Studying the relation of blood lead level with the thyroid hormones and blood factors
Hanieh Babaei,
1 Maryam sadat daneshpour,
2,* Maryam ghobeh,
3
1. Department of Biology, Science and Research Branch, Islamic Azad University
2. Associate prof and vice-chancellor of Cellular and Molecular Endocrine Research Center, Shahid Beheshti University of me
3. Department of Biology, Science and Research Branch, Islamic Azad University
Abstract
Introduction
Lead has many applications in the industry but does not play a specific physiological role in the body. according to performed studies, lead has an undesirable effect on the nervous, gastrointestinal, respiratory, and endocrine systems. people who are highly exposed to this element, due to their occupation or living place, are affected by its harmful effects. the aim of this study was to evaluate the level of thyroid hormones and blood cells in people highly exposed to lead.
Methods
This cross-sectional study was carried out on 37 patients with high exposure level to lead in tehran. after filling out the consent form and questionnaire, the blood samples were collected from them and their levels of blood lead, thyroid hormones and blood parameters were evaluated in a laboratory. normal distribution of data was assessed by kolmogorov smirnov test by med calc 14.8.1.
Results
Obtained results demonstrated that there was no significant association between blood lead levels and levels of thyroid hormones, number of blood cells and related blood cells parameters (hct, hgb, mcv, mch and mchc) in this study. however, according to kolmogorov smirnov test by med calc 14.8.1, there was a weak link between blood lead levels and age (r = 0.25).
Conclusion
high lead levels did not affect the level of the thyroid hormones, the number of blood cells and the levels of the red blood cells parameters in this cross-sectional study.
Keywords
Lead, thyroid hormones, blood cells, hemoglobin, hematocrit.
