Toxoplasmosis is a shared human-animal disease with worldwide distribution caused by toxoplasma gondii. more than half of the world's population is seropositive for toxoplasmosi. the aim of this study was to evaluate the changes in igm and igg anti-toxoplasma immunoglobulins in women referred to yasuj medical centers
Methods
A total of 172 blood samples were collected from pregnant women referred to yasuj medical centers during the first 6 months. the sera were tested for igg and igm titration with vidas kits.in addition, demographic characteristics of the women were obtained through appropriate questionnaires. finally, the molecular detection of the b1 gene was performed
Results
Positive igg and igm titers were identified in the sera of 15.69% and 2.32% of the pregnant women, respectively. subsequently, three patients were identified for the presence of b1 gene by pcr assay. the higher frequency of positive titers was associated with older age. there was no statistically significant relationship between having the cat and the presence of b1 gene(p-value>0/999). the prevalence of abortion in positive toxoplasmosis patients was significantly more than other patients (p-value>0/0001)
Conclusion
The results of this study, based on the climatic conditions of yasuj, have been reported lower than the similar studies in tropical regions. it is recommended that women be tested for toxoplasmosis, especially during the first three months of pregnancy
