Amir Avan
,
Abstracts, [Author]
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Non-syndromic obesity in infertile men and structural chromosomal abnormalities
Medical GeneticsObesity is commonly classified into subgroups depending on suspected etiology: monogenic obesity (extremely severe obesi...Read more
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Silencing of Mcl-1 and Bcl-2 by miR-15 Induces Apoptosis and Increases the Chemosensitivity of the CLL Cells
Cancer; Prevention, Diagnosis and TreatmentDespite advances in cancer therapy, drug resistance is a major problem in leukemia. Overexpression of anti-apoptotic pro...Read more
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Controversy in reports about TNF-α (rs361525) related to susceptibility to Hepatocellular Carcinoma (HCC): a meta-analysis
Cancer; Prevention, Diagnosis and TreatmentTumor necrosis factor-α play a very important role in the development and progression of hepatocellular carcinoma. Pre...Read more
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Anemia, a common disease in hemodialysis patients
Metabolism and Metabolic DiseasesChronic renal failure stage of renal insufficiency it is said that all the no longer able to repel and not toxic waste a...Read more
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Prevalence of septicemia in Intasive care unit and Internal medicine wards patients in Rajaee Hospital of Karaj
Microbiology and Infectious DiseasesSepticemia or blood infections is One of the most important causes of death in patients hospitalized in different parts...Read more
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The levels of VDBP in patients with chronic rhinosinusitis with polyposis
Medical GeneticsChronic rhinosinusitis (CRS) is a prevalent disease which is characterized by chronic inflammation of the nasal mucosa ...Read more
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Survey of the Relationship between Two Polymorphisms at Position T677C and C1298A in MTHFR Gene with ADHD in Tehran Children
Medical GeneticsAttention deficit hyperactivity disorder is one of the most common behavioral disorders in children, which is associated...Read more
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Study of gene expression network in varicose veins disease by microarray expression analysis
Medical GeneticsThere is a strong body of circumstantial evidence which implicates genetics in the etiology and pathology of and venous ...Read more
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Identification of the gene involved in over-production of a novel lipopeptide in an over-expressed mutant of Pseudomonas gingeri
Microbiology and Infectious DiseasesLipopeptides as secondary metabolites, produced by Pseudomonads, can be used as biosurfactants and antimicrobial drugs i...Read more
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Genotyping of Escherichia coli strains isolated from hospitals sewage
Microbiology and Infectious DiseasesToday one of the most common problems in the health society is the way of treating multidrug resistant (MDR) organisms. ...Read more
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Relation between Resilience and Psychiatric Disorders in Patients with Aids in Bandar Abbas Center for Behavioral Diseases
Nutrition and HealthThe AIDS process is very complex and can significantly affect the physical, social, spiritual and psychological health o...Read more
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Molecular markers in the diagnosis of lung cancer
Cancer; Prevention, Diagnosis and Treatmentlung cancer is the leading cause of cancer-related mortality, one of the main causes of mortality by 2010. There are sev...Read more
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BRCC2 gene inhibits lung cancer cell proliferation and invasiveness in vitro and in vivo:Prospect for gene therapy
Cancer; Prevention, Diagnosis and TreatmentLung cancer is one of the major causes of cancer related death worldwide .Despite recent improvements, resistance to con...Read more
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The role of long non-coding RNAs in hematologic malignancies
Cancer; Prevention, Diagnosis and TreatmentLong noncoding RNAs(lncRNAs) are a novel heterogeneous group which refer to non-coding RNA molecule ranging in length fr...Read more
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Effect of vitamin E on liver index enzymes in normal and CCl4-intoxified male Wistar rats
Nutrition and HealthVitamin E is the key lipid-soluble antioxidants in humans. Vitamin E supplementation was effective in decreasing markers...Read more
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Isolation and identification of probiotic bacteria from human milk
Microbiology and Infectious DiseasesBackground: Breast milk is the best nutritional supplement during the first few months of the baby's life. It contains v...Read more
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Braest cancer micrometastatic detection in sentinele lymph nodes using molecular marker
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is prevalent malignancy among women in worldwide (1). Molecular diagnosis is recently proposed as a sensit...Read more
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Surface modification of Chitosan nano-fiber by cold atmospheric plasma
Nano-Biotech MedicalSurface modification is the act of modifying the surface of a material by bringing physical, chemical or biological char...Read more
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Cloning and expression of recombinant Cecropin A in Nicotiana tabacum L. hairy roots and its antimicrobial properties
Microbiology and Infectious DiseasesCecropins are a group of antimicrobial peptides (AMP) derived from innate immune system of various multicellular organis...Read more
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Crispr/cas9 a New Approach to Genome Engineering
Medical GeneticsIn 1987, scientists found an acquired immune system in E.coli genome, included series of short repetitive interspaced pa...Read more
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Investigation efflux pump -activated fluoroquinolone resistance in pseudomonas aeroginosa multi drug resistance isolates by CCCP inhibitor
Microbiology and Infectious DiseasesPseudomonas aeruginosa is the third cause of nosocomial infections after Staphylococcus aureus and E. coli .One of the p...Read more
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Anticonvulsant, neuroprotective and behavioral effects of magnesium sulfate on pentylenetetrazol-induced seizures in male Wistar rats
Nutrition and HealthMagnesium (Mg2+) is the second most abundant divalent and ubiquitous intracellular cation in mammalian cells and an ess...Read more
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Relationship between a phenotype and one gene
Medical GeneticsStudy of whole genomes is genomic. The genes contain instructions for protein synthesis that are the functional part of ...Read more
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The Use of Viruses to Treat Cancer
Cancer; Prevention, Diagnosis and TreatmentCancer is an abnormal growth of cells that have lost normal control mechanisms and are able to expand continuously, inva...Read more
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Evaluation of gonadotropin hormones in non-obstructive azoospermia patients
Women and Reproductive HealthInfertility refers to the inability of couples to achieve a successful pregnancy after a year of sexual intercourse with...Read more
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Silencing of TIM-3 expression by miR-326 affects apoptosis and proliferation of human HL-60 leukemia cell line
Cancer; Prevention, Diagnosis and TreatmentLeukemia Stem Cells (LSCs) are the main reason for drug-resistance and disease relapse in Acute Myeloid Leukemia (AML). ...Read more
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Differentiation of mesenchymal stem cells to insulin-producing cells with of use to basic culture medium
Metabolism and Metabolic DiseasesDiabetes mellitus type 1 is a form of diabetes mellitus in which not enough insulin is produced. To this date, no defini...Read more
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Prognostic significance of c-Myc gene amplification and protein expression in brain tumors: Astrocytoma and meningioma
Cancer; Prevention, Diagnosis and TreatmentAstrocytoma and meningioma are the most common primary brain tumors. c-Myc as a member of MYC proto-oncogenes has recent...Read more
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Antibacterial properties of saffron
Microbiology and Infectious DiseasesSaffron is a small herb of the Welsh family. This is a plant with spherical onions which surrounded by a brown membrane....Read more
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RNY12 peptidomimetic increases SH-SY5Y Neuronal Survival Comparable to BDNF
Stem cell and Medical ApplicationsBrain-derived neurotrophic factor (BDNF) activates downstream cell signaling pathways through TrkB receptor and triggers...Read more
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Some candidate Biomaterials for Amniotic Membranes (AM) Regeneration: a review
Stem cell and Medical ApplicationsAmniotic Membranes (AM) wich form the amniotic sac filled by amniotic fluid and completely surrounds the embryo/fetus. I...Read more
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The effect of berberin on histone H1 in lung cancer A549
Cancer; Prevention, Diagnosis and TreatmentBerberin, a naturally occurring isoquinoline alkaloid, is present in a number of important medicinal plants. Berberin ha...Read more
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Survey of Changes gene expression levels of SAP 1-3 Candida albicans samples treated with treated with Fluconazole-loaded PLGA Nanospheres, in comparsion with drug Fluconazole
Microbiology and Infectious DiseasesSecreted Aspartyl Proteinase (SAP) is one of the main virulent factors in the pathogenesis of Candida. This enzyme is en...Read more
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Integrin Beta-3 gene polymorphism and risk for myocardial infarction in premature coronary disease
Medical GeneticsContradictory results have been obtained regarding the role of integrin, beta 3 (ITGB3) gene polymorphisms in occurrence...Read more
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Experimental and theoretical investigation on Mandelic acid (R, S) enantioselective separation using Vancomycin chiral column in high performance liquid chromatography
Nano-Biotech MedicalNowadays, antibiotic chiral columns can be used in various chromatography separations. The high potential of these compo...Read more
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Suppression of interfering predominant bacteria in purification of Myxobacteria
Microbiology and Infectious DiseasesMyxobacteria have recently gained attention due to the ability to produce numerous biological active metabolites. Applyi...Read more
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Study of DNA binding and cytotoxic activity of a benzochromene derivative
Cancer; Prevention, Diagnosis and TreatmentDNA is currently a target for some of the drugs used in cancer therapy. Among the various treatment strategies for remov...Read more
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Preparation and characterization of Nanofibers Using an Electrospinning Technique as ocular drug delivery
Nano-Biotech MedicalFor the treatment of anterior eye segment infections using anti-infective agents, topical ocular application is the most...Read more
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Astaxanthin decreases cell viability in MDA-MB-231, but not in non-tumorigenic human breast cell line MCF 10A
Cancer; Prevention, Diagnosis and TreatmentConsidering the high prevalence of breast cancer in Iran, its rising incidence, and the high mortality rate of patients ...Read more
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Mediterranean dietary pattern adherence modify the association between FTO genetic variations and obesity phenotypes
Nutrition and HealthThere is an increasing interest in examining whether dietary patterns modify the association of fat mass and obesity ass...Read more
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Targeting the Brain –Surmounting or Bypassing the Blood–Brain Barrier
Nano-Biotech MedicalTheconstituentsoftheblood–brainbarrier,includingitseffluxtransportersystem,canefficientlylimitbrainpenetrationofpotent...Read more
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Antioxidants as DNA protective compounds
Nutrition and HealthBased on the recent findings, antioxidants are some essential factors that can have major role on the health. The human...Read more
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The giant lipoma pediculated in the falciform ligament: a case report
Cancer; Prevention, Diagnosis and TreatmentIntroduction: Lipoma is one of the benign and common tumors of the limbs and trunk that’s rarely occurs in the abdomin...Read more
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Serum level of Dipeptidyl peptidase-4 as a potential biomarker for medullary thyroid cancer
Cancer; Prevention, Diagnosis and TreatmentAdipokines are the proteins secreted from adipose tissue which play an important role in the control of metabolism. Dipe...Read more
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Molecular mechanism of alpha-2 adrenergic receptors in locus Coeruleus
Medical GeneticsPain is one of the most common forms of psychological stress and the most common phenomenon in medical science. Analgesi...Read more
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Berberine induced cell death of human colon cancer HT-29 through mediating of PARP
Cancer; Prevention, Diagnosis and TreatmentBerberine is an isoquinoline which has many various pharmacological activities, including anticancer activities. Poly (A...Read more
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Ginseng For Improving The Quality Of Life In People With Cancer and Fatigue- A Systematic Review
Cancer; Prevention, Diagnosis and TreatmentBackground and purpose: An important issue in cancer health care is the improvement in quality of life (QoL). Physicians...Read more
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The role of artificial intelligence in medical decisions
Nano-Biotech MedicalThe term "artificial intelligence" was used in 1956. There is still no definitive definition of artificial intelligence ...Read more
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Toll-like receptor 4 mediates cross-talk between peroxisome proliferator-activated receptor γ and nuclear factor-κB in mouse melanoma (B16F10) in vitro
Cancer; Prevention, Diagnosis and TreatmentThere is increasing evidence that chronic activation of nuclear factor-κB (NF-κB), which is an essential signaling pat...Read more
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The Study of the Frequency of Antibiotic Usage as an Important Factor in Appearing Antibiotic Resistance in All of the Units in Namazi Hospital
Microbiology and Infectious DiseasesAs the unusual increase in using antibiotics has been suggested as an indicative factor in appearing antibiotic resistan...Read more
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Development of an Antagonistic TGF-β by Directed Blocking of its TβRI Binding Site to Inhibition TGF-β Signaling
Cancer; Prevention, Diagnosis and TreatmentTransforming growth factors beta (TGF-βs) play vital roles in regulating cell growth, differentiation and inflammation....Read more
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Comparison of antimicrobial activity of hydroalcoholic extract of fig(Ficus carica) against Staphylococcus aureus(MSSA & MRSA) with some antibacterial drugs
Microbiology and Infectious DiseasesStaphylococcus aureus is one of the five most common causes of hospital infections and death the worldwide. The excessiv...Read more
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A brief review of regenerative dentistry
Stem cell and Medical ApplicationsTissue regeneration idea has been formed by stem cells identifying and tissue engineering techniques. Stem cells can be ...Read more
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FGF10: Type III Epithelial Mesenchymal Transition and Invasion in Breast Cancer Cell Lines
Cancer; Prevention, Diagnosis and TreatmentMetastasis is one of the important characteristics of a cancer cell. the process called epithelial mesenchymal transitio...Read more
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Stress-induced immobility in male and female rats and its effects on offspring numbers, sex ratios and sexual hormones
Women and Reproductive HealthStress-induced immobility inhibition of reproductive functions and can effect on sexual hormones. Increasing/decreasing ...Read more
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Streptococcus mutans detection in Dental Plaque and saliva Samples
Microbiology and Infectious DiseasesDental caries is one of the most common prevailing disease in humans and a significant public health problem worldwide. ...Read more
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Evaluation of cytotoxicity of rainbow trout extracts (Oncorhynchus mykiss) on gastric cancer cell line (AGS)
Cancer; Prevention, Diagnosis and Treatmentrainbow trout due to high levels of essential fatty acids, omega-3 has been identified as one of the important factors i...Read more
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A novel technique to estimate sex ratio in semen
Women and Reproductive HealthOffspring sex is one of the most important factors in controls sex-linked genetically transferred diseases and also for ...Read more
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Promoter Hypermethylation Analysis of the Tumor Suppressor Gene RASSF1A in Iranian Endometrial Carcinoma Patients
Cancer; Prevention, Diagnosis and TreatmentEndometrial cancer is the most common malignancy among women in developed countries. More endometrial cancers occurs in ...Read more
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Antibody-drug conjugates; a Novel class of cancer treatment
Cancer; Prevention, Diagnosis and TreatmentOne of the most effective therapeutic agents used in targeted cancer therapies is antibody. Due to lack of permeability ...Read more
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Role of NBD and DBD in P- glycoproteinfunction, a Molecular dynamic simulation
Cancer; Prevention, Diagnosis and TreatmentP-glycoprotein (P-gp) is an ATP-binding cassette (ABC) transporter which belongs to multidrug resistance pump super fami...Read more
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Mortality effect of Silibinin on the A549 cell line
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the leading cause of cancer death in the world, with 1,375,000 deaths annually. Common chemotherapy such ...Read more
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Impact of CYP3A5 and CYP3A4 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia and treatment response
Medical GeneticsCYP3A5 and CYP3A4 are the members of the CYP3A gene family which metabolizes 50% of therapeutic drugs and steroid hormon...Read more
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Interaction of rs783540 of CPEB1 gene in patients with azoospermia
Medical Genetics: Publicly, 90% of fertile couples get pregnant in one year. Therefore, infertility refers to disability in pregnancy, a...Read more
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Tuberculosis is a common HIV infection, control and treatment
Microbiology and Infectious DiseasesPoints out Pulmonary that more than all the be without lymph node, pylorus , Urinary tract , bones and joints , meninge...Read more
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Study of MiRNA-873 expression in Ectopic pregnancy, Endometriosis and Ovarian cancer (review)
Medical GeneticsMicroRNAs are small non-coding RNA molecules that have functions in post-transcriptional regulation of gene expression. ...Read more
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Intervention of Dopamine D2 Receptors in Regulating the Serum Lipid Profile in Male Rats under Food Restrictions
Nutrition and HealthStudies have indicated that reduced energy consumption mostly has a significant effect on the reduction of blood lipids...Read more
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The role of Human Papillomavirus Vaccination on cervical cancer: A systematic review
Cancer; Prevention, Diagnosis and TreatmentAccording to International agency for research on cancer (IARC), cervical cancer is the forth reason of death because of...Read more
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EFFECT OF CHRYSIN NANO-PARTICLES TREATMENT ON ESTROGEN RECEPTORS EXPRESSION LEVELS IN BREAST CANCER CELL LINE
Nano-Biotech MedicalBreast cancer (BC) is increasing in the developing countries. Estrogens are supposed to play roles in BC initiation and ...Read more
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Effect of LPS on regulatory T cell induction in peripheral blood mononuclear cells of endometriosis patients
Women and Reproductive HealthEndometriosis is an estrogen-dependent chronic inflammatory disease affecting women of reproductive age. Regulatory T ce...Read more
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Rosmarinic acid, a Anti-glycation agent, inhibits protein glycation in vitro
Metabolism and Metabolic DiseasesDiabetes mellitus is one of the most non-communicable diseases and is the fifth leading causes of death in most of the d...Read more
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Investigation of cytotoxicity, cell cycle and induction of apoptosis by methyl-thiosemicarbazone complex with Cu2+ in K562 cell line
Cancer; Prevention, Diagnosis and TreatmentThiosemicarbazone compounds have previously been considered as a new series of potent apoptosis-inducing agents. In the ...Read more
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Comparative investingation of effects of the agricultural pesticides (diazinon and chlorpyrifos) on spermatogenesis in male BALB/c male mice
Nutrition and HealthDiazinon and chlorpyrifos are kind of organophosphate toxins used for agricultural pests. These toxins control acetylch...Read more
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An investigation on the structure and function of the cell surface breast-specific antigens for development a new generation of immunotoxins
Cancer; Prevention, Diagnosis and TreatmentBreast cancer with heterogeneous features in morphology, clinic, and responses to therapeutic options, is one of the mos...Read more
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Expression of CD74 in Ovarian cancer
Medical GeneticsOvarian cancer is a cancer that forms in or on an ovary. The pro-inflammatory cytokine migration inhibitory factor (MIF)...Read more
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Removal of Nickel (II) From Drinking Water Using Thiol-Functionalized Chitosan
Nano-Biotech MedicalSome heavy metals are the causes of various diseases among humans. Thus, removing heavy metals is necessary in order to ...Read more
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The Evaluation of Methicillin Resistant Staphylococcus aureus (MRSA) Colonization on Skin Lesions in Patients with Psoriasis
Microbiology and Infectious DiseasesPsoriasis is a chronic and inflammatory disease of the skin. Recently, the role of microbial agents in the development o...Read more
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Treatment of vitamin D deficiency in pregnancy
Women and Reproductive HealthThe purpose of this study is the importance of Vitamin D in pregnancy and its treatment. Serum levels of Vitamin D in th...Read more
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Evaluation of magnesium & copper levels and antioxidant power in serum of women with endometriosis before and after administration of N-acetylcysteine
Women and Reproductive HealthEndometriosis is caused by the presence of ectopic endometrial stromal outside the endometrial cavity. The oxidative str...Read more
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Production of recombinant Streptococcal pyogenes exotoxin a protein
Medical GeneticsExotoxin A is one of the toxins which produce by group a streptococcuses. This Toxin is a protein soluble substance whic...Read more
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Dietary intake of antioxidants in elderly: A case-control study in Iran
Nutrition and HealthNutrient deficiencies such as antioxidants are common problems in elderly subjects which can result in different cancers...Read more
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Potentiation of mitomycin C-induced apoptosis by lithium chloride in MDA-MB-231 breast cancer cells
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the principle cause of cancer mortality in females. Mitomycin C (MMC), as a potent antitumor drug, is u...Read more
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Anti-clostridial role of probiotics in prevention and treatment of Clostridium difficile infections
Microbiology and Infectious DiseasesPatients with varied conditions, such as Antibacterial therapy, Cancer chemotherapy, and gastrointestinal surgery are at...Read more
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Skin anti-ageing potential of Lactobacilli exopolysaccharides (EPSs) on human fibroblast
BeautySkin aging is a complex biological process influenced by a combination of endogenous or intrinsic and exogenous or extri...Read more
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Prevalence of beta-lactam resistant isolates of Enterobacteriaceae in clinical specimens
Microbiology and Infectious DiseasesBackground: The emergence of extended-spectrum beta-lactamase (ESBL) producing isolates of Enterobacteriaceae has impor...Read more
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Constructing a Novel Hypoxia-Inducible Bidirectional shRNA Expression Vector for Simultaneous Genes Silencing in Colorectal Cancer Gene Therapy
Cancer; Prevention, Diagnosis and TreatmentBackground: RNA interference (RNAi) is an efficient genetic approach in gene-specific knockdown and gene therapy; howeve...Read more
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Computational analysis and design of crRNA for post transcriptional regulation of metastamiR-10b and metastamiR-126 by CRISPR-C2C2 technique.
Medical GeneticsOne of the important causes of death in cancer patients is metastasis. Recently have been shown that specific group of m...Read more
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Association study of rs369770942 of neuregulin1 gene 3'UTR with schizophrenia
Medical Genetics: Schizophrenia is a mental disorder and affects approximately 1% of global population. This study suggests that rs36977...Read more
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Designing a Multiplex PCR for Amplification of STR markers linked to DFNB21
Medical GeneticsHearing loss is one of the most common birth defects which can affect about 2 to 3 out of every 1,000 babies born. So fa...Read more
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Targeted killer gene therapy of breast cancer cells using Pseudomonas exotoxin A
Cancer; Prevention, Diagnosis and TreatmentTargeted expression of killer genes in tumor cells ensures specific elimination of cancer cells with minimal effect on n...Read more
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Study of PAX5 gene expression in patients with gastric cancer
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is one of the biggest health problems in the world. Due to the lack of many carcinogenic biomarkers and t...Read more
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The role of oils in breast cancer in women (systematic review)
Cancer; Prevention, Diagnosis and TreatmentAbout one-third of cancers may be related to diet, along with lifestyle and physical activity. International data show t...Read more
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Classification of Genes Related to Infectious Disease: New Hybrid Method for High Imbalanced Data Sets
Medical GeneticsGene functionality explorations has a great importance in health science research. Developing gene classifiers having ac...Read more
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Investigation of mutations and polymorphisms in exon 11, 12, 22 and 23 in Non Caucasian cystic fibrosis patients from the north of Iran
Medical GeneticsCystic fibrosis (CF) is the most common autosomal recessive disease in Caucasians, caused by mutation in cystic fibrosi...Read more
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Berberine induced apoptosis of HT-29 cells through mediating of miR-21
Cancer; Prevention, Diagnosis and TreatmentBerberine is an isoquinoline that can be extracted from many medicinal herbs. microRNAs (miRNAs) are small non-coding RN...Read more
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In silico evaluation of anti-retroviral effects of lactoferrin from different species
Microbiology and Infectious DiseasesLactoferrin (LF) is an iron binding glycoprotein that is present in body fluids and mucosal secretions. Antimicrobial pr...Read more
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NRG1 expression changes in Autism spectrum disorder and play role in executive functions abnormalities
Medical GeneticsAutism spectrum disorder (ASD) is a pediatric heterogeneous psychiatric and neurodevelopment disorder with social and co...Read more
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Protective effect of silymarin on plasma membrane and DNA integrity of human sperm treated with cadmium chloride
Women and Reproductive HealthCadmium, as an environmental pollutant, exerts its destructive effects on male reproductive system and sperm by inducing...Read more
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Determination of GPR55 overexpression by quantitative real-time PCR as a biomarker for skin SCC detection
Cancer; Prevention, Diagnosis and TreatmentChronic wounds resemble the wounds arising with skin squamous cell carcinoma (SCC). Since they are cancerous, they shoul...Read more
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Cell-Penetrating Peptides and Tumor Targeting Peptides: achievements and challenges in application for cancer treatment
Cancer; Prevention, Diagnosis and TreatmentDespite significant advancement in the anti-cancer drugs recently, cancer still remains one of the leading causes of dea...Read more
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3D Graphene Framework: A High-Performance Adsorbent for Antibiotics
Nutrition and HealthAntibiotics have been considered as emerging pollutants due to their continuous input and persistence in the aquatic eco...Read more
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A foundation for universal T-cell based adoptive immunotherapy
Cancer; Prevention, Diagnosis and TreatmentThe patient-specific autologous therapy could be a significant limiting factor in the large-scale exploitation of CAR te...Read more
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Effect of EMF on Semen TBARS Concentration
Women and Reproductive HealthElectrical instruments in human life by development of applications causes new biological phenomenon in this century. Ne...Read more
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Evaluation of the effects of fish oil-derived Eicosapentaenoic acid on the proliferation of colorectal cancer cell line (hct116)
Cancer; Prevention, Diagnosis and Treatmentof these studies have indicated that Eicosapentaenoic acid (EPA) can induce apoptosis and reduce proliferation in cancer...Read more
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The Expression Profile of ERBB3 and Its Ligand NRG1 on Depressed Patients Investigation in Hormozgan
Medical GeneticsMajor depressive disorder (MDD), also known simply as depression, is a mental disorder characterized can negatively affe...Read more
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Study of gene expression and promoter methylation pattern of AKAP4 as possible breast cancer diagnostic marker candidate
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is an important health issue for millions of women around the world. Recently, a new group of tumor-associ...Read more
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Neural System Biomarkers
Stem cell and Medical ApplicationsBiomarkers are widely used by physicians, Labradoreans, and scientists. Popular utilization of biomarkers in vivo and in...Read more
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Anti-Diabetic Effects of Methanolic Extract of Calendula officinalis through Increased Antioxidant Enzymes Activity
Metabolism and Metabolic DiseasesDiabetes is a big challenge in the health care system. ROS generation is the major mechanisms which is involved in the p...Read more
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Fertilization rate would be improved after vitrification of immature mouse oocytes
Women and Reproductive HealthVitrification of oocyte is a promising technique to preserve fertility in different species, but it has deleterious effe...Read more
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Therapeutic effect of Human Tumor Necrosis Factor Receptor-2 on collagen -induced arthritis in Balb/c mice
Metabolism and Metabolic DiseasesRheumatoid arthritis (RA) is a chronic, systemic, immune-mediated inflammatory disease associated with decreased life ex...Read more
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the relationship between hypertension and advanced glycation end products
Nutrition and HealthElevated blood pressure is still one of the major risk factors for diseases and disabilities and also a public heath cha...Read more
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COMPARATIVE STUDY OF OLERACEIN E AND OLERACEIN L EFFECTS ON ANTI OXIDANT ACTIVITY, ANTI DIABETIC INDICATORS AND DAMAGE BIOMARKERS LEVELS IN PANCREATIC CELL LINE
Nutrition and HealthThe medicinal plants have valuable biochemical effects. The aim of this study was to assess the effects of Oleracein E a...Read more
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The effects of methanolic soy extract on ovary tissue modification in model of polycystic ovary syndrome as an inflammation state
Women and Reproductive HealthIntroduction and Objective: Chronic low-grade subclinical inflammation has been increasingly recognized as an interposer...Read more
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Optimization of the best concentration of Aloe vera extract for treating gastric cancer cells in order to reduce HER-2 gene expression
Cancer; Prevention, Diagnosis and TreatmentHER2 is a glycoprotein that has tyrosine kinase activity and plays an important role in guiding growth signals. Its expr...Read more
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Infections Associated with Bacterial Biofilms and Treatment Problems
Microbiology and Infectious DiseasesMicrobial biofilms are seen in 65% of human infections. Bacteria in biofilms society are resistant against antibiotics. ...Read more
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In silico epitope prediction and modeling for agent of smallpox and molecular docking for epitope-MHCⅠ receptor
Medical GeneticsAlthough Variola and Vaccinia viruses have been Eradicated but still smallpox can be a serious problem for Societies. H3...Read more
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Using micronuclei assay in cancer treatment
Medical GeneticsCancer is one of the leading causes of illness and mortality worldwide, after cardiovascular disease. There are differen...Read more
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The impact of miR-16 and miR-34a overexpression on the migratory and invasive potential of breast cancer cells
Cancer; Prevention, Diagnosis and TreatmentBreast cancer (BC) is the most frequent type of cancer and a main cause of cancer-related deaths among women worldwide. ...Read more
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Anti-cancer effect of redroot pigweed as weed plant species
Cancer; Prevention, Diagnosis and TreatmentLeukemia cancer is currently one of the major causes of cancer-related deaths among humans. Extracts of plants including...Read more
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Effect of different Electromagnetic fields (EMF) on sperm viability and motility
Women and Reproductive HealthToday, due to the advancement of the level of technology, electromagnetic fields (EMS) from various industries affect...Read more
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Study of DNA methylation pattern in sf-1 gene promoter region in endometriosis tissue samples of women in north west of Iran
Medical GeneticsEndometriosis is an estrogen-dependent inflammatory disease. Its defining feature is the presence of endometrium-like ti...Read more
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Investigation of toxicity effect of 4-Mepgc and 4-No2pgc on the K562 cell line (chronic myeloid leukaemia)
Cancer; Prevention, Diagnosis and TreatmentLeukemia is a particular type of cancer characterized by the failure of cell death or disability in the differentiation ...Read more
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Easy and efficient purification of flagellin from salmonella typhimurium ATCC 14028 without necessity of ultracentrifugation
Microbiology and Infectious DiseasesGram negative bacteria's Flagellin has many applications in diagnosis, treatment and vaccines. fliC, the major protein o...Read more
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Overexpression of cancer stem cell protein, Piwil2, promotes the expression of anti-apoptotic and proliferative genes in the gastric cancer cell line MKN-45
Cancer; Prevention, Diagnosis and TreatmentPiwi-like RNA-mediated gene silencing 2 (Piwil2) is an oncogene that is highly expressed in different tumors including ...Read more
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MUC21 as a suitable candidate for immunotoxins development for targeting esophageal cancer
Cancer; Prevention, Diagnosis and TreatmentEsophageal cancer is the world's eighth most common cancer and the sixth most common cause of cancer death in the world....Read more
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Comparison of miR-605 expression in normal and tumor tissue samples of patients with colorectal cancer.
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer (CRC) is the third common type of cancer, and is considered as the main cause of cancer deaths in both...Read more
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Investigation the effect of low intensity pulsed ultrasound (LIPUS) on proliferation of G 292 osteosarcoma cells on 3D porous PLGA/β-TCP scaffold within perfusion bioreactor
Stem cell and Medical ApplicationsInvestigation the effect of low intensity pulsed ultrasound (LIPUS) on proliferation of G 292 osteosarcoma cells on 3D p...Read more
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Investigation of deaths caused by cancer in Bandar Anzali in 2014
Cancer; Prevention, Diagnosis and TreatmentCancer is one of the main causes of death and disability in Iran and the world. This study was conducted to evaluate the...Read more
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Lipase adsorbtion on the single layer geraphene oxide dependes on pH and temperature
Nano-Biotech Medicalgraphene oxide (GO) has been used as a matrix for lipase immobilization. GO chemical properties are reported beneficial ...Read more
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Evaluation and comparison of digestion in two traditional and contemporary medicine schools And its effect on the treatment of diseases
Nutrition and HealthIn traditional medicine, one of the three most important nutritional principles is digestion. In our digestion, we deal ...Read more
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Apoptotic Effect of Tamoxifen on Hepatocellular Carcinoma Hep G2 Cell Line
Cancer; Prevention, Diagnosis and TreatmentHepatocellular carcinoma (HCC) is the sixth most common cancer, and the third most common cause of cancer-related death...Read more
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Design, synthesis and application of conjugated gold nanoparticles in photodynamic therapy
Nano-Biotech MedicalPhotodynamic therapy (PDT) has been developed as a novel method for cancer therapy. PDT involves the combined use of a p...Read more
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rDKK1 production and purification as an antigen
Cancer; Prevention, Diagnosis and TreatmentA critical goal in prevention and control of cancer is early detection of cancer. It is suggested that the Dickkopf1 (DK...Read more
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study of microbial quality of some food samples
Nutrition and Healthbacterias are considered as the most important factor to cause infection and food poisoning ,so that microbial contamina...Read more
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Investigating the toxicity of PEGylated Gold Nanoparticles and red LED light on Ecoli bacteria
Nano-Biotech MedicalToday, the emergence and spread of antibiotic-resistant strains of bacteria have become a major challenge to public heal...Read more
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Finding a new approach for Treatment of osteoporosis with trace element and antioxidant in rat animal model
Metabolism and Metabolic DiseasesOne of the most common bone metabolic and endocrinal disorders is osteoporosis. It is defined by progressive bone loss, ...Read more
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Induction of apoptosis by silibinin in SKBR3 breast cancer cell line through activation of caspase 3/7
Cancer; Prevention, Diagnosis and TreatmentThe poor prognosis of breast cancer is due to its resistance to the conventional treatments. Therefore, researchers are ...Read more
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Relationship between Hypertension in the First Trimester of Pregnancy with Weight and Height at Birth
Women and Reproductive HealthBackground: Hypertensive disorders with a prevalence of %5-10 are among the main causes of morbidity and mortality in mo...Read more
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Assessment of Tuberculous arthritis using molecular technique
Microbiology and Infectious DiseasesBacterial arthritis is one of the arthritis diseases known that can rapidly cause joint damage. Among the bacteria caus...Read more
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Design and evaluation of a colorimetric method for rapid determination of minimal inhibitory concentration of the bacteria belonging to Enterobacteriace
Microbiology and Infectious DiseasesIsolation of antibiotic resistant pathogenic bacteria in clinic may pose the serious problems. So a rapid method capabl...Read more
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Investigating the role of Nanodrugs in the treatment of Candida and Aspergillus infectons
Microbiology and Infectious DiseasesInvasive fungal infections are a major problem for immunocompromised patients in intensive care units. Morbidity and m...Read more
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HETEROGENEITY OF ESCHERICHIA COLI ISOLATES WITHIN DIFFERENT
Microbiology and Infectious DiseasesAim:Escherichia coli is one of the most important bacterial pathogens causing urinary tract infections (UTIs) . This bac...Read more
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Comparison of Antibacterial Activity of Essential Oil of Varieties of Calendula Plant from Varamin (Iran) on Escherichia coli and Staphylococcus aureus
Microbiology and Infectious DiseasesUncontrolled use of conventional antibiotics and synthetic antibacterial medicine has led to the proliferation of microb...Read more
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Evaluation of the HLA-B07 Allelic frequency in the patients with spondyloarthritis syndrome in zanjan province
Medical GeneticsIn 1974 Moll and colleagues established the concept of a group of inter-related disorders originally termed seronegative...Read more
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Investigation of Interleukin-17 gene polymorphism in patients with gasteric carcinoma and comparsion with healthy individuals reffered parison to the healthy control in Golestan Province 's hospitals.
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is one of the most common types of human cancers globally, which remains an important public health burde...Read more
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Antimicrobial effects of new designed 2-amino-tetrahydro-4H-chromene-3-carbonithril derivatives against some pathogenic microbial strains
Microbiology and Infectious DiseasesChromenes are natural compounds which also called benzopyrane derivatives and chromene-4-one and had several biological ...Read more
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Optical, structural and antibacterial properties assessment of ZnO:Mn nanoparticles
Nano-Biotech Medicalwith the rapid development of human life, controlling the harmful impacts of microorganisms is essential. The current st...Read more
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Gankyrin expression in ovarian cancer and its correlation with clinicopathological parameters
Cancer; Prevention, Diagnosis and TreatmentGankyrin (p28GANK) is a novel oncoprotein which regulates the phosphorylation of retinoblastoma protein (pRb) and degrad...Read more
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Silibinin Inhibits miR-17 in Co-cultured HUVECs with A549 Cell Line
Cancer; Prevention, Diagnosis and TreatmentMicroRNAs are involved in different biological processes including cell proliferation and apoptosis, the two intimately ...Read more
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CLONING AND EXPRESSION OF an antibody fragment (scFv) against PcrV protein of Pseudomonas aeruginosa in fed-batch cultivation mode
Microbiology and Infectious DiseasesPseudomonas aeruginosa is a major cause of hospital-acquired infections, particularly in mechanically ventilated patient...Read more
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Sensitivity of levofloxacin in combination with ampicillin-sulbactam and tigecycline against multidrug-resistant Acinetobacter baumannii
Microbiology and Infectious DiseasesDuring the last decades, emergence of antibiotic resistance among A. baumannii has been considered as a worldwide alarm....Read more
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Effect of Zinc nanoparticle on p53 expression in K562 cell line by Real Time PCR
Medical GeneticsChronic myeloid leukemia is a cancer of blood which is identified by bcr/abl translocation. Imatinib is a tyrosine kinas...Read more
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Apoptotic effect of anticancer drug Alimta on A549 calls is independent of HMGB1 release
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the leading cause of cancer-related deaths worldwide. Alimta is a new-generation antifolate drug, approv...Read more
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Survey of beta-lactam hydrolyzing enzymes in Pseudomonas spp. isolated from hospital sewage
Microbiology and Infectious DiseasesBackground: Beta- lactams are the largest group of antibiotics used by hospitals to treat infections caused by Gram-nega...Read more
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Investigating the role of exon7 axin2 in colorectal cancer (Laboratory and bioinformatics studies)
Cancer; Prevention, Diagnosis and TreatmentIn Iran, colon cancer is the third most common cancer. WNT pathway changes are commonly reported in this cancer. Among t...Read more
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the review of The implications in toxicity Metabolomics of Delta9-tetrahydrocannabinol
Metabolism and Metabolic DiseasesThe plant Cannabis sativa has been used for the effects of its psychoactive resins that name is (cannabinoid δ-9-tetrah...Read more
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Investigation of microRNAs involved in the EGFR molecular pathway as a biomarker in early detection of colorectal cancer
Medical GeneticsColorectal cancer (CRC) is one of the most common cancers in the world. The highest incidence of CRC in Europe, North Am...Read more
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Frequency of TET Resistance Gene and TEM Beta-Lactamase Resistance Genes in the Normal Flora of the Intestines of Addicted People Without symptoms of Intestinal Infection and Diarrhea, IRAN-Ahvaz City
Microbiology and Infectious DiseasesWide studies in National Institute for Drug Abuse(USA) are done with preventive goals, or risk and protective factors as...Read more
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The effect of manual acupuncture on anthropometric parameters in obese and overweight patients
Nutrition and HealthObesity is a chronic disease which is on the increase. Treatments of obesity include diet therapy, exercise, behavior th...Read more
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Gene expression profiling of the 8q22-24 position in human breast cancer: TSPYL5, MTDH, ATAD2 and CCNE2 genes are implicated in oncogenesis, while WISP1 and EXT1 genes may predict a risk of metastasis
Cancer; Prevention, Diagnosis and TreatmentGene expression profiling has been suggested to predict breast cancer outcome. The prognostic value of the 8q22 24 posit...Read more
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Synergistic Antibacterial Activity of Zinc Oxide Nanoparticles with Cuminum cyminum L. Essential Oil against the Food-Borne Pathogens Salmonella enterica
Nano-Biotech MedicalOne of the ways to control of pathogenic microorganisms in foods is to use preservatives and antimicrobial agents. Diffe...Read more
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The role of nutrition in gestational diabetes
Women and Reproductive HealthGestational diabetes is a condition in which blood glucose levels are rising during pregnancy and diabetes symptoms in a...Read more
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Overview the Challenges and Development of regenerative medicine in future
Stem cell and Medical ApplicationsMore than 2000clinical trials relating stem cells, there is not a single clinical difficult that is regularly treated wi...Read more
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Improvement of Prognostic model for breast cancer recurrence by data mining methods
Cancer; Prevention, Diagnosis and TreatmentIn Iran, every year 10,000 people suffer from breast cancer, of which half of them are under the age of 50. The recurren...Read more
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Curcumin regulates proinflammatory signaling function of thrombin in endothelial cells
Microbiology and Infectious DiseasesCurcumin regulates proinflammatory signaling function of thrombin in endothelial cells...Read more
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Evaluation of nitrosative stress in sprayer workers
Metabolism and Metabolic DiseasesAgricultural pesticides have an important impact on human health and farmers are people who are more exposed to pesticid...Read more
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Design and expression of an immunogenic construct based on calcium sensing receptor antigen
Cancer; Prevention, Diagnosis and TreatmentDue to texture and small size, identifying the parathyroid from thyroid glands is a very difficult procedure. They shoul...Read more
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Evaluation and comparison of digestion in two traditional and contemporary medicine schools And its effect on the treatment of diseases
Nutrition and HealthProper nutrition is one of the principles of "preserving health" in traditional and contemporary medicine. Wha...Read more
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Study of Effects of Crushed PLGA Nano-fiber Percentage on The Cell Proliferation in Chitosan-Gelatin-βGlycerophosphate Cartilage Scaffold
Nano-Biotech MedicalArticular cartilage has poor reparative capabilities. So Osteoarthritis is widespread globally in almost 70% of people o...Read more
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Determination Of intestinal Escherichia coli Pathotypes Frequency in Tehran Province By PCR
Microbiology and Infectious DiseasesEscherichia coli (E.coli) is an important member of the normal intestinal microflora for mammals, including humans.Diarr...Read more
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Modeling premunition for parasites
Microbiology and Infectious Diseases: Here we are interested in premunition that is an immunologic response in host which provides protection toward some pa...Read more
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Association of selenoprotein S expression and its variants with metabolic syndrome in subjects with cardiovascular disease
Metabolism and Metabolic DiseasesSelenoproteins S (SELS or VIMP) may regulate cytokine production, and thus play a key role in the control of the inflamm...Read more
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Down regulation of Bcl2 and up regulation of Bax during 2-NDC mediated apoptosis in Acute Promyelocytic Leukemia NB4 cells
Cancer; Prevention, Diagnosis and TreatmentDithiocarbamates have been known as important chemical synthetic compounds for treatment of cancer....Read more
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Effects of Rosmarinic acid on oxidative stress and total antioxidant capacity in vivo study
Metabolism and Metabolic DiseasesDiabetic disease is characterized by chronic hyperglycaemia. Numerous studies have shown that in diabetes mellitus, ther...Read more
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Impact of GSTP1 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia
Cancer; Prevention, Diagnosis and TreatmentGenetic variation influencing individual susceptibility to chemical carcinogens is one of the main factors leading to ca...Read more
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Snake venom: an anticancer agent in immunotoxin therapy
Cancer; Prevention, Diagnosis and TreatmentCancer is the second leading cause of death worldwide. Therefore, many studies are underway to innovate more efficient t...Read more
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Marine Biotechnology in public health and food safety
Nutrition and HealthSea and oceans make up more than 70 percent of the Earth's surface, and on the other hand, more than 80 percent of livin...Read more
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Frequency and Pattern of Resistance of AmpC-Beta-lactamase gene in Clinical isolates of Klebsiella pneumoniae from Zahedan Educational Hospitals
Microbiology and Infectious DiseasesThe detection of CTX-M-15 genes in ESBLs produced by Klebsiella pneumoniae strains provides useful information on epidem...Read more
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Detecting of herpes simplex virus’s DNA in the breast tumor, using polymerase chain reaction technique
Medical GeneticsIt has been proven that cancer cells formation can be due to the herpes simplex virus infection in human beings. The ai...Read more
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Analysis of hypermethylation of NFK-B ،TRAF1 and TRAF2 genes in patients with oral squamous cell carcinoma
Medical GeneticsCancer is a fatal disease caused mainly by environmental factors that mutate genes encoding critical cell-regulatory pr...Read more
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Alterations of gyrA in Enterobacteriaceae isolated of urinary tract infection resistance to quinolones antibiotics
Microbiology and Infectious DiseasesUrinary tract infection is one of the most common infections, which if not treated, it can be cause seriouse problem in ...Read more
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The effect of ziziphora extract on the expression of the Claudin_1 gene in the AGS cell line
Cancer; Prevention, Diagnosis and TreatmentClaudins are the main structural and functional proteins of tight junctions in epithelial cells. The altered expression ...Read more
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Performing PGD combined with HLA typing on more than 100 blastomeres
Medical GeneticsPreimplantation genetic diagnosis (PGD) is an option for carrier couples who want to assure their child’s health regar...Read more
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Blood porphyrin fluorescence peaks and its diagnostic value for early colorectal cancer (CRC) detection
Cancer; Prevention, Diagnosis and TreatmentPorphyrins are precursors of Heme metabolism. Any metabolic disorder like cancer can highly affect their level. Since th...Read more
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Purification of poly ribosylribotil phosphate capsule from Heamophilus influenza type- b strain ATF2 cultivated in bioreactor
Microbiology and Infectious DiseasesHaemophilus influenzae is a small gram negative cocobacilli non motile and can be seen as pleomorphic. H.inf.can cause ...Read more
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Investigation of CYP21A2 gene variants in Iranian patients with congenital adrenal hyperplasia
Medical GeneticsCongenital adrenal hyperplasia (CAH) is an autosomal recessive disease characterized by impaired adrenal steroidogenesis...Read more
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Matrix metalloprotease-9 (MMP-9) and premature myocardial infarction: A systematic review and meta-analysis
Medical GeneticsCurrent findings on the role of Matrix metalloproteases (MMPs) in cardiac remodelling and the outcome after acute premat...Read more
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Investigating the effects of saffron and melatonin with radiotherapy on viability of Hela cells
Cancer; Prevention, Diagnosis and TreatmentCancer is one of the biggest threats to human life. None of cancer treatment have not succeeded completely. One of the n...Read more
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Investigating th expression of E-cadherin gen among patients suffering from stomach cancer in West Azerbaijan province
Medical GeneticsGastritis Cancer is one of the general death causes of cancer all over the world. According to the results of the resea...Read more
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Studying the relation of blood lead level with the thyroid hormones and blood factors
Metabolism and Metabolic DiseasesLead has many applications in the industry but does not play a specific physiological role in the body. According to per...Read more
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Effect of hemodialysis on antioxidant enzyme levels in non- diabetic dialysis patients
Metabolism and Metabolic DiseasesDialysis patients are at a high risk for oxidative stress, resulting in an imbalance between the formation of free radic...Read more
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The latest developments in pharmaceutical biotechnology
Nano-Biotech MedicalBackground and Aim: Biotechnology has produced over 200 types of drugs and new vaccines that include products for the tr...Read more
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Normal body mass index as a protective factor for osteoporosis after menopause
Nutrition and HealthIncreased body weight is positively related to higher bone mineral density (BMD) in both pre- and post-menopausal women....Read more
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The Effect of Educational Intervention on Metabolic Control of Diabetic Patients Referring to the Diabetes Clinic of Shahid Bahonar Hospital in Karaj
Metabolism and Metabolic DiseasesIntroduction: The results of studies on complications and control of diabetes have clearly shown that good metabolic con...Read more
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Effect of Crocin on mitochondrial biogenesis and Oxidative stress in the Striatum of Cholestatic rats
Medical GeneticsOxidative Stress and increment of Mitochondrial Reactive Oxygen Species (ROS) production that occurs in cholestasis whic...Read more
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Investigating the absorption of anti-cancer drugs on the surface of the boron nitride nano cage by the dense function theory
Nano-Biotech Medicalmagesterol is a drug used in the treatment of breast and endometrial cancer. Due to the unwanted side effects of this dr...Read more
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A genetic variant in Multiple drug resistance gene is associated with poor prognosis of patients with esophageal squamous cell carcinoma
Cancer; Prevention, Diagnosis and TreatmentEsophageal squamous cell carcinoma (ESCC) is one of the causes of death from cancer. Several genetic variants in the 7q2...Read more
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Prevalence of gastric cancer in the patients undergoing bariatric surgery
Cancer; Prevention, Diagnosis and TreatmentIntroduction and goal: The number of obese people has grown up to 1.9 billion worldwide, that a large number of complica...Read more
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Distribution of Main Variants in Reactions of Cytotoxin vacA of H. pylori in Gastric Biopsy Specimens
Microbiology and Infectious DiseasesHumans have suffered digestive problems for centuries, and we now know that H. pylori are one of their most important ca...Read more
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Study of properties of Juglans regia plant on women’s health
Women and Reproductive HealthJuglans regia plant is one of Iranian native plants that some of it’s productive types are in Markazi province. The b...Read more
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The association of the H19 rs217727 polymorphism and Preeclampsia
Medical GeneticsPre-eclampsia is a pregnancy specific disorder; which is defined as pregnancy-induced hypertension and proteinuria. H19 ...Read more
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Identification of bacterial agents of urinary tract infection in patients referred to a laboratory during six months
Microbiology and Infectious DiseasesEstablishing a diagnosis of symptomatic UTI requires a patient to have symptoms and signs of a UTI and laboratory tests ...Read more
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Association of Cytochrome P450 2C19 (CYP2C19) gene polymorphism and the risk of endometriosis in Iranian population
Women and Reproductive HealthEndometriosis is a chronic disease that is characterized by the occurrence of endometrial glands and stroma outside the ...Read more
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Tamoxifen-induced rapid death of GPER positive cell lines by modulating RAS/MAPK signaling pathway
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the most common cancer in women worldwide. Tamoxifen is a nonsteroidal selective estrogen receptor modu...Read more
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Design, modeling and simulation of a novel immunotoxin structure affective against gastrointestinal malignancies
Cancer; Prevention, Diagnosis and TreatmentGastrointestinal malignancies comprise a remarkable proportion of cancer deaths each year. Although many drugs have been...Read more
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Investigating the expression alteration of long non-coding RNA GNAS-AS1 of breast cancer specimen
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the most common cancer in women, and due to high rates of invasion and metastasis in these patients, th...Read more
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Dendrosomal curcumin nanoformulation modulate apoptosis-related genes and protein expression in hepatocarcinoma cell lines.
Nano-Biotech MedicalIntroduction: The side-effects observed in conventional therapies have made them unpromising in curing Hepatocellular c...Read more
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Relationship of pre-body mass index with umbilical coiling index in gestational diabetes and non-gestational diabetes mellitus.
Metabolism and Metabolic DiseasesIt has been well documented that overweight or obesity before pregnancy is a strong predictor of gestational diabetes me...Read more
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Evaluating the genetic variations in functional domains coding regions of MSMB in infertile men with unexplained infertility
Medical GeneticsΒ-Microseminoprotein(MSMB) is one of the most abundant proteins in human seminal plasma. This protein binds to head and...Read more
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LPS Effects on induction of regulatory T cells in peripheral blood mononuclear cells in endometriosis patients
Women and Reproductive HealthEndometriosis is an estrogen-dependent chronic inflammatory disease affecting women in reproductive ages. Regulatory T c...Read more
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Evaluation of the effect of saturated and unsaturated fatty acids on the growth and production of outer membrane vesicles in human gut microbiota
Microbiology and Infectious DiseasesA diverse and complex symbiotic microbial community colonize in human host,espicially in the gastrointestinal tract,refe...Read more
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Electrospun PVA/PVP/chitosan Membrane with Controlled Release of Antibiotics for intraperiodontal pocket drug delivery
Nano-Biotech MedicalGingivitis and periodontitis have become major public health problem in the world. Such growing incidence of periodontit...Read more
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Evaluation of toxicity of functionalized graphene with ginsenoside Rh2, Lysine and Arginine on RBCs, blood coagulation and cardiovascular tissue: In vitro and In vivo study
Nano-Biotech MedicalIn this study, blood and cardiotoxicity of functionalized graphene with ginsenoside Rh2 (Rh2), Lysine and Arginine was e...Read more
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Investigating the relationship between metacognitive beliefs, and premenstrual syndrome and depression caused by that, in female students studying at Tehran University of Medical Sciences
Women and Reproductive HealthThe purpose of this research was studying the relation between meta-cognitive beliefs on premenstrual syndrome and depre...Read more
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Evaluation of the interaction between hemoglobin protein and angiotensin-inhibitory peptide by three-dimensional fluorescence method in the absence and presence of low-frequency electromagnetic fields
Metabolism and Metabolic DiseasesMillion people in worldwide are suffering from high blood pressure and related diseases. Over the past two decades, ther...Read more
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Pregnancy management in Iranian Traditional Medicine
Women and Reproductive HealthManaging complications in pregnancy is so important cause of sensitive situation of the mother and the fetus. Physicians...Read more
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Cytotoxic activity of Berberine on the growth of breast cancer cell line (MCF-7)
Cancer; Prevention, Diagnosis and TreatmentMuch research has been conducted on the benefits of various phytochemicals in many herbs, fruits and vegetables and thei...Read more
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Sugar-sweetened beverages increase cardiovascular risk in diabetic patients
Nutrition and HealthSugar sweetened beverages (SSBs) are any type of sugar-added drinks like soft drink, syrup, etc. SSBs consumption has in...Read more
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Using case–control study to find a relationship between SLC11A1 gene and clinical mastitis
Medical GeneticsMastitis is a major source of economic loss in dairy herds. The objective of this research was to evaluate the associati...Read more
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Characterization of a carboxypeptidase inhibitor peptide isolated from Iranian scorpion venom glands cDNA library: a good candidate for cancer therapy
Cancer; Prevention, Diagnosis and TreatmentFinding a safe strategy for targeting tumor cells without affecting normal cells is one of the goals of cancer treatment...Read more
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Synthesis of pH-sensitive micelles based on F127-Dox conjugated for drug delivery to cancer cells
Nano-Biotech MedicalA variety of nano-systems constituted by polymer–drug conjugates have been designed to overcome its shortages on water...Read more
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Evaluation of circulating prognostic tumor marker DNA in the blood of brain tumor patients
Cancer; Prevention, Diagnosis and TreatmentRecent evidence suggests that tumor cells may release DNA into the circulation, which is enriched in the serum and plasm...Read more
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Anticancer Application of Camel Milk: A Review of Recent Research
Cancer; Prevention, Diagnosis and TreatmentBecause of importance of cancer and the side effects of existing therapies, it is essential to find new therapeutic stra...Read more
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Investigating the Relationship between Polymorphism of p22phox in Smoker Population with Chronic Obstructive Pulmonary Disease (COPD) and Susceptibility to Disease
Medical GeneticsCOPD (chronic obstructive pulmonary disease) is a slowly progressive condition characterized by airflow limitation, whic...Read more
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Biosynthesis of Tellurium nanoparticles by Streptomyces isolate B2.1369F
Nano-Biotech MedicalBiosynthesis of Tellurium nano particles (TNPs) has great advantage since it has no chemical contamination in the enviro...Read more
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Effect of Velcade in Combination with Nanocurcumin in Breast Cancer 4T1
Nano-Biotech Medical: It is well known that breast cancer has the highest incidence rates of about 30% of all types of cancer in women, and ...Read more
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An update review about stem cell therapy for diabetes mellitus
Stem cell and Medical ApplicationsMesenchymal stem cells (MSCs) are the most widely used stem cells of the human body because of successful isolation, and...Read more
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Comparison of chondrocyte cells survival in alginate and throat fibrin scaffolds using MTT assay for repair and treatment of cartilage
Stem cell and Medical ApplicationsArthritis or osteoarthritis is the most common disease that is counted as the category of arthritis in which the joint c...Read more
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Effect of intracerebroventricular injection of Adenosine on food and fat intake in neonatal chicks
Nutrition and HealthThe present article was aimed to clarify the role of central Adenosine on food intake in neonatal chicks. Adenosine is n...Read more
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Investigation of A New Paclitaxel Nano Niosomal formulation and Biological Evaluation of Entrapped Paclitaxel on breast cancer cell line
Nano-Biotech MedicalRegarding that the breast adenocarcinoma is the most widespread disease among women, paclitaxel, an anti-cancer drug, co...Read more
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The Role of Viral Proteins VP24 and VP35 in The Pathogenesis of The Ebola Virus
Microbiology and Infectious DiseasesThe Ebola virus is a member of the Filoviridae family, which is causing hemorrhagic and fatal fever to humans. Ebola is ...Read more
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Evaluation of NTT and Double-Test in screening of Down Syndrome
Women and Reproductive HealthPrenatal diagnosis of genetic, congenital and hereditary diseases is the first step to prevent and control these prob...Read more
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Molecular screening for E255K mutations in Imatinib Resistant-CML
Medical GeneticsChronic myelogenous leukemia (CML) is a clonal disease that kind of hematopoietic stem-cell cancer. A significant number...Read more
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Bioinformatics evaluation of hsa-miR-548g related to single nucleotide polymorphism (rs1803622) of GAPDH gene in patients suffering from breast cancer
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is one of the most prevailing cancer among females. GAPDH gene is located on chromosome l on position of G...Read more
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Correlation of umbilical coiling index and HbA1C in gestational diabetes mellitus (one-step strategy).
Metabolism and Metabolic DiseasesGestational diabetes mellitus [GDM] is a prevalent and potentially serious condition which may put mothers and fetuses a...Read more
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Molcular Detection of Mupirocin Resistance in Staphylococcus aureus
Microbiology and Infectious DiseasesStaphylococcus aureus has become the most common cause of hospital acquired infections over the last few decades. The ba...Read more
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The Approaches for Salivary Glands (SGs) Regeneration: a review
Stem cell and Medical ApplicationsSaliva is secreted from three pairs of major SGs and 100–800 minor SGs and plays a vital role in oral and general heal...Read more
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Enrichment analysis of hsa-miR-320b-1 most related pathways in cancer
Cancer; Prevention, Diagnosis and TreatmentIntroduction: Cancer is a complex disease in which the expression of the gene is unbalanced. MicroRNAs are a group of no...Read more
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Epigenetic Mechanisms as Therapeutic Targets
Medical GeneticsEpigenetics, in conjunction with genetic mechanisms, determine the biological fate of cells and living organisms. epig...Read more
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Production of protein A containing Thiol Group for binding to fluorescence dye To increase the sensitivity of antibody detection
Nano-Biotech Medicalstaphylococcal Protein A is a cell wall component which has the ability to bind to immunoglobulins of different animal s...Read more
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The role of cabergoline medicine in treating Cushing's syndrome: A systematic review
Metabolism and Metabolic DiseasesCushing's syndrome is an endocrine disorder caused by the excessive production of corticosteroid hormones and adrenocort...Read more
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Evaluation of H.pylori drug resistance to current cure in North-West of Iran
Microbiology and Infectious DiseasesAlmost half of the world population is infected with Helicobacter pylori, a major risk factor for chronic gastritis, pep...Read more
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Lack of association between Hypoxia Inducible Factor rs11549465 polymorphism and Preeclampsia
Medical GeneticsPre-eclampsia (PE) is an obstetric disorder that may result inmaternal and neonatal mortality and morbidity. Placental h...Read more
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evaluation of anti-mullerian hormone in daughters of women with polycystic ovary syndrome
Women and Reproductive HealthPolycystic Ovary Syndrome(pcos) is one of the most common endocrine diseases among women during their fertility years . ...Read more
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Investigation of C-582 A>G polymorphism at beta globin cluster gene in beta-thalassemia patients
Medical GeneticsThalassemia is the most prevalent monogenic disorder worldwide resulting from the inappropriate production of heme. pati...Read more
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Microencapsulation and double-coating of probiotic bacteria for enhancement of their viability and targeted delivery
Nutrition and HealthThe purpose of this study was to assess the protecting character of double coated beads of alginate-chitosan-Eudragit S1...Read more
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The effect of vinorelbine on HMG proteins in lung cancer A549 cells
Cancer; Prevention, Diagnosis and TreatmentVinorelbine is a semisynthetic vinca alkaloid antitumor drug, widely used in the treatment of cancers such as advanced n...Read more
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Detection of Mycoplasma arginini contamination in biological products by PCR
Microbiology and Infectious DiseasesIntroduction: Mycoplasmas are one of the most important pollutants in biological products and cell cultures, and are a...Read more
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A Turn-Off Fluorescent Sensor Based On Carbon Dots for Sensitive Detection of Tetracycline in Milk
Nutrition and HealthThe detection of tetracycline in animal-derived food and drug is very significant, because of its harmful effects on hum...Read more
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Evaluation of TCA cycle in patients with acute myeloid leukemia
Cancer; Prevention, Diagnosis and TreatmentAcute myeloid leukemia (AML) is the most type of acute leukemia in adults. In solid tumors, alteration of energy metabol...Read more
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Operational study of plastination as an alternate method for dissection
Nano-Biotech MedicalSince, two-thirds of the approved Zoology Laboratory syllables, defined by the Ministry of Science, Research and Technol...Read more
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Managing The Abnormal Papsmear In Pregnancy
Cancer; Prevention, Diagnosis and TreatmentCervical cancer is the most common malignancy diagnosed during pregnancy . The incidence of abnormal pap smear in pregna...Read more
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A review: Runt-related transcription factor 2 (RUNX2) and its signaling pathways in cardiovascular complications.
Metabolism and Metabolic DiseasesVascular calcification (VC) is a process similar to bone mineralization. VC has been observed in chronic kidney disease,...Read more
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Evaluation of Adenovirus in Pseudomonas aeruginosa susceptible keratitis by PCR molecular method
Microbiology and Infectious DiseasesKeratitis is inflammation of the cornea of the eye. In keratitis, microbial agents are important. In the presence of inf...Read more
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Cloning, expression and functional assay of bacterial Uricase, a medical enzyme for the treatment of chronic gout
Metabolism and Metabolic DiseasesUricase, which is originated from a variety of organisms including bacteria, is an important agent for tracing of Uric A...Read more
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Study on protein of leech saliva of Hirudo Oreintalis, Utevsky & Trontelj 2005 in different ages
Nutrition and HealthMedicinal leech, during feeding, enter in host body many bioactive substances that often contain proteins and peptides. ...Read more
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A study on the interaction of angiotensin I converting enzyme inhibitory peptide with human hemoglobin protein by conductometry method in the absence and presence of a low frequency electromagnetic fi
Metabolism and Metabolic DiseasesHigh blood pressure, or hypertension, is a chronic disease in which the blood pressure goes up. Angiotensin converting e...Read more
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Autism spectrum disorder (ASD) and cancer: both share same genes but different outcomes.
Medical GeneticsAutism spectrum disorder (ASD) is a neurodevelopmental disorder and it is characterized by social and communication prob...Read more
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NEW CONCEPTS IN THE IMMUNOPATHOGENESIS OF MULTIPLE SCLEROSIS
Medical GeneticsMultiple sclerosis (MS) is a chronic disorder of the central nervous system characterized by autoimmune inflammation, de...Read more
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ELISA Cross-Reactivity method to confirm recombinant fliC from salmonella typhimurium and evaluate impurities in purified recombinant protein
Microbiology and Infectious DiseasesRecombinant proteins as important materials for biomedicinal research, need high level of purity in order to be used in ...Read more
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In silico design and analysis of crRNA for post transcriptional regulation of oncogenic miR-128-2 and miR-217 by CRISPR-C2C2 technique.
Medical GeneticsBased on recent studies some microRNAs could have drug resistant effects in turmeric cells during therapy. There are evi...Read more
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Motor neuron differentiation potential of human umbilical cord blood- derived mesenchymal stem cells, in vitro
Stem cell and Medical ApplicationsMany people suffer from spinal cord injuries annually. These deficits usually threaten the quality of life of patients. ...Read more
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Inhibition of cell growth in HCT-116 human colorectal cancer cell line by sodium butyrate, a HDAC inhibitor
Cancer; Prevention, Diagnosis and TreatmentSodium butyrate (NaBu), a histone deacetylase (HDAC) inhibitor, is the byproduct of anaerobic microbial fermentation ins...Read more
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study of promoter methylation status of pax5 gene in patients with gastric cancer
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is the fifth leading cause of cancer and is also the third leading cause of death in the world .Although ...Read more
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Effect of Biochanin A on retinal angiogenesis and inflammation in STZ induced diabetic rats
Metabolism and Metabolic DiseasesWithout proper medication for the treatment of diabetic retinopathy (DR), retinal cells become malnourished and degenera...Read more
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microRNAs as potential biomarkers in early detection of Breast cancer
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is one of most worrisome health problems in women across the world. Its incidence and mortality have under...Read more
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An in vitro study on the cytotoxicity of anticancer drug Mitoxantrone on hematopoietic stem cells of bone marrow
Cancer; Prevention, Diagnosis and TreatmentMitoxantrone (Novantrone®; dihydroxyanthracenedione) is a synthetically designed antineoplastic agent and structurally ...Read more
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A Review of the Fungi Generating the Cellobiose Dehydrogenase Enzyme to Remove Bacterial Biofilms
Microbiology and Infectious DiseasesThe biofilm causes more than 60% of nosocomial infections and 65% human infections. Bacteria in biofilms society are res...Read more
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The effect of Rosa canina extract on Bax gene expression in gastric adenocarcinoma cell line(AGS)
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is the most common cancer in the world. It occurs as a result of many factor and there is massive invest...Read more
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Cytotoxic effect of anticancer drug 5-Azacitidine on hematopoietic stem cells of bone marrow in the presence and absence of Colony stimulating factors
Cancer; Prevention, Diagnosis and TreatmentThe cytosine analogue, 5-Azacitidine as a DNA methyltransferase inhibitor is currently considered the most advanced drug...Read more
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Investigation of synergies effects of albumin- amino penicillin on Staphylococcus aureus MRSA
Nano-Biotech Medicalduring the recent decades, Nanotechnology has entered the field of drug industries and importance of nano-drugs in curin...Read more
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Molecular identification of Aspergillus isolated from livestock feed and poultry using ASAP1 sequencing
Microbiology and Infectious DiseasesThe contamination of livestock feed and poultry with toxic fungi, such as aspergillus in the air and the environment, is...Read more
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Effect of DNA Demethylating Agent Genistein on Epigenetic-modifying Estrogen Receptor Alpha Gene Expression and Apoptosis Induction and also Cell Viability in Hepatocellular Carcinoma HepG 2 cell line
Cancer; Prevention, Diagnosis and TreatmentIn the normal mammalian cells, epigenetic changes such as DNA methylation and histone acetylation play an important role...Read more
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Green Synthesis of Tellurium nanoparticles by Streptomyces isolate BH8 isolated from soils of Sarcheshmeh Copper Complex, Kerman, Iran
Nano-Biotech MedicalTellurium nano particles (TNPs) have pharmaceutical, medical, industrial and environmental importance. Tellurium has als...Read more
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Anti-anxiety effects of sinapic acid in NMRI mice
Nutrition and HealthThe present study investigated the anxiolytic effects of sinapic acid on NMRI mice behavior in the elevated plus-maze (E...Read more
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Determination of antibiotic-resistant strains of isolated Brucella in Markazi Province
Microbiology and Infectious DiseasesBrucellosis is one of the common diseases of man and animals are caused by bacteria of the genus Brucella. The purpose o...Read more
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Reproductive Health Training Program on Students in IRAN: An Action Research Approach
Women and Reproductive HealthTransition from adolescence to adulthood is one of the important periods in the individual life. New behaviors are learn...Read more
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Client's Attitude Towards legal and Ethical Aspects of Sperm Donation in a Health Center of Tehran
Women and Reproductive HealthSperm donation is one of the technologies associated with infertility treatment. Some couples don't have any child due t...Read more
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Aloe Vera Herbal Effects on Diabetes Treatment and Prevention: A Systematic Review
Metabolism and Metabolic DiseasesDiabetes is one of the most common metabolic diseases that affects more than 150 million people in the world. It is the ...Read more
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Detection of macrolid and fluoroquinolones resistance among campylobacters isolated from diarrhea patients in Markazi province - 2015
Microbiology and Infectious DiseasesCampylobacter species, especially C. jejuni and C. coli, are the most common bacterial causes of gastroenteritis in huma...Read more
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Antibacterial effects of curcumin encapsulated in micelle nanoparticles on mexX gene expression in ciprofloxacin resistant isolates of Pseudomonas aeruginosa in Guilan
Nano-Biotech MedicalCurcumin, a polyphenolic compound fromturmeric (Curcuma longa) is a pharmacologically safe agent that has antibacterial ...Read more
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Frequency of TEM and SHV genes in the strains of Acinetobacter producing broad-spectrum isolated ß-lactamases from Zahedan patients by PCR method
Microbiology and Infectious DiseasesAcinetobacter baumannii is one of the most important factors in hospital infections, and its Colonization rate in hospit...Read more
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Comparative miR34a expression profile analysis in tumor and normal tissues of patients with colorectal cancer
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer is a type of prevalent cancers in populations and allocates numbers of mortality. Recently, researcher...Read more
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Association between Biochemical Markers BHCG in Screening First Trimester of Pregnancy in Women with PCOS
Women and Reproductive HealthPCOS (polycystic ovary syndrome) is a common endocrine system disease among women of reproductive age. Its prevalence in...Read more
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The effect of curcumin, zinc and N-acetylcysteine on the MMP9 expression
Metabolism and Metabolic DiseasesCardiovascular diseases (CVD) are mostly prevalent in the general population.Matrix metalloprotease 9 (MMP9) is a matrix...Read more
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Toxic effects of Selenite and need to bio removal of it
Nutrition and HealthSelenium is an important micronutrient for human and animal health, however it is toxic slightly above homeostatic requi...Read more
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Sun protection factor (SPF) determination of sericin cream and niosomal gel
BeautySericin is a protein extracted from silk and has antioxidant, antimicrobial, antineoplastic, wound healing and moisturiz...Read more
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Nephroprotective effect of Lavandula officinalis L. ethanolic extract in alloxan induced diabetic rats
Nutrition and HealthDiabetes mellitus (DM), a metabolic disorder is a major public health problem in both developed and developing countries...Read more
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T cell engineering for cancer imenuterapy
Cancer; Prevention, Diagnosis and TreatmentWith regard to the prevalence of cancer in the world, treatment have become important. One of the methods is to stimula...Read more
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Investigating the presence of chemical compounds in pineapple
Cancer; Prevention, Diagnosis and TreatmentPineapple is a member of the Ananasian family, it is a sub-tropical fruit. It has many chemical compounds that are impor...Read more
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Influence of CYP2D6 and CYP3A4 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia and treatment response
Cancer; Prevention, Diagnosis and TreatmentXenobiotic- metabolizing enzymes compose an important line of defence against a variety of carcinogenes and environmenta...Read more
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Fast detection of Pseudomonas aeruginosa keratitis by Polymerase Chain Reaction (PCR)
Microbiology and Infectious DiseasesPseudomonas aeruginosa is an opportunistic pathogen that has different virulence factors. This organism is commonly foun...Read more
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Identification of Oral strains of Lactobacillus.species in patients with chronic periodontitis and healthy individuals
Microbiology and Infectious DiseasesOral infections constitute some of the most common and costly forms of infections in humans.Chronic periodontitis has be...Read more
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Evaluation of nitrate and nitrite content in meat and meat products and their role of these substances in carcinogenesis
Cancer; Prevention, Diagnosis and TreatmentBecause of N-nitrous compounds formation in meat and meat products, There is a direct correlation between high consumpt...Read more
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Preconditioning of bone marrow-derived mesenchymal stem cells by AdipoRon potentiates cell migration ability, in vitro.
Stem cell and Medical ApplicationsMesenchymal stem cells (MSCs) have represented a great potential in recent stem cell-based therapies as well as regenera...Read more
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Phylogenetic and Bioinformatics analysis of Interferon beta-1 Protein
Medical GeneticsInterferon beta-1b protein is used to improve MS disease and reduce the number of attacks in patients. The purpose of th...Read more
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The relationship between TPH1 (rs1800532) and TPH2 (rs4570625) polymorphisms in type 1 bipolar patients compared with healthy subjects
Medical GeneticsBipolar disorder has episodes of depression and mania or hypomonia. several serotonin-associated genes correlated with S...Read more
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Ischemia-modified albumin as an oxidative stress biomarker in acute coronary syndrome
Metabolism and Metabolic DiseasesFree radicals increasing or Antioxidants decreasing may contribute to impair the equilibrium between oxidant and antioxi...Read more
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Silencing of TIM-3 expression by miR-326 affects apoptosis and proliferation of human HL-60 leukemia cell line
Cancer; Prevention, Diagnosis and TreatmentLeukemia Stem Cells (LSCs) are the main reason for drug-resistance and disease relapse in Acute Myeloid Leukemia (AML). ...Read more
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Endurance training resulted in significantly greater betatrophin responses compared with resistance training alone, and resistance and endurance exercises combined
Metabolism and Metabolic DiseasesBetatrophin, which recently identified, is a liver and adipose tissue produced hormones that regulates the level of lipi...Read more
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study of mesenchymal stem cell differentiation to chondrocyte on electrospun nanofibrous polyvinyl alcohol alginate sulfat blend
Stem cell and Medical ApplicationsCartilage tissue engineering is used as a potential solution for replacing or repairing damaged tissue. In this method, ...Read more
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SNP genotyping within INS, INSR, TCF7L2 and PPR- y genes associated with type 2 diabetes in India
Medical GeneticsA pilot population-based study was carried out to evaluate linkage between singlenucleotide polymorphisms within the kn...Read more
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Evaluation of PRC1 gene expression in gastric cancer patients
Cancer; Prevention, Diagnosis and Treatment: Cancer is one of the most important causes of death. Among cancers, gastric cancer is the fourth most common cancer an...Read more
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Investigating the effects of saffron and melatonin with radiotherapy on viability of Hela cells
Cancer; Prevention, Diagnosis and TreatmentNowadays, a lot of people in the worldwide dead because of cancer. Despite much research in this area, there is still no...Read more
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Food Patterns and Framingham Risk Score in Iranian Adults: Tehran Lipid and Glucose Study: 2005-2011
Nutrition and HealthHealthy dietary habits can prevent cardiovascular diseases (CVD). The aim of the present study was to investigate the as...Read more
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Association Chlamydia trachomatis infection and TNFα -308 polymorphism in abortion
Microbiology and Infectious DiseasesSeveral bacterial infections such as Chlamydia trachomatis and host genetic background, including TNFα SNP polymorphism...Read more
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Poly(A)-tail shortening Length: an Alternative Epigenetic Mechanism for Translational Control of Oncogenes
Medical Genetics: mRNA poly(A) tails in 3'UTR is important for its stability and translation. t is observed Poly(A) tails is dynamic and...Read more
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A genetic variant in CDKN2A/2B locus was associated with poor prognosis in patients with esophageal squamous cell carcinoma
Cancer; Prevention, Diagnosis and TreatmentEsophageal squamous cell carcinoma (ESCC) is among the leading causes of cancer related death. Despite extensive efforts...Read more
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Prevalence of Cysticercus bovis in Cattle slaughter-house in Piranshahr city, Iran (2011-2115))
Microbiology and Infectious DiseasesCysticercus bovis are the intermediate stage in the life cycle of a human tapeworm (Taenia saginata). Cysticercus bovis ...Read more
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Progress and Prospect of Nanotechnology in Stem Cells
Nano-Biotech MedicalThe apparition of nanotechnology has paved the way for an obvious understanding of stem cell therapy in vivo and by repe...Read more
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Effect of genistein associated with agonist (17-β estradiol) on the viability and apoptosis of human hepatocellular carcinoma HepG2 cell line
Cancer; Prevention, Diagnosis and TreatmentBackground: One of the most lethal cancers is Hepatocellular carcinoma (HCC). Genistein (GE) is a choice compound for tr...Read more
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Wound healing effect of Tea tree oil on Methicillin Resistant Staphylococcus aureus (MRSA) : an Animal Study
Microbiology and Infectious DiseasesTea tree oil (TTO), or melaleuca oil, is an essential oil with a fresh camphoraceous odor and a color that ranges from p...Read more
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Computer aide discrimination of the ovarian lesions by CT scan images
Cancer; Prevention, Diagnosis and TreatmentTo explore diagnostic potential of computerizing texture analysis (TA) methods in discrimination of the normal, benign...Read more
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Study of matrix metallo proteinase (MMP)-9 gene & its phylogeny tree as a critical gene in metastases
Medical GeneticsThere has been a clear connection between MMPs,ECM degradation & cancer cell invasion. Matrix metalloproteinase(MMP)-9, ...Read more
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The effects of nano-liposomes containing curcumin on the lung cancer cell line.
Nano-Biotech MedicalLung cancer is one of the most common and malignant cancer in both sexes. The prevalence and spread of cancer in iran an...Read more
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Knowledge and Practice of Breast Self-Examination Among Female Students in Sari Islamic Azad University in 2015-2016
Cancer; Prevention, Diagnosis and TreatmentBreast self-examination (BSE) is one of the ways of prevention and early detection of breast cancer. The aim of this stu...Read more
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In silico cancer therapy by using genome editing tool: CRISPR/Cas9
Cancer; Prevention, Diagnosis and TreatmentGiven the fact that cancer today has a broad spectrum of diseases in the populations, and also by relying on the fact th...Read more
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The comparative proteomic pattern study of albumin fraction in type I Gaucher Patients with 2 Dimensional Electrophoresis
Metabolism and Metabolic DiseasesThe gaucher disease is the most common type of lysosomal storage diseases that, particularly affects the macrophage cell...Read more
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Recombinant fibroin containing the RGD motif enhances limbal mesenchymal stromal cell adhesion and proliferation
Stem cell and Medical ApplicationsAt the periphery of the cornea, in a region called the limbus, exists a population of stromal progenitor cells termed li...Read more
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TYCSB culture media reliability for S. mutans isolation
Microbiology and Infectious DiseasesAlthough the clinical significance of dental caries is well recognized, the exact etiology of the condition is not under...Read more
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EXPRESSION OF AN ANTIBODY FRAGMENT (SCFV) AGAINST AMYLOID-BETA USING T7 PROMOTER IN FED-BATCH CULTIVATION MODE
Microbiology and Infectious DiseasesIn the current investigation, the expression yield and solubility of Aβ antibody was analyzed using T7 promoter in fed-...Read more
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Development of a chemiluminometric lateral flow biosensor for sensitive detection of Escherichia coli
Microbiology and Infectious DiseasesPaper based nucleic acid testing (NAT) has attracted significant interest in point of care diagnostic field. Lateral flo...Read more
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Identifying Linking Mechanisms of Allergy and Cancer
Cancer; Prevention, Diagnosis and TreatmentAllergy and cancer are prevalent diseases and cause a lot of morbidity and mortality. In recent years, many studies have...Read more
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Genes involved into both alternative splicing and aging pathways as biomarkers for Parkinson Disease diagnosis
Medical GeneticsParkinson's Disease is a degenerative movement disorder that exhibit symptoms through progressive loss of dopaminergic...Read more
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An investigation on the structure and function of the cell surface lung-specific antigens for development a new generation of immunotoxins
Cancer; Prevention, Diagnosis and TreatmentLung cancer, with common symptoms such as coughing, weight loss and shortness of breath, is a disease via uncontrolled g...Read more
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Interaction of Methotrexate on Stability and structure of Human Serum Albumin
Nano-Biotech MedicalHuman serum albumin(HSA) as the most abundant carrier protein in blood plasma has been widely studied. HSA is often used...Read more
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Molecular study of 92 fetal of couples with recurrent abortion in Mazandaran
Medical GeneticsChromosome abnormalities has recognized as a major factor contributing to pregnancy loss and accounted for about 50% of ...Read more
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Structural Study of Horseradish Peroxidase upon Interaction with Gold Nanoparticles
Nano-Biotech MedicalRemarkable advancements have been made in the field of nanotechnology, including design of hybrid systems of nanoparticl...Read more
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Blocking of vascular endothelial growth factor signaling through design of bi-specific single domain antibody
Nano-Biotech MedicalOver-expression of vascular endothelial growth factor (VEGF) leads to the proliferation and neovasculature of cancer cel...Read more
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Designing and cloning and expression of bean defensin in human embryonic kidney cells and evaluating their antibacterial function
Microbiology and Infectious DiseasesDefensins are among the most important cationic peptides that their presence in a wide range of herbs and animals has be...Read more
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The Possible Role of B. thetaiotaomicron-derived Outer Membrane Vesicles (OMVs) in the Modulation of Cholesterol Uptake and Diet-induced Obesity
Metabolism and Metabolic DiseasesAltered gut microbiota composition has been proven to be associated with several disorders including metabolic syndrome....Read more
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The effects of preconditioning mesanchymal stem cells with hydrogen peroxide and serum deprivation on cell viability and apoptosis.
Stem cell and Medical ApplicationsIt is known that application of mesenchymal stem cells is an effective treatment in many diseases. Despite of cell thera...Read more
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isolates from Kermanshah province submitted at National Animal tuberculosis reference Laboratory at Razi institute
Microbiology and Infectious DiseasesTuberculosis is a zoonotic which has long been recognized and is still one of the most life-threatening diseases. Tuberc...Read more
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The Bioinformatic prediction of selected miRNAs role in regulation of cell death pathways in Parkinson’s disease
Medical GeneticsParkinson's disease (PD) is the second most common neurodegenerative disease. Due to its unknown etiology and pathology,...Read more
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The Role of Nanobiotechnology in Identification and Treatment Lung Cancer
Nano-Biotech MedicalNanotechnology is the engineering of functional systems at the molecular scale. Therefore, it is possible to combine nan...Read more
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Review: ASD heritability
Medical GeneticsAutism Spectrum Disorder (ASD) is one of the most common neurodevelopmental disorders; due to its high occurrence rate a...Read more
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Investigating the Verification of the Personnel Hand Hygiene Dividedly among Five Situations in Intensive Working in Namazi Hospital of Shiraz
Microbiology and Infectious DiseasesHand hygiene behavior divides into two categories: the innate hand hygiene and the selective hand hygiene. The innate ha...Read more
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Role of Immune system in treatment of cerebral palsy by stem cells
Stem cell and Medical ApplicationsCerebral Palsy (CP) is known as a non-progressive brain disorder that occurs due to injuries or abnormalities in develop...Read more
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Production and evaluation of scFvs against HER2 antigen for breast cancer immunotherapy
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is common cause of women death in the world. There is ErBb2/HER2 in 25%-30% breast cancer cases. Trastuzu...Read more
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Investigating the Epidemiology of Concussed Patients, Hospitalized in Khatam al-Anbyia and Ali ibn Abi Talib Hospitals in Years 95-96
Microbiology and Infectious DiseasesFrom the point of view of frequency and importance, Brain vascularaccidents take the first place among all the neural di...Read more
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The role of natural antioxidants in treatment of cancer
Cancer; Prevention, Diagnosis and TreatmentCancer is one of the most common causes of death in advanced industrial societies. With the prevalence and spread of can...Read more
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Pattern of efflux pump genes in imipenem resistant Acinetobacter isolates
Microbiology and Infectious DiseasesAcinetobacter species are opportunistic pathogens and responsible for various types of nosocomial infections. They are i...Read more
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Biological and Molecular Diversity in Telomerase: Characteristics of hTERT in Human, Vertebrates and Yeast
Medical GeneticshTERT (human telomerase reverse transcriptase) is the catalytic subunit of telomerase enzyme, and is essential for its ...Read more
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A simple way for extracting singular porphyrin peaks from total fluorescence spectrum of plasma
Metabolism and Metabolic DiseasesPorphyrins are organic compounds formed from the breakdown of hemoglobin. Any disturbance in porphyrins’ level can be ...Read more
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Biosynthesis of Gold nanoparticles by Areca palm fruit extract
Nano-Biotech MedicalTargeted drug delivery by Gold nano particles (AuNPs) is a new era in pharmaceutical research; i.e. curing tumoral cance...Read more
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Shedding light on new form of combination therapy in acute promyelocyte leukemia
Cancer; Prevention, Diagnosis and TreatmentAlthough physicians have taken a variety approaches for the treatment of acute promyelocytic leukemia (APL), there is no...Read more
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Effect of Zinc Oxide Nanoparticles on expression of proapoptotic BAX and Bcl-2 in Testicular Tissue of NMRI Adult Mice
Nano-Biotech MedicalZinc oxide nanoparticles have numerous applications in medicine and industry. These materials are delivered to the tissu...Read more
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Microfluidic 3D cell-Culture platforms for drug response monitoring: potential applications for individualized cancer treatment
Cancer; Prevention, Diagnosis and TreatmentIndividualized monitoring of drug response is supposed as a main constituent of personalized treatment. Current methods ...Read more
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Antimicrobial susceptibility of Acinetobacter baumannii isolated from different clinical samples in hospitalized patients
Microbiology and Infectious DiseasesAcinetobacter baumannii is a gram negative bacteria, which is cause multidrug-resistant nosocomial infection. Control an...Read more
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Human reovirus destroys liver cancer cell line (Huh-7)
Cancer; Prevention, Diagnosis and TreatmentThe Huh-7 cell line was derived from a liver tumor in a 57-year-old Japanese male patient in 1982. Hepatocellular carcin...Read more
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the role of genetics in diabetes and its complications
Medical GeneticsThe purposes of writing this article are the significant role of genetics in the onset of diabetes, hoping to be treated...Read more
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Design, production and purification of polyclonal antibodies against recombinant human erythropoietin antigens for immunological investigation of pharmaceutical and clinical samples
Nano-Biotech MedicalIn this research, the primary antibody against erythropoietin is produced by injecting pure recombinant human erythropoi...Read more
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Doxycycline loaded Kefiran nanofibers: cell viability improvement
Nano-Biotech MedicalDoxycycline (DOXY) is a second generation tetracycline antibiotic with extensive usage. High concentration of DOXY might...Read more
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Effect of Valproic Acid on Proliferation and Apoptosis of Colon Cancer HT 29 Cell Line
Cancer; Prevention, Diagnosis and TreatmentThe structure of chromatin is made up of DNA, histones, and non-histone proteins with the basic repeating unit, nucleoso...Read more
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The effects of vitamin D3 supplement on clinical course of patients with migraine
Nutrition and HealthMigraine is one of the most common headaches all around the world including Iran. Considering that some studies have sho...Read more
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Association between mtDNA D-Loop Mutation and secondary lung cancer
Cancer; Prevention, Diagnosis and TreatmentLung cancer is one of the leading cause of cancer death in the world. The aim of this study was to determine deletions ...Read more
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Atopic Dermatitis and treatment
Nutrition and Health• diagnostic criteria Atopic dermatitis is difficult to define because of its variable morphology and distribution an...Read more
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Evaluation of Catalase (CAT) expression in Acute Myeloid leukemia Patients
Cancer; Prevention, Diagnosis and TreatmentAcute myeloid leukemia is a heterogeneous neoplastic malignancy, that despite considerable progress in many of its molec...Read more
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Function of Diabetes Mellitus on the Body, Diagnosis until Treatment
Medical GeneticsDiabetes mellitus is a metabolic pathway in which the insulin hormone is secreted or incompletely secreted; it is a meta...Read more
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Role of Potential tumor marker in several cancer: Diagnostic and Treatment
Cancer; Prevention, Diagnosis and TreatmentTumor markers are substances produced by the tumors or by other cells of the body in response to cancer. They are produc...Read more
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TP53 hotspot mutations and expression of c-Myc oncogenes in astrocytoma and meningioma
Medical GeneticsMost studies have shown that there are association between the development and malignancy of brain tumors and tumor supp...Read more
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Cloning of Human THAP11 Gene in Lentiviral Vector
Stem cell and Medical ApplicationsThap11, the most recent described member of THAP domain family, which is in volved in cell proliferation and described a...Read more
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Green synthesis of Gold nanoparticles by water extract of common nettle leaves
Nano-Biotech MedicalGold nano particles (AuNPs) are being considered for cancer treatments for targeted drug delivery in pharmacology and me...Read more
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Mesenchymal stem cells enhance the metastasis of cervical cancer cell line, CaSki, in 3D cell culture system
Cancer; Prevention, Diagnosis and TreatmentMesenchymal stem cells, also known as mesenchymal stromal cells (MSCs), are attractive for repair and regeneration of ti...Read more
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Effect of letrozole as alternative aromatase inhibitor on development of ovarian follicles and uterine changes in adult NMRI mice strain and their infants
Microbiology and Infectious DiseasesLetrozole is used as an aromatase inhibitor, to increase ovulation induction. This drug is usually prescribed for patien...Read more
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The salivary beta-2microglobulin (β2M) and prostate-specific antigen (PSA) can be used as an alternative to the serum β2M and PSA for diagnosis and monitoring of prostate diseases
Cancer; Prevention, Diagnosis and TreatmentIn recent years, the use of saliva as a specimen, due to its non-invasive and easy access increased. But their roles hav...Read more
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Polymorphisms evaluation of the thiopurine S-methyltransferase gene among the Iranian acute lymphoblastic leukemia population
Medical GeneticsThiopurine S-methyltransferase (TPMT) is a cytosolic enzyme which catalyzing the S-methylation of 6-mercaptopurine and...Read more
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Molecular detection of factor 5 Leiden (G1691A) and its relation with TNF- α gene polymorphism in human abortion
Medical GeneticsAbortion is the most common of pregnancy complications. In the pathogenesis of abortion as a multifactorial disease, gen...Read more
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The association between pre-gravid BMI with fasting glucose and lipid profile in gestational diabetes following Assisted Reproduction.
Women and Reproductive HealthGestational diabetes mellitus (GDM) is one of the most endocrine pregnancy outcomes. High prevalence of GDM was reported...Read more
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Cancer Stem Cell Therapy Based on Nanostructure Drug Vehicle, PMBN-IL3-GA
Nano-Biotech MedicalTo overcome difficulty of cancer treatment by conventional chemotherapy methods, the targeting drug delivery based on Na...Read more
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Determination of physico-chemical properties of Faecalibacterium prausnitzii EVs
Microbiology and Infectious DiseasesFaecalibacterium prausnitzii is one of the most common human gastrointestinal bacteria that has been shown to have sever...Read more
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Optimization of epi-drug combination against Glioblastoma multiform cell line (U251) using Response Surface Methodology
Cancer; Prevention, Diagnosis and TreatmentGlioblastoma multiform (GBM) is the most common and aggressive form of primary brain cancer and has a dismal prognosis, ...Read more
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Synthesis and characterization of Gold Nanoparticles by Isolated Bacterial from Kerman Sarcheshmeh Copper Mine Soil and the study of their cytotoxic properties
Nano-Biotech MedicalThe present study was designed to isolate bacterial strain capable of gold nanoparticles (Au NPs) production followed by...Read more
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A Comparison of the efficacy of Fluconazole-loaded PLGA Nanospheres and Fluconazole on attachment of Candida albicans to hela cell
Microbiology and Infectious DiseasesThe human pathogenic fungus Candida albicans is commonly found on mucosal surfaces, such as the vagina. It has been wide...Read more
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Diagnosis of Cytomegalovirus in Sinusitis by Molecular method
Microbiology and Infectious DiseasesCytomegalovirus is one of the important viruses that can cause a wide range of diseases in humans. Sinusitis is a common...Read more
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The nutritional benefits of Pistacia atlantica
Nutrition and HealthPistacia Atlantica Mutica is a genus of the family Anacardiaceae which consist of different parts such as fruit, leave a...Read more
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The effects of sodium butyrate on the expression of HDAC8 gene in HT-29 colorectal cancer cell line
Cancer; Prevention, Diagnosis and TreatmentSodium butyrate (NaB) is a potent growth inhibitor and initiates cell differentiation for many cell types in vitro. In t...Read more
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Evaluation of Adiponectin Hormone in Diabetic and Non-diabetic Patients
Metabolism and Metabolic DiseasesAdipose tissue is currently considered as a hormonally active system in the control of metabolism and not only as a stor...Read more
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Evaluation of Acholeplasma laidlawii in biologic products by PCR method
Microbiology and Infectious DiseasesContamination of biological products and cell cultures is one of the important problems in producing a good and safe pro...Read more
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THE TOLE OF PROBIOTICS IN PUBLIC HEALTH
Nutrition and HealthIn the last decade, we have seen dramatic changes in understanding the role of foods in improving human health. scientif...Read more
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Crocin suppresses multidrug resistance in MRP overexpressing ovarian cancer cell line
Cancer; Prevention, Diagnosis and TreatmentCrocin, one of the main constituents of saffron extract, has numerous biological effects such as anti-cancer effects. M...Read more
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Simple solution to prevent prostate cancer
Cancer; Prevention, Diagnosis and TreatmentMen above fifty five years old are at high risk for malignant prostate cancer. Currently surgery is the only treatment a...Read more
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Application of cold atmospheric plasma in human and veterinary medicine
Microbiology and Infectious DiseasesIn the last few years plasma medicine has completed the transition from a field of research to actual evidence-based cli...Read more
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A technical overview on the neuronal dysfunction induced by heat stroke on the C57 mice models
Medical GeneticsHeat is an environmental hazard that via increasing core body temperature leads to innate stress with pathological and p...Read more
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The effects of specific expression of Apoptin under control of PSES and PSA promoter on apoptosis of LNCaP cells
Cancer; Prevention, Diagnosis and TreatmentApoptotic effects of viral protein Apoptin has been demonstrated in numerous studies. However, its tumor specificity has...Read more
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Development and implementation of a novel panel consisting 16 STR markers linked to the HLA-gene-cluster applicable for HLA-typing, PND&PGD
Medical GeneticsPGD (Pre-implantation Genetic Diagnosis) in combination with human leukocyte antigen (HLA) matching, allow not only sele...Read more
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Discrimination of Leishmania species by Arginine permease gene AAP3as a suitable molecular tool for detection and genetic proximity analysis
Microbiology and Infectious DiseasesLeishmaniasis presents itself in different clinical manifestations such as: visceral Leishmaniasis, Cutaneous Leishmania...Read more
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The influence of lactobacillus fermentum cytoplasmic extract, isolated from traditional cheese (kuzeh) on the expression of p53 gen in K562 cancerous array via a quantitative Real time PCR method
Cancer; Prevention, Diagnosis and Treatmentthe probiotics are able to induce apoptosis in cancerous cells. chronic myelocytic leukemia (cancerous array of K562) is...Read more
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Effect of Praziquantel Drug on Prevention of Afflicting Dogs with Cestode Echinococcus Granulosus
Microbiology and Infectious DiseasesAwareness of the impact range of praziquantel drug on prevention of afflicting dogs with echinococcus granulosus parasit...Read more
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Canavan disease: clinical and molecular review
Medical GeneticsCanavan disease is a rare autosomal recessive disorder that predominantly affects the central nervous system with white ...Read more
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Evaluation of Interleukin 10 Gene Promoter Polymorphisms of -592A/C and -1082A/G Region Among Obese Individuals with Type 2 Diabetes in Alborz Province
Metabolism and Metabolic DiseasesToday diabetes is one of the most prevalent noncontagious diseases around the world. There is strong evidence showing in...Read more
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Investigating the specificity of the specific lytic bacteriophage against Salmonella bacteria and its effect on the hep2 cell line
Microbiology and Infectious DiseasesResistance to antibiotic treatments is one of the increasing problems. Therefore, alternative methods to reduce antibiot...Read more
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Hepatoprotective effects of magnesium sulfate on pentylenetetrazol-induced seizures in male Wistar rats
Nutrition and HealthMagnesium is the second most abundant cation (after potassium) in the cell and plays an important role in various biolog...Read more
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Evaluation of the level of some of the Trace elements in the sprayer workers
Metabolism and Metabolic DiseasesPesticides and toxins have deleterious effects on human health and can affect the biochemical factors of the body. There...Read more
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Interference of Dopamine D2 Receptors and Food Restriction on Changing Anxiety Behavior and Serum Biochemical Factors in Adult Male Rats
Nutrition and HealthBackground: Food restriction (FR) and dopaminergic system affect on anxiety behavior, but it has not been determined the...Read more
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Triplet repeats in Androgen receptor and it's relation with cardiovascular disease
Medical GeneticsCardiovascular disease is one of the main cause of death in all around the world and researches indicated that in United...Read more
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Perineal massage during pregnancy and perineal safety during childbirth
Women and Reproductive HealthIntroduction: Women frequently suffer from perineal trauma during childbirth, especially during the first childbirth. ...Read more
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Green synthesis of Silver nanoparticles by Alhagi camelorum gum
Nano-Biotech MedicalSilver nano particles (AgNPs) are used in textiles, cosmetics, tooth brushes, home appliances, food packages and many ot...Read more
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The cultural, ethical and religious challenges of society related to assisted reproductive techniques
Women and Reproductive HealthInfertility is a worldwide problem of high prevalence of reproductive health. Significant advances in assisted reproduc...Read more
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An Evaluation of Tissue Destruction Time in Phrenic Nerve after Death and Counting the Number of Nerve Fibers in C3, C4 and C5 Branches
Cancer; Prevention, Diagnosis and Treatmentمقدمه اعصاب فرنیک چپ و راست، محرک اصلی عضلة دیافراگم میباشند( .)5ای...Read more