Antimicrobial susceptibility of acinetobacter baumannii isolated from different clinical samples in hospitalized patients

Akram sadat Mousavi sani,1,*



Acinetobacter baumannii is a gram negative bacteria, which is cause multidrug-resistant nosocomial infection. control and treatment of infections induced by acinetobacter baumannii is a major problem due to development of a rapid resistance. the aim of present study was to investigate the acinetobacter baumannii antibiotic resistance in the different section of the hospital


In this cross-sectional study, 71 isolates of acinetobacter were collected from urine, blood, wound, aspirated sputum, ascites and trachea in 2015-2016. identification of isolates at the genus level were performed by standard biochemical methods and at the species level by polymerase chain reaction (pcr) . finally, antibiotic susceptibility was determined against antibiotics.


: according to the antibiotic susceptibility testing, 65 isolates (94.2%) out of 69 acinetobacter baumannii isolates were resistant to ceftazidim which was the highest rate of resistance. the lowest resistance was related to polymyxin b and all isolates were susceptible to this antibiotic.


: it can be concluded that, prescribing and overusing of antibiotics have led to increased resistance of opportunistic pathogens. colistin and polymyxin b are the only effective antibiotics against acinetobacter baumannii. accordingly, combination of these antibiotics along with others might be useful for treatment of the infections.


Acinetobacter baumannii, antibiotic resistance, microbial sensitivity tests