and TreatmentCancer is one of the biggest threats to human life. None of cancer treatment have not succeeded completely. One of the n...Read more
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Qualitative and quantitative evaluation of airborne microorganisms and the concentrations of particulate and respirable matter causing from dust storm in the air of Ilam city: cross sectional study
Microbiology and Infectious DiseasesIntroduction: In recent years, dust storms frequently arrived to have large areas of the western half of Iran. Dust part...Read more
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Pharmacogenomics in Multiple sclerosis
Medical GeneticsMultiple sclerosis is a chronic inflammatory disease in the central nervous system. The most effective drugs for MS pat...Read more
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Investigating the absorption of anti-cancer drugs on the surface of the boron nitride nano cage by the dense function theory
Nano-Biotech Medicalmagesterol is a drug used in the treatment of breast and endometrial cancer. Due to the unwanted side effects of this dr...Read more
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Effects of 5-aza-2ˈ-deoxycytidine and Valproic Acid on Epigenetic-modifying DNMT1 Gene Expression, Cell Growth Inhibition and Apoptosis Induction in Hepatocellular Carcinoma WCH-17 cell line
Cancer; Prevention, Diagnosis and TreatmentIntroduction DNA molecule of the eukaryotic cells is found in the form of a nucleoprotein complex named chromatin....Read more
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Preconditioning of bone marrow-derived mesenchymal stem cells by AdipoRon potentiates cell migration ability, in vitro.
Stem cell and Medical ApplicationsMesenchymal stem cells (MSCs) have represented a great potential in recent stem cell-based therapies as well as regenera...Read more
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Green Synthesis of Tellurium nanoparticles by Streptomyces isolate BH8 isolated from soils of Sarcheshmeh Copper Complex, Kerman, Iran
Nano-Biotech MedicalTellurium nano particles (TNPs) have pharmaceutical, medical, industrial and environmental importance. Tellurium has als...Read more
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Dendrosomal curcumin nanoformulation modulate apoptosis-related genes and protein expression in hepatocarcinoma cell lines.
Nano-Biotech MedicalIntroduction: The side-effects observed in conventional therapies have made them unpromising in curing Hepatocellular c...Read more
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The levels of VDBP in patients with chronic rhinosinusitis with polyposis
Medical GeneticsChronic rhinosinusitis (CRS) is a prevalent disease which is characterized by chronic inflammation of the nasal mucosa ...Read more
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The effect of diet in preventing of colorectal cancer: A systematic Review
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer (CRC) is the third most commonly diagnosed cancer in worldwide and it is established that diet has an ...Read more
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Antibody-drug conjugates; a Novel class of cancer treatment
Cancer; Prevention, Diagnosis and TreatmentOne of the most effective therapeutic agents used in targeted cancer therapies is antibody. Due to lack of permeability ...Read more
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In silico cancer therapy by using genome editing tool: CRISPR/Cas9
Cancer; Prevention, Diagnosis and TreatmentGiven the fact that cancer today has a broad spectrum of diseases in the populations, and also by relying on the fact th...Read more
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The effect of vinorelbine on HMG proteins in lung cancer A549 cells
Cancer; Prevention, Diagnosis and TreatmentVinorelbine is a semisynthetic vinca alkaloid antitumor drug, widely used in the treatment of cancers such as advanced n...Read more
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Non-muscle Myosin Heavy Chain 9 Gene (MYH9) Polymorphism (rs4821481) is Associated with Urinary Albumin Excretion in Iranian Diabetic Patients
Medical GeneticsMyosin heavy chain 9 (MYH9) gene polymorphisms have been implicated in a different type of renal disease as well as neph...Read more
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Evaluation of Catalase (CAT) expression in Acute Myeloid leukemia Patients
Cancer; Prevention, Diagnosis and TreatmentAcute myeloid leukemia is a heterogeneous neoplastic malignancy, that despite considerable progress in many of its molec...Read more
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The Evaluation of Methicillin Resistant Staphylococcus aureus (MRSA) Colonization on Skin Lesions in Patients with Psoriasis
Microbiology and Infectious DiseasesPsoriasis is a chronic and inflammatory disease of the skin. Recently, the role of microbial agents in the development o...Read more
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The Effect of Vitamin D on Diabetes Mellitus: A Systematic Review
Metabolism and Metabolic Diseases: Diabetes Mellitus is a common metabolic and non-infectious disorder that affects around 346 million people worldwide w...Read more
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Investigating the toxicity of PEGylated Gold Nanoparticles and red LED light on Ecoli bacteria
Nano-Biotech MedicalToday, the emergence and spread of antibiotic-resistant strains of bacteria have become a major challenge to public heal...Read more
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Self-Concept among Infertile women receiving oocyte donation and Fertile Women
Women and Reproductive HealthOne of the technologies used to assist fertility is oocyte donation. Although there is sufficient information about med...Read more
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Impact of CYP3A5 and CYP3A4 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia and treatment response
Medical GeneticsCYP3A5 and CYP3A4 are the members of the CYP3A gene family which metabolizes 50% of therapeutic drugs and steroid hormon...Read more
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Using micronuclei assay in cancer treatment
Medical GeneticsCancer is one of the leading causes of illness and mortality worldwide, after cardiovascular disease. There are differen...Read more
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Explaining Women's Views on Cervical Cancer: A Qualitative Study
Cancer; Prevention, Diagnosis and TreatmentCervical cancer is the second most common cancer in the world , Which, if detected and treated at early stages, is almo...Read more
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Protective effect of silymarin on plasma membrane and DNA integrity of human sperm treated with cadmium chloride
Women and Reproductive HealthCadmium, as an environmental pollutant, exerts its destructive effects on male reproductive system and sperm by inducing...Read more
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Relationship between Hypertension in the First Trimester of Pregnancy with Weight and Height at Birth
Women and Reproductive HealthBackground: Hypertensive disorders with a prevalence of %5-10 are among the main causes of morbidity and mortality in mo...Read more
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A genetic variant in Multiple drug resistance gene is associated with poor prognosis of patients with esophageal squamous cell carcinoma
Cancer; Prevention, Diagnosis and TreatmentEsophageal squamous cell carcinoma (ESCC) is one of the causes of death from cancer. Several genetic variants in the 7q2...Read more
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Investigating the expression alteration of long non-coding RNA GNAS-AS1 of breast cancer specimen
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the most common cancer in women, and due to high rates of invasion and metastasis in these patients, th...Read more
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A technical overview on the neuronal dysfunction induced by heat stroke on the C57 mice models
Medical GeneticsHeat is an environmental hazard that via increasing core body temperature leads to innate stress with pathological and p...Read more
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Prognostic value of MSI status in colorectal cancer patients
Cancer; Prevention, Diagnosis and TreatmentMicrosatellite instability (MSI) causes hereditary non-polyposis colorectal cancer (HNPCC), and occurs in about 15 per c...Read more