Determination of antibiotic-resistant strains of isolated brucella in markazi province

Puran Badkoobeh,1 Davud hosseini,2,* Maryam azizpur,3

1. iran-farhangian university
2. Razi Vaccine & Serum Research Institute Central Area branch(Arak), Iran



Brucellosis is one of the common diseases of man and animals are caused by bacteria of the genus brucella. the purpose of this study was to split and determine antibiotic susceptibility and resistance of brucella isolated in the markazi province


In this study during the spring and summer of 2014, a total of 80 samples from suspected human and animal brucellosis 71 isolates were obtained and subjected to determine antibiotic resistance pattern using disk diffusion method.


With antibiogram testing, samples were sensitive to minocycline, gentamicin, tigecycline, 100% and to doxycycline as 94.37% compared to ceftriaxone, cefixime, streptomycin and chloramphenicol 73.24%, for rifampin; 46.48%, erythromycin, 32.39% and were resistant 100% to cloxacillin.


According to the conculusion in this area, rifampine, erythromycin and cloxacillin can’t be as perfect drugs for treatment of brucellosis in this province and maybe prescription of them cause to increase illness or failure of treatment.


Brucellosis, zoonosis, antibiotic resistance, disk diffusion