: pesticides and pesticides are harmful to the human health and increase the level of inflammatory factors and cause inflammation occurrence. the most important indices of inflammation are tumor necrosis factor alpha (tnf-α) and c - reactive protein (hs-crp). therefore, this study evaluated the effect of pesticide spraying activity on hs-crp and tnf- levels in spraying workers.
Methods
This practical study was conducted to evaluate the serum level of and tnf-α and hs-crp among sprayer workers in east azarbaijan. target population was 90 people and was divided into two treatment groups (45 man) with six-month spraying experience and the control group (45 man) without any spraying experience. blood samples were enrolled from all subjects and after serum preparation, levels of hs-crp were measured using immunoturbidimetry method and tnf-α levels by elisa method and orgenium kits (finland). the results were compared using spss version 19 and independent sample t-test method(p<0.05).
Results
: the mean serum levels of hs-crp and tnf-α in the case group showed a non-significant change compared to the control group.
Conclusion
The results of this study showed that toxins and spraying activity didnot change in the level of serum hs-crp and tnf- in sprayer workers.
