Mahdieh Salimi*
National Institude of Genetic Engineering and BiotechnologyTehran, Tehran
Abstracts, [Author]
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Evaluation of antioxidant activity and cytotoxicity of an ethanol extract of leaves and fruits of Mespilus germanica on human lung cancer A549 cell line
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the most common cancers and natural products extracted from medicinal plants can play an important role i...Read more
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Synergistic Antibacterial Activity of Zinc Oxide Nanoparticles with Cuminum cyminum L. Essential Oil against the Food-Borne Pathogens Salmonella enterica
Nano-Biotech MedicalOne of the ways to control of pathogenic microorganisms in foods is to use preservatives and antimicrobial agents. Diffe...Read more
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Determination of physico-chemical properties of Faecalibacterium prausnitzii EVs
Microbiology and Infectious DiseasesFaecalibacterium prausnitzii is one of the most common human gastrointestinal bacteria that has been shown to have sever...Read more
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Isolation and of merkel cell polyomavirus(MCV) in patient with skin cancer
Cancer; Prevention, Diagnosis and TreatmentSkin cancer is the most common malignancy in the world, with high disability and mortality is relatively low (Except for...Read more
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A study on the interaction of angiotensin I converting enzyme inhibitory peptide with human hemoglobin protein by conductometry method in the absence and presence of a low frequency electromagnetic fi
Metabolism and Metabolic DiseasesHigh blood pressure, or hypertension, is a chronic disease in which the blood pressure goes up. Angiotensin converting e...Read more
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Function of Diabetes Mellitus on the Body, Diagnosis until Treatment
Medical GeneticsDiabetes mellitus is a metabolic pathway in which the insulin hormone is secreted or incompletely secreted; it is a meta...Read more
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Study the expression rate of claudin-1 gene in Crocus sativus (saffron ) treated AGS cell lines
Cancer; Prevention, Diagnosis and TreatmentClaudins are the main structural and functional proteins of tight junctions in epithelial cells. The altered expression...Read more
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Evaluation of Acholeplasma laidlawii in biologic products by PCR method
Microbiology and Infectious DiseasesContamination of biological products and cell cultures is one of the important problems in producing a good and safe pro...Read more
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The effect of Rosa canina extract on Bax gene expression in gastric adenocarcinoma cell line(AGS)
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is the most common cancer in the world. It occurs as a result of many factor and there is massive invest...Read more
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Synergistic effect of berberine and theophylline on apoptosis induction in MDA-MB-231 cells
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the most common type of cancer and a leading cause of cancer mortality among women. Berberine is an iso...Read more
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Association between Heat shock protein 70 gene polymorphism and risk of multiple sclerosis in Iranian population
Medical GeneticsMultiple sclerosis (MS) is a chronic disease of the central nervous system and one of the most common causes of neurolog...Read more
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The antiproliferative and cell cycle arrest effects of Botox on MCF-7and PC-3 cell line
Cancer; Prevention, Diagnosis and TreatmentBotulinum toxin (Botox) is the most potent biological toxin known to against human life. It can be used as a selective a...Read more
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Simple solution to prevent prostate cancer
Cancer; Prevention, Diagnosis and TreatmentMen above fifty five years old are at high risk for malignant prostate cancer. Currently surgery is the only treatment a...Read more
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Expression of CD74 in Ovarian cancer
Medical GeneticsOvarian cancer is a cancer that forms in or on an ovary. The pro-inflammatory cytokine migration inhibitory factor (MIF)...Read more
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A foundation for universal T-cell based adoptive immunotherapy
Cancer; Prevention, Diagnosis and TreatmentThe patient-specific autologous therapy could be a significant limiting factor in the large-scale exploitation of CAR te...Read more
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Investigation efflux pump -activated fluoroquinolone resistance in pseudomonas aeroginosa multi drug resistance isolates by CCCP inhibitor
Microbiology and Infectious DiseasesPseudomonas aeruginosa is the third cause of nosocomial infections after Staphylococcus aureus and E. coli .One of the p...Read more
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Anemia, a common disease in hemodialysis patients
Metabolism and Metabolic DiseasesChronic renal failure stage of renal insufficiency it is said that all the no longer able to repel and not toxic waste a...Read more
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isolates from Kermanshah province submitted at National Animal tuberculosis reference Laboratory at Razi institute
Microbiology and Infectious DiseasesTuberculosis is a zoonotic which has long been recognized and is still one of the most life-threatening diseases. Tuberc...Read more
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Controversy in reports about TNF-α (rs361525) related to susceptibility to Hepatocellular Carcinoma (HCC): a meta-analysis
Cancer; Prevention, Diagnosis and TreatmentTumor necrosis factor-α play a very important role in the development and progression of hepatocellular carcinoma. Pre...Read more
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FGF10: Type III Epithelial Mesenchymal Transition and Invasion in Breast Cancer Cell Lines
Cancer; Prevention, Diagnosis and TreatmentMetastasis is one of the important characteristics of a cancer cell. the process called epithelial mesenchymal transitio...Read more
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Biosynthesis of Silver nanoparticles using water extract of Ziziphus spina_cheristi Leaves
Nano-Biotech MedicalSilver nanoparticles (AgNPs) have been widely used as an antiseptic against a wide range of microorganisms. The goal of ...Read more
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Investigation Of Antimicrobial Effect Of Magnetical Silver And Silver-Titanium Dioxide Nanocomposites On Commonly Bacteria Of Urinary Infects
Nano-Biotech MedicalRecently, developed nano composite with highly efficient antimicrobial properties are considered. In this study, A new m...Read more
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Investigating the toxicity of PEGylated Gold Nanoparticles and red LED light on Ecoli bacteria
Nano-Biotech MedicalToday, the emergence and spread of antibiotic-resistant strains of bacteria have become a major challenge to public heal...Read more
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Effects of 5-aza-2ˈ-deoxycytidine and Valproic Acid on Epigenetic-modifying DNMT1 Gene Expression, Cell Growth Inhibition and Apoptosis Induction in Hepatocellular Carcinoma WCH-17 cell line
Cancer; Prevention, Diagnosis and TreatmentIntroduction DNA molecule of the eukaryotic cells is found in the form of a nucleoprotein complex named chromatin....Read more
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Removal of Nickel (II) From Drinking Water Using Thiol-Functionalized Chitosan
Nano-Biotech MedicalSome heavy metals are the causes of various diseases among humans. Thus, removing heavy metals is necessary in order to ...Read more
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Non-syndromic obesity in infertile men and structural chromosomal abnormalities
Medical GeneticsObesity is commonly classified into subgroups depending on suspected etiology: monogenic obesity (extremely severe obesi...Read more
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Investigation of microRNAs involved in the EGFR molecular pathway as a biomarker in early detection of colorectal cancer
Medical GeneticsColorectal cancer (CRC) is one of the most common cancers in the world. The highest incidence of CRC in Europe, North Am...Read more
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TYCSB culture media reliability for S. mutans isolation
Microbiology and Infectious DiseasesAlthough the clinical significance of dental caries is well recognized, the exact etiology of the condition is not under...Read more
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An investigation on the structure and function of the cell surface breast-specific antigens for development a new generation of immunotoxins
Cancer; Prevention, Diagnosis and TreatmentBreast cancer with heterogeneous features in morphology, clinic, and responses to therapeutic options, is one of the mos...Read more
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Evaluation of cytotoxicity of rainbow trout extracts (Oncorhynchus mykiss) on gastric cancer cell line (AGS)
Cancer; Prevention, Diagnosis and Treatmentrainbow trout due to high levels of essential fatty acids, omega-3 has been identified as one of the important factors i...Read more
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Aloe Vera Herbal Effects on Diabetes Treatment and Prevention: A Systematic Review
Metabolism and Metabolic DiseasesDiabetes is one of the most common metabolic diseases that affects more than 150 million people in the world. It is the ...Read more
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Mediterranean dietary pattern adherence modify the association between FTO genetic variations and obesity phenotypes
Nutrition and HealthThere is an increasing interest in examining whether dietary patterns modify the association of fat mass and obesity ass...Read more
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An innovative field of plasma application for medical therapy
Microbiology and Infectious DiseasesPlasma medicine is an innovative and emerging field combining plasma physics, life science and clinical medicine. Recent...Read more
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Investigating the Epidemiology of Concussed Patients, Hospitalized in Khatam al-Anbyia and Ali ibn Abi Talib Hospitals in Years 95-96
Microbiology and Infectious DiseasesFrom the point of view of frequency and importance, Brain vascularaccidents take the first place among all the neural di...Read more
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Prognostic value of MSI status in colorectal cancer patients
Cancer; Prevention, Diagnosis and TreatmentMicrosatellite instability (MSI) causes hereditary non-polyposis colorectal cancer (HNPCC), and occurs in about 15 per c...Read more
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Effects of serotonin on adiponectin secretion and leptin gene expresions in rats
Women and Reproductive HealthSerotonin is a neurotransmitter which stimulates the secretion of sexual hormones . The nuclei of Hypothalamus involved...Read more
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The effect of manual acupuncture on anthropometric parameters in obese and overweight patients
Nutrition and HealthObesity is a chronic disease which is on the increase. Treatments of obesity include diet therapy, exercise, behavior th...Read more
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Diagnosis of Cytomegalovirus in Sinusitis by Molecular method
Microbiology and Infectious DiseasesCytomegalovirus is one of the important viruses that can cause a wide range of diseases in humans. Sinusitis is a common...Read more
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Effect of Valproic Acid on Proliferation and Apoptosis of Colon Cancer HT 29 Cell Line
Cancer; Prevention, Diagnosis and TreatmentThe structure of chromatin is made up of DNA, histones, and non-histone proteins with the basic repeating unit, nucleoso...Read more
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3D Graphene Framework: A High-Performance Adsorbent for Antibiotics
Nutrition and HealthAntibiotics have been considered as emerging pollutants due to their continuous input and persistence in the aquatic eco...Read more
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Food Patterns and Framingham Risk Score in Iranian Adults: Tehran Lipid and Glucose Study: 2005-2011
Nutrition and HealthHealthy dietary habits can prevent cardiovascular diseases (CVD). The aim of the present study was to investigate the as...Read more
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Studying the relation of blood lead level with the thyroid hormones and blood factors
Metabolism and Metabolic DiseasesLead has many applications in the industry but does not play a specific physiological role in the body. According to per...Read more
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Osteo therapy and the role of chitosan-alginate in osteoarthritis
Nano-Biotech MedicalOsteoarthritis (OA) is a progressive skeleton disturbance that it is usually related with considerable inability and lim...Read more
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Investigating the relationship between metacognitive beliefs, and premenstrual syndrome and depression caused by that, in female students studying at Tehran University of Medical Sciences
Women and Reproductive HealthThe purpose of this research was studying the relation between meta-cognitive beliefs on premenstrual syndrome and depre...Read more
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The Role of Nanobiotechnology in Identification and Treatment Lung Cancer
Nano-Biotech MedicalNanotechnology is the engineering of functional systems at the molecular scale. Therefore, it is possible to combine nan...Read more
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A novel technique to estimate sex ratio in semen
Women and Reproductive HealthOffspring sex is one of the most important factors in controls sex-linked genetically transferred diseases and also for ...Read more
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Study of gene expression and promoter methylation pattern of AKAP4 as possible breast cancer diagnostic marker candidate
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is an important health issue for millions of women around the world. Recently, a new group of tumor-associ...Read more
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Association of umbilical coiling index with hypothyroidism and gestational diabetes mellitus.
Metabolism and Metabolic DiseasesGestational diabetes mellitus [GDM] and hypothyroidism are prevalent and potentially serious condition which may put mot...Read more
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Genetic Diversity and Phylogenetic Analysis of the Iranian Leishmania Parasites Based on HSP70 Gene PCR-RFLP and Sequence Analysis
Microbiology and Infectious DiseasesDespite the broad distribution of leishmaniasis among Iranians and animals across the country, little is known about the...Read more
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Investigation of Lead and Chromium Elements in Female Patients with Breast Cancer Before and After Chemotherapy
Cancer; Prevention, Diagnosis and TreatmentHeavy metals such as lead and chromium can be in various forms, including free ions, metal compounds or carcinogenic par...Read more
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Sugar-sweetened beverages increase cardiovascular risk in diabetic patients
Nutrition and HealthSugar sweetened beverages (SSBs) are any type of sugar-added drinks like soft drink, syrup, etc. SSBs consumption has in...Read more
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Curcumin regulates proinflammatory signaling function of thrombin in endothelial cells
Microbiology and Infectious DiseasesCurcumin regulates proinflammatory signaling function of thrombin in endothelial cells...Read more
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A brief review of regenerative dentistry
Stem cell and Medical ApplicationsTissue regeneration idea has been formed by stem cells identifying and tissue engineering techniques. Stem cells can be ...Read more
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Microfluidic 3D cell-Culture platforms for drug response monitoring: potential applications for individualized cancer treatment
Cancer; Prevention, Diagnosis and TreatmentIndividualized monitoring of drug response is supposed as a main constituent of personalized treatment. Current methods ...Read more
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Evaluation of PRC1 gene expression in gastric cancer patients
Cancer; Prevention, Diagnosis and Treatment: Cancer is one of the most important causes of death. Among cancers, gastric cancer is the fourth most common cancer an...Read more
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Antibacterial effects of curcumin encapsulated in micelle nanoparticles on mexX gene expression in ciprofloxacin resistant isolates of Pseudomonas aeruginosa in Guilan
Nano-Biotech MedicalCurcumin, a polyphenolic compound fromturmeric (Curcuma longa) is a pharmacologically safe agent that has antibacterial ...Read more
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In silico analysis of Siglec14 as a target for hsa-let-7e-5p
Medical GeneticsSialic acid-binding immunoglobulin-type lectins (Siglecs) are transmembrane proteins that are expressed on the cell surf...Read more
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Investigation of toxicity effect of 4-Mepgc and 4-No2pgc on the K562 cell line (chronic myeloid leukaemia)
Cancer; Prevention, Diagnosis and TreatmentLeukemia is a particular type of cancer characterized by the failure of cell death or disability in the differentiation ...Read more
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personalized medicine in oncology
Medical GeneticsThe term peronalized medicine is used for the identification of optimal drug type and optimal drug dosage for individual...Read more
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Comparative investingation of effects of the agricultural pesticides (diazinon and chlorpyrifos) on spermatogenesis in male BALB/c male mice
Nutrition and HealthDiazinon and chlorpyrifos are kind of organophosphate toxins used for agricultural pests. These toxins control acetylch...Read more
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Application of cold atmospheric plasma in human and veterinary medicine
Microbiology and Infectious DiseasesIn the last few years plasma medicine has completed the transition from a field of research to actual evidence-based cli...Read more
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Examination of mutations in QRDRs in ParC, ParE genes Salmonella Clinical Examples of Zahedan Hospitals
Microbiology and Infectious DiseasesSalmonellosis is a major public health problem worldwide. Although most Salmonella infections result in mild self-limiti...Read more
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the review of The implications in toxicity Metabolomics of Delta9-tetrahydrocannabinol
Metabolism and Metabolic DiseasesThe plant Cannabis sativa has been used for the effects of its psychoactive resins that name is (cannabinoid δ-9-tetrah...Read more
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Evaluating the genetic variations of ARPT1 gene in infertile men with abnormality in sperm head morphology referring to Royan institute.
Medical GeneticsThe evaluation of human sperm morphology is a controversial aspect of the semen analysis for the determination of male...Read more
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Determination of antibiotic-resistant strains of isolated Brucella in Markazi Province
Microbiology and Infectious DiseasesBrucellosis is one of the common diseases of man and animals are caused by bacteria of the genus Brucella. The purpose o...Read more
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Study of MiRNA-873 expression in Ectopic pregnancy, Endometriosis and Ovarian cancer (review)
Medical GeneticsMicroRNAs are small non-coding RNA molecules that have functions in post-transcriptional regulation of gene expression. ...Read more
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Berberine induced cell death of human colon cancer HT-29 through mediating of PARP
Cancer; Prevention, Diagnosis and TreatmentBerberine is an isoquinoline which has many various pharmacological activities, including anticancer activities. Poly (A...Read more
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Evaluation of the effect of saturated and unsaturated fatty acids on the growth and production of outer membrane vesicles in human gut microbiota
Microbiology and Infectious DiseasesA diverse and complex symbiotic microbial community colonize in human host,espicially in the gastrointestinal tract,refe...Read more
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Medicinal plants in the treatment of infertility
Women and Reproductive HealthInfertility is disability of a couple to reach pregnancy for more than one year despite regular sexual intercourse. The ...Read more
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Skin anti-ageing potential of Lactobacilli exopolysaccharides (EPSs) on human fibroblast
BeautySkin aging is a complex biological process influenced by a combination of endogenous or intrinsic and exogenous or extri...Read more
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β-Cyclodextrin Modified Graphene Oxide Bionanocomposite for pH-sensitive Release of Anti-cancer Drug
Nano-Biotech MedicalGraphene is a multifunctional carbon nanomaterial and could be utilized to develop platform technologies for cancer ther...Read more
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Effect of Zinc nanoparticle on p53 expression in K562 cell line by Real Time PCR
Medical GeneticsChronic myeloid leukemia is a cancer of blood which is identified by bcr/abl translocation. Imatinib is a tyrosine kinas...Read more
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Anti-inflammatory activity of Caspian Cobra (Naja naja oxiana) snake Venom in EAE model of MS
Medical GeneticsMultiple sclerosis (MS) is a chronic neuroinflammatory demyelinating disorder of the Central Nervous System (CNS) with a...Read more
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The association of the H19 rs217727 polymorphism and Preeclampsia
Medical GeneticsPre-eclampsia is a pregnancy specific disorder; which is defined as pregnancy-induced hypertension and proteinuria. H19 ...Read more
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Benefical Effects of hydroalcoholic extract of fenugreek seeds on some Biochemical factors and oxidative stress in high-fructose diet-induced metabolic syndrome in rats
Metabolism and Metabolic DiseasesBackground: Fenugreek (Trigonella foenum graecum) is a traditional herbal plant. seeds of Fenugreek have several propert...Read more
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Managing The Abnormal Papsmear In Pregnancy
Cancer; Prevention, Diagnosis and TreatmentCervical cancer is the most common malignancy diagnosed during pregnancy . The incidence of abnormal pap smear in pregna...Read more
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Survey of Changes gene expression levels of SAP 1-3 Candida albicans samples treated with treated with Fluconazole-loaded PLGA Nanospheres, in comparsion with drug Fluconazole
Microbiology and Infectious DiseasesSecreted Aspartyl Proteinase (SAP) is one of the main virulent factors in the pathogenesis of Candida. This enzyme is en...Read more
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Evaluation of antioxidant activity and cytotoxicity of an ethanol extract of leaves, fruits and calyx of Physalis alkekengi on human lung cancer A549 cell line
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the most common cancers and chemotherapy cancer treatment is one of the methods, but because of the lack ...Read more
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Investigating the Relationship between Polymorphism of p22phox in Smoker Population with Chronic Obstructive Pulmonary Disease (COPD) and Susceptibility to Disease
Medical GeneticsCOPD (chronic obstructive pulmonary disease) is a slowly progressive condition characterized by airflow limitation, whic...Read more
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MYH9 gene and urinary albumin excretion in Iranian diabetic patients
Medical GeneticsDiabetic nephropathy (DN) is one of the most common causes of end stage renal disease (ESRD).: Myosin heavy chain 9 (MYH...Read more
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Whole-Exome Sequencing Identifies R1279X of MYH6 to be Associated with Congenital Heart Disease and Other Malformations
Medical GeneticsMyosin VI, encoded by MYH6, is expressed dominantly in human cardiac atria and plays consequential roles in cardiac musc...Read more
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LPS Effects on induction of regulatory T cells in peripheral blood mononuclear cells in endometriosis patients
Women and Reproductive HealthEndometriosis is an estrogen-dependent chronic inflammatory disease affecting women in reproductive ages. Regulatory T c...Read more
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Atopic Dermatitis and treatment
Nutrition and Health• diagnostic criteria Atopic dermatitis is difficult to define because of its variable morphology and distribution an...Read more
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Evaluation of magnesium & copper levels and antioxidant power in serum of women with endometriosis before and after administration of N-acetylcysteine
Women and Reproductive HealthEndometriosis is caused by the presence of ectopic endometrial stromal outside the endometrial cavity. The oxidative str...Read more
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The Bioinformatic prediction of selected miRNAs role in regulation of cell death pathways in Parkinson’s disease
Medical GeneticsParkinson's disease (PD) is the second most common neurodegenerative disease. Due to its unknown etiology and pathology,...Read more
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Evaluation of cytotoxicity, viability and induced oxidative stress by Nickel (II) complex of thiosemicarbazone
Cancer; Prevention, Diagnosis and TreatmentThiosemicarbazones and their metal complexes have significant biological activities including anticancer, antibacterial,...Read more
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Evaluation of cardiac differentiation potential of menstrual blood- derived stem cells seeded in biocompatible Bombyx mori silk fibroin scaffold in co-culturing with neonatal rat Cardiomyocytes
Stem cell and Medical ApplicationsCardiovascular disorders are leading cause of million deaths each year which reveals the significance of current limitat...Read more
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Investigation of antioxidant capacity of silver nanoparticles with Laurencia caspica seaweed on liver cancer cell line (HepG2)
Nano-Biotech MedicalHepatocellular carcinoma is a type of hepatocellular carcinoma that occurs most often in cases of hepatitis B and C, or ...Read more
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The effects of methanolic soy extract on ovary tissue modification in model of polycystic ovary syndrome as an inflammation state
Women and Reproductive HealthIntroduction and Objective: Chronic low-grade subclinical inflammation has been increasingly recognized as an interposer...Read more
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case report of Albinism with pseudo dominant inheritance
Medical GeneticsOculocutaneous albinism type 1 is characterized by hypopigmentation of the skin and hair and the distinctive ocular chan...Read more
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Evaluation of the level of some of the Trace elements in the sprayer workers
Metabolism and Metabolic DiseasesPesticides and toxins have deleterious effects on human health and can affect the biochemical factors of the body. There...Read more
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TThe Biological Effects of Aqueous Extract of Ephedra major on the Development of Balb/C Mouse Embryos 7Th to 10Th Days of Pregnancy
Nutrition and HealthAqueous extract of Ephedra major used as a drug for blood pleasure, sleep disorder and lose weight. But it is effects on...Read more
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The effect of Bioactive glass on Adipose-derived MSC osteogenesis in 3D cultures
Stem cell and Medical ApplicationsRegenerative medicine is an emerging field of biotechnology that combines various aspects of medicine, cell and molecula...Read more
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Effects of Rosmarinic acid on oxidative stress and total antioxidant capacity in vivo study
Metabolism and Metabolic DiseasesDiabetic disease is characterized by chronic hyperglycaemia. Numerous studies have shown that in diabetes mellitus, ther...Read more
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Study of matrix metallo proteinase (MMP)-9 gene & its phylogeny tree as a critical gene in metastases
Medical GeneticsThere has been a clear connection between MMPs,ECM degradation & cancer cell invasion. Matrix metalloproteinase(MMP)-9, ...Read more
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The impact of the vaginal probiotic lactobacillus on the prevention and treatment of cervical cancer
Cancer; Prevention, Diagnosis and TreatmentToday, cervical cancer is the second most common cancer after breast cancer among women and it`s considered dangerous ...Read more
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Design and evaluation of a selective delivery system to induce antimiR-155 function
Nano-Biotech MedicalDeveloping RNA/DNA aptamer-miRNA chimera represents an effective approach in targeted gene therapy of cancer. In additio...Read more
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Effect of Staphylococcus aureus isolates in food samples on hep2 cell line
Microbiology and Infectious DiseasesStaphylococcus aureus produces a range of protein-rich toxins and also extracellular pathogens that contribute to bacter...Read more
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The effect of vinorelbine on HMG proteins in lung cancer A549 cells
Cancer; Prevention, Diagnosis and TreatmentVinorelbine is a semisynthetic vinca alkaloid antitumor drug, widely used in the treatment of cancers such as advanced n...Read more
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Antimicrobial susceptibility of Acinetobacter baumannii isolated from different clinical samples in hospitalized patients
Microbiology and Infectious DiseasesAcinetobacter baumannii is a gram negative bacteria, which is cause multidrug-resistant nosocomial infection. Control an...Read more
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The effects of specific expression of Apoptin under control of PSES and PSA promoter on apoptosis of LNCaP cells
Cancer; Prevention, Diagnosis and TreatmentApoptotic effects of viral protein Apoptin has been demonstrated in numerous studies. However, its tumor specificity has...Read more
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Prevalence of gastric cancer in the patients undergoing bariatric surgery
Cancer; Prevention, Diagnosis and TreatmentIntroduction and goal: The number of obese people has grown up to 1.9 billion worldwide, that a large number of complica...Read more
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Apoptotic Effect of Tamoxifen on Hepatocellular Carcinoma Hep G2 Cell Line
Cancer; Prevention, Diagnosis and TreatmentHepatocellular carcinoma (HCC) is the sixth most common cancer, and the third most common cause of cancer-related death...Read more
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Hydroxyapatite-Gelatin-bone marrow stromal cells construct as an excellent bone graft in animal model
Stem cell and Medical ApplicationsBone healing of critical-sized defects are one of the most challenging orthopaedic problems. In the current study, the e...Read more
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Investigation the effect of low intensity pulsed ultrasound (LIPUS) on proliferation of G 292 osteosarcoma cells on 3D porous PLGA/β-TCP scaffold within perfusion bioreactor
Stem cell and Medical ApplicationsInvestigation the effect of low intensity pulsed ultrasound (LIPUS) on proliferation of G 292 osteosarcoma cells on 3D p...Read more
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Down-Regulation of Bcl-2 and Mcl-1 by MiRNA-15 and 16 Synergistically Enhances the Apoptotic Effects of ABT-199 and Fludarabin in CLL Cells
Cancer; Prevention, Diagnosis and TreatmentMiRNA-15 and 16 can act as a tumor suppressor gene by interfering with Bcl-2 and mcl-1. Studies have demonstrated that o...Read more
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The Anticancer Effect of Plant Aqueous Extracts of Aloe Vera in Gene Expression Bax and Bcl-2 on Gastric Adenocarcinoma AGS Cells
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is a major cause of cancer death. In terms of incidence is the fourth most common cancer and the second l...Read more
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Reproductive Health Training Program on Students in IRAN: An Action Research Approach
Women and Reproductive HealthTransition from adolescence to adulthood is one of the important periods in the individual life. New behaviors are learn...Read more
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Genes involved into both alternative splicing and aging pathways as biomarkers for Parkinson Disease diagnosis
Medical GeneticsParkinson's Disease is a degenerative movement disorder that exhibit symptoms through progressive loss of dopaminergic...Read more
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Tuberculosis is a common HIV infection, control and treatment
Microbiology and Infectious DiseasesPoints out Pulmonary that more than all the be without lymph node, pylorus , Urinary tract , bones and joints , meninge...Read more
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Computer aide discrimination of the ovarian lesions by CT scan images
Cancer; Prevention, Diagnosis and TreatmentTo explore diagnostic potential of computerizing texture analysis (TA) methods in discrimination of the normal, benign...Read more
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Anti-cancer effect of redroot pigweed as weed plant species
Cancer; Prevention, Diagnosis and TreatmentLeukemia cancer is currently one of the major causes of cancer-related deaths among humans. Extracts of plants including...Read more
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The effect of berberin on histone H1 in lung cancer A549
Cancer; Prevention, Diagnosis and TreatmentBerberin, a naturally occurring isoquinoline alkaloid, is present in a number of important medicinal plants. Berberin ha...Read more
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Evaluating the genetic variations in functional domains coding regions of MSMB in infertile men with unexplained infertility
Medical GeneticsΒ-Microseminoprotein(MSMB) is one of the most abundant proteins in human seminal plasma. This protein binds to head and...Read more
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Investigation of epigenetic effects of Disulfiram on the demethylation of RASSF1A gene promoter in breast cancer cell line MCF-7
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the most common type of cancer among women with very high mortality rates in the world. Genetic and epi...Read more
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Efficacy of Bone Marrow Mesenchymal Stem Cells and an Amniotic Membrane on the Number of Mast Cells and Degranulation in Random Skin Flaps in Rats
Stem cell and Medical ApplicationsSkin flap procedures are usually used in plastic surgery. Failing can follow, lead to the necrosis of the flap. Therefor...Read more
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Association of Cytochrome P450 2C19 (CYP2C19) gene polymorphism and the risk of endometriosis in Iranian population
Women and Reproductive HealthEndometriosis is a chronic disease that is characterized by the occurrence of endometrial glands and stroma outside the ...Read more
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Cell-Penetrating Peptides and Tumor Targeting Peptides: achievements and challenges in application for cancer treatment
Cancer; Prevention, Diagnosis and TreatmentDespite significant advancement in the anti-cancer drugs recently, cancer still remains one of the leading causes of dea...Read more
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Development of an Antagonistic TGF-β by Directed Blocking of its TβRI Binding Site to Inhibition TGF-β Signaling
Cancer; Prevention, Diagnosis and TreatmentTransforming growth factors beta (TGF-βs) play vital roles in regulating cell growth, differentiation and inflammation....Read more
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A Comparison of the efficacy of Fluconazole-loaded PLGA Nanospheres and Fluconazole on attachment of Candida albicans to hela cell
Microbiology and Infectious DiseasesThe human pathogenic fungus Candida albicans is commonly found on mucosal surfaces, such as the vagina. It has been wide...Read more
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Operational study of plastination as an alternate method for dissection
Nano-Biotech MedicalSince, two-thirds of the approved Zoology Laboratory syllables, defined by the Ministry of Science, Research and Technol...Read more
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Streptococcus mutans detection in Dental Plaque and saliva Samples
Microbiology and Infectious DiseasesDental caries is one of the most common prevailing disease in humans and a significant public health problem worldwide. ...Read more
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Omega-3 and its effects on colorectal cancer
Cancer; Prevention, Diagnosis and TreatmentCancer as the second leading cause of death has always been a threat to human life and due to its peculiar nature and la...Read more
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The effects of anticancer of 7-hydroxycoumarine on the colon cancer cell line (HT29) and the normal mouse fibroblast cells (L929)
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer it is a lethal and common cancer. due to the development of drug resistance to chemical drugs, the ne...Read more
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Toxic effects of Selenite and need to bio removal of it
Nutrition and HealthSelenium is an important micronutrient for human and animal health, however it is toxic slightly above homeostatic requi...Read more
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Lipase adsorbtion on the single layer geraphene oxide dependes on pH and temperature
Nano-Biotech Medicalgraphene oxide (GO) has been used as a matrix for lipase immobilization. GO chemical properties are reported beneficial ...Read more
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Frequency and Pattern of Resistance of AmpC-Beta-lactamase gene in Clinical isolates of Klebsiella pneumoniae from Zahedan Educational Hospitals
Microbiology and Infectious DiseasesThe detection of CTX-M-15 genes in ESBLs produced by Klebsiella pneumoniae strains provides useful information on epidem...Read more
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Analysis of hypermethylation of NFK-B ،TRAF1 and TRAF2 genes in patients with oral squamous cell carcinoma
Medical GeneticsCancer is a fatal disease caused mainly by environmental factors that mutate genes encoding critical cell-regulatory pr...Read more
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ELISA Cross-Reactivity method to confirm recombinant fliC from salmonella typhimurium and evaluate impurities in purified recombinant protein
Microbiology and Infectious DiseasesRecombinant proteins as important materials for biomedicinal research, need high level of purity in order to be used in ...Read more
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RNY12 peptidomimetic increases SH-SY5Y Neuronal Survival Comparable to BDNF
Stem cell and Medical ApplicationsBrain-derived neurotrophic factor (BDNF) activates downstream cell signaling pathways through TrkB receptor and triggers...Read more
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Isolation and identification of probiotic bacteria from human milk
Microbiology and Infectious DiseasesBackground: Breast milk is the best nutritional supplement during the first few months of the baby's life. It contains v...Read more
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Relationship between a phenotype and one gene
Medical GeneticsStudy of whole genomes is genomic. The genes contain instructions for protein synthesis that are the functional part of ...Read more
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Molecular mechanism of alpha-2 adrenergic receptors in locus Coeruleus
Medical GeneticsPain is one of the most common forms of psychological stress and the most common phenomenon in medical science. Analgesi...Read more
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Endurance training resulted in significantly greater betatrophin responses compared with resistance training alone, and resistance and endurance exercises combined
Metabolism and Metabolic DiseasesBetatrophin, which recently identified, is a liver and adipose tissue produced hormones that regulates the level of lipi...Read more
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Investigating the Verification of the Personnel Hand Hygiene Dividedly among Five Situations in Intensive Working in Namazi Hospital of Shiraz
Microbiology and Infectious DiseasesHand hygiene behavior divides into two categories: the innate hand hygiene and the selective hand hygiene. The innate ha...Read more
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Effect of Biochanin A on retinal angiogenesis and inflammation in STZ induced diabetic rats
Metabolism and Metabolic DiseasesWithout proper medication for the treatment of diabetic retinopathy (DR), retinal cells become malnourished and degenera...Read more
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The Effect of Vitamin D on Diabetes Mellitus: A Systematic Review
Metabolism and Metabolic Diseases: Diabetes Mellitus is a common metabolic and non-infectious disorder that affects around 346 million people worldwide w...Read more
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Interaction of an anti-cancer drug Crizotinib with serum albumin: A docking study
Cancer; Prevention, Diagnosis and TreatmentCancer treatment is one of the major challenges of medical science today. Among them, lung cancer is a common type of ca...Read more
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HETEROGENEITY OF ESCHERICHIA COLI ISOLATES WITHIN DIFFERENT
Microbiology and Infectious DiseasesAim:Escherichia coli is one of the most important bacterial pathogens causing urinary tract infections (UTIs) . This bac...Read more
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Drafting maggot therapy in personalized cancer therapy
Cancer; Prevention, Diagnosis and TreatmentIn some personalized cancer therapies the elimination of the tumor will be a result of the injection of flesh- eating ba...Read more
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Combinatorial therapy of anti-Treg vaccine associated with anti-tumor DC vaccine in mice tumor therapy
Cancer; Prevention, Diagnosis and TreatmentRegulatory T cells (Tregs) obviously have a crucial role in attenuation of anti-tumor immune responses. Application of r...Read more
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Braest cancer micrometastatic detection in sentinele lymph nodes using molecular marker
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is prevalent malignancy among women in worldwide (1). Molecular diagnosis is recently proposed as a sensit...Read more
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The efficacy of Leptin on physical and psychological stress causing gastric ulcer: Participations of nitric oxide and prostaglandin E2
Nutrition and HealthThe present study aimed to assess the effects of Leptin on physical and psychological stresses inducing gastric ulcer. T...Read more
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Effect of Crocin on mitochondrial biogenesis and Oxidative stress in the Striatum of Cholestatic rats
Medical GeneticsOxidative Stress and increment of Mitochondrial Reactive Oxygen Species (ROS) production that occurs in cholestasis whic...Read more
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Alterations of gyrA in Enterobacteriaceae isolated of urinary tract infection resistance to quinolones antibiotics
Microbiology and Infectious DiseasesUrinary tract infection is one of the most common infections, which if not treated, it can be cause seriouse problem in ...Read more
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Overview the Challenges and Development of regenerative medicine in future
Stem cell and Medical ApplicationsMore than 2000clinical trials relating stem cells, there is not a single clinical difficult that is regularly treated wi...Read more
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Apoptotic and cytotoxic effect of the thiosemicarbazone complex with Zn2+ in K562 cell line
Cancer; Prevention, Diagnosis and TreatmentThiosemicarbazone family is organic compounds with antitumor, antibacterial and antiviral effects. In the present stud...Read more
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The Study of the Frequency of Antibiotic Usage as an Important Factor in Appearing Antibiotic Resistance in All of the Units in Namazi Hospital
Microbiology and Infectious DiseasesAs the unusual increase in using antibiotics has been suggested as an indicative factor in appearing antibiotic resistan...Read more
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Influence of CYP2D6 and CYP3A4 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia and treatment response
Cancer; Prevention, Diagnosis and TreatmentXenobiotic- metabolizing enzymes compose an important line of defence against a variety of carcinogenes and environmenta...Read more
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Effect of marjoram extract on sperm concentration and its survival percentage in oxidative-cadmium stress in adult male rats
Nutrition and HealthNutrition Safety and Health is one of the important factors in fertility.Cadmium as an environmental pollutant by free r...Read more
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Relationship between Hypertension in the First Trimester of Pregnancy with Weight and Height at Birth
Women and Reproductive HealthBackground: Hypertensive disorders with a prevalence of %5-10 are among the main causes of morbidity and mortality in mo...Read more
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Evaluation of Interleukin 10 Gene Promoter Polymorphisms of -592A/C and -1082A/G Region Among Obese Individuals with Type 2 Diabetes in Alborz Province
Metabolism and Metabolic DiseasesToday diabetes is one of the most prevalent noncontagious diseases around the world. There is strong evidence showing in...Read more
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An update review about stem cell therapy for diabetes mellitus
Stem cell and Medical ApplicationsMesenchymal stem cells (MSCs) are the most widely used stem cells of the human body because of successful isolation, and...Read more
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Mesenchymal stem cells enhance the metastasis of cervical cancer cell line, CaSki, in 3D cell culture system
Cancer; Prevention, Diagnosis and TreatmentMesenchymal stem cells, also known as mesenchymal stromal cells (MSCs), are attractive for repair and regeneration of ti...Read more
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Designing and cloning and expression of bean defensin in human embryonic kidney cells and evaluating their antibacterial function
Microbiology and Infectious DiseasesDefensins are among the most important cationic peptides that their presence in a wide range of herbs and animals has be...Read more
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Familial occurrence of Mayer-Rokitansky-Küster-Hauser syndrome in two siblings in Iran
Medical GeneticsFamilial occurrence of Mayer-Rokitansky-Küster-Hauser syndrome in two siblings in Iran Asadi fatemeh 1*, shokouholsa...Read more
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Study of properties of Juglans regia plant on women’s health
Women and Reproductive HealthJuglans regia plant is one of Iranian native plants that some of it’s productive types are in Markazi province. The b...Read more
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New mutation in hotspit region of APC gene in FAP patient in Guilan province
Medical GeneticsFamilial adenomatous polyposis (FAP) is a colorectal cancer predisposition syndrome characterized by the presence of hun...Read more
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The effect of 5μM benzoquinone JAG1 and Wnt5a genes in mesenchymal stem cells(MSCs) found in bone marrow(BM) niche
Stem cell and Medical ApplicationsBenzoquinone(BQ) is one of benzene metabolite after entering body, its prolonged presence in body leads to blood disorde...Read more
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Study genetic susceptibility polymorphisms for chronic lymphocytic leukemia in Iranian population.
Medical GeneticsChronic lymphoid leukemia (CLL) is the most common form of leukemia found in adults. CLL is a monoclonal disorder that w...Read more
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In silico design and analysis of crRNA for post transcriptional regulation of oncogenic miR-128-2 and miR-217 by CRISPR-C2C2 technique.
Medical GeneticsBased on recent studies some microRNAs could have drug resistant effects in turmeric cells during therapy. There are evi...Read more
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Tamoxifen-induced rapid death of GPER positive cell lines by modulating RAS/MAPK signaling pathway
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the most common cancer in women worldwide. Tamoxifen is a nonsteroidal selective estrogen receptor modu...Read more
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Identification of Oral strains of Lactobacillus.species in patients with chronic periodontitis and healthy individuals
Microbiology and Infectious DiseasesOral infections constitute some of the most common and costly forms of infections in humans.Chronic periodontitis has be...Read more
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Gene expression profiling of the 8q22-24 position in human breast cancer: TSPYL5, MTDH, ATAD2 and CCNE2 genes are implicated in oncogenesis, while WISP1 and EXT1 genes may predict a risk of metastasis
Cancer; Prevention, Diagnosis and TreatmentGene expression profiling has been suggested to predict breast cancer outcome. The prognostic value of the 8q22 24 posit...Read more
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Investigation of cytotoxicity, cell cycle and induction of apoptosis by methyl-thiosemicarbazone complex with Cu2+ in K562 cell line
Cancer; Prevention, Diagnosis and TreatmentThiosemicarbazone compounds have previously been considered as a new series of potent apoptosis-inducing agents. In the ...Read more
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Correlation between oral health status and salivary total antioxidant capacity in type 2 diabetes mellitus among Iranian adults
Metabolism and Metabolic DiseasesDiabetes mellitus is a chronic metabolic disease leading to several complications. Among these, dental caries are consid...Read more
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A simple way for extracting singular porphyrin peaks from total fluorescence spectrum of plasma
Metabolism and Metabolic DiseasesPorphyrins are organic compounds formed from the breakdown of hemoglobin. Any disturbance in porphyrins’ level can be ...Read more
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Detection of macrolid and fluoroquinolones resistance among campylobacters isolated from diarrhea patients in Markazi province - 2015
Microbiology and Infectious DiseasesCampylobacter species, especially C. jejuni and C. coli, are the most common bacterial causes of gastroenteritis in huma...Read more
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Performing PGD combined with HLA typing on more than 100 blastomeres
Medical GeneticsPreimplantation genetic diagnosis (PGD) is an option for carrier couples who want to assure their child’s health regar...Read more
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Cytotoxicity study of nanoparticles containing aminoglycosides
Nano-Biotech MedicalAminoglycosides are a bunch of antibiotics that inhibit the synthesis of protein in bacteria and lead to eradication of ...Read more
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Evaluation of the interaction between hemoglobin protein and angiotensin-inhibitory peptide by three-dimensional fluorescence method in the absence and presence of low-frequency electromagnetic fields
Metabolism and Metabolic DiseasesMillion people in worldwide are suffering from high blood pressure and related diseases. Over the past two decades, ther...Read more
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Evaluation of NTT and Double-Test in screening of Down Syndrome
Women and Reproductive HealthPrenatal diagnosis of genetic, congenital and hereditary diseases is the first step to prevent and control these prob...Read more
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Design, modeling and simulation of a novel immunotoxin structure affective against gastrointestinal malignancies
Cancer; Prevention, Diagnosis and TreatmentGastrointestinal malignancies comprise a remarkable proportion of cancer deaths each year. Although many drugs have been...Read more
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Improvement of Prognostic model for breast cancer recurrence by data mining methods
Cancer; Prevention, Diagnosis and TreatmentIn Iran, every year 10,000 people suffer from breast cancer, of which half of them are under the age of 50. The recurren...Read more
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The salivary beta-2microglobulin (β2M) and prostate-specific antigen (PSA) can be used as an alternative to the serum β2M and PSA for diagnosis and monitoring of prostate diseases
Cancer; Prevention, Diagnosis and TreatmentIn recent years, the use of saliva as a specimen, due to its non-invasive and easy access increased. But their roles hav...Read more
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Design, production and purification of polyclonal antibodies against recombinant human erythropoietin antigens for immunological investigation of pharmaceutical and clinical samples
Nano-Biotech MedicalIn this research, the primary antibody against erythropoietin is produced by injecting pure recombinant human erythropoi...Read more
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Electrospun PVA/PVP/chitosan Membrane with Controlled Release of Antibiotics for intraperiodontal pocket drug delivery
Nano-Biotech MedicalGingivitis and periodontitis have become major public health problem in the world. Such growing incidence of periodontit...Read more
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Anti-anxiety effects of sinapic acid in NMRI mice
Nutrition and HealthThe present study investigated the anxiolytic effects of sinapic acid on NMRI mice behavior in the elevated plus-maze (E...Read more
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Mortality effect of Silibinin on the A549 cell line
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the leading cause of cancer death in the world, with 1,375,000 deaths annually. Common chemotherapy such ...Read more
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Production of recombinant Streptococcal pyogenes exotoxin a protein
Medical GeneticsExotoxin A is one of the toxins which produce by group a streptococcuses. This Toxin is a protein soluble substance whic...Read more
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Antibody-drug conjugates; a Novel class of cancer treatment
Cancer; Prevention, Diagnosis and TreatmentOne of the most effective therapeutic agents used in targeted cancer therapies is antibody. Due to lack of permeability ...Read more
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evaluation of anti-mullerian hormone in daughters of women with polycystic ovary syndrome
Women and Reproductive HealthPolycystic Ovary Syndrome(pcos) is one of the most common endocrine diseases among women during their fertility years . ...Read more
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MEDITERRANEAN DIET AND METABOLIC SYNDROME IN DIABETIC SUBJECTS
Metabolism and Metabolic DiseasesType 2 diabetes mellitus (T2DM) increases cardiovascular diseases risk and is a key component of metabolic syndrome (Met...Read more
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Thiolated chitosans development and in vitro evaluation of apermeation enhancing oral drug delivery system
Nano-Biotech MedicalThis study investigated the in vitro release of Vancomycin and Amphotericin B fromnovel mocuadhesive chitosan nanofibers...Read more
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Potentiation of mitomycin C-induced apoptosis by lithium chloride in MDA-MB-231 breast cancer cells
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the principle cause of cancer mortality in females. Mitomycin C (MMC), as a potent antitumor drug, is u...Read more
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Hepatoprotective effects of magnesium sulfate on pentylenetetrazol-induced seizures in male Wistar rats
Nutrition and HealthMagnesium is the second most abundant cation (after potassium) in the cell and plays an important role in various biolog...Read more
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Dendrosomal curcumin nanoformulation modulate apoptosis-related genes and protein expression in hepatocarcinoma cell lines.
Nano-Biotech MedicalIntroduction: The side-effects observed in conventional therapies have made them unpromising in curing Hepatocellular c...Read more
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Perineal massage during pregnancy and perineal safety during childbirth
Women and Reproductive HealthIntroduction: Women frequently suffer from perineal trauma during childbirth, especially during the first childbirth. ...Read more
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Experimental and theoretical investigation on Mandelic acid (R, S) enantioselective separation using Vancomycin chiral column in high performance liquid chromatography
Nano-Biotech MedicalNowadays, antibiotic chiral columns can be used in various chromatography separations. The high potential of these compo...Read more
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The effects of sodium butyrate on the expression of HDAC8 gene in HT-29 colorectal cancer cell line
Cancer; Prevention, Diagnosis and TreatmentSodium butyrate (NaB) is a potent growth inhibitor and initiates cell differentiation for many cell types in vitro. In t...Read more
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Lack of association between TNF-α rs1800629 polymorphism and Hepatocellular Carcinoma: a meta-analysis
Medical GeneticsTumor necrosis factor a (TNF-α) is a pleiotropic cytokine which can regulate a wide variety of cellular responses. Low ...Read more
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Role of Potential tumor marker in several cancer: Diagnostic and Treatment
Cancer; Prevention, Diagnosis and TreatmentTumor markers are substances produced by the tumors or by other cells of the body in response to cancer. They are produc...Read more
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Molcular Detection of Mupirocin Resistance in Staphylococcus aureus
Microbiology and Infectious DiseasesStaphylococcus aureus has become the most common cause of hospital acquired infections over the last few decades. The ba...Read more
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Investigation of mutations and polymorphisms in exon 11, 12, 22 and 23 in Non Caucasian cystic fibrosis patients from the north of Iran
Medical GeneticsCystic fibrosis (CF) is the most common autosomal recessive disease in Caucasians, caused by mutation in cystic fibrosi...Read more
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Additive Cytotoxic Effect of Apoptin and Chemotherapeutic Agent Docetaxel on LNCaP Cell Lines
Cancer; Prevention, Diagnosis and TreatmentUnfortunately although chemotherapy is primary therapy for most types of advanced prostate cancer, conventional chemothe...Read more
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The nutritional benefits of Pistacia atlantica
Nutrition and HealthPistacia Atlantica Mutica is a genus of the family Anacardiaceae which consist of different parts such as fruit, leave a...Read more
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Pregnancy management in Iranian Traditional Medicine
Women and Reproductive HealthManaging complications in pregnancy is so important cause of sensitive situation of the mother and the fetus. Physicians...Read more
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Therapeutic effect of Human Tumor Necrosis Factor Receptor-2 on collagen -induced arthritis in Balb/c mice
Metabolism and Metabolic DiseasesRheumatoid arthritis (RA) is a chronic, systemic, immune-mediated inflammatory disease associated with decreased life ex...Read more
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the effect of crocin on forgetfulness caused by cholestasis in male rats(behavioral , biochemical and genetical )
Metabolism and Metabolic Diseasescholestasis is a condition in which the bile ducts that carry bile from the liver to the intestine to dispose, is blocke...Read more
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Design and cloning of tanatin peptide in Pichia.pastoris and evaluation of its antifungal activity
Microbiology and Infectious DiseasesNowadays, control of fungal infections is one of the most important goals in the field of health. Therefore, developing ...Read more
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Investigation of C-582 A>G polymorphism at beta globin cluster gene in beta-thalassemia patients
Medical GeneticsThalassemia is the most prevalent monogenic disorder worldwide resulting from the inappropriate production of heme. pati...Read more
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An in vitro study on the cytotoxicity of anticancer drug Mitoxantrone on hematopoietic stem cells of bone marrow
Cancer; Prevention, Diagnosis and TreatmentMitoxantrone (Novantrone®; dihydroxyanthracenedione) is a synthetically designed antineoplastic agent and structurally ...Read more
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Investigation of A New Paclitaxel Nano Niosomal formulation and Biological Evaluation of Entrapped Paclitaxel on breast cancer cell line
Nano-Biotech MedicalRegarding that the breast adenocarcinoma is the most widespread disease among women, paclitaxel, an anti-cancer drug, co...Read more
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Rapid and cost effective method for the purification of DNA from Streptococcus mutans and other oral microorganisms
Microbiology and Infectious DiseasesOver 325 bacterial species have been cultured from dental plaque. Not all species can be cultured routinely. Thus, consi...Read more
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BsmI (rs1544410) polymorphism of vitamin D receptor gene modulates improvement of vitamin D status in overweight women with hypovitaminosis D
Nutrition and HealthThe aim of the present study was to evaluate the possible influence of BsmI (rs1544410) polymorphism of vitamin D recept...Read more
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Investigating the presence of chemical compounds in pineapple
Cancer; Prevention, Diagnosis and TreatmentPineapple is a member of the Ananasian family, it is a sub-tropical fruit. It has many chemical compounds that are impor...Read more
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Snake venom: an anticancer agent in immunotoxin therapy
Cancer; Prevention, Diagnosis and TreatmentCancer is the second leading cause of death worldwide. Therefore, many studies are underway to innovate more efficient t...Read more
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Inhibition of cell growth in HCT-116 human colorectal cancer cell line by sodium butyrate, a HDAC inhibitor
Cancer; Prevention, Diagnosis and TreatmentSodium butyrate (NaBu), a histone deacetylase (HDAC) inhibitor, is the byproduct of anaerobic microbial fermentation ins...Read more
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The effects of preconditioning mesanchymal stem cells with hydrogen peroxide and serum deprivation on cell viability and apoptosis.
Stem cell and Medical ApplicationsIt is known that application of mesenchymal stem cells is an effective treatment in many diseases. Despite of cell thera...Read more
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Identification and Cloning of Plasposon Insertion Site in Four Mutants of Pseudomonas Gingeri Deficient in White Line Reaction
Microbiology and Infectious DiseasesAntibiotic resistance is an important concern in the world and also in Iran. Identifying new antimicrobial strategies to...Read more
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Evaluation of cytotoxicity of aqueous-ethanolic extract of pineapple on ovarian cancer cells (A2780 cell line)
Cancer; Prevention, Diagnosis and TreatmentToday, the global trend towards the use of herbal medicines for treating diseases has tended, while developed countries ...Read more
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Non-muscle Myosin Heavy Chain 9 Gene (MYH9) Polymorphism (rs4821481) is Associated with Urinary Albumin Excretion in Iranian Diabetic Patients
Medical GeneticsMyosin heavy chain 9 (MYH9) gene polymorphisms have been implicated in a different type of renal disease as well as neph...Read more
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Synthesis of pH-sensitive micelles based on F127-Dox conjugated for drug delivery to cancer cells
Nano-Biotech MedicalA variety of nano-systems constituted by polymer–drug conjugates have been designed to overcome its shortages on water...Read more
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Effect of letrozole as alternative aromatase inhibitor on development of ovarian follicles and uterine changes in adult NMRI mice strain and their infants
Microbiology and Infectious DiseasesLetrozole is used as an aromatase inhibitor, to increase ovulation induction. This drug is usually prescribed for patien...Read more
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Molecular monitoring of Chronic Myeloid Leukemia in Chronic Phase (CML-CP)
Medical GeneticsQuantification of the BCR-ABL transcript is recommended to follow-up CML patients that treated by Imatinib mesylate (IM)...Read more
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Association Chlamydia trachomatis infection and TNFα -308 polymorphism in abortion
Microbiology and Infectious DiseasesSeveral bacterial infections such as Chlamydia trachomatis and host genetic background, including TNFα SNP polymorphism...Read more
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Eradication of Cancer Stem Cells through microRNAs: a conceptual view
Cancer; Prevention, Diagnosis and TreatmentmicroRNAs (miRNAs), as 19-24 nucleotides endogenous non-coding RNAs, are involved in the most cellular processes playing...Read more
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Blocking of vascular endothelial growth factor signaling through design of bi-specific single domain antibody
Nano-Biotech MedicalOver-expression of vascular endothelial growth factor (VEGF) leads to the proliferation and neovasculature of cancer cel...Read more
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Toll-like receptor 4 mediates cross-talk between peroxisome proliferator-activated receptor γ and nuclear factor-κB in mouse melanoma (B16F10) in vitro
Cancer; Prevention, Diagnosis and TreatmentThere is increasing evidence that chronic activation of nuclear factor-κB (NF-κB), which is an essential signaling pat...Read more
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Cancer Stem Cell Therapy Based on Nanostructure Drug Vehicle, PMBN-IL3-GA
Nano-Biotech MedicalTo overcome difficulty of cancer treatment by conventional chemotherapy methods, the targeting drug delivery based on Na...Read more
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Qualitative and quantitative evaluation of airborne microorganisms and the concentrations of particulate and respirable matter causing from dust storm in the air of Ilam city: cross sectional study
Microbiology and Infectious DiseasesIntroduction: In recent years, dust storms frequently arrived to have large areas of the western half of Iran. Dust part...Read more
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Detection of Borrelia microti in blood samples spotted on DNA Banking Card by using Loop-Mediated Isothermal Amplification (LAMP)
Medical GeneticsTick-borne relapsing fever (TBRF) is an endemic disease in Iran, with more 100 annual cases. The glycerophosphodiester ...Read more
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Effect of vitamin E on liver index enzymes in normal and CCl4-intoxified male Wistar rats
Nutrition and HealthVitamin E is the key lipid-soluble antioxidants in humans. Vitamin E supplementation was effective in decreasing markers...Read more
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Combination of ultrasonic waves and dynamic shear stress by design of a novel perfusion bioreactor for 3D bone tissue engineering
Stem cell and Medical ApplicationsIt is shown that mechanical loading by ultrasound enhanced cell proliferation and differentiation. The aim of present st...Read more
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Chimeric Antigen Receptors (CARs) as a powerful approach for cancer therapeutics
Cancer; Prevention, Diagnosis and TreatmentT-cells have the potential to extirpate abnormal cells. The genetic modification and characterization of T-cells with ch...Read more
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the role of genetics in diabetes and its complications
Medical GeneticsThe purposes of writing this article are the significant role of genetics in the onset of diabetes, hoping to be treated...Read more
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Assessment of the dietary intake of Vitamin D and Blood pressure in Elderlies with health care
Nutrition and HealthPopulation studies have demonstrated that there is an inverse association between dietary intake of vitamin D and incide...Read more
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Prevalence of beta-lactam resistant isolates of Enterobacteriaceae in clinical specimens
Microbiology and Infectious DiseasesBackground: The emergence of extended-spectrum beta-lactamase (ESBL) producing isolates of Enterobacteriaceae has impor...Read more
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Autism spectrum disorder (ASD) and cancer: both share same genes but different outcomes.
Medical GeneticsAutism spectrum disorder (ASD) is a neurodevelopmental disorder and it is characterized by social and communication prob...Read more
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Evaluation of nitrate and nitrite content in meat and meat products and their role of these substances in carcinogenesis
Cancer; Prevention, Diagnosis and TreatmentBecause of N-nitrous compounds formation in meat and meat products, There is a direct correlation between high consumpt...Read more
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Polymorphisms evaluation of the thiopurine S-methyltransferase gene among the Iranian acute lymphoblastic leukemia population
Medical GeneticsThiopurine S-methyltransferase (TPMT) is a cytosolic enzyme which catalyzing the S-methylation of 6-mercaptopurine and...Read more
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Comprehensive databank of Iranian patients with Noonan syndrome
Medical GeneticsNoonan syndrome (NS) (OMIM 163950) considered as a relatively common (1/1000-2500), developmental, multi-organ and compl...Read more
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Investigating the antitumor activity of PNU-74654 as Wnt/β-catenin inhibitor, alone or in combination with gemcitabine in MiaPaCa-2 pancreatic cancer cell
Cancer; Prevention, Diagnosis and TreatmentWnt/beta-catenin pathway is one of the key dysregulated pathways in several malignancies, including pancreatic cancer (P...Read more
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In silico evaluation of anti-retroviral effects of lactoferrin from different species
Microbiology and Infectious DiseasesLactoferrin (LF) is an iron binding glycoprotein that is present in body fluids and mucosal secretions. Antimicrobial pr...Read more
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Human reovirus destroys liver cancer cell line (Huh-7)
Cancer; Prevention, Diagnosis and TreatmentThe Huh-7 cell line was derived from a liver tumor in a 57-year-old Japanese male patient in 1982. Hepatocellular carcin...Read more
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Ginseng For Improving The Quality Of Life In People With Cancer and Fatigue- A Systematic Review
Cancer; Prevention, Diagnosis and TreatmentBackground and purpose: An important issue in cancer health care is the improvement in quality of life (QoL). Physicians...Read more
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Effect of folic acid supplementation on acute effects of trimethoprim/sulfamethoxazole on histopathological changes in the testes of adult male rats
Stem cell and Medical ApplicationsMale infertility has been reported following long-term sulfasalazine use for ulcerative colitis treatment. However, the ...Read more
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Poly(A)-tail shortening Length: an Alternative Epigenetic Mechanism for Translational Control of Oncogenes
Medical Genetics: mRNA poly(A) tails in 3'UTR is important for its stability and translation. t is observed Poly(A) tails is dynamic and...Read more
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Anticancer Application of Camel Milk: A Review of Recent Research
Cancer; Prevention, Diagnosis and TreatmentBecause of importance of cancer and the side effects of existing therapies, it is essential to find new therapeutic stra...Read more
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Study of DNA binding and cytotoxic activity of a benzochromene derivative
Cancer; Prevention, Diagnosis and TreatmentDNA is currently a target for some of the drugs used in cancer therapy. Among the various treatment strategies for remov...Read more
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Lack of association between Hypoxia Inducible Factor rs11549465 polymorphism and Preeclampsia
Medical GeneticsPre-eclampsia (PE) is an obstetric disorder that may result inmaternal and neonatal mortality and morbidity. Placental h...Read more
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Frequency of TEM and SHV genes in the strains of Acinetobacter producing broad-spectrum isolated ß-lactamases from Zahedan patients by PCR method
Microbiology and Infectious DiseasesAcinetobacter baumannii is one of the most important factors in hospital infections, and its Colonization rate in hospit...Read more
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Comparison of Antibacterial Activity of Essential Oil of Varieties of Calendula Plant from Varamin (Iran) on Escherichia coli and Staphylococcus aureus
Microbiology and Infectious DiseasesUncontrolled use of conventional antibiotics and synthetic antibacterial medicine has led to the proliferation of microb...Read more
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Using micronuclei assay in cancer treatment
Medical GeneticsCancer is one of the leading causes of illness and mortality worldwide, after cardiovascular disease. There are differen...Read more
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Prevalence of septicemia in Intasive care unit and Internal medicine wards patients in Rajaee Hospital of Karaj
Microbiology and Infectious DiseasesSepticemia or blood infections is One of the most important causes of death in patients hospitalized in different parts...Read more
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The role of long non-coding RNAs in hematologic malignancies
Cancer; Prevention, Diagnosis and TreatmentLong noncoding RNAs(lncRNAs) are a novel heterogeneous group which refer to non-coding RNA molecule ranging in length fr...Read more
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Silencing of TIM-3 expression by miR-326 affects apoptosis and proliferation of human HL-60 leukemia cell line
Cancer; Prevention, Diagnosis and TreatmentLeukemia Stem Cells (LSCs) are the main reason for drug-resistance and disease relapse in Acute Myeloid Leukemia (AML). ...Read more
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Stress-induced immobility in male and female rats and its effects on offspring numbers, sex ratios and sexual hormones
Women and Reproductive HealthStress-induced immobility inhibition of reproductive functions and can effect on sexual hormones. Increasing/decreasing ...Read more
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Evaluation of serum lipid profiles and oxidative stress indices in sprayer workers
Metabolism and Metabolic DiseasesDirect or indirect contact with pesticides and toxins leads to some biochemical changes, including increasing the produc...Read more
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The effect of 5μM benzoquinone on CXCL12 and KITLG genes in mesenchymal stem cells found in bone marrow niche
Stem cell and Medical ApplicationsChronic exposure to benzene is known to damage the BM resulting in development of different types of leukemia. Extrinsi...Read more
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Impact of CYP3A5 and CYP3A4 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia and treatment response
Medical GeneticsCYP3A5 and CYP3A4 are the members of the CYP3A gene family which metabolizes 50% of therapeutic drugs and steroid hormon...Read more
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Knowledge and Practice of Breast Self-Examination Among Female Students in Sari Islamic Azad University in 2015-2016
Cancer; Prevention, Diagnosis and TreatmentBreast self-examination (BSE) is one of the ways of prevention and early detection of breast cancer. The aim of this stu...Read more
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Silibinin Inhibits miR-17 in Co-cultured HUVECs with A549 Cell Line
Cancer; Prevention, Diagnosis and TreatmentMicroRNAs are involved in different biological processes including cell proliferation and apoptosis, the two intimately ...Read more
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The Relationship between STR-PCR Chimerism Analysis and Chronic GvHD Following Hematopoietic Stem Cell Transplantation
Cancer; Prevention, Diagnosis and TreatmentGraft-versus-host disease (GvHD) is one of the serious complications of HSCT. Its prevalence has been reported as 20-50 ...Read more
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Surface modification of Chitosan nano-fiber by cold atmospheric plasma
Nano-Biotech MedicalSurface modification is the act of modifying the surface of a material by bringing physical, chemical or biological char...Read more
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Cytotoxic activity of Berberine on the growth of breast cancer cell line (MCF-7)
Cancer; Prevention, Diagnosis and TreatmentMuch research has been conducted on the benefits of various phytochemicals in many herbs, fruits and vegetables and thei...Read more
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Preparation and optimization of chitosan nanoparticles containing vancomycin
Nano-Biotech MedicalRecently, some novel drug delivery systems were designed to control drug release. The using of polymeric nanoparticles a...Read more
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NEW CONCEPTS IN THE IMMUNOPATHOGENESIS OF MULTIPLE SCLEROSIS
Medical GeneticsMultiple sclerosis (MS) is a chronic disorder of the central nervous system characterized by autoimmune inflammation, de...Read more
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Genetic variations of Cholesteryl ester transfer protein and diet interactions in relation to lipid profiles and coronary heart disease: A systematic review
Nutrition and HealthThe number of investigations on diet–genotype interactions in the prevention or treatment of dyslipidemia have increas...Read more
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A review: Runt-related transcription factor 2 (RUNX2) and its signaling pathways in cardiovascular complications.
Metabolism and Metabolic DiseasesVascular calcification (VC) is a process similar to bone mineralization. VC has been observed in chronic kidney disease,...Read more
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Association between mtDNA D-Loop Mutation and secondary lung cancer
Cancer; Prevention, Diagnosis and TreatmentLung cancer is one of the leading cause of cancer death in the world. The aim of this study was to determine deletions ...Read more
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COMPARATIVE STUDY OF OLERACEIN E AND OLERACEIN L EFFECTS ON ANTI OXIDANT ACTIVITY, ANTI DIABETIC INDICATORS AND DAMAGE BIOMARKERS LEVELS IN PANCREATIC CELL LINE
Nutrition and HealthThe medicinal plants have valuable biochemical effects. The aim of this study was to assess the effects of Oleracein E a...Read more
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BRCC2 gene inhibits lung cancer cell proliferation and invasiveness in vitro and in vivo:Prospect for gene therapy
Cancer; Prevention, Diagnosis and TreatmentLung cancer is one of the major causes of cancer related death worldwide .Despite recent improvements, resistance to con...Read more
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Canavan disease: clinical and molecular review
Medical GeneticsCanavan disease is a rare autosomal recessive disorder that predominantly affects the central nervous system with white ...Read more
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Optimization of the best concentration of Aloe vera extract for treating gastric cancer cells in order to reduce HER-2 gene expression
Cancer; Prevention, Diagnosis and TreatmentHER2 is a glycoprotein that has tyrosine kinase activity and plays an important role in guiding growth signals. Its expr...Read more
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Cloning, expression and functional assay of bacterial Uricase, a medical enzyme for the treatment of chronic gout
Metabolism and Metabolic DiseasesUricase, which is originated from a variety of organisms including bacteria, is an important agent for tracing of Uric A...Read more
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Discrimination of Leishmania species by Arginine permease gene AAP3as a suitable molecular tool for detection and genetic proximity analysis
Microbiology and Infectious DiseasesLeishmaniasis presents itself in different clinical manifestations such as: visceral Leishmaniasis, Cutaneous Leishmania...Read more
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Comparison of in vitro survival of mononuclear cells derived from B-CLL patients with or without BAFF & APRILL cytokines
Cancer; Prevention, Diagnosis and TreatmentThis article studies the antiapototic effect of cytokines BAFF & APRIL on the survival of mononuclear cells derived ...Read more
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The levels of VDBP in patients with chronic rhinosinusitis with polyposis
Medical GeneticsChronic rhinosinusitis (CRS) is a prevalent disease which is characterized by chronic inflammation of the nasal mucosa ...Read more
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The comparative proteomic pattern study of albumin fraction in type I Gaucher Patients with 2 Dimensional Electrophoresis
Metabolism and Metabolic DiseasesThe gaucher disease is the most common type of lysosomal storage diseases that, particularly affects the macrophage cell...Read more
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EFFECT OF CHRYSIN NANO-PARTICLES TREATMENT ON ESTROGEN RECEPTORS EXPRESSION LEVELS IN BREAST CANCER CELL LINE
Nano-Biotech MedicalBreast cancer (BC) is increasing in the developing countries. Estrogens are supposed to play roles in BC initiation and ...Read more
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The effects of nano-liposomes containing curcumin on the lung cancer cell line.
Nano-Biotech MedicalLung cancer is one of the most common and malignant cancer in both sexes. The prevalence and spread of cancer in iran an...Read more
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Astaxanthin decreases cell viability in MDA-MB-231, but not in non-tumorigenic human breast cell line MCF 10A
Cancer; Prevention, Diagnosis and TreatmentConsidering the high prevalence of breast cancer in Iran, its rising incidence, and the high mortality rate of patients ...Read more
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Involvement of Mu Opioid Receptor Signaling in the Protective Effect of Opioid against 6-Hydroxydopamine-Induced SH-SY5Y Human Neuroblastoma Cells Apoptosis
Cancer; Prevention, Diagnosis and Treatment1. Introduction arkinson’s disease (PD) is a neurodegenerative disease caused by losing dopaminergic neurons of the ...Read more
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Finding a new approach for Treatment of osteoporosis with trace element and antioxidant in rat animal model
Metabolism and Metabolic DiseasesOne of the most common bone metabolic and endocrinal disorders is osteoporosis. It is defined by progressive bone loss, ...Read more
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Evaluation of nitrosative stress in sprayer workers
Metabolism and Metabolic DiseasesAgricultural pesticides have an important impact on human health and farmers are people who are more exposed to pesticid...Read more
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In silico epitope prediction and modeling for agent of smallpox and molecular docking for epitope-MHCⅠ receptor
Medical GeneticsAlthough Variola and Vaccinia viruses have been Eradicated but still smallpox can be a serious problem for Societies. H3...Read more
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Frequency of Binding Site at C-Terminal of Helicobacter Pylori CagA Separated from Gastric Tissue Biopsy of Patients with Gastroduodenal Disorders in Shafa Hospital in Khorramabad
Microbiology and Infectious DiseasesHelicobacter pylori (H. pylori) is a gram-negative, microaerophilic bacterium in gastric mucosa. It has a helical shape...Read more
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Evaluation of Salmonella.spp in Synovial Fluids of Arthritis Patients by Molecular Method
Microbiology and Infectious DiseasesArthritis is an inflammation of the joints. This complication is often accompanied by pain, swelling, stiffness and heat...Read more
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Crispr/cas9 a New Approach to Genome Engineering
Medical GeneticsIn 1987, scientists found an acquired immune system in E.coli genome, included series of short repetitive interspaced pa...Read more
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The effect of aerobic training with pomegranate juice on glycemic control and lipid profile women with type 2 diabetes
Metabolism and Metabolic DiseasesType 2 diabetes is a common metabolic disease, which is associated with obesity and immobility. The studies have shown t...Read more
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Microencapsulation and double-coating of probiotic bacteria for enhancement of their viability and targeted delivery
Nutrition and HealthThe purpose of this study was to assess the protecting character of double coated beads of alginate-chitosan-Eudragit S1...Read more
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Survey of the Relationship between Two Polymorphisms at Position T677C and C1298A in MTHFR Gene with ADHD in Tehran Children
Medical GeneticsAttention deficit hyperactivity disorder is one of the most common behavioral disorders in children, which is associated...Read more
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Down regulation of Bcl2 and up regulation of Bax during 2-NDC mediated apoptosis in Acute Promyelocytic Leukemia NB4 cells
Cancer; Prevention, Diagnosis and TreatmentDithiocarbamates have been known as important chemical synthetic compounds for treatment of cancer....Read more
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Recombinant fibroin containing the RGD motif enhances limbal mesenchymal stromal cell adhesion and proliferation
Stem cell and Medical ApplicationsAt the periphery of the cornea, in a region called the limbus, exists a population of stromal progenitor cells termed li...Read more
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Molecular Cloning of Clostridium perfringens Type D & Clostridium septicum vaccine strain epsilon alpha fusion gene in E. coli
Medical GeneticsDesigning and producing a proper fusion construction is the most important problem of producing large quantities of fu...Read more
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Can air pollution impact of sperm parameters? A meta- analysis
Women and Reproductive HealthAir pollution is common in all countries and affects reproductive functions in men and women. It particularly impacts sp...Read more
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Modeling of cancer drugs on the route JAK-STAT in cancer stem cells
Cancer; Prevention, Diagnosis and TreatmentAbstract JAK/STAT pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for dev...Read more
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Association of rs699 Polymorphism in AGT Gene with Coronary Heart Disease Risk
Medical GeneticsThe rs699 transition in human angiotensinogen (AGT) gene, result in methionine (M) to threonine (T) substitution at codo...Read more
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CLONING AND EXPRESSION OF an antibody fragment (scFv) against PcrV protein of Pseudomonas aeruginosa in fed-batch cultivation mode
Microbiology and Infectious DiseasesPseudomonas aeruginosa is a major cause of hospital-acquired infections, particularly in mechanically ventilated patient...Read more
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Neuroprotective nature of adipokine resistin in the early stages of focal cerebral ischemia in a stroke mouse model
Metabolism and Metabolic DiseasesThe goal of the present study was to test the dose-dependent and time-dependent effects of mouse recombinant resistin in...Read more
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Prevalence of Pediculus capitis among School Children in the Eastern Area of Ahvaz, Southwestern Iran
Microbiology and Infectious DiseasesHead lice are wingless, obligate ectoparasites of humans, which affect millions of children worldwide, especially those...Read more
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Investigation of synergies effects of albumin- amino penicillin on Staphylococcus aureus MRSA
Nano-Biotech Medicalduring the recent decades, Nanotechnology has entered the field of drug industries and importance of nano-drugs in curin...Read more
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Investigating the incidence of cardiovascular in patients with ercutaneous coronary interventionin Bandar Abbas Shahid Mohammadi Hospital
Metabolism and Metabolic DiseasesPCI(Percutaneous coronary intervention) is one of the most common mode of re vascularization. so According to the impo...Read more
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Naltrexone changes the expression of lipid metabolism-relatedproteins in the endoplasmic reticulum stress induced hepatic steatosis in mice
Metabolism and Metabolic DiseasesEndoplasmic reticulum (ER) stress is closely associated with several chronic diseases such as obesity, atherosclerosis, ...Read more
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Association of selenoprotein S expression and its variants with metabolic syndrome in subjects with cardiovascular disease
Metabolism and Metabolic DiseasesSelenoproteins S (SELS or VIMP) may regulate cytokine production, and thus play a key role in the control of the inflamm...Read more
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Association study of rs369770942 of neuregulin1 gene 3'UTR with schizophrenia
Medical Genetics: Schizophrenia is a mental disorder and affects approximately 1% of global population. This study suggests that rs36977...Read more
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Structural Study of Lysozyme upon Interaction with Plasmonic gold Nanoparticles
Nano-Biotech MedicalRecent advances in nanotechnology have encouraged scientists to design hybrid systems of nanoparticles and biological ma...Read more
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Effect of EMF on Semen TBARS Concentration
Women and Reproductive HealthElectrical instruments in human life by development of applications causes new biological phenomenon in this century. Ne...Read more
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The prevalence of adeABC encoding genes among Acinetobacter baumannii carbapenem resistant clinical isolates.
Microbiology and Infectious DiseasesAcinetobacter baumannii is the important cause of nosocomial infections worldwide due to its propensity to rapidly acq...Read more
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Cloning and expressing the chimeric peptide lactoferricin-lactoferampin camel in Lactococcus lactis for promising as a candidate for oral medication
Nutrition and HealthLactococcus lactis is known as probiotics due to its lack of harmful toxins. Because of its high growth potential and re...Read more
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Investigating the effects of saffron and melatonin with radiotherapy on viability of Hela cells
Cancer; Prevention, Diagnosis and TreatmentNowadays, a lot of people in the worldwide dead because of cancer. Despite much research in this area, there is still no...Read more
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Blood porphyrin fluorescence peaks and its diagnostic value for early colorectal cancer (CRC) detection
Cancer; Prevention, Diagnosis and TreatmentPorphyrins are precursors of Heme metabolism. Any metabolic disorder like cancer can highly affect their level. Since th...Read more
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Some candidate Biomaterials for Amniotic Membranes (AM) Regeneration: a review
Stem cell and Medical ApplicationsAmniotic Membranes (AM) wich form the amniotic sac filled by amniotic fluid and completely surrounds the embryo/fetus. I...Read more
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Design And Application Of A Loop-Mediated Isothermal Amplification (LAMP) Assay For Detection Of Tick Borne Relapsing Fever
Medical GeneticsTick borne relapsing fever (TBRF) caused by Borrelia microti is transmitted via bites of the soft tick Ornithodoros erra...Read more
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Role of MicroRNAs in Multiple Sclerosis
Medical GeneticsMultiple sclerosis (MS) is an autoimmune neurodegenerative disease in which the body’s natural defense system attacks ...Read more
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The relationship between serum creatinine and creatinine clearance with the occurrence and severity of coronary artery disease
Metabolism and Metabolic DiseasesCardiovascular diseases are thought to be the most important reason of mortality around the world. Among them coronary a...Read more
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Has Clusterin gene a role in spermatogenesis?
Women and Reproductive HealthAzoospermia is a male disorder observed in 1% of the general population and in 10–15% of infertile men that is defined...Read more
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Kisspeptin decreases mean serum adiponectin concentrations in rats
Women and Reproductive HealthKisspeptin/GPR54 signaling system is one of the most important pathways of hypothalamus for regulating reproductive proc...Read more
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Determination of GPR55 overexpression by quantitative real-time PCR as a biomarker for skin SCC detection
Cancer; Prevention, Diagnosis and TreatmentChronic wounds resemble the wounds arising with skin squamous cell carcinoma (SCC). Since they are cancerous, they shoul...Read more
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TP53 hotspot mutations and expression of c-Myc oncogenes in astrocytoma and meningioma
Medical GeneticsMost studies have shown that there are association between the development and malignancy of brain tumors and tumor supp...Read more
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Normal body mass index as a protective factor for osteoporosis after menopause
Nutrition and HealthIncreased body weight is positively related to higher bone mineral density (BMD) in both pre- and post-menopausal women....Read more
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Evaluation of Catalase (CAT) expression in Acute Myeloid leukemia Patients
Cancer; Prevention, Diagnosis and TreatmentAcute myeloid leukemia is a heterogeneous neoplastic malignancy, that despite considerable progress in many of its molec...Read more
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MUC21 as a suitable candidate for immunotoxins development for targeting esophageal cancer
Cancer; Prevention, Diagnosis and TreatmentEsophageal cancer is the world's eighth most common cancer and the sixth most common cause of cancer death in the world....Read more
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Enrichment analysis of hsa-miR-320b-1 most related pathways in cancer
Cancer; Prevention, Diagnosis and TreatmentIntroduction: Cancer is a complex disease in which the expression of the gene is unbalanced. MicroRNAs are a group of no...Read more
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Expression of NAV2 correlated with Change of tumor size in breast cancer patients
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the first leading cause of cancer death among Iranian women and the second worldwide. This type of canc...Read more
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Relation between Resilience and Psychiatric Disorders in Patients with Aids in Bandar Abbas Center for Behavioral Diseases
Nutrition and HealthThe AIDS process is very complex and can significantly affect the physical, social, spiritual and psychological health o...Read more
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Explaining Women's Views on Cervical Cancer: A Qualitative Study
Cancer; Prevention, Diagnosis and TreatmentCervical cancer is the second most common cancer in the world , Which, if detected and treated at early stages, is almo...Read more
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PGD strategy in helping an obligate Hemophilia A carrier woman to have healthy children
Medical GeneticsPreimplantation genetic diagnosis (PGD) is a strategy that has been applied for high-genetic-risk couples with a known g...Read more
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Development of a chemiluminometric lateral flow biosensor for sensitive detection of Escherichia coli
Microbiology and Infectious DiseasesPaper based nucleic acid testing (NAT) has attracted significant interest in point of care diagnostic field. Lateral flo...Read more
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Bioinformatics evaluation of hsa-miR-548g related to single nucleotide polymorphism (rs1803622) of GAPDH gene in patients suffering from breast cancer
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is one of the most prevailing cancer among females. GAPDH gene is located on chromosome l on position of G...Read more
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Integrin Beta-3 gene polymorphism and risk for myocardial infarction in premature coronary disease
Medical GeneticsContradictory results have been obtained regarding the role of integrin, beta 3 (ITGB3) gene polymorphisms in occurrence...Read more
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Design, synthesis and application of conjugated gold nanoparticles in photodynamic therapy
Nano-Biotech MedicalPhotodynamic therapy (PDT) has been developed as a novel method for cancer therapy. PDT involves the combined use of a p...Read more
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Effect of LPS on regulatory T cell induction in peripheral blood mononuclear cells of endometriosis patients
Women and Reproductive HealthEndometriosis is an estrogen-dependent chronic inflammatory disease affecting women of reproductive age. Regulatory T ce...Read more
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study of promoter methylation status of pax5 gene in patients with gastric cancer
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is the fifth leading cause of cancer and is also the third leading cause of death in the world .Although ...Read more
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Effect of intracerebroventricular injection of Adenosine on food and fat intake in neonatal chicks
Nutrition and HealthThe present article was aimed to clarify the role of central Adenosine on food intake in neonatal chicks. Adenosine is n...Read more
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Fertilization rate would be improved after vitrification of immature mouse oocytes
Women and Reproductive HealthVitrification of oocyte is a promising technique to preserve fertility in different species, but it has deleterious effe...Read more
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The effect of mouse recombinant resistin on blood- brain barrier permeability, MDA content and apoptosis in the early stages of focal cerebral ischemia in a stroke mouse model
Metabolism and Metabolic DiseasesThe aim of this study was to evaluate the dose-dependent effects of mouse recombinant resistin on blood-brain barrier(BB...Read more
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Evaluation of the HLA-B46 Allelic frequency in the patients with spondyloarthritis syndrome in zanjan province
Medical GeneticsSpondyloarthritis is a group of multi-systematic disorders that has been created by spinal features, peripheral jointsan...Read more
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Evaluation of the HLA-B07 Allelic frequency in the patients with spondyloarthritis syndrome in zanjan province
Medical GeneticsIn 1974 Moll and colleagues established the concept of a group of inter-related disorders originally termed seronegative...Read more
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A technical overview on the neuronal dysfunction induced by heat stroke on the C57 mice models
Medical GeneticsHeat is an environmental hazard that via increasing core body temperature leads to innate stress with pathological and p...Read more
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Investigating the role of Nanodrugs in the treatment of Candida and Aspergillus infectons
Microbiology and Infectious DiseasesInvasive fungal infections are a major problem for immunocompromised patients in intensive care units. Morbidity and m...Read more
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Interference of Dopamine D2 Receptors and Food Restriction on Changing Anxiety Behavior and Serum Biochemical Factors in Adult Male Rats
Nutrition and HealthBackground: Food restriction (FR) and dopaminergic system affect on anxiety behavior, but it has not been determined the...Read more
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Synthesis and characterization of Gold Nanoparticles by Isolated Bacterial from Kerman Sarcheshmeh Copper Mine Soil and the study of their cytotoxic properties
Nano-Biotech MedicalThe present study was designed to isolate bacterial strain capable of gold nanoparticles (Au NPs) production followed by...Read more
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Comparative miR34a expression profile analysis in tumor and normal tissues of patients with colorectal cancer
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer is a type of prevalent cancers in populations and allocates numbers of mortality. Recently, researcher...Read more
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rDKK1 production and purification as an antigen
Cancer; Prevention, Diagnosis and TreatmentA critical goal in prevention and control of cancer is early detection of cancer. It is suggested that the Dickkopf1 (DK...Read more
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Shedding light on new form of combination therapy in acute promyelocyte leukemia
Cancer; Prevention, Diagnosis and TreatmentAlthough physicians have taken a variety approaches for the treatment of acute promyelocytic leukemia (APL), there is no...Read more
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The latest developments in pharmaceutical biotechnology
Nano-Biotech MedicalBackground and Aim: Biotechnology has produced over 200 types of drugs and new vaccines that include products for the tr...Read more
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CRISPR/Cas9-mediated designing of lung adenocarcinoma mouse model by method of knock-in
Medical GeneticsMolecular genetic studies in cell and animal models have evolved our knowledge of discovering causal mechanisms relating...Read more
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Progress and Prospect of Nanotechnology in Stem Cells
Nano-Biotech MedicalThe apparition of nanotechnology has paved the way for an obvious understanding of stem cell therapy in vivo and by repe...Read more
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Identifying MicroRNA-mRNA regulatory network in breast cancer sample with drug resistance
Cancer; Prevention, Diagnosis and TreatmentA computational approach to prediction of miRNA targets narrowing down potential target sites for experimental validatio...Read more
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A Turn-Off Fluorescent Sensor Based On Carbon Dots for Sensitive Detection of Tetracycline in Milk
Nutrition and HealthThe detection of tetracycline in animal-derived food and drug is very significant, because of its harmful effects on hum...Read more
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Production of protein A containing Thiol Group for binding to fluorescence dye To increase the sensitivity of antibody detection
Nano-Biotech Medicalstaphylococcal Protein A is a cell wall component which has the ability to bind to immunoglobulins of different animal s...Read more
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The Study of the Requested Antibiotics during Each Patient’s confining to Bed in Namazi 1000 beds hospital, May 22nd to July 21st
Microbiology and Infectious DiseasesOccurring resistive microbial trends is one of basic obstacles in infection disease treatments. Prescribing too much ant...Read more
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Anti-clostridial role of probiotics in prevention and treatment of Clostridium difficile infections
Microbiology and Infectious DiseasesPatients with varied conditions, such as Antibacterial therapy, Cancer chemotherapy, and gastrointestinal surgery are at...Read more
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Characterization of a produced monoclonal antibody against testis antigens on the mouse embryogenesis
Medical GeneticsThe complex series of cellular signaling molecules and transcriptional factors are involved in differentiation and devel...Read more
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Effect of Extract of Origanum Vulgare on the activity of alanine aminotransferase enzyme in healthy and diabetic mice
Metabolism and Metabolic DiseasesWild Thyme is a great medicinal plant that grows in different areas of the Mediterranean and some parts of Asia.Present ...Read more
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Evaluation of TCA cycle in patients with acute myeloid leukemia
Cancer; Prevention, Diagnosis and TreatmentAcute myeloid leukemia (AML) is the most type of acute leukemia in adults. In solid tumors, alteration of energy metabol...Read more
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The Relationship Between Renin- Angiotensin System Genetic Variation and Autism in Iranian Children; A Case –Control Study
Medical GeneticsAutism is a disease of complex nature with a significant genetic component.The importance of Renin-Angiotensin System(RA...Read more
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Serum level of Dipeptidyl peptidase-4 as a potential biomarker for medullary thyroid cancer
Cancer; Prevention, Diagnosis and TreatmentAdipokines are the proteins secreted from adipose tissue which play an important role in the control of metabolism. Dipe...Read more
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Evaluation of circulating prognostic tumor marker DNA in the blood of brain tumor patients
Cancer; Prevention, Diagnosis and TreatmentRecent evidence suggests that tumor cells may release DNA into the circulation, which is enriched in the serum and plasm...Read more
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Identifying Linking Mechanisms of Allergy and Cancer
Cancer; Prevention, Diagnosis and TreatmentAllergy and cancer are prevalent diseases and cause a lot of morbidity and mortality. In recent years, many studies have...Read more
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SNP genotyping within INS, INSR, TCF7L2 and PPR- y genes associated with type 2 diabetes in India
Medical GeneticsA pilot population-based study was carried out to evaluate linkage between singlenucleotide polymorphisms within the kn...Read more
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Investigating th expression of E-cadherin gen among patients suffering from stomach cancer in West Azerbaijan province
Medical GeneticsGastritis Cancer is one of the general death causes of cancer all over the world. According to the results of the resea...Read more
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Sensitivity of levofloxacin in combination with ampicillin-sulbactam and tigecycline against multidrug-resistant Acinetobacter baumannii
Microbiology and Infectious DiseasesDuring the last decades, emergence of antibiotic resistance among A. baumannii has been considered as a worldwide alarm....Read more
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Comparison of chondrocyte cells survival in alginate and throat fibrin scaffolds using MTT assay for repair and treatment of cartilage
Stem cell and Medical ApplicationsArthritis or osteoarthritis is the most common disease that is counted as the category of arthritis in which the joint c...Read more
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Gankyrin expression in ovarian cancer and its correlation with clinicopathological parameters
Cancer; Prevention, Diagnosis and TreatmentGankyrin (p28GANK) is a novel oncoprotein which regulates the phosphorylation of retinoblastoma protein (pRb) and degrad...Read more
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the effect of Lactobacillus acidophilus (La) and Lactobacillus rhamnosus (Lr) on proliferation and invasion of Colorectal cancer cells (Caco2).
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer is one of the most common epithelial cancers in the world. Many studies have been conducted on the inh...Read more
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Evaluation of gonadotropin hormones in non-obstructive azoospermia patients
Women and Reproductive HealthInfertility refers to the inability of couples to achieve a successful pregnancy after a year of sexual intercourse with...Read more
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Triplet repeats in Androgen receptor and it's relation with cardiovascular disease
Medical GeneticsCardiovascular disease is one of the main cause of death in all around the world and researches indicated that in United...Read more
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The effect of ziziphora extract on the expression of the Claudin_1 gene in the AGS cell line
Cancer; Prevention, Diagnosis and TreatmentClaudins are the main structural and functional proteins of tight junctions in epithelial cells. The altered expression ...Read more
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Comparative study of Calendula officinalis and Matricaria chamomilla extracts on Cisplatin induced neuropathic pain
Cancer; Prevention, Diagnosis and TreatmentCisplatin is one the most important cancer chemotherapy agents that uses for two decades. Neuropathic pain induced by th...Read more
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Review: ASD heritability
Medical GeneticsAutism Spectrum Disorder (ASD) is one of the most common neurodevelopmental disorders; due to its high occurrence rate a...Read more
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Optical, structural and antibacterial properties assessment of ZnO:Mn nanoparticles
Nano-Biotech Medicalwith the rapid development of human life, controlling the harmful impacts of microorganisms is essential. The current st...Read more
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An Evaluation of Tissue Destruction Time in Phrenic Nerve after Death and Counting the Number of Nerve Fibers in C3, C4 and C5 Branches
Cancer; Prevention, Diagnosis and Treatmentمقدمه اعصاب فرنیک چپ و راست، محرک اصلی عضلة دیافراگم میباشند( .)5ای...Read more
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Crocin suppresses multidrug resistance in MRP overexpressing ovarian cancer cell line
Cancer; Prevention, Diagnosis and TreatmentCrocin, one of the main constituents of saffron extract, has numerous biological effects such as anti-cancer effects. M...Read more
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Evaluation of Adiponectin Hormone in Diabetic and Non-diabetic Patients
Metabolism and Metabolic DiseasesAdipose tissue is currently considered as a hormonally active system in the control of metabolism and not only as a stor...Read more
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Identification of bacterial agents of urinary tract infection in patients referred to a laboratory during six months
Microbiology and Infectious DiseasesEstablishing a diagnosis of symptomatic UTI requires a patient to have symptoms and signs of a UTI and laboratory tests ...Read more
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Detection of Mycoplasma arginini contamination in biological products by PCR
Microbiology and Infectious DiseasesIntroduction: Mycoplasmas are one of the most important pollutants in biological products and cell cultures, and are a...Read more
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Targeted killer gene therapy of breast cancer cells using Pseudomonas exotoxin A
Cancer; Prevention, Diagnosis and TreatmentTargeted expression of killer genes in tumor cells ensures specific elimination of cancer cells with minimal effect on n...Read more
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Kidney Cancer, Cancer without Early Symptoms
Cancer; Prevention, Diagnosis and TreatmentThe kidneys are a pair of organs in the human body that are located on either side of the spine and in the lower abdomen...Read more
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Protective effect of silymarin on plasma membrane and DNA integrity of human sperm treated with cadmium chloride
Women and Reproductive HealthCadmium, as an environmental pollutant, exerts its destructive effects on male reproductive system and sperm by inducing...Read more
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Selection of Peptides Specific to PDL-1 Using Phage Display Technology
Cancer; Prevention, Diagnosis and TreatmentPDL-1 is a well-known antigen to target tumor specifically. It can interact with PD-1 receptor on tumor infiltrating T-l...Read more
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Antimicrobial effects of new designed 2-amino-tetrahydro-4H-chromene-3-carbonithril derivatives against some pathogenic microbial strains
Microbiology and Infectious DiseasesChromenes are natural compounds which also called benzopyrane derivatives and chromene-4-one and had several biological ...Read more
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Silencing of TIM-3 expression by miR-326 affects apoptosis and proliferation of human HL-60 leukemia cell line
Cancer; Prevention, Diagnosis and TreatmentLeukemia Stem Cells (LSCs) are the main reason for drug-resistance and disease relapse in Acute Myeloid Leukemia (AML). ...Read more
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Rosmarinic acid, a Anti-glycation agent, inhibits protein glycation in vitro
Metabolism and Metabolic DiseasesDiabetes mellitus is one of the most non-communicable diseases and is the fifth leading causes of death in most of the d...Read more
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Interaction of Methotrexate on Stability and structure of Human Serum Albumin
Nano-Biotech MedicalHuman serum albumin(HSA) as the most abundant carrier protein in blood plasma has been widely studied. HSA is often used...Read more
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Inflammatory markers, vitamin D status and FokI polymorphism of the VDR gene in overweight women
Nutrition and HealthThe present study aimed to evaluate the relationship between inflammatory markers, vitamin D status and FokI polymorphis...Read more
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The effects of minoxidil on gene expression in the bulb and bulge region of hair follicles by Real time-PCR
BeautyMinoxidil is the most common drug used for treatment androgenic alopecia.Studies have shown that this drug can increase ...Read more
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Pattern of efflux pump genes in imipenem resistant Acinetobacter isolates
Microbiology and Infectious DiseasesAcinetobacter species are opportunistic pathogens and responsible for various types of nosocomial infections. They are i...Read more
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Effect of hydroalcoholic leaf extract of Ziziphora tenuior L. on pain in male rats
Microbiology and Infectious DiseasesZiziphora tenuior is one of the traditional medicinal herbs; the main active chemical composition of this herb is an ing...Read more
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Survey of various aspects in polycystic ovary syndrome (PCOS)- A review
Women and Reproductive HealthPolycystic ovary syndrome (PCOS) is a complex endocrine disorder affecting 5–10% of women of reproductive age. It has ...Read more
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Survaey polymorphism rs 866751883 ADAM2 gene infertile men referred to infertility treatment centers in East Azerbaijan which under treatment with IUI (Intrauterine Insemination)
Medical GeneticsOne of the most important genes in human infertility is ADAM2 gene. The gene function is the important in the process of...Read more
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Microfluidic Nanocomplex-Based Localized Gene Delivery Platform for Bone Tissue Engineering.
Stem cell and Medical ApplicationsAnnually more than 2.2million bone graft procedures take place in worldwide. Biomaterials-based bone tissue engineering ...Read more
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Silencing of Mcl-1 and Bcl-2 by miR-15 Induces Apoptosis and Increases the Chemosensitivity of the CLL Cells
Cancer; Prevention, Diagnosis and TreatmentDespite advances in cancer therapy, drug resistance is a major problem in leukemia. Overexpression of anti-apoptotic pro...Read more
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Induction of apoptosis by silibinin in SKBR3 breast cancer cell line through activation of caspase 3/7
Cancer; Prevention, Diagnosis and TreatmentThe poor prognosis of breast cancer is due to its resistance to the conventional treatments. Therefore, researchers are ...Read more
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Nephroprotective effect of Lavandula officinalis L. ethanolic extract in alloxan induced diabetic rats
Nutrition and HealthDiabetes mellitus (DM), a metabolic disorder is a major public health problem in both developed and developing countries...Read more
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study of microbial quality of some food samples
Nutrition and Healthbacterias are considered as the most important factor to cause infection and food poisoning ,so that microbial contamina...Read more
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Investigation of CYP21A2 gene variants in Iranian patients with congenital adrenal hyperplasia
Medical GeneticsCongenital adrenal hyperplasia (CAH) is an autosomal recessive disease characterized by impaired adrenal steroidogenesis...Read more
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Detection of Hepcidin biomarker in plasma of patients with stomach tumor before and after treatment
Cancer; Prevention, Diagnosis and Treatment: cancer is a very important public health problem, which is the main cause of death inindustrialized countries and incr...Read more
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Investigating the role of exon7 axin2 in colorectal cancer (Laboratory and bioinformatics studies)
Cancer; Prevention, Diagnosis and TreatmentIn Iran, colon cancer is the third most common cancer. WNT pathway changes are commonly reported in this cancer. Among t...Read more
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Study of HER2 gene expression in AGS cell line after treatment of cells with Crocus sativus (Iranian Saffron) extract
Cancer; Prevention, Diagnosis and TreatmentThe study of HER-2 gene in cancers, especially gastric cancer, is of great importance. This gene, has been shown to inc...Read more
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Assessment of energy and water-soluble vitamins intake in the elderly under health care, Isfahan, Iran
Nutrition and HealthThe B vitamins are essential nutrients to maintain nutritionally healthy body. These water soluble vitamins are critical...Read more
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Dietary intake of antioxidants in elderly: A case-control study in Iran
Nutrition and HealthNutrient deficiencies such as antioxidants are common problems in elderly subjects which can result in different cancers...Read more
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The role of natural antioxidants in treatment of cancer
Cancer; Prevention, Diagnosis and TreatmentCancer is one of the most common causes of death in advanced industrial societies. With the prevalence and spread of can...Read more
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Biological and Molecular Diversity in Telomerase: Characteristics of hTERT in Human, Vertebrates and Yeast
Medical GeneticshTERT (human telomerase reverse transcriptase) is the catalytic subunit of telomerase enzyme, and is essential for its ...Read more
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Molecular identification of Aspergillus isolated from livestock feed and poultry using ASAP1 sequencing
Microbiology and Infectious DiseasesThe contamination of livestock feed and poultry with toxic fungi, such as aspergillus in the air and the environment, is...Read more
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analysis of circulating mir-141, and mir-375 in small cell lung cancer patients
Medical Geneticslung cancer is the main cause of mortality from cancer in the world. small cell lung cancer is the most invasive lung ca...Read more
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Genotyping of Escherichia coli strains isolated from hospitals sewage
Microbiology and Infectious DiseasesToday one of the most common problems in the health society is the way of treating multidrug resistant (MDR) organisms. ...Read more
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Biosynthesis of Tellurium nanoparticles by Streptomyces isolate B2.1369F
Nano-Biotech MedicalBiosynthesis of Tellurium nano particles (TNPs) has great advantage since it has no chemical contamination in the enviro...Read more