Majid Mahdavi
University of TabrizTabriz, Iran
Abstracts, [Author]
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The Relationship between STR-PCR Chimerism Analysis and Chronic GvHD Following Hematopoietic Stem Cell Transplantation
Cancer; Prevention, Diagnosis and TreatmentGraft-versus-host disease (GvHD) is one of the serious complications of HSCT. Its prevalence has been reported as 20-50 ...Read more
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The effect of 5μM benzoquinone on CXCL12 and KITLG genes in mesenchymal stem cells found in bone marrow niche
Stem cell and Medical ApplicationsChronic exposure to benzene is known to damage the BM resulting in development of different types of leukemia. Extrinsi...Read more
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In silico analysis of Siglec14 as a target for hsa-let-7e-5p
Medical GeneticsSialic acid-binding immunoglobulin-type lectins (Siglecs) are transmembrane proteins that are expressed on the cell surf...Read more
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conjugation DNA aptamer HER-2 and anti mir-21 as a pharmaceutical agent targeted for apoptosis in MCF7cancer cell line
Cancer; Prevention, Diagnosis and TreatmentIn the past decade, it has become apparent that certain small RNA plays an important role in the initiation, progression...Read more
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Analysis of hypermethylation of NFK-B ،TRAF1 and TRAF2 genes in patients with oral squamous cell carcinoma
Medical GeneticsCancer is a fatal disease caused mainly by environmental factors that mutate genes encoding critical cell-regulatory pr...Read more
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Evaluation of NTT and Double-Test in screening of Down Syndrome
Women and Reproductive HealthPrenatal diagnosis of genetic, congenital and hereditary diseases is the first step to prevent and control these prob...Read more
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Prognostic significance of c-Myc gene amplification and protein expression in brain tumors: Astrocytoma and meningioma
Cancer; Prevention, Diagnosis and TreatmentAstrocytoma and meningioma are the most common primary brain tumors. c-Myc as a member of MYC proto-oncogenes has recent...Read more
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Investigation of deaths caused by cancer in Bandar Anzali in 2014
Cancer; Prevention, Diagnosis and TreatmentCancer is one of the main causes of death and disability in Iran and the world. This study was conducted to evaluate the...Read more
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Evaluation and comparison of digestion in two traditional and contemporary medicine schools And its effect on the treatment of diseases
Nutrition and HealthIn traditional medicine, one of the three most important nutritional principles is digestion. In our digestion, we deal ...Read more
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Improvement of Prognostic model for breast cancer recurrence by data mining methods
Cancer; Prevention, Diagnosis and TreatmentIn Iran, every year 10,000 people suffer from breast cancer, of which half of them are under the age of 50. The recurren...Read more
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Anti-inflammatory activity of Caspian Cobra (Naja naja oxiana) snake Venom in EAE model of MS
Medical GeneticsMultiple sclerosis (MS) is a chronic neuroinflammatory demyelinating disorder of the Central Nervous System (CNS) with a...Read more
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studying the effect of silibinin in some of hippo signaling pathway genes , in T47D and MCF7 Breast cancer cell lines with 3D culture.
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is one of the most common malignancy diseases world and is the second leading cause of cancer in women. S...Read more
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Evaluating the genetic variations in functional domains coding regions of MSMB in infertile men with unexplained infertility
Medical GeneticsΒ-Microseminoprotein(MSMB) is one of the most abundant proteins in human seminal plasma. This protein binds to head and...Read more
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study of mesenchymal stem cell differentiation to chondrocyte on electrospun nanofibrous polyvinyl alcohol alginate sulfat blend
Stem cell and Medical ApplicationsCartilage tissue engineering is used as a potential solution for replacing or repairing damaged tissue. In this method, ...Read more
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The effects of specific expression of Apoptin under control of PSES and PSA promoter on apoptosis of LNCaP cells
Cancer; Prevention, Diagnosis and TreatmentApoptotic effects of viral protein Apoptin has been demonstrated in numerous studies. However, its tumor specificity has...Read more
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Comparison of in vitro survival of mononuclear cells derived from B-CLL patients with or without BAFF & APRILL cytokines
Cancer; Prevention, Diagnosis and TreatmentThis article studies the antiapototic effect of cytokines BAFF & APRIL on the survival of mononuclear cells derived ...Read more
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Evaluation of cardiac differentiation potential of menstrual blood- derived stem cells seeded in biocompatible Bombyx mori silk fibroin scaffold in co-culturing with neonatal rat Cardiomyocytes
Stem cell and Medical ApplicationsCardiovascular disorders are leading cause of million deaths each year which reveals the significance of current limitat...Read more
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Serum level of Dipeptidyl peptidase-4 as a potential biomarker for medullary thyroid cancer
Cancer; Prevention, Diagnosis and TreatmentAdipokines are the proteins secreted from adipose tissue which play an important role in the control of metabolism. Dipe...Read more
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Pattern of efflux pump genes in imipenem resistant Acinetobacter isolates
Microbiology and Infectious DiseasesAcinetobacter species are opportunistic pathogens and responsible for various types of nosocomial infections. They are i...Read more
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Function of Diabetes Mellitus on the Body, Diagnosis until Treatment
Medical GeneticsDiabetes mellitus is a metabolic pathway in which the insulin hormone is secreted or incompletely secreted; it is a meta...Read more
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Additive Cytotoxic Effect of Apoptin and Chemotherapeutic Agent Docetaxel on LNCaP Cell Lines
Cancer; Prevention, Diagnosis and TreatmentUnfortunately although chemotherapy is primary therapy for most types of advanced prostate cancer, conventional chemothe...Read more
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Designing and cloning and expression of bean defensin in human embryonic kidney cells and evaluating their antibacterial function
Microbiology and Infectious DiseasesDefensins are among the most important cationic peptides that their presence in a wide range of herbs and animals has be...Read more
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Molecular detection of factor 5 Leiden (G1691A) and its relation with TNF- α gene polymorphism in human abortion
Medical GeneticsAbortion is the most common of pregnancy complications. In the pathogenesis of abortion as a multifactorial disease, gen...Read more
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Naltrexone changes the expression of lipid metabolism-relatedproteins in the endoplasmic reticulum stress induced hepatic steatosis in mice
Metabolism and Metabolic DiseasesEndoplasmic reticulum (ER) stress is closely associated with several chronic diseases such as obesity, atherosclerosis, ...Read more
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Study of MiRNA-873 expression in Ectopic pregnancy, Endometriosis and Ovarian cancer (review)
Medical GeneticsMicroRNAs are small non-coding RNA molecules that have functions in post-transcriptional regulation of gene expression. ...Read more
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Biological and Molecular Diversity in Telomerase: Characteristics of hTERT in Human, Vertebrates and Yeast
Medical GeneticshTERT (human telomerase reverse transcriptase) is the catalytic subunit of telomerase enzyme, and is essential for its ...Read more
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rDKK1 production and purification as an antigen
Cancer; Prevention, Diagnosis and TreatmentA critical goal in prevention and control of cancer is early detection of cancer. It is suggested that the Dickkopf1 (DK...Read more
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Cloning of Human THAP11 Gene in Lentiviral Vector
Stem cell and Medical ApplicationsThap11, the most recent described member of THAP domain family, which is in volved in cell proliferation and described a...Read more
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Comparison of antimicrobial activity of hydroalcoholic extract of fig(Ficus carica) against Staphylococcus aureus(MSSA & MRSA) with some antibacterial drugs
Microbiology and Infectious DiseasesStaphylococcus aureus is one of the five most common causes of hospital infections and death the worldwide. The excessiv...Read more
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Relationship between Hypertension in the First Trimester of Pregnancy with Weight and Height at Birth
Women and Reproductive HealthBackground: Hypertensive disorders with a prevalence of %5-10 are among the main causes of morbidity and mortality in mo...Read more
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TP53 hotspot mutations and expression of c-Myc oncogenes in astrocytoma and meningioma
Medical GeneticsMost studies have shown that there are association between the development and malignancy of brain tumors and tumor supp...Read more
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Purification of poly ribosylribotil phosphate capsule from Heamophilus influenza type- b strain ATF2 cultivated in bioreactor
Microbiology and Infectious DiseasesHaemophilus influenzae is a small gram negative cocobacilli non motile and can be seen as pleomorphic. H.inf.can cause ...Read more
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The Study of the Requested Antibiotics during Each Patient’s confining to Bed in Namazi 1000 beds hospital, May 22nd to July 21st
Microbiology and Infectious DiseasesOccurring resistive microbial trends is one of basic obstacles in infection disease treatments. Prescribing too much ant...Read more
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Lack of association between Hypoxia Inducible Factor rs11549465 polymorphism and Preeclampsia
Medical GeneticsPre-eclampsia (PE) is an obstetric disorder that may result inmaternal and neonatal mortality and morbidity. Placental h...Read more
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Anti-Diabetic Effects of Methanolic Extract of Calendula officinalis through Increased Antioxidant Enzymes Activity
Metabolism and Metabolic DiseasesDiabetes is a big challenge in the health care system. ROS generation is the major mechanisms which is involved in the p...Read more
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Ischemia-modified albumin as an oxidative stress biomarker in acute coronary syndrome
Metabolism and Metabolic DiseasesFree radicals increasing or Antioxidants decreasing may contribute to impair the equilibrium between oxidant and antioxi...Read more
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The Possible Role of B. thetaiotaomicron-derived Outer Membrane Vesicles (OMVs) in the Modulation of Cholesterol Uptake and Diet-induced Obesity
Metabolism and Metabolic DiseasesAltered gut microbiota composition has been proven to be associated with several disorders including metabolic syndrome....Read more
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The effect of vinorelbine on HMG proteins in lung cancer A549 cells
Cancer; Prevention, Diagnosis and TreatmentVinorelbine is a semisynthetic vinca alkaloid antitumor drug, widely used in the treatment of cancers such as advanced n...Read more
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Survey of various aspects in polycystic ovary syndrome (PCOS)- A review
Women and Reproductive HealthPolycystic ovary syndrome (PCOS) is a complex endocrine disorder affecting 5–10% of women of reproductive age. It has ...Read more
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A genetic variant in CDKN2A/2B locus was associated with poor prognosis in patients with esophageal squamous cell carcinoma
Cancer; Prevention, Diagnosis and TreatmentEsophageal squamous cell carcinoma (ESCC) is among the leading causes of cancer related death. Despite extensive efforts...Read more
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Investigation of Interleukin-17 gene polymorphism in patients with gasteric carcinoma and comparsion with healthy individuals reffered parison to the healthy control in Golestan Province 's hospitals.
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is one of the most common types of human cancers globally, which remains an important public health burde...Read more
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personalized medicine in oncology
Medical GeneticsThe term peronalized medicine is used for the identification of optimal drug type and optimal drug dosage for individual...Read more
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Characterization of a produced monoclonal antibody against testis antigens on the mouse embryogenesis
Medical GeneticsThe complex series of cellular signaling molecules and transcriptional factors are involved in differentiation and devel...Read more
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Astaxanthin decreases cell viability in MDA-MB-231, but not in non-tumorigenic human breast cell line MCF 10A
Cancer; Prevention, Diagnosis and TreatmentConsidering the high prevalence of breast cancer in Iran, its rising incidence, and the high mortality rate of patients ...Read more
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Reproductive Health Training Program on Students in IRAN: An Action Research Approach
Women and Reproductive HealthTransition from adolescence to adulthood is one of the important periods in the individual life. New behaviors are learn...Read more
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Green synthesis of Silver nanoparticles by Alhagi camelorum gum
Nano-Biotech MedicalSilver nano particles (AgNPs) are used in textiles, cosmetics, tooth brushes, home appliances, food packages and many ot...Read more
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Design, synthesis and application of conjugated gold nanoparticles in photodynamic therapy
Nano-Biotech MedicalPhotodynamic therapy (PDT) has been developed as a novel method for cancer therapy. PDT involves the combined use of a p...Read more
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Inhibition of cell growth in HCT-116 human colorectal cancer cell line by sodium butyrate, a HDAC inhibitor
Cancer; Prevention, Diagnosis and TreatmentSodium butyrate (NaBu), a histone deacetylase (HDAC) inhibitor, is the byproduct of anaerobic microbial fermentation ins...Read more
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Correlation between oral health status and salivary total antioxidant capacity in type 2 diabetes mellitus among Iranian adults
Metabolism and Metabolic DiseasesDiabetes mellitus is a chronic metabolic disease leading to several complications. Among these, dental caries are consid...Read more
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Investigation of prevalence class 1 and 2 integron gen in Escherichia coli from Isolated clinical samples Tehran’s hospitals
Microbiology and Infectious DiseasesAs the antibiotics are misused, Integrons are the moving genetic factors which carry resistance gens and have an import...Read more
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Cancer Stem Cell Therapy Based on Nanostructure Drug Vehicle, PMBN-IL3-GA
Nano-Biotech MedicalTo overcome difficulty of cancer treatment by conventional chemotherapy methods, the targeting drug delivery based on Na...Read more
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Effect of Extract of Origanum Vulgare on the activity of alanine aminotransferase enzyme in healthy and diabetic mice
Metabolism and Metabolic DiseasesWild Thyme is a great medicinal plant that grows in different areas of the Mediterranean and some parts of Asia.Present ...Read more
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Determination of GPR55 overexpression by quantitative real-time PCR as a biomarker for skin SCC detection
Cancer; Prevention, Diagnosis and TreatmentChronic wounds resemble the wounds arising with skin squamous cell carcinoma (SCC). Since they are cancerous, they shoul...Read more
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A novel technique to estimate sex ratio in semen
Women and Reproductive HealthOffspring sex is one of the most important factors in controls sex-linked genetically transferred diseases and also for ...Read more
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study of promoter methylation status of pax5 gene in patients with gastric cancer
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is the fifth leading cause of cancer and is also the third leading cause of death in the world .Although ...Read more
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Study genetic susceptibility polymorphisms for chronic lymphocytic leukemia in Iranian population.
Medical GeneticsChronic lymphoid leukemia (CLL) is the most common form of leukemia found in adults. CLL is a monoclonal disorder that w...Read more
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Preparation and assessment of chitosan-polyethylenimine-carboxymethyl dextran nanoparticles for efficient siRNA delivery in vitro
Nano-Biotech MedicalAmong polycation nanoparticles, chitosan nanoparticles (Ch) have emerged as promising carriers for gene delivery, nevert...Read more
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Detecting of herpes simplex virus’s DNA in the breast tumor, using polymerase chain reaction technique
Medical GeneticsIt has been proven that cancer cells formation can be due to the herpes simplex virus infection in human beings. The ai...Read more
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Review: ASD heritability
Medical GeneticsAutism Spectrum Disorder (ASD) is one of the most common neurodevelopmental disorders; due to its high occurrence rate a...Read more
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Study of PAX5 gene expression in patients with gastric cancer
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is one of the biggest health problems in the world. Due to the lack of many carcinogenic biomarkers and t...Read more
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Anti-cancer effect of redroot pigweed as weed plant species
Cancer; Prevention, Diagnosis and TreatmentLeukemia cancer is currently one of the major causes of cancer-related deaths among humans. Extracts of plants including...Read more
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Some candidate Biomaterials for Amniotic Membranes (AM) Regeneration: a review
Stem cell and Medical ApplicationsAmniotic Membranes (AM) wich form the amniotic sac filled by amniotic fluid and completely surrounds the embryo/fetus. I...Read more
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Thiolated chitosans development and in vitro evaluation of apermeation enhancing oral drug delivery system
Nano-Biotech MedicalThis study investigated the in vitro release of Vancomycin and Amphotericin B fromnovel mocuadhesive chitosan nanofibers...Read more
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Can air pollution impact of sperm parameters? A meta- analysis
Women and Reproductive HealthAir pollution is common in all countries and affects reproductive functions in men and women. It particularly impacts sp...Read more
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Survey of Changes gene expression levels of SAP 1-3 Candida albicans samples treated with treated with Fluconazole-loaded PLGA Nanospheres, in comparsion with drug Fluconazole
Microbiology and Infectious DiseasesSecreted Aspartyl Proteinase (SAP) is one of the main virulent factors in the pathogenesis of Candida. This enzyme is en...Read more
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Comparison of chondrocyte cells survival in alginate and throat fibrin scaffolds using MTT assay for repair and treatment of cartilage
Stem cell and Medical ApplicationsArthritis or osteoarthritis is the most common disease that is counted as the category of arthritis in which the joint c...Read more
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Promoter Hypermethylation Analysis of the Tumor Suppressor Gene RASSF1A in Iranian Endometrial Carcinoma Patients
Cancer; Prevention, Diagnosis and TreatmentEndometrial cancer is the most common malignancy among women in developed countries. More endometrial cancers occurs in ...Read more
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Investigating the specificity of the specific lytic bacteriophage against Salmonella bacteria and its effect on the hep2 cell line
Microbiology and Infectious DiseasesResistance to antibiotic treatments is one of the increasing problems. Therefore, alternative methods to reduce antibiot...Read more
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Evaluation of the effects of fish oil-derived Eicosapentaenoic acid on the proliferation of colorectal cancer cell line (hct116)
Cancer; Prevention, Diagnosis and Treatmentof these studies have indicated that Eicosapentaenoic acid (EPA) can induce apoptosis and reduce proliferation in cancer...Read more
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Determination Of intestinal Escherichia coli Pathotypes Frequency in Tehran Province By PCR
Microbiology and Infectious DiseasesEscherichia coli (E.coli) is an important member of the normal intestinal microflora for mammals, including humans.Diarr...Read more
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Managing The Abnormal Papsmear In Pregnancy
Cancer; Prevention, Diagnosis and TreatmentCervical cancer is the most common malignancy diagnosed during pregnancy . The incidence of abnormal pap smear in pregna...Read more
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CRISPR/Cas9-mediated designing of lung adenocarcinoma mouse model by method of knock-in
Medical GeneticsMolecular genetic studies in cell and animal models have evolved our knowledge of discovering causal mechanisms relating...Read more
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Blocking of vascular endothelial growth factor signaling through design of bi-specific single domain antibody
Nano-Biotech MedicalOver-expression of vascular endothelial growth factor (VEGF) leads to the proliferation and neovasculature of cancer cel...Read more
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Overexpression of cancer stem cell protein, Piwil2, promotes the expression of anti-apoptotic and proliferative genes in the gastric cancer cell line MKN-45
Cancer; Prevention, Diagnosis and TreatmentPiwi-like RNA-mediated gene silencing 2 (Piwil2) is an oncogene that is highly expressed in different tumors including ...Read more
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A Review Article on Treatment with Stem Cells: Complications and Problems
Stem cell and Medical ApplicationsNowadays, various methods of treatment with stem cells are developing fast while such treatments have different and some...Read more
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Snake venom: an anticancer agent in immunotoxin therapy
Cancer; Prevention, Diagnosis and TreatmentCancer is the second leading cause of death worldwide. Therefore, many studies are underway to innovate more efficient t...Read more
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Selection of Peptides Specific to PDL-1 Using Phage Display Technology
Cancer; Prevention, Diagnosis and TreatmentPDL-1 is a well-known antigen to target tumor specifically. It can interact with PD-1 receptor on tumor infiltrating T-l...Read more
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Association between the CYP2E1 polymorphisms and CML risk in Iranian population
Medical GeneticsPolymorphism in the genes encoding detoxification enzymes results in variability to metabolize carcinogens and cause int...Read more
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Investigating the effects of saffron and melatonin with radiotherapy on viability of Hela cells
Cancer; Prevention, Diagnosis and TreatmentCancer is one of the biggest threats to human life. None of cancer treatment have not succeeded completely. One of the n...Read more
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Cloning and expressing the chimeric peptide lactoferricin-lactoferampin camel in Lactococcus lactis for promising as a candidate for oral medication
Nutrition and HealthLactococcus lactis is known as probiotics due to its lack of harmful toxins. Because of its high growth potential and re...Read more
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Anticonvulsant, neuroprotective and behavioral effects of magnesium sulfate on pentylenetetrazol-induced seizures in male Wistar rats
Nutrition and HealthMagnesium (Mg2+) is the second most abundant divalent and ubiquitous intracellular cation in mammalian cells and an ess...Read more
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Genetic variations of Cholesteryl ester transfer protein and diet interactions in relation to lipid profiles and coronary heart disease: A systematic review
Nutrition and HealthThe number of investigations on diet–genotype interactions in the prevention or treatment of dyslipidemia have increas...Read more
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Evaluation of nitrosative stress in sprayer workers
Metabolism and Metabolic DiseasesAgricultural pesticides have an important impact on human health and farmers are people who are more exposed to pesticid...Read more
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Microfluidic Nanocomplex-Based Localized Gene Delivery Platform for Bone Tissue Engineering.
Stem cell and Medical ApplicationsAnnually more than 2.2million bone graft procedures take place in worldwide. Biomaterials-based bone tissue engineering ...Read more
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The effects of minoxidil on gene expression in the bulb and bulge region of hair follicles by Real time-PCR
BeautyMinoxidil is the most common drug used for treatment androgenic alopecia.Studies have shown that this drug can increase ...Read more
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Detection of Mycoplasma arginini contamination in biological products by PCR
Microbiology and Infectious DiseasesIntroduction: Mycoplasmas are one of the most important pollutants in biological products and cell cultures, and are a...Read more
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Molecular Cloning of Clostridium perfringens Type D & Clostridium septicum vaccine strain epsilon alpha fusion gene in E. coli
Medical GeneticsDesigning and producing a proper fusion construction is the most important problem of producing large quantities of fu...Read more
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Optimization of epi-drug combination against Glioblastoma multiform cell line (U251) using Response Surface Methodology
Cancer; Prevention, Diagnosis and TreatmentGlioblastoma multiform (GBM) is the most common and aggressive form of primary brain cancer and has a dismal prognosis, ...Read more
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Motor neuron differentiation potential of human umbilical cord blood- derived mesenchymal stem cells, in vitro
Stem cell and Medical ApplicationsMany people suffer from spinal cord injuries annually. These deficits usually threaten the quality of life of patients. ...Read more
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Preparation and optimization of chitosan nanoparticles containing vancomycin
Nano-Biotech MedicalRecently, some novel drug delivery systems were designed to control drug release. The using of polymeric nanoparticles a...Read more
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Evaluation and study of antimicrobial activity of nanoliposomal meropenem against Pseudomonas aeruginosa isolates
Nano-Biotech MedicalThe aim of this study was to evaluate the antimicrobial efficacy of liposomal meropenem formulation against clinical and...Read more
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Skin anti-ageing potential of Lactobacilli exopolysaccharides (EPSs) on human fibroblast
BeautySkin aging is a complex biological process influenced by a combination of endogenous or intrinsic and exogenous or extri...Read more
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Molecular monitoring of Chronic Myeloid Leukemia in Chronic Phase (CML-CP)
Medical GeneticsQuantification of the BCR-ABL transcript is recommended to follow-up CML patients that treated by Imatinib mesylate (IM)...Read more
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Development of an Antagonistic TGF-β by Directed Blocking of its TβRI Binding Site to Inhibition TGF-β Signaling
Cancer; Prevention, Diagnosis and TreatmentTransforming growth factors beta (TGF-βs) play vital roles in regulating cell growth, differentiation and inflammation....Read more
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Role of NBD and DBD in P- glycoproteinfunction, a Molecular dynamic simulation
Cancer; Prevention, Diagnosis and TreatmentP-glycoprotein (P-gp) is an ATP-binding cassette (ABC) transporter which belongs to multidrug resistance pump super fami...Read more
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Current Advances in the Genetic Basis of Rheumatoid Arthritis
Medical GeneticsRheumatoid arthritis (RA) is a chronic inflammatory disease characterized by a distinctive pattern of joint involvement ...Read more
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Frequency of Binding Site at C-Terminal of Helicobacter Pylori CagA Separated from Gastric Tissue Biopsy of Patients with Gastroduodenal Disorders in Shafa Hospital in Khorramabad
Microbiology and Infectious DiseasesHelicobacter pylori (H. pylori) is a gram-negative, microaerophilic bacterium in gastric mucosa. It has a helical shape...Read more
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Study of HER2 gene expression in AGS cell line after treatment of cells with Crocus sativus (Iranian Saffron) extract
Cancer; Prevention, Diagnosis and TreatmentThe study of HER-2 gene in cancers, especially gastric cancer, is of great importance. This gene, has been shown to inc...Read more
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Evaluation of toxicity of functionalized graphene with ginsenoside Rh2, Lysine and Arginine on RBCs, blood coagulation and cardiovascular tissue: In vitro and In vivo study
Nano-Biotech MedicalIn this study, blood and cardiotoxicity of functionalized graphene with ginsenoside Rh2 (Rh2), Lysine and Arginine was e...Read more
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THE TOLE OF PROBIOTICS IN PUBLIC HEALTH
Nutrition and HealthIn the last decade, we have seen dramatic changes in understanding the role of foods in improving human health. scientif...Read more
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Survaey polymorphism rs 866751883 ADAM2 gene infertile men referred to infertility treatment centers in East Azerbaijan which under treatment with IUI (Intrauterine Insemination)
Medical GeneticsOne of the most important genes in human infertility is ADAM2 gene. The gene function is the important in the process of...Read more
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The role of long non-coding RNAs in hematologic malignancies
Cancer; Prevention, Diagnosis and TreatmentLong noncoding RNAs(lncRNAs) are a novel heterogeneous group which refer to non-coding RNA molecule ranging in length fr...Read more
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Discrimination of Leishmania species by Arginine permease gene AAP3as a suitable molecular tool for detection and genetic proximity analysis
Microbiology and Infectious DiseasesLeishmaniasis presents itself in different clinical manifestations such as: visceral Leishmaniasis, Cutaneous Leishmania...Read more
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The Effect of Vitamin D on Diabetes Mellitus: A Systematic Review
Metabolism and Metabolic Diseases: Diabetes Mellitus is a common metabolic and non-infectious disorder that affects around 346 million people worldwide w...Read more
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The Approaches for Salivary Glands (SGs) Regeneration: a review
Stem cell and Medical ApplicationsSaliva is secreted from three pairs of major SGs and 100–800 minor SGs and plays a vital role in oral and general heal...Read more
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Evaluation of cytotoxicity, viability and induced oxidative stress by Nickel (II) complex of thiosemicarbazone
Cancer; Prevention, Diagnosis and TreatmentThiosemicarbazones and their metal complexes have significant biological activities including anticancer, antibacterial,...Read more
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The effect of Chlorogenic acid on Insulin, GIP and GLP-1 level in healthy humans: A systematic review
Nutrition and HealthAccording to previous studies, there are different supplements in order to prevent and treat diabetes. These studies sho...Read more
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Association of selenoprotein S expression and its variants with metabolic syndrome in subjects with cardiovascular disease
Metabolism and Metabolic DiseasesSelenoproteins S (SELS or VIMP) may regulate cytokine production, and thus play a key role in the control of the inflamm...Read more
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Comparative miR34a expression profile analysis in tumor and normal tissues of patients with colorectal cancer
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer is a type of prevalent cancers in populations and allocates numbers of mortality. Recently, researcher...Read more
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Examination of mutations in QRDRs in ParC, ParE genes Salmonella Clinical Examples of Zahedan Hospitals
Microbiology and Infectious DiseasesSalmonellosis is a major public health problem worldwide. Although most Salmonella infections result in mild self-limiti...Read more
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Anticancer effect of Quercus infectoria aqueous leaf extracts against colon cancer HT29 cell line
Cancer; Prevention, Diagnosis and TreatmentIn traditional medicine and previous studies, Quercus infectoria plants are a well-known and have been suggested as a ca...Read more
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Comparative study of Calendula officinalis and Matricaria chamomilla extracts on Cisplatin induced neuropathic pain
Cancer; Prevention, Diagnosis and TreatmentCisplatin is one the most important cancer chemotherapy agents that uses for two decades. Neuropathic pain induced by th...Read more
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The role of oils in breast cancer in women (systematic review)
Cancer; Prevention, Diagnosis and TreatmentAbout one-third of cancers may be related to diet, along with lifestyle and physical activity. International data show t...Read more
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The role of lipids in the pathogenesis of Human T-cell leukemia virus-1 (HTLV-1) infection: a review of literature
Microbiology and Infectious DiseasesHuman T cell lymphotropic virus-1 (HTLV-1) is an oncogenic retrovirus which can cause adult T-cell leukemia lymphoma (AT...Read more
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The Effects of MicroRNAs on Bone Regeneration and Differentiation
Medical GeneticsOne of the promising approaches for osteoporosis treatment is bone regeneration. In this case, several therapeutic optio...Read more
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Influence of matrix rigidity on the differentiation of mesenchymal stem cells in response to TGF-β
Stem cell and Medical ApplicationsBone marrow human mesenchymal stem cells (hMSCs) are an appreciated cell source for tissue engineering and regenerative ...Read more
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Therapeutic effects ellagitannin on non communicable diseases
Nutrition and HealthToday, due to the complications caused by the treatment with chemical drugs, the scientists focus on to use of complemen...Read more
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Simple solution to prevent prostate cancer
Cancer; Prevention, Diagnosis and TreatmentMen above fifty five years old are at high risk for malignant prostate cancer. Currently surgery is the only treatment a...Read more
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Design, production and purification of polyclonal antibodies against recombinant human erythropoietin antigens for immunological investigation of pharmaceutical and clinical samples
Nano-Biotech MedicalIn this research, the primary antibody against erythropoietin is produced by injecting pure recombinant human erythropoi...Read more
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Berberine induced cell death of human colon cancer HT-29 through mediating of PARP
Cancer; Prevention, Diagnosis and TreatmentBerberine is an isoquinoline which has many various pharmacological activities, including anticancer activities. Poly (A...Read more
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Doxycycline loaded Kefiran nanofibers: cell viability improvement
Nano-Biotech MedicalDoxycycline (DOXY) is a second generation tetracycline antibiotic with extensive usage. High concentration of DOXY might...Read more
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Association of Cytochrome P450 2C19 (CYP2C19) gene polymorphism and the risk of endometriosis in Iranian population
Women and Reproductive HealthEndometriosis is a chronic disease that is characterized by the occurrence of endometrial glands and stroma outside the ...Read more
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The prevalence of adeABC encoding genes among Acinetobacter baumannii carbapenem resistant clinical isolates.
Microbiology and Infectious DiseasesAcinetobacter baumannii is the important cause of nosocomial infections worldwide due to its propensity to rapidly acq...Read more
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Cytotoxicity study of nanoparticles containing aminoglycosides
Nano-Biotech MedicalAminoglycosides are a bunch of antibiotics that inhibit the synthesis of protein in bacteria and lead to eradication of ...Read more
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Molecular screening for E255K mutations in Imatinib Resistant-CML
Medical GeneticsChronic myelogenous leukemia (CML) is a clonal disease that kind of hematopoietic stem-cell cancer. A significant number...Read more
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A foundation for universal T-cell based adoptive immunotherapy
Cancer; Prevention, Diagnosis and TreatmentThe patient-specific autologous therapy could be a significant limiting factor in the large-scale exploitation of CAR te...Read more
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Identifying Linking Mechanisms of Allergy and Cancer
Cancer; Prevention, Diagnosis and TreatmentAllergy and cancer are prevalent diseases and cause a lot of morbidity and mortality. In recent years, many studies have...Read more
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Evaluation of serum lipid profiles and oxidative stress indices in sprayer workers
Metabolism and Metabolic DiseasesDirect or indirect contact with pesticides and toxins leads to some biochemical changes, including increasing the produc...Read more
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Non-syndromic obesity in infertile men and structural chromosomal abnormalities
Medical GeneticsObesity is commonly classified into subgroups depending on suspected etiology: monogenic obesity (extremely severe obesi...Read more
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Cucurbitacin D from Ecballium elaterium (L.) A. Rich upregulates BCL-2 gene in human gastric cancer cell line AGS
Cancer; Prevention, Diagnosis and TreatmentMedicinal plants are potential sources of new drugs and natural therapies based on them are becoming increasingly import...Read more
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Design and evaluation of a selective delivery system to induce antimiR-155 function
Nano-Biotech MedicalDeveloping RNA/DNA aptamer-miRNA chimera represents an effective approach in targeted gene therapy of cancer. In additio...Read more
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Effect of Zinc Oxide Nanoparticles on expression of proapoptotic BAX and Bcl-2 in Testicular Tissue of NMRI Adult Mice
Nano-Biotech MedicalZinc oxide nanoparticles have numerous applications in medicine and industry. These materials are delivered to the tissu...Read more
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Isolation and identification of probiotic bacteria from human milk
Microbiology and Infectious DiseasesBackground: Breast milk is the best nutritional supplement during the first few months of the baby's life. It contains v...Read more
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Investigating the relationship between metacognitive beliefs, and premenstrual syndrome and depression caused by that, in female students studying at Tehran University of Medical Sciences
Women and Reproductive HealthThe purpose of this research was studying the relation between meta-cognitive beliefs on premenstrual syndrome and depre...Read more
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Investigating the role of Nanodrugs in the treatment of Candida and Aspergillus infectons
Microbiology and Infectious DiseasesInvasive fungal infections are a major problem for immunocompromised patients in intensive care units. Morbidity and m...Read more
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The nutritional benefits of Pistacia atlantica
Nutrition and HealthPistacia Atlantica Mutica is a genus of the family Anacardiaceae which consist of different parts such as fruit, leave a...Read more
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Antibacterial properties of saffron
Microbiology and Infectious DiseasesSaffron is a small herb of the Welsh family. This is a plant with spherical onions which surrounded by a brown membrane....Read more
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Sun protection factor (SPF) determination of sericin cream and niosomal gel
BeautySericin is a protein extracted from silk and has antioxidant, antimicrobial, antineoplastic, wound healing and moisturiz...Read more
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Investigating the incidence of cardiovascular in patients with ercutaneous coronary interventionin Bandar Abbas Shahid Mohammadi Hospital
Metabolism and Metabolic DiseasesPCI(Percutaneous coronary intervention) is one of the most common mode of re vascularization. so According to the impo...Read more
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case report of Albinism with pseudo dominant inheritance
Medical GeneticsOculocutaneous albinism type 1 is characterized by hypopigmentation of the skin and hair and the distinctive ocular chan...Read more
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Design, modeling and simulation of a novel immunotoxin structure affective against gastrointestinal malignancies
Cancer; Prevention, Diagnosis and TreatmentGastrointestinal malignancies comprise a remarkable proportion of cancer deaths each year. Although many drugs have been...Read more
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The role of Human Papillomavirus Vaccination on cervical cancer: A systematic review
Cancer; Prevention, Diagnosis and TreatmentAccording to International agency for research on cancer (IARC), cervical cancer is the forth reason of death because of...Read more
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In silico cancer therapy by using genome editing tool: CRISPR/Cas9
Cancer; Prevention, Diagnosis and TreatmentGiven the fact that cancer today has a broad spectrum of diseases in the populations, and also by relying on the fact th...Read more
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Association between Heat shock protein 70 gene polymorphism and risk of multiple sclerosis in Iranian population
Medical GeneticsMultiple sclerosis (MS) is a chronic disease of the central nervous system and one of the most common causes of neurolog...Read more
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Autism spectrum disorder (ASD) and cancer: both share same genes but different outcomes.
Medical GeneticsAutism spectrum disorder (ASD) is a neurodevelopmental disorder and it is characterized by social and communication prob...Read more
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The impact of the vaginal probiotic lactobacillus on the prevention and treatment of cervical cancer
Cancer; Prevention, Diagnosis and TreatmentToday, cervical cancer is the second most common cancer after breast cancer among women and it`s considered dangerous ...Read more
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Molcular Detection of Mupirocin Resistance in Staphylococcus aureus
Microbiology and Infectious DiseasesStaphylococcus aureus has become the most common cause of hospital acquired infections over the last few decades. The ba...Read more
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Blood porphyrin fluorescence peaks and its diagnostic value for early colorectal cancer (CRC) detection
Cancer; Prevention, Diagnosis and TreatmentPorphyrins are precursors of Heme metabolism. Any metabolic disorder like cancer can highly affect their level. Since th...Read more
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Differentiation of mesenchymal stem cells to insulin-producing cells with of use to basic culture medium
Metabolism and Metabolic DiseasesDiabetes mellitus type 1 is a form of diabetes mellitus in which not enough insulin is produced. To this date, no defini...Read more
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Cytotoxic evaluation of cumin essential oil on breast cancer cell line (MCF-7)
Cancer; Prevention, Diagnosis and TreatmentCancer can be considered as one of the genetic diseases that reduces the mortality rate in cancer cells in this disease....Read more
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Impact of CYP3A5 and CYP3A4 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia and treatment response
Medical GeneticsCYP3A5 and CYP3A4 are the members of the CYP3A gene family which metabolizes 50% of therapeutic drugs and steroid hormon...Read more
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TYCSB culture media reliability for S. mutans isolation
Microbiology and Infectious DiseasesAlthough the clinical significance of dental caries is well recognized, the exact etiology of the condition is not under...Read more
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Prevalence of septicemia in Intasive care unit and Internal medicine wards patients in Rajaee Hospital of Karaj
Microbiology and Infectious DiseasesSepticemia or blood infections is One of the most important causes of death in patients hospitalized in different parts...Read more
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Effect of genistein associated with agonist (17-β estradiol) on the viability and apoptosis of human hepatocellular carcinoma HepG2 cell line
Cancer; Prevention, Diagnosis and TreatmentBackground: One of the most lethal cancers is Hepatocellular carcinoma (HCC). Genistein (GE) is a choice compound for tr...Read more
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Diet and lifestyle habit imoact on bone density in postmenopausal women
Nutrition and HealthMenopause is the stage of a woman's life, typically between the ages of 45 and 55, when she stops having menstrual perio...Read more
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Identification of bacterial agents of urinary tract infection in patients referred to a laboratory during six months
Microbiology and Infectious DiseasesEstablishing a diagnosis of symptomatic UTI requires a patient to have symptoms and signs of a UTI and laboratory tests ...Read more
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Frequency of TEM and SHV genes in the strains of Acinetobacter producing broad-spectrum isolated ß-lactamases from Zahedan patients by PCR method
Microbiology and Infectious DiseasesAcinetobacter baumannii is one of the most important factors in hospital infections, and its Colonization rate in hospit...Read more
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Wound healing effect of Tea tree oil on Methicillin Resistant Staphylococcus aureus (MRSA) : an Animal Study
Microbiology and Infectious DiseasesTea tree oil (TTO), or melaleuca oil, is an essential oil with a fresh camphoraceous odor and a color that ranges from p...Read more
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evaluation of anti-mullerian hormone in daughters of women with polycystic ovary syndrome
Women and Reproductive HealthPolycystic Ovary Syndrome(pcos) is one of the most common endocrine diseases among women during their fertility years . ...Read more
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Relation between Resilience and Psychiatric Disorders in Patients with Aids in Bandar Abbas Center for Behavioral Diseases
Nutrition and HealthThe AIDS process is very complex and can significantly affect the physical, social, spiritual and psychological health o...Read more
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Silver nanoparticles potential as an adjuvant in antimicrobial therapies against multidrug resistant bacteria
Microbiology and Infectious DiseasesThe emergence and rapid spread of multidrug-resistant (MDR) isolates of pathogenic bacteria causing nosocomial infection...Read more
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Investigating the effects of saffron and melatonin with radiotherapy on viability of Hela cells
Cancer; Prevention, Diagnosis and TreatmentNowadays, a lot of people in the worldwide dead because of cancer. Despite much research in this area, there is still no...Read more
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Classification of Genes Related to Infectious Disease: New Hybrid Method for High Imbalanced Data Sets
Medical GeneticsGene functionality explorations has a great importance in health science research. Developing gene classifiers having ac...Read more
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The effects of vitamin D3 supplement on clinical course of patients with migraine
Nutrition and HealthMigraine is one of the most common headaches all around the world including Iran. Considering that some studies have sho...Read more
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Investigation of synergies effects of albumin- amino penicillin on Staphylococcus aureus MRSA
Nano-Biotech Medicalduring the recent decades, Nanotechnology has entered the field of drug industries and importance of nano-drugs in curin...Read more
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Role of Immune system in treatment of cerebral palsy by stem cells
Stem cell and Medical ApplicationsCerebral Palsy (CP) is known as a non-progressive brain disorder that occurs due to injuries or abnormalities in develop...Read more
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Investigation of epigenetic effects of Disulfiram on the demethylation of RASSF1A gene promoter in breast cancer cell line MCF-7
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the most common type of cancer among women with very high mortality rates in the world. Genetic and epi...Read more
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Antiangiogenic Effect of Endostatin-derived Peptides on a Mouse Model of Colon Cancer
Cancer; Prevention, Diagnosis and TreatmentColon Cancer is among the most common malignancies worldwide. Angiogenesis is the formation of new microvasculature thro...Read more
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Biosynthesis of Silver nanoparticles using water extract of Ziziphus spina_cheristi Leaves
Nano-Biotech MedicalSilver nanoparticles (AgNPs) have been widely used as an antiseptic against a wide range of microorganisms. The goal of ...Read more
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Investigation efflux pump -activated fluoroquinolone resistance in pseudomonas aeroginosa multi drug resistance isolates by CCCP inhibitor
Microbiology and Infectious DiseasesPseudomonas aeruginosa is the third cause of nosocomial infections after Staphylococcus aureus and E. coli .One of the p...Read more
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Antibody-drug conjugates; a Novel class of cancer treatment
Cancer; Prevention, Diagnosis and TreatmentOne of the most effective therapeutic agents used in targeted cancer therapies is antibody. Due to lack of permeability ...Read more
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Comparative investingation of effects of the agricultural pesticides (diazinon and chlorpyrifos) on spermatogenesis in male BALB/c male mice
Nutrition and HealthDiazinon and chlorpyrifos are kind of organophosphate toxins used for agricultural pests. These toxins control acetylch...Read more
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Anti-anxiety effects of sinapic acid in NMRI mice
Nutrition and HealthThe present study investigated the anxiolytic effects of sinapic acid on NMRI mice behavior in the elevated plus-maze (E...Read more
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Molecular mechanism of alpha-2 adrenergic receptors in locus Coeruleus
Medical GeneticsPain is one of the most common forms of psychological stress and the most common phenomenon in medical science. Analgesi...Read more
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Performing PGD combined with HLA typing on more than 100 blastomeres
Medical GeneticsPreimplantation genetic diagnosis (PGD) is an option for carrier couples who want to assure their child’s health regar...Read more
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Bioinformatics evaluation of hsa-miR-548g related to single nucleotide polymorphism (rs1803622) of GAPDH gene in patients suffering from breast cancer
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is one of the most prevailing cancer among females. GAPDH gene is located on chromosome l on position of G...Read more
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Study of matrix metallo proteinase (MMP)-9 gene & its phylogeny tree as a critical gene in metastases
Medical GeneticsThere has been a clear connection between MMPs,ECM degradation & cancer cell invasion. Matrix metalloproteinase(MMP)-9, ...Read more
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Evaluating the genetic variations of ARPT1 gene in infertile men with abnormality in sperm head morphology referring to Royan institute.
Medical GeneticsThe evaluation of human sperm morphology is a controversial aspect of the semen analysis for the determination of male...Read more
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Evaluation of selenium & zinc levels and antioxidant power in serum of women with endometriosis before and after administration of N-Acetylcysteine
Women and Reproductive HealthEndometriosis is characterized by the presence of glands and endometrial stroma outside the uterine and affects approxim...Read more
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Non-muscle Myosin Heavy Chain 9 Gene (MYH9) Polymorphism (rs4821481) is Associated with Urinary Albumin Excretion in Iranian Diabetic Patients
Medical GeneticsMyosin heavy chain 9 (MYH9) gene polymorphisms have been implicated in a different type of renal disease as well as neph...Read more
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Cloning, expression and functional assay of bacterial Uricase, a medical enzyme for the treatment of chronic gout
Metabolism and Metabolic DiseasesUricase, which is originated from a variety of organisms including bacteria, is an important agent for tracing of Uric A...Read more
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Serum levels of testosterone, dehydroupiandrosterone sulfate, luteinizing hormone and follicular stimulus hormones in offspring of women with polycystic ovary syndrome
Women and Reproductive HealthPolycystic Ovary Syndrome(pcos) is one of the most common endocrine diseases among women during their fertility years . ...Read more
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study of microbial quality of some food samples
Nutrition and Healthbacterias are considered as the most important factor to cause infection and food poisoning ,so that microbial contamina...Read more
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A genetic variant in Multiple drug resistance gene is associated with poor prognosis of patients with esophageal squamous cell carcinoma
Cancer; Prevention, Diagnosis and TreatmentEsophageal squamous cell carcinoma (ESCC) is one of the causes of death from cancer. Several genetic variants in the 7q2...Read more
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Design and evaluation of a colorimetric method for rapid determination of minimal inhibitory concentration of the bacteria belonging to Enterobacteriace
Microbiology and Infectious DiseasesIsolation of antibiotic resistant pathogenic bacteria in clinic may pose the serious problems. So a rapid method capabl...Read more
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Evaluation of Interleukin 10 Gene Promoter Polymorphisms of -592A/C and -1082A/G Region Among Obese Individuals with Type 2 Diabetes in Alborz Province
Metabolism and Metabolic DiseasesToday diabetes is one of the most prevalent noncontagious diseases around the world. There is strong evidence showing in...Read more
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Effects of Rosmarinic acid on oxidative stress and total antioxidant capacity in vivo study
Metabolism and Metabolic DiseasesDiabetic disease is characterized by chronic hyperglycaemia. Numerous studies have shown that in diabetes mellitus, ther...Read more
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Invitro Effect of Probiotics, Paraprobiotic and Postbiotics of Locally Isolated Lactobacillus casei strains on Colon Cancer Cell Lines
Microbiology and Infectious DiseasesA number of lactic Acid Bacteria (LAB) produce bacteriocin which are bioactive peptides active against a number of path...Read more
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The role of cabergoline medicine in treating Cushing's syndrome: A systematic review
Metabolism and Metabolic DiseasesCushing's syndrome is an endocrine disorder caused by the excessive production of corticosteroid hormones and adrenocort...Read more
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Effect of Staphylococcus aureus isolates in food samples on hep2 cell line
Microbiology and Infectious DiseasesStaphylococcus aureus produces a range of protein-rich toxins and also extracellular pathogens that contribute to bacter...Read more
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One Step Toward Normal Heart Beat By Biological Pacemaker
Medical GeneticsCardiac electrical impulses are generated in sinoatrial node (SAN) which establishes spontaneous action potentials. SAN ...Read more
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Gene expression profiling of the 8q22-24 position in human breast cancer: TSPYL5, MTDH, ATAD2 and CCNE2 genes are implicated in oncogenesis, while WISP1 and EXT1 genes may predict a risk of metastasis
Cancer; Prevention, Diagnosis and TreatmentGene expression profiling has been suggested to predict breast cancer outcome. The prognostic value of the 8q22 24 posit...Read more
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Marine Biotechnology in public health and food safety
Nutrition and HealthSea and oceans make up more than 70 percent of the Earth's surface, and on the other hand, more than 80 percent of livin...Read more
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Investigating the role of exon7 axin2 in colorectal cancer (Laboratory and bioinformatics studies)
Cancer; Prevention, Diagnosis and TreatmentIn Iran, colon cancer is the third most common cancer. WNT pathway changes are commonly reported in this cancer. Among t...Read more
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Effect of Biochanin A on retinal angiogenesis and inflammation in STZ induced diabetic rats
Metabolism and Metabolic DiseasesWithout proper medication for the treatment of diabetic retinopathy (DR), retinal cells become malnourished and degenera...Read more
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An investigation on the structure and function of the cell surface breast-specific antigens for development a new generation of immunotoxins
Cancer; Prevention, Diagnosis and TreatmentBreast cancer with heterogeneous features in morphology, clinic, and responses to therapeutic options, is one of the mos...Read more
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Therapeutic effect of Human Tumor Necrosis Factor Receptor-2 on collagen -induced arthritis in Balb/c mice
Metabolism and Metabolic DiseasesRheumatoid arthritis (RA) is a chronic, systemic, immune-mediated inflammatory disease associated with decreased life ex...Read more
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Evaluation of cytotoxicity of rainbow trout extracts (Oncorhynchus mykiss) on gastric cancer cell line (AGS)
Cancer; Prevention, Diagnosis and Treatmentrainbow trout due to high levels of essential fatty acids, omega-3 has been identified as one of the important factors i...Read more
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Explaining Women's Views on Cervical Cancer: A Qualitative Study
Cancer; Prevention, Diagnosis and TreatmentCervical cancer is the second most common cancer in the world , Which, if detected and treated at early stages, is almo...Read more
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Investigation of cytotoxicity, cell cycle and induction of apoptosis by methyl-thiosemicarbazone complex with Cu2+ in K562 cell line
Cancer; Prevention, Diagnosis and TreatmentThiosemicarbazone compounds have previously been considered as a new series of potent apoptosis-inducing agents. In the ...Read more
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The effect of Rosa canina extract on Bax gene expression in gastric adenocarcinoma cell line(AGS)
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is the most common cancer in the world. It occurs as a result of many factor and there is massive invest...Read more
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Neural System Biomarkers
Stem cell and Medical ApplicationsBiomarkers are widely used by physicians, Labradoreans, and scientists. Popular utilization of biomarkers in vivo and in...Read more
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Role of MicroRNAs in Multiple Sclerosis
Medical GeneticsMultiple sclerosis (MS) is an autoimmune neurodegenerative disease in which the body’s natural defense system attacks ...Read more
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NRG1 expression changes in Autism spectrum disorder and play role in executive functions abnormalities
Medical GeneticsAutism spectrum disorder (ASD) is a pediatric heterogeneous psychiatric and neurodevelopment disorder with social and co...Read more
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NEW CONCEPTS IN THE IMMUNOPATHOGENESIS OF MULTIPLE SCLEROSIS
Medical GeneticsMultiple sclerosis (MS) is a chronic disorder of the central nervous system characterized by autoimmune inflammation, de...Read more
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The influence of lactobacillus fermentum cytoplasmic extract, isolated from traditional cheese (kuzeh) on the expression of p53 gen in K562 cancerous array via a quantitative Real time PCR method
Cancer; Prevention, Diagnosis and Treatmentthe probiotics are able to induce apoptosis in cancerous cells. chronic myelocytic leukemia (cancerous array of K562) is...Read more
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Effect of Valproic Acid on Proliferation and Apoptosis of Colon Cancer HT 29 Cell Line
Cancer; Prevention, Diagnosis and TreatmentThe structure of chromatin is made up of DNA, histones, and non-histone proteins with the basic repeating unit, nucleoso...Read more
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Study of DNA methylation pattern in sf-1 gene promoter region in endometriosis tissue samples of women in north west of Iran
Medical GeneticsEndometriosis is an estrogen-dependent inflammatory disease. Its defining feature is the presence of endometrium-like ti...Read more
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The effect of diet in preventing of colorectal cancer: A systematic Review
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer (CRC) is the third most commonly diagnosed cancer in worldwide and it is established that diet has an ...Read more
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EXPRESSION OF AN ANTIBODY FRAGMENT (SCFV) AGAINST AMYLOID-BETA USING T7 PROMOTER IN FED-BATCH CULTIVATION MODE
Microbiology and Infectious DiseasesIn the current investigation, the expression yield and solubility of Aβ antibody was analyzed using T7 promoter in fed-...Read more
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Evaluation of the HLA-B46 Allelic frequency in the patients with spondyloarthritis syndrome in zanjan province
Medical GeneticsSpondyloarthritis is a group of multi-systematic disorders that has been created by spinal features, peripheral jointsan...Read more
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Recombinant fibroin containing the RGD motif enhances limbal mesenchymal stromal cell adhesion and proliferation
Stem cell and Medical ApplicationsAt the periphery of the cornea, in a region called the limbus, exists a population of stromal progenitor cells termed li...Read more
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Chimeric Antigen Receptors (CARs) as a powerful approach for cancer therapeutics
Cancer; Prevention, Diagnosis and TreatmentT-cells have the potential to extirpate abnormal cells. The genetic modification and characterization of T-cells with ch...Read more
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Optimization of the best concentration of Aloe vera extract for treating gastric cancer cells in order to reduce HER-2 gene expression
Cancer; Prevention, Diagnosis and TreatmentHER2 is a glycoprotein that has tyrosine kinase activity and plays an important role in guiding growth signals. Its expr...Read more
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Effect of Hypiran on the oxidative stress responses in experimental autoimmune encephalomyelitis
Nutrition and HealthExperimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis. The hallmark of this disease i...Read more
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Evaluation of antioxidant activity and cytotoxicity of an ethanol extract of leaves, fruits and calyx of Physalis alkekengi on human lung cancer A549 cell line
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the most common cancers and chemotherapy cancer treatment is one of the methods, but because of the lack ...Read more
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Impact of GSTP1 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia
Cancer; Prevention, Diagnosis and TreatmentGenetic variation influencing individual susceptibility to chemical carcinogens is one of the main factors leading to ca...Read more
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Study on protein of leech saliva of Hirudo Oreintalis, Utevsky & Trontelj 2005 in different ages
Nutrition and HealthMedicinal leech, during feeding, enter in host body many bioactive substances that often contain proteins and peptides. ...Read more
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The effect of ziziphora extract on the expression of the Claudin_1 gene in the AGS cell line
Cancer; Prevention, Diagnosis and TreatmentClaudins are the main structural and functional proteins of tight junctions in epithelial cells. The altered expression ...Read more
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The effects of sodium butyrate on the expression of HDAC8 gene in HT-29 colorectal cancer cell line
Cancer; Prevention, Diagnosis and TreatmentSodium butyrate (NaB) is a potent growth inhibitor and initiates cell differentiation for many cell types in vitro. In t...Read more
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Role of Potential tumor marker in several cancer: Diagnostic and Treatment
Cancer; Prevention, Diagnosis and TreatmentTumor markers are substances produced by the tumors or by other cells of the body in response to cancer. They are produc...Read more
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Identifying MicroRNA-mRNA regulatory network in breast cancer sample with drug resistance
Cancer; Prevention, Diagnosis and TreatmentA computational approach to prediction of miRNA targets narrowing down potential target sites for experimental validatio...Read more
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Study of gene expression network in varicose veins disease by microarray expression analysis
Medical GeneticsThere is a strong body of circumstantial evidence which implicates genetics in the etiology and pathology of and venous ...Read more
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Intervention of Dopamine D2 Receptors in Regulating the Serum Lipid Profile in Male Rats under Food Restrictions
Nutrition and HealthStudies have indicated that reduced energy consumption mostly has a significant effect on the reduction of blood lipids...Read more
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Effect of EMF on Semen TBARS Concentration
Women and Reproductive HealthElectrical instruments in human life by development of applications causes new biological phenomenon in this century. Ne...Read more
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Molecular markers in the diagnosis of lung cancer
Cancer; Prevention, Diagnosis and Treatmentlung cancer is the leading cause of cancer-related mortality, one of the main causes of mortality by 2010. There are sev...Read more
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Effect of letrozole as alternative aromatase inhibitor on development of ovarian follicles and uterine changes in adult NMRI mice strain and their infants
Microbiology and Infectious DiseasesLetrozole is used as an aromatase inhibitor, to increase ovulation induction. This drug is usually prescribed for patien...Read more
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Food Patterns and Framingham Risk Score in Iranian Adults: Tehran Lipid and Glucose Study: 2005-2011
Nutrition and HealthHealthy dietary habits can prevent cardiovascular diseases (CVD). The aim of the present study was to investigate the as...Read more
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The evaluation of recombinant beclin1 effect on cervical cancer in mice model
Medical GeneticsOne of the factors that play a direct role in suppressing cancer cells is the pathway of autophagy and apoptosis that is...Read more
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Whole-Exome Sequencing Identifies R1279X of MYH6 to be Associated with Congenital Heart Disease and Other Malformations
Medical GeneticsMyosin VI, encoded by MYH6, is expressed dominantly in human cardiac atria and plays consequential roles in cardiac musc...Read more
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Apoptotic effect of anticancer drug Alimta on A549 calls is independent of HMGB1 release
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the leading cause of cancer-related deaths worldwide. Alimta is a new-generation antifolate drug, approv...Read more
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Effect of Praziquantel Drug on Prevention of Afflicting Dogs with Cestode Echinococcus Granulosus
Microbiology and Infectious DiseasesAwareness of the impact range of praziquantel drug on prevention of afflicting dogs with echinococcus granulosus parasit...Read more
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Assessment of energy and water-soluble vitamins intake in the elderly under health care, Isfahan, Iran
Nutrition and HealthThe B vitamins are essential nutrients to maintain nutritionally healthy body. These water soluble vitamins are critical...Read more
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Distribution of Main Variants in Reactions of Cytotoxin vacA of H. pylori in Gastric Biopsy Specimens
Microbiology and Infectious DiseasesHumans have suffered digestive problems for centuries, and we now know that H. pylori are one of their most important ca...Read more
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The antiproliferative and cell cycle arrest effects of Botox on MCF-7and PC-3 cell line
Cancer; Prevention, Diagnosis and TreatmentBotulinum toxin (Botox) is the most potent biological toxin known to against human life. It can be used as a selective a...Read more
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Stress-induced immobility in male and female rats and its effects on offspring numbers, sex ratios and sexual hormones
Women and Reproductive HealthStress-induced immobility inhibition of reproductive functions and can effect on sexual hormones. Increasing/decreasing ...Read more
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Effects of 5-aza-2ˈ-deoxycytidine and Valproic Acid on Epigenetic-modifying DNMT1 Gene Expression, Cell Growth Inhibition and Apoptosis Induction in Hepatocellular Carcinoma WCH-17 cell line
Cancer; Prevention, Diagnosis and TreatmentIntroduction DNA molecule of the eukaryotic cells is found in the form of a nucleoprotein complex named chromatin....Read more
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the role of genetics in diabetes and its complications
Medical GeneticsThe purposes of writing this article are the significant role of genetics in the onset of diabetes, hoping to be treated...Read more
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Altered miR-335-5p and miR-124-3p expression in gastric cancer
Medical GeneticsGastric cancer (GC) is fourth most common cancer and third leading cause of cancer mortality worldwide. Considerable eff...Read more
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Mediterranean dietary pattern adherence modify the association between FTO genetic variations and obesity phenotypes
Nutrition and HealthThere is an increasing interest in examining whether dietary patterns modify the association of fat mass and obesity ass...Read more
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Medicinal plants in the treatment of infertility
Women and Reproductive HealthInfertility is disability of a couple to reach pregnancy for more than one year despite regular sexual intercourse. The ...Read more
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The Anticancer Effect of Plant Aqueous Extracts of Aloe Vera in Gene Expression Bax and Bcl-2 on Gastric Adenocarcinoma AGS Cells
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is a major cause of cancer death. In terms of incidence is the fourth most common cancer and the second l...Read more
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Silencing of TIM-3 expression by miR-326 affects apoptosis and proliferation of human HL-60 leukemia cell line
Cancer; Prevention, Diagnosis and TreatmentLeukemia Stem Cells (LSCs) are the main reason for drug-resistance and disease relapse in Acute Myeloid Leukemia (AML). ...Read more
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The effects of methanolic soy extract on ovary tissue modification in model of polycystic ovary syndrome as an inflammation state
Women and Reproductive HealthIntroduction and Objective: Chronic low-grade subclinical inflammation has been increasingly recognized as an interposer...Read more
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Modeling premunition for parasites
Microbiology and Infectious Diseases: Here we are interested in premunition that is an immunologic response in host which provides protection toward some pa...Read more
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Combinatorial therapy of anti-Treg vaccine associated with anti-tumor DC vaccine in mice tumor therapy
Cancer; Prevention, Diagnosis and TreatmentRegulatory T cells (Tregs) obviously have a crucial role in attenuation of anti-tumor immune responses. Application of r...Read more
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CLONING AND EXPRESSION OF an antibody fragment (scFv) against PcrV protein of Pseudomonas aeruginosa in fed-batch cultivation mode
Microbiology and Infectious DiseasesPseudomonas aeruginosa is a major cause of hospital-acquired infections, particularly in mechanically ventilated patient...Read more
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Study of HER2 gene expression in AGS cell line after treatment of cells with Crocus sativus (Iranian Saffron) extract
Cancer; Prevention, Diagnosis and TreatmentThe study of HER-2 gene in cancers, especially gastric cancer, is of great importance. This gene, has been shown to inc...Read more
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Induction of apoptosis by silibinin in SKBR3 breast cancer cell line through activation of caspase 3/7
Cancer; Prevention, Diagnosis and TreatmentThe poor prognosis of breast cancer is due to its resistance to the conventional treatments. Therefore, researchers are ...Read more
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Detection of methylated DNA based on graphene quantum dot -DNA interaction
Nano-Biotech MedicalEpigenetics is the study of interaction between genes and their expressed product which is controlled by some specific c...Read more
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Toxic effects of Selenite and need to bio removal of it
Nutrition and HealthSelenium is an important micronutrient for human and animal health, however it is toxic slightly above homeostatic requi...Read more
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Effect of folic acid supplementation on acute effects of trimethoprim/sulfamethoxazole on histopathological changes in the testes of adult male rats
Stem cell and Medical ApplicationsMale infertility has been reported following long-term sulfasalazine use for ulcerative colitis treatment. However, the ...Read more
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Effect of different Electromagnetic fields (EMF) on sperm viability and motility
Women and Reproductive HealthToday, due to the advancement of the level of technology, electromagnetic fields (EMS) from various industries affect...Read more
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Study of DNA binding and cytotoxic activity of a benzochromene derivative
Cancer; Prevention, Diagnosis and TreatmentDNA is currently a target for some of the drugs used in cancer therapy. Among the various treatment strategies for remov...Read more
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Study of Effects of Crushed PLGA Nano-fiber Percentage on The Cell Proliferation in Chitosan-Gelatin-βGlycerophosphate Cartilage Scaffold
Nano-Biotech MedicalArticular cartilage has poor reparative capabilities. So Osteoarthritis is widespread globally in almost 70% of people o...Read more
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Preconditioning of bone marrow-derived mesenchymal stem cells by AdipoRon potentiates cell migration ability, in vitro.
Stem cell and Medical ApplicationsMesenchymal stem cells (MSCs) have represented a great potential in recent stem cell-based therapies as well as regenera...Read more
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isolates from Kermanshah province submitted at National Animal tuberculosis reference Laboratory at Razi institute
Microbiology and Infectious DiseasesTuberculosis is a zoonotic which has long been recognized and is still one of the most life-threatening diseases. Tuberc...Read more
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Epigenetic Mechanisms as Therapeutic Targets
Medical GeneticsEpigenetics, in conjunction with genetic mechanisms, determine the biological fate of cells and living organisms. epig...Read more
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Microencapsulation and double-coating of probiotic bacteria for enhancement of their viability and targeted delivery
Nutrition and HealthThe purpose of this study was to assess the protecting character of double coated beads of alginate-chitosan-Eudragit S1...Read more
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Effect of intracerebroventricular injection of Adenosine on food and fat intake in neonatal chicks
Nutrition and HealthThe present article was aimed to clarify the role of central Adenosine on food intake in neonatal chicks. Adenosine is n...Read more
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Assessment of the dietary intake of Vitamin D and Blood pressure in Elderlies with health care
Nutrition and HealthPopulation studies have demonstrated that there is an inverse association between dietary intake of vitamin D and incide...Read more
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The effect of celastrol on gene expression of TNF-α (Tumor necrosis factor-a) induced by Influenza A virus (PR8/H1N1) in MDCK cells
Microbiology and Infectious DiseasesInfluenza A virus (IAV) can cause acute respiratory distress syndrome, which leading to kill 250000 to 500000 of world ...Read more
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Intelligent Stimuli Responsive Core@Sell Nanobiomaterial: Biomedical Opportunities and Challenges
Nano-Biotech MedicalNanoscale objects are powerful devices in biotechnology medicine and biomedical sciences. They are potential applicants ...Read more
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The effect of Thymoquinone on the Cell Cycle and Tumor angiogenesis Process in human breast cancer cell line, MDA-MB-231
Cancer; Prevention, Diagnosis and TreatmentIn recent years, tendency to use phytochemical compounds has been grown dramatically, and more than 25% of drugs used du...Read more
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Evaluation of Adenovirus in Pseudomonas aeruginosa susceptible keratitis by PCR molecular method
Microbiology and Infectious DiseasesKeratitis is inflammation of the cornea of the eye. In keratitis, microbial agents are important. In the presence of inf...Read more
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Canavan disease: clinical and molecular review
Medical GeneticsCanavan disease is a rare autosomal recessive disorder that predominantly affects the central nervous system with white ...Read more
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Endurance training resulted in significantly greater betatrophin responses compared with resistance training alone, and resistance and endurance exercises combined
Metabolism and Metabolic DiseasesBetatrophin, which recently identified, is a liver and adipose tissue produced hormones that regulates the level of lipi...Read more
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MUC21 as a suitable candidate for immunotoxins development for targeting esophageal cancer
Cancer; Prevention, Diagnosis and TreatmentEsophageal cancer is the world's eighth most common cancer and the sixth most common cause of cancer death in the world....Read more
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Determination of physico-chemical properties of Faecalibacterium prausnitzii EVs
Microbiology and Infectious DiseasesFaecalibacterium prausnitzii is one of the most common human gastrointestinal bacteria that has been shown to have sever...Read more
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The role of artificial intelligence in medical decisions
Nano-Biotech MedicalThe term "artificial intelligence" was used in 1956. There is still no definitive definition of artificial intelligence ...Read more
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LPS Effects on induction of regulatory T cells in peripheral blood mononuclear cells in endometriosis patients
Women and Reproductive HealthEndometriosis is an estrogen-dependent chronic inflammatory disease affecting women in reproductive ages. Regulatory T c...Read more
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Evaluating Anticancer Effects of Tamarix ramosissima on A549 Cells
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the leading cause of cancer death all over the world. Using plant derived materials as folk remedy has be...Read more
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New mutation in hotspit region of APC gene in FAP patient in Guilan province
Medical GeneticsFamilial adenomatous polyposis (FAP) is a colorectal cancer predisposition syndrome characterized by the presence of hun...Read more
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Correlation of umbilical coiling index and HbA1C in gestational diabetes mellitus (one-step strategy).
Metabolism and Metabolic DiseasesGestational diabetes mellitus [GDM] is a prevalent and potentially serious condition which may put mothers and fetuses a...Read more
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Efficacy of Bone Marrow Mesenchymal Stem Cells and an Amniotic Membrane on the Number of Mast Cells and Degranulation in Random Skin Flaps in Rats
Stem cell and Medical ApplicationsSkin flap procedures are usually used in plastic surgery. Failing can follow, lead to the necrosis of the flap. Therefor...Read more
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the effect of crocin on forgetfulness caused by cholestasis in male rats(behavioral , biochemical and genetical )
Metabolism and Metabolic Diseasescholestasis is a condition in which the bile ducts that carry bile from the liver to the intestine to dispose, is blocke...Read more
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MEDITERRANEAN DIET AND METABOLIC SYNDROME IN DIABETIC SUBJECTS
Metabolism and Metabolic DiseasesType 2 diabetes mellitus (T2DM) increases cardiovascular diseases risk and is a key component of metabolic syndrome (Met...Read more
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the relationship between general and abdominal obesity and advanced glycation end products
Nutrition and HealthAdvanced glycation end products (AGEs) are a heterogeneous group of macromolecules that are formed by the non-enzymatic ...Read more
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Investigating the Relationship between Polymorphism of p22phox in Smoker Population with Chronic Obstructive Pulmonary Disease (COPD) and Susceptibility to Disease
Medical GeneticsCOPD (chronic obstructive pulmonary disease) is a slowly progressive condition characterized by airflow limitation, whic...Read more
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Crocin suppresses multidrug resistance in MRP overexpressing ovarian cancer cell line
Cancer; Prevention, Diagnosis and TreatmentCrocin, one of the main constituents of saffron extract, has numerous biological effects such as anti-cancer effects. M...Read more
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The effect of aerobic training with pomegranate juice on glycemic control and lipid profile women with type 2 diabetes
Metabolism and Metabolic DiseasesType 2 diabetes is a common metabolic disease, which is associated with obesity and immobility. The studies have shown t...Read more
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Cloning and expression of recombinant Cecropin A in Nicotiana tabacum L. hairy roots and its antimicrobial properties
Microbiology and Infectious DiseasesCecropins are a group of antimicrobial peptides (AMP) derived from innate immune system of various multicellular organis...Read more
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Preparation and characterization of Nanofibers Using an Electrospinning Technique as ocular drug delivery
Nano-Biotech MedicalFor the treatment of anterior eye segment infections using anti-infective agents, topical ocular application is the most...Read more
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Effect of hydroalcoholic leaf extract of Ziziphora tenuior L. on pain in male rats
Microbiology and Infectious DiseasesZiziphora tenuior is one of the traditional medicinal herbs; the main active chemical composition of this herb is an ing...Read more
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The Expression Profile of ERBB3 and Its Ligand NRG1 on Depressed Patients Investigation in Hormozgan
Medical GeneticsMajor depressive disorder (MDD), also known simply as depression, is a mental disorder characterized can negatively affe...Read more
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Computational analysis and design of crRNA for post transcriptional regulation of metastamiR-10b and metastamiR-126 by CRISPR-C2C2 technique.
Medical GeneticsOne of the important causes of death in cancer patients is metastasis. Recently have been shown that specific group of m...Read more
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Crispr/cas9 a New Approach to Genome Engineering
Medical GeneticsIn 1987, scientists found an acquired immune system in E.coli genome, included series of short repetitive interspaced pa...Read more
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The impact of miR-16 and miR-34a overexpression on the migratory and invasive potential of breast cancer cells
Cancer; Prevention, Diagnosis and TreatmentBreast cancer (BC) is the most frequent type of cancer and a main cause of cancer-related deaths among women worldwide. ...Read more
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Neuroprotective nature of adipokine resistin in the early stages of focal cerebral ischemia in a stroke mouse model
Metabolism and Metabolic DiseasesThe goal of the present study was to test the dose-dependent and time-dependent effects of mouse recombinant resistin in...Read more
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Evaluation of Adiponectin Hormone in Diabetic and Non-diabetic Patients
Metabolism and Metabolic DiseasesAdipose tissue is currently considered as a hormonally active system in the control of metabolism and not only as a stor...Read more
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Assessment of Tuberculous arthritis using molecular technique
Microbiology and Infectious DiseasesBacterial arthritis is one of the arthritis diseases known that can rapidly cause joint damage. Among the bacteria caus...Read more
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Evaluation of gonadotropin hormones in non-obstructive azoospermia patients
Women and Reproductive HealthInfertility refers to the inability of couples to achieve a successful pregnancy after a year of sexual intercourse with...Read more
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Down regulation of Bcl2 and up regulation of Bax during 2-NDC mediated apoptosis in Acute Promyelocytic Leukemia NB4 cells
Cancer; Prevention, Diagnosis and TreatmentDithiocarbamates have been known as important chemical synthetic compounds for treatment of cancer....Read more
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An Evaluation of Tissue Destruction Time in Phrenic Nerve after Death and Counting the Number of Nerve Fibers in C3, C4 and C5 Branches
Cancer; Prevention, Diagnosis and Treatmentمقدمه اعصاب فرنیک چپ و راست، محرک اصلی عضلة دیافراگم میباشند( .)5ای...Read more
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The effect of Bioactive glass on Adipose-derived MSC osteogenesis in 3D cultures
Stem cell and Medical ApplicationsRegenerative medicine is an emerging field of biotechnology that combines various aspects of medicine, cell and molecula...Read more
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Ginseng For Improving The Quality Of Life In People With Cancer and Fatigue- A Systematic Review
Cancer; Prevention, Diagnosis and TreatmentBackground and purpose: An important issue in cancer health care is the improvement in quality of life (QoL). Physicians...Read more
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The effects of nano-liposomes containing curcumin on the lung cancer cell line.
Nano-Biotech MedicalLung cancer is one of the most common and malignant cancer in both sexes. The prevalence and spread of cancer in iran an...Read more
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Recent study about Genetics of Human Obesity
Medical GeneticsObesity has become a global epidemic and contributes to the increasing burden of type 2 diabetes, cardiovascular disease...Read more
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Berberine induced apoptosis of HT-29 cells through mediating of miR-21
Cancer; Prevention, Diagnosis and TreatmentBerberine is an isoquinoline that can be extracted from many medicinal herbs. microRNAs (miRNAs) are small non-coding RN...Read more
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Effect of Crocin on mitochondrial biogenesis and Oxidative stress in the Striatum of Cholestatic rats
Medical GeneticsOxidative Stress and increment of Mitochondrial Reactive Oxygen Species (ROS) production that occurs in cholestasis whic...Read more
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The effect of mouse recombinant resistin on blood- brain barrier permeability, MDA content and apoptosis in the early stages of focal cerebral ischemia in a stroke mouse model
Metabolism and Metabolic DiseasesThe aim of this study was to evaluate the dose-dependent effects of mouse recombinant resistin on blood-brain barrier(BB...Read more
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Antibacterial effects of curcumin encapsulated in micelle nanoparticles on mexX gene expression in ciprofloxacin resistant isolates of Pseudomonas aeruginosa in Guilan
Nano-Biotech MedicalCurcumin, a polyphenolic compound fromturmeric (Curcuma longa) is a pharmacologically safe agent that has antibacterial ...Read more
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Green Synthesis of Tellurium nanoparticles by Streptomyces isolate BH8 isolated from soils of Sarcheshmeh Copper Complex, Kerman, Iran
Nano-Biotech MedicalTellurium nano particles (TNPs) have pharmaceutical, medical, industrial and environmental importance. Tellurium has als...Read more
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Targeting the Brain –Surmounting or Bypassing the Blood–Brain Barrier
Nano-Biotech MedicalTheconstituentsoftheblood–brainbarrier,includingitseffluxtransportersystem,canefficientlylimitbrainpenetrationofpotent...Read more
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Association between Biochemical Markers BHCG in Screening First Trimester of Pregnancy in Women with PCOS
Women and Reproductive HealthPCOS (polycystic ovary syndrome) is a common endocrine system disease among women of reproductive age. Its prevalence in...Read more
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Combination of ultrasonic waves and dynamic shear stress by design of a novel perfusion bioreactor for 3D bone tissue engineering
Stem cell and Medical ApplicationsIt is shown that mechanical loading by ultrasound enhanced cell proliferation and differentiation. The aim of present st...Read more
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Apoptotic Effect of Tamoxifen on Hepatocellular Carcinoma Hep G2 Cell Line
Cancer; Prevention, Diagnosis and TreatmentHepatocellular carcinoma (HCC) is the sixth most common cancer, and the third most common cause of cancer-related death...Read more
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Nephroprotective effect of Lavandula officinalis L. ethanolic extract in alloxan induced diabetic rats
Nutrition and HealthDiabetes mellitus (DM), a metabolic disorder is a major public health problem in both developed and developing countries...Read more
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Synthesis and characterization of Gold Nanoparticles by Isolated Bacterial from Kerman Sarcheshmeh Copper Mine Soil and the study of their cytotoxic properties
Nano-Biotech MedicalThe present study was designed to isolate bacterial strain capable of gold nanoparticles (Au NPs) production followed by...Read more
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Evaluation and comparison of digestion in two traditional and contemporary medicine schools And its effect on the treatment of diseases
Nutrition and HealthProper nutrition is one of the principles of "preserving health" in traditional and contemporary medicine. Wha...Read more
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Gene Bookmarking, a way to detect, predict and control molecular processes
Medical GeneticsGene bookmarking is a mechanism of epigenetic memory for gene expression transmission programs, during cell division. ...Read more
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Prevalence of Cysticercus bovis in Cattle slaughter-house in Piranshahr city, Iran (2011-2115))
Microbiology and Infectious DiseasesCysticercus bovis are the intermediate stage in the life cycle of a human tapeworm (Taenia saginata). Cysticercus bovis ...Read more
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Effects of administration of trimethoprim/sulfamethoxazole and folic acid on ovarian histopathology in adult female rats
Women and Reproductive HealthPrevious studies have reported the antifertility activities of sulfonamides. This study was designed to evaluate the eff...Read more
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Tuberculosis is a common HIV infection, control and treatment
Microbiology and Infectious DiseasesPoints out Pulmonary that more than all the be without lymph node, pylorus , Urinary tract , bones and joints , meninge...Read more
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An investigation on the structure and function of the cell surface lung-specific antigens for development a new generation of immunotoxins
Cancer; Prevention, Diagnosis and TreatmentLung cancer, with common symptoms such as coughing, weight loss and shortness of breath, is a disease via uncontrolled g...Read more
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Gankyrin expression in ovarian cancer and its correlation with clinicopathological parameters
Cancer; Prevention, Diagnosis and TreatmentGankyrin (p28GANK) is a novel oncoprotein which regulates the phosphorylation of retinoblastoma protein (pRb) and degrad...Read more
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A novel role for stem cells in anxiety disorders treatment
Stem cell and Medical ApplicationsAnxiety disorders are the most common mental disorders which has affected one-eighth of the world's population. Patients...Read more
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Comparison of miR-605 expression in normal and tumor tissue samples of patients with colorectal cancer.
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer (CRC) is the third common type of cancer, and is considered as the main cause of cancer deaths in both...Read more
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Production and evaluation of scFvs against HER2 antigen for breast cancer immunotherapy
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is common cause of women death in the world. There is ErBb2/HER2 in 25%-30% breast cancer cases. Trastuzu...Read more
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Interaction of rs783540 of CPEB1 gene in patients with azoospermia
Medical Genetics: Publicly, 90% of fertile couples get pregnant in one year. Therefore, infertility refers to disability in pregnancy, a...Read more
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An update review about stem cell therapy for diabetes mellitus
Stem cell and Medical ApplicationsMesenchymal stem cells (MSCs) are the most widely used stem cells of the human body because of successful isolation, and...Read more
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The effect of berberin on histone H1 in lung cancer A549
Cancer; Prevention, Diagnosis and TreatmentBerberin, a naturally occurring isoquinoline alkaloid, is present in a number of important medicinal plants. Berberin ha...Read more
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RNY12 peptidomimetic increases SH-SY5Y Neuronal Survival Comparable to BDNF
Stem cell and Medical ApplicationsBrain-derived neurotrophic factor (BDNF) activates downstream cell signaling pathways through TrkB receptor and triggers...Read more
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Structural Study of Lysozyme upon Interaction with Plasmonic gold Nanoparticles
Nano-Biotech MedicalRecent advances in nanotechnology have encouraged scientists to design hybrid systems of nanoparticles and biological ma...Read more
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Development and implementation of a novel panel consisting 16 STR markers linked to the HLA-gene-cluster applicable for HLA-typing, PND&PGD
Medical GeneticsPGD (Pre-implantation Genetic Diagnosis) in combination with human leukocyte antigen (HLA) matching, allow not only sele...Read more
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Biosynthesis of Tellurium nanoparticles by Streptomyces isolate B2.1369F
Nano-Biotech MedicalBiosynthesis of Tellurium nano particles (TNPs) has great advantage since it has no chemical contamination in the enviro...Read more
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Evaluation of the interaction between hemoglobin protein and angiotensin-inhibitory peptide by three-dimensional fluorescence method in the absence and presence of low-frequency electromagnetic fields
Metabolism and Metabolic DiseasesMillion people in worldwide are suffering from high blood pressure and related diseases. Over the past two decades, ther...Read more
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Treatment of vitamin D deficiency in pregnancy
Women and Reproductive HealthThe purpose of this study is the importance of Vitamin D in pregnancy and its treatment. Serum levels of Vitamin D in th...Read more
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microRNAs as potential biomarkers in early detection of Breast cancer
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is one of most worrisome health problems in women across the world. Its incidence and mortality have under...Read more
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Application of Nanomaterials in cosmetic industry
BeautyUsing nanotechnology in various fields, like electronics, medicine, and now in cosmetics applications has expanded. Glob...Read more
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Human reovirus destroys liver cancer cell line (Huh-7)
Cancer; Prevention, Diagnosis and TreatmentThe Huh-7 cell line was derived from a liver tumor in a 57-year-old Japanese male patient in 1982. Hepatocellular carcin...Read more
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Frequency of Escherichia coli O157:H7 among children with and without diarrhea stool samples referred to microbiology laboratory of shahid Madani Hospital in KhorramAbad during 2016-2017.
Microbiology and Infectious DiseasesEscherichia coli serotype O157:H7, which has been recognized as a food-borne pathogen occurring worldwide in the recent ...Read more
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Nano ironoxide effects on mouse heart development; a genome wide mRNA level study
Nano-Biotech MedicalNanoparticles have been used for clinical applications such as Hyperthermia, increasing the resolution of magnetic reson...Read more
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A Review of the Fungi Generating the Cellobiose Dehydrogenase Enzyme to Remove Bacterial Biofilms
Microbiology and Infectious DiseasesThe biofilm causes more than 60% of nosocomial infections and 65% human infections. Bacteria in biofilms society are res...Read more
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Progress and Prospect of Nanotechnology in Stem Cells
Nano-Biotech MedicalThe apparition of nanotechnology has paved the way for an obvious understanding of stem cell therapy in vivo and by repe...Read more
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Investigation of C-582 A>G polymorphism at beta globin cluster gene in beta-thalassemia patients
Medical GeneticsThalassemia is the most prevalent monogenic disorder worldwide resulting from the inappropriate production of heme. pati...Read more
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Evaluation of Acholeplasma laidlawii in biologic products by PCR method
Microbiology and Infectious DiseasesContamination of biological products and cell cultures is one of the important problems in producing a good and safe pro...Read more
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The comparative proteomic pattern study of albumin fraction in type I Gaucher Patients with 2 Dimensional Electrophoresis
Metabolism and Metabolic DiseasesThe gaucher disease is the most common type of lysosomal storage diseases that, particularly affects the macrophage cell...Read more
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Dietary intake of antioxidants in elderly: A case-control study in Iran
Nutrition and HealthNutrient deficiencies such as antioxidants are common problems in elderly subjects which can result in different cancers...Read more
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Prevalence of Pediculus capitis among School Children in the Eastern Area of Ahvaz, Southwestern Iran
Microbiology and Infectious DiseasesHead lice are wingless, obligate ectoparasites of humans, which affect millions of children worldwide, especially those...Read more
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Down-Regulation of Bcl-2 and Mcl-1 by MiRNA-15 and 16 Synergistically Enhances the Apoptotic Effects of ABT-199 and Fludarabin in CLL Cells
Cancer; Prevention, Diagnosis and TreatmentMiRNA-15 and 16 can act as a tumor suppressor gene by interfering with Bcl-2 and mcl-1. Studies have demonstrated that o...Read more
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Eradication of Cancer Stem Cells through microRNAs: a conceptual view
Cancer; Prevention, Diagnosis and TreatmentmicroRNAs (miRNAs), as 19-24 nucleotides endogenous non-coding RNAs, are involved in the most cellular processes playing...Read more
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The study of Apolipoprotein E4 allele distribution in parents of Down's syndrome children as a risk factor in Iran
Medical GeneticsDown syndrome(DS) is the most common chromosomal abnormality.The most important factor in DS is increased maternal age s...Read more
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Molecular identification of Aspergillus isolated from livestock feed and poultry using ASAP1 sequencing
Microbiology and Infectious DiseasesThe contamination of livestock feed and poultry with toxic fungi, such as aspergillus in the air and the environment, is...Read more
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Investigation of toxicity effect of 4-Mepgc and 4-No2pgc on the K562 cell line (chronic myeloid leukaemia)
Cancer; Prevention, Diagnosis and TreatmentLeukemia is a particular type of cancer characterized by the failure of cell death or disability in the differentiation ...Read more
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Evaluation of circulating prognostic tumor marker DNA in the blood of brain tumor patients
Cancer; Prevention, Diagnosis and TreatmentRecent evidence suggests that tumor cells may release DNA into the circulation, which is enriched in the serum and plasm...Read more
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Investigation Of Antimicrobial Effect Of Magnetical Silver And Silver-Titanium Dioxide Nanocomposites On Commonly Bacteria Of Urinary Infects
Nano-Biotech MedicalRecently, developed nano composite with highly efficient antimicrobial properties are considered. In this study, A new m...Read more
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CRISPR/Cas9-mediated gene Knockout
Cancer; Prevention, Diagnosis and TreatmentGenome engineering is a novel and powerful tool for biotechnological applications. The development of the Clustered Regu...Read more
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Investigating the Epidemiology of Concussed Patients, Hospitalized in Khatam al-Anbyia and Ali ibn Abi Talib Hospitals in Years 95-96
Microbiology and Infectious DiseasesFrom the point of view of frequency and importance, Brain vascularaccidents take the first place among all the neural di...Read more
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Removal of Nickel (II) From Drinking Water Using Thiol-Functionalized Chitosan
Nano-Biotech MedicalSome heavy metals are the causes of various diseases among humans. Thus, removing heavy metals is necessary in order to ...Read more
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Perineal massage during pregnancy and perineal safety during childbirth
Women and Reproductive HealthIntroduction: Women frequently suffer from perineal trauma during childbirth, especially during the first childbirth. ...Read more
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The Use of Viruses to Treat Cancer
Cancer; Prevention, Diagnosis and TreatmentCancer is an abnormal growth of cells that have lost normal control mechanisms and are able to expand continuously, inva...Read more
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Rapid and cost effective method for the purification of DNA from Streptococcus mutans and other oral microorganisms
Microbiology and Infectious DiseasesOver 325 bacterial species have been cultured from dental plaque. Not all species can be cultured routinely. Thus, consi...Read more
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Rosmarinic acid, a Anti-glycation agent, inhibits protein glycation in vitro
Metabolism and Metabolic DiseasesDiabetes mellitus is one of the most non-communicable diseases and is the fifth leading causes of death in most of the d...Read more
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Evaluation of cytotoxicity of aqueous-ethanolic extract of pineapple on ovarian cancer cells (A2780 cell line)
Cancer; Prevention, Diagnosis and TreatmentToday, the global trend towards the use of herbal medicines for treating diseases has tended, while developed countries ...Read more
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The relationship between serum creatinine and creatinine clearance with the occurrence and severity of coronary artery disease
Metabolism and Metabolic DiseasesCardiovascular diseases are thought to be the most important reason of mortality around the world. Among them coronary a...Read more
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Expression of CD74 in Ovarian cancer
Medical GeneticsOvarian cancer is a cancer that forms in or on an ovary. The pro-inflammatory cytokine migration inhibitory factor (MIF)...Read more
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Evaluation of Catalase (CAT) expression in Acute Myeloid leukemia Patients
Cancer; Prevention, Diagnosis and TreatmentAcute myeloid leukemia is a heterogeneous neoplastic malignancy, that despite considerable progress in many of its molec...Read more
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Application of cold atmospheric plasma in human and veterinary medicine
Microbiology and Infectious DiseasesIn the last few years plasma medicine has completed the transition from a field of research to actual evidence-based cli...Read more
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Sensitivity of levofloxacin in combination with ampicillin-sulbactam and tigecycline against multidrug-resistant Acinetobacter baumannii
Microbiology and Infectious DiseasesDuring the last decades, emergence of antibiotic resistance among A. baumannii has been considered as a worldwide alarm....Read more
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Synergistic Antibacterial Activity of Zinc Oxide Nanoparticles with Cuminum cyminum L. Essential Oil against the Food-Borne Pathogens Salmonella enterica
Nano-Biotech MedicalOne of the ways to control of pathogenic microorganisms in foods is to use preservatives and antimicrobial agents. Diffe...Read more
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Study of properties of Juglans regia plant on women’s health
Women and Reproductive HealthJuglans regia plant is one of Iranian native plants that some of it’s productive types are in Markazi province. The b...Read more
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Operational study of plastination as an alternate method for dissection
Nano-Biotech MedicalSince, two-thirds of the approved Zoology Laboratory syllables, defined by the Ministry of Science, Research and Technol...Read more
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An innovative field of plasma application for medical therapy
Microbiology and Infectious DiseasesPlasma medicine is an innovative and emerging field combining plasma physics, life science and clinical medicine. Recent...Read more
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ISOLATION OF DEHALOGENASE PRODUCING BACTERIA FROM A MARINE ENVIRONMENT THAT CAN DEGRADE 2,2-DICHLOROPROPIONATE (2,2-DCP)
Microbiology and Infectious DiseasesMost halogenated compounds are major environmental pollutants.2,2-dichloropropionic acid is an organochloride herbicid...Read more
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Potentiation of mitomycin C-induced apoptosis by lithium chloride in MDA-MB-231 breast cancer cells
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the principle cause of cancer mortality in females. Mitomycin C (MMC), as a potent antitumor drug, is u...Read more
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Study of gene expression and promoter methylation pattern of AKAP4 as possible breast cancer diagnostic marker candidate
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is an important health issue for millions of women around the world. Recently, a new group of tumor-associ...Read more
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An in vitro study on the cytotoxicity of anticancer drug Mitoxantrone on hematopoietic stem cells of bone marrow
Cancer; Prevention, Diagnosis and TreatmentMitoxantrone (Novantrone®; dihydroxyanthracenedione) is a synthetically designed antineoplastic agent and structurally ...Read more
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Molecular diagnosis of Mycoplasma spp. arthritis by PCR
Microbiology and Infectious DiseasesArthritis is one of the most common inflammatory diseases. It is characterized by symptoms such as systemic inflammation...Read more
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β-Cyclodextrin Modified Graphene Oxide Bionanocomposite for pH-sensitive Release of Anti-cancer Drug
Nano-Biotech MedicalGraphene is a multifunctional carbon nanomaterial and could be utilized to develop platform technologies for cancer ther...Read more
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Finding a new approach for Treatment of osteoporosis with trace element and antioxidant in rat animal model
Metabolism and Metabolic DiseasesOne of the most common bone metabolic and endocrinal disorders is osteoporosis. It is defined by progressive bone loss, ...Read more
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Frequency of TET Resistance Gene and TEM Beta-Lactamase Resistance Genes in the Normal Flora of the Intestines of Addicted People Without symptoms of Intestinal Infection and Diarrhea, IRAN-Ahvaz City
Microbiology and Infectious DiseasesWide studies in National Institute for Drug Abuse(USA) are done with preventive goals, or risk and protective factors as...Read more
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evaluatin of expression of HIF-1alpha gene in various types of colon polyps
Medical GeneticsCancer in iran after cardiovascular diseases and accidents is the yhird leading cause of death. Research has shown that ...Read more
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Identification of Oral strains of Lactobacillus.species in patients with chronic periodontitis and healthy individuals
Microbiology and Infectious DiseasesOral infections constitute some of the most common and costly forms of infections in humans.Chronic periodontitis has be...Read more
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Frequency and Pattern of Resistance of AmpC-Beta-lactamase gene in Clinical isolates of Klebsiella pneumoniae from Zahedan Educational Hospitals
Microbiology and Infectious DiseasesThe detection of CTX-M-15 genes in ESBLs produced by Klebsiella pneumoniae strains provides useful information on epidem...Read more
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Influence of CYP2D6 and CYP3A4 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia and treatment response
Cancer; Prevention, Diagnosis and TreatmentXenobiotic- metabolizing enzymes compose an important line of defence against a variety of carcinogenes and environmenta...Read more
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Mortality effect of Silibinin on the A549 cell line
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the leading cause of cancer death in the world, with 1,375,000 deaths annually. Common chemotherapy such ...Read more
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The Relationship Between Renin- Angiotensin System Genetic Variation and Autism in Iranian Children; A Case –Control Study
Medical GeneticsAutism is a disease of complex nature with a significant genetic component.The importance of Renin-Angiotensin System(RA...Read more
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Investigation of antioxidant capacity of silver nanoparticles with Laurencia caspica seaweed on liver cancer cell line (HepG2)
Nano-Biotech MedicalHepatocellular carcinoma is a type of hepatocellular carcinoma that occurs most often in cases of hepatitis B and C, or ...Read more
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Suppression of interfering predominant bacteria in purification of Myxobacteria
Microbiology and Infectious DiseasesMyxobacteria have recently gained attention due to the ability to produce numerous biological active metabolites. Applyi...Read more
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The giant lipoma pediculated in the falciform ligament: a case report
Cancer; Prevention, Diagnosis and TreatmentIntroduction: Lipoma is one of the benign and common tumors of the limbs and trunk that’s rarely occurs in the abdomin...Read more
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The effects of anticancer of 7-hydroxycoumarine on the colon cancer cell line (HT29) and the normal mouse fibroblast cells (L929)
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer it is a lethal and common cancer. due to the development of drug resistance to chemical drugs, the ne...Read more
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Antimicrobial susceptibility of Acinetobacter baumannii isolated from different clinical samples in hospitalized patients
Microbiology and Infectious DiseasesAcinetobacter baumannii is a gram negative bacteria, which is cause multidrug-resistant nosocomial infection. Control an...Read more
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Evaluation of the level of some of the Trace elements in the sprayer workers
Metabolism and Metabolic DiseasesPesticides and toxins have deleterious effects on human health and can affect the biochemical factors of the body. There...Read more
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Anticancer Application of Camel Milk: A Review of Recent Research
Cancer; Prevention, Diagnosis and TreatmentBecause of importance of cancer and the side effects of existing therapies, it is essential to find new therapeutic stra...Read more
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Antimicrobial effects of new designed 2-amino-tetrahydro-4H-chromene-3-carbonithril derivatives against some pathogenic microbial strains
Microbiology and Infectious DiseasesChromenes are natural compounds which also called benzopyrane derivatives and chromene-4-one and had several biological ...Read more
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Comparison of Antibacterial Activity of Essential Oil of Varieties of Calendula Plant from Varamin (Iran) on Escherichia coli and Staphylococcus aureus
Microbiology and Infectious DiseasesUncontrolled use of conventional antibiotics and synthetic antibacterial medicine has led to the proliferation of microb...Read more
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Has Clusterin gene a role in spermatogenesis?
Women and Reproductive HealthAzoospermia is a male disorder observed in 1% of the general population and in 10–15% of infertile men that is defined...Read more
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Braest cancer micrometastatic detection in sentinele lymph nodes using molecular marker
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is prevalent malignancy among women in worldwide (1). Molecular diagnosis is recently proposed as a sensit...Read more
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Targeted killer gene therapy of breast cancer cells using Pseudomonas exotoxin A
Cancer; Prevention, Diagnosis and TreatmentTargeted expression of killer genes in tumor cells ensures specific elimination of cancer cells with minimal effect on n...Read more
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Effect of marjoram extract on sperm concentration and its survival percentage in oxidative-cadmium stress in adult male rats
Nutrition and HealthNutrition Safety and Health is one of the important factors in fertility.Cadmium as an environmental pollutant by free r...Read more
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Benefical Effects of hydroalcoholic extract of fenugreek seeds on some Biochemical factors and oxidative stress in high-fructose diet-induced metabolic syndrome in rats
Metabolism and Metabolic DiseasesBackground: Fenugreek (Trigonella foenum graecum) is a traditional herbal plant. seeds of Fenugreek have several propert...Read more
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BRCC2 gene inhibits lung cancer cell proliferation and invasiveness in vitro and in vivo:Prospect for gene therapy
Cancer; Prevention, Diagnosis and TreatmentLung cancer is one of the major causes of cancer related death worldwide .Despite recent improvements, resistance to con...Read more
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Fabrication and optimization of polymeric PAA nanoparticles loaded with the natural antibacterial component, curcumin.
Nano-Biotech MedicalCurcumin is a natural polyphenol molecule derived from the Curcuma longa plant which exhibits anticancer, antioxidant, a...Read more
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Design and expression of an immunogenic construct based on calcium sensing receptor antigen
Cancer; Prevention, Diagnosis and TreatmentDue to texture and small size, identifying the parathyroid from thyroid glands is a very difficult procedure. They shoul...Read more
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Structural Study of Horseradish Peroxidase upon Interaction with Gold Nanoparticles
Nano-Biotech MedicalRemarkable advancements have been made in the field of nanotechnology, including design of hybrid systems of nanoparticl...Read more
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Investigating the absorption of anti-cancer drugs on the surface of the boron nitride nano cage by the dense function theory
Nano-Biotech Medicalmagesterol is a drug used in the treatment of breast and endometrial cancer. Due to the unwanted side effects of this dr...Read more
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Qualitative and quantitative evaluation of airborne microorganisms and the concentrations of particulate and respirable matter causing from dust storm in the air of Ilam city: cross sectional study
Microbiology and Infectious DiseasesIntroduction: In recent years, dust storms frequently arrived to have large areas of the western half of Iran. Dust part...Read more
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3D Graphene Framework: A High-Performance Adsorbent for Antibiotics
Nutrition and HealthAntibiotics have been considered as emerging pollutants due to their continuous input and persistence in the aquatic eco...Read more
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ELISA Cross-Reactivity method to confirm recombinant fliC from salmonella typhimurium and evaluate impurities in purified recombinant protein
Microbiology and Infectious DiseasesRecombinant proteins as important materials for biomedicinal research, need high level of purity in order to be used in ...Read more