Majid Mahdavi
University of TabrizTabriz, Iran
Abstracts, [Author]
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Role of MicroRNAs in Multiple Sclerosis
Medical GeneticsMultiple sclerosis (MS) is an autoimmune neurodegenerative disease in which the body’s natural defense system attacks ...Read more
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TYCSB culture media reliability for S. mutans isolation
Microbiology and Infectious DiseasesAlthough the clinical significance of dental caries is well recognized, the exact etiology of the condition is not under...Read more
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Interaction of an anti-cancer drug Crizotinib with serum albumin: A docking study
Cancer; Prevention, Diagnosis and TreatmentCancer treatment is one of the major challenges of medical science today. Among them, lung cancer is a common type of ca...Read more
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The study of Apolipoprotein E4 allele distribution in parents of Down's syndrome children as a risk factor in Iran
Medical GeneticsDown syndrome(DS) is the most common chromosomal abnormality.The most important factor in DS is increased maternal age s...Read more
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Nephroprotective effect of Lavandula officinalis L. ethanolic extract in alloxan induced diabetic rats
Nutrition and HealthDiabetes mellitus (DM), a metabolic disorder is a major public health problem in both developed and developing countries...Read more
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Silencing of Mcl-1 and Bcl-2 by miR-15 Induces Apoptosis and Increases the Chemosensitivity of the CLL Cells
Cancer; Prevention, Diagnosis and TreatmentDespite advances in cancer therapy, drug resistance is a major problem in leukemia. Overexpression of anti-apoptotic pro...Read more
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EXPRESSION OF AN ANTIBODY FRAGMENT (SCFV) AGAINST AMYLOID-BETA USING T7 PROMOTER IN FED-BATCH CULTIVATION MODE
Microbiology and Infectious DiseasesIn the current investigation, the expression yield and solubility of Aβ antibody was analyzed using T7 promoter in fed-...Read more
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Effect of Extract of Origanum Vulgare on the activity of alanine aminotransferase enzyme in healthy and diabetic mice
Metabolism and Metabolic DiseasesWild Thyme is a great medicinal plant that grows in different areas of the Mediterranean and some parts of Asia.Present ...Read more
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Molcular Detection of Mupirocin Resistance in Staphylococcus aureus
Microbiology and Infectious DiseasesStaphylococcus aureus has become the most common cause of hospital acquired infections over the last few decades. The ba...Read more
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Apoptotic effect of anticancer drug Alimta on A549 calls is independent of HMGB1 release
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the leading cause of cancer-related deaths worldwide. Alimta is a new-generation antifolate drug, approv...Read more
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The Effect of Vitamin D on Diabetes Mellitus: A Systematic Review
Metabolism and Metabolic Diseases: Diabetes Mellitus is a common metabolic and non-infectious disorder that affects around 346 million people worldwide w...Read more
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Interference of Dopamine D2 Receptors and Food Restriction on Changing Anxiety Behavior and Serum Biochemical Factors in Adult Male Rats
Nutrition and HealthBackground: Food restriction (FR) and dopaminergic system affect on anxiety behavior, but it has not been determined the...Read more
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THE TOLE OF PROBIOTICS IN PUBLIC HEALTH
Nutrition and HealthIn the last decade, we have seen dramatic changes in understanding the role of foods in improving human health. scientif...Read more
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Investigating the role of exon7 axin2 in colorectal cancer (Laboratory and bioinformatics studies)
Cancer; Prevention, Diagnosis and TreatmentIn Iran, colon cancer is the third most common cancer. WNT pathway changes are commonly reported in this cancer. Among t...Read more
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Streptococcus mutans detection in Dental Plaque and saliva Samples
Microbiology and Infectious DiseasesDental caries is one of the most common prevailing disease in humans and a significant public health problem worldwide. ...Read more
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Treatment of vitamin D deficiency in pregnancy
Women and Reproductive HealthThe purpose of this study is the importance of Vitamin D in pregnancy and its treatment. Serum levels of Vitamin D in th...Read more
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Evaluation of antioxidant activity and cytotoxicity of an ethanol extract of leaves and fruits of Mespilus germanica on human lung cancer A549 cell line
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the most common cancers and natural products extracted from medicinal plants can play an important role i...Read more
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Determination Of intestinal Escherichia coli Pathotypes Frequency in Tehran Province By PCR
Microbiology and Infectious DiseasesEscherichia coli (E.coli) is an important member of the normal intestinal microflora for mammals, including humans.Diarr...Read more
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Association of umbilical coiling index with hypothyroidism and gestational diabetes mellitus.
Metabolism and Metabolic DiseasesGestational diabetes mellitus [GDM] and hypothyroidism are prevalent and potentially serious condition which may put mot...Read more
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Antioxidants as DNA protective compounds
Nutrition and HealthBased on the recent findings, antioxidants are some essential factors that can have major role on the health. The human...Read more
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Easy and efficient purification of flagellin from salmonella typhimurium ATCC 14028 without necessity of ultracentrifugation
Microbiology and Infectious DiseasesGram negative bacteria's Flagellin has many applications in diagnosis, treatment and vaccines. fliC, the major protein o...Read more
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Serum level of Dipeptidyl peptidase-4 as a potential biomarker for medullary thyroid cancer
Cancer; Prevention, Diagnosis and TreatmentAdipokines are the proteins secreted from adipose tissue which play an important role in the control of metabolism. Dipe...Read more
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The latest developments in pharmaceutical biotechnology
Nano-Biotech MedicalBackground and Aim: Biotechnology has produced over 200 types of drugs and new vaccines that include products for the tr...Read more
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the effect of Lactobacillus acidophilus (La) and Lactobacillus rhamnosus (Lr) on proliferation and invasion of Colorectal cancer cells (Caco2).
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer is one of the most common epithelial cancers in the world. Many studies have been conducted on the inh...Read more
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Crocin suppresses multidrug resistance in MRP overexpressing ovarian cancer cell line
Cancer; Prevention, Diagnosis and TreatmentCrocin, one of the main constituents of saffron extract, has numerous biological effects such as anti-cancer effects. M...Read more
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Effects of Rosmarinic acid on oxidative stress and total antioxidant capacity in vivo study
Metabolism and Metabolic DiseasesDiabetic disease is characterized by chronic hyperglycaemia. Numerous studies have shown that in diabetes mellitus, ther...Read more
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Hydroxyapatite-Gelatin-bone marrow stromal cells construct as an excellent bone graft in animal model
Stem cell and Medical ApplicationsBone healing of critical-sized defects are one of the most challenging orthopaedic problems. In the current study, the e...Read more
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The Relationship between STR-PCR Chimerism Analysis and Chronic GvHD Following Hematopoietic Stem Cell Transplantation
Cancer; Prevention, Diagnosis and TreatmentGraft-versus-host disease (GvHD) is one of the serious complications of HSCT. Its prevalence has been reported as 20-50 ...Read more
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Frequency of TET Resistance Gene and TEM Beta-Lactamase Resistance Genes in the Normal Flora of the Intestines of Addicted People Without symptoms of Intestinal Infection and Diarrhea, IRAN-Ahvaz City
Microbiology and Infectious DiseasesWide studies in National Institute for Drug Abuse(USA) are done with preventive goals, or risk and protective factors as...Read more
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A foundation for universal T-cell based adoptive immunotherapy
Cancer; Prevention, Diagnosis and TreatmentThe patient-specific autologous therapy could be a significant limiting factor in the large-scale exploitation of CAR te...Read more
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Studying the relation of blood lead level with the thyroid hormones and blood factors
Metabolism and Metabolic DiseasesLead has many applications in the industry but does not play a specific physiological role in the body. According to per...Read more
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MUC21 as a suitable candidate for immunotoxins development for targeting esophageal cancer
Cancer; Prevention, Diagnosis and TreatmentEsophageal cancer is the world's eighth most common cancer and the sixth most common cause of cancer death in the world....Read more
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Investigation of A New Paclitaxel Nano Niosomal formulation and Biological Evaluation of Entrapped Paclitaxel on breast cancer cell line
Nano-Biotech MedicalRegarding that the breast adenocarcinoma is the most widespread disease among women, paclitaxel, an anti-cancer drug, co...Read more
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Ginseng For Improving The Quality Of Life In People With Cancer and Fatigue- A Systematic Review
Cancer; Prevention, Diagnosis and TreatmentBackground and purpose: An important issue in cancer health care is the improvement in quality of life (QoL). Physicians...Read more
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Evaluation of the effect of saturated and unsaturated fatty acids on the growth and production of outer membrane vesicles in human gut microbiota
Microbiology and Infectious DiseasesA diverse and complex symbiotic microbial community colonize in human host,espicially in the gastrointestinal tract,refe...Read more
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Preconditioning of bone marrow-derived mesenchymal stem cells by AdipoRon potentiates cell migration ability, in vitro.
Stem cell and Medical ApplicationsMesenchymal stem cells (MSCs) have represented a great potential in recent stem cell-based therapies as well as regenera...Read more
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Perineal massage during pregnancy and perineal safety during childbirth
Women and Reproductive HealthIntroduction: Women frequently suffer from perineal trauma during childbirth, especially during the first childbirth. ...Read more
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LPS Effects on induction of regulatory T cells in peripheral blood mononuclear cells in endometriosis patients
Women and Reproductive HealthEndometriosis is an estrogen-dependent chronic inflammatory disease affecting women in reproductive ages. Regulatory T c...Read more
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Medicinal plants in the treatment of infertility
Women and Reproductive HealthInfertility is disability of a couple to reach pregnancy for more than one year despite regular sexual intercourse. The ...Read more
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Evaluation and comparison of digestion in two traditional and contemporary medicine schools And its effect on the treatment of diseases
Nutrition and HealthProper nutrition is one of the principles of "preserving health" in traditional and contemporary medicine. Wha...Read more
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The effect of diet in preventing of colorectal cancer: A systematic Review
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer (CRC) is the third most commonly diagnosed cancer in worldwide and it is established that diet has an ...Read more
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The efficacy of Leptin on physical and psychological stress causing gastric ulcer: Participations of nitric oxide and prostaglandin E2
Nutrition and HealthThe present study aimed to assess the effects of Leptin on physical and psychological stresses inducing gastric ulcer. T...Read more
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Silibinin Inhibits miR-17 in Co-cultured HUVECs with A549 Cell Line
Cancer; Prevention, Diagnosis and TreatmentMicroRNAs are involved in different biological processes including cell proliferation and apoptosis, the two intimately ...Read more
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The role of oils in breast cancer in women (systematic review)
Cancer; Prevention, Diagnosis and TreatmentAbout one-third of cancers may be related to diet, along with lifestyle and physical activity. International data show t...Read more
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The Relationship Between Renin- Angiotensin System Genetic Variation and Autism in Iranian Children; A Case –Control Study
Medical GeneticsAutism is a disease of complex nature with a significant genetic component.The importance of Renin-Angiotensin System(RA...Read more
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Molecular mechanism of alpha-2 adrenergic receptors in locus Coeruleus
Medical GeneticsPain is one of the most common forms of psychological stress and the most common phenomenon in medical science. Analgesi...Read more
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Effect of Hypiran on the oxidative stress responses in experimental autoimmune encephalomyelitis
Nutrition and HealthExperimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis. The hallmark of this disease i...Read more
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Evaluation of Acholeplasma laidlawii in biologic products by PCR method
Microbiology and Infectious DiseasesContamination of biological products and cell cultures is one of the important problems in producing a good and safe pro...Read more
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Comparison of antimicrobial activity of hydroalcoholic extract of fig(Ficus carica) against Staphylococcus aureus(MSSA & MRSA) with some antibacterial drugs
Microbiology and Infectious DiseasesStaphylococcus aureus is one of the five most common causes of hospital infections and death the worldwide. The excessiv...Read more
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Cloning, expression and functional assay of bacterial Uricase, a medical enzyme for the treatment of chronic gout
Metabolism and Metabolic DiseasesUricase, which is originated from a variety of organisms including bacteria, is an important agent for tracing of Uric A...Read more
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Study of HER2 gene expression in AGS cell line after treatment of cells with Crocus sativus (Iranian Saffron) extract
Cancer; Prevention, Diagnosis and TreatmentThe study of HER-2 gene in cancers, especially gastric cancer, is of great importance. This gene, has been shown to inc...Read more
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Anthropometric Survey of Worker Population in Bandar-Abbas
Cancer; Prevention, Diagnosis and Treatment1. Background Anthropometry is the science of measurement of body characteristics such as reach, body segment length, ...Read more
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the relationship between general and abdominal obesity and advanced glycation end products
Nutrition and HealthAdvanced glycation end products (AGEs) are a heterogeneous group of macromolecules that are formed by the non-enzymatic ...Read more
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Frequency of TEM and SHV genes in the strains of Acinetobacter producing broad-spectrum isolated ß-lactamases from Zahedan patients by PCR method
Microbiology and Infectious DiseasesAcinetobacter baumannii is one of the most important factors in hospital infections, and its Colonization rate in hospit...Read more
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Prevalence of Pediculus capitis among School Children in the Eastern Area of Ahvaz, Southwestern Iran
Microbiology and Infectious DiseasesHead lice are wingless, obligate ectoparasites of humans, which affect millions of children worldwide, especially those...Read more
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The role of nutrition in gestational diabetes
Women and Reproductive HealthGestational diabetes is a condition in which blood glucose levels are rising during pregnancy and diabetes symptoms in a...Read more
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Correlation between oral health status and salivary total antioxidant capacity in type 2 diabetes mellitus among Iranian adults
Metabolism and Metabolic DiseasesDiabetes mellitus is a chronic metabolic disease leading to several complications. Among these, dental caries are consid...Read more
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A simple way for extracting singular porphyrin peaks from total fluorescence spectrum of plasma
Metabolism and Metabolic DiseasesPorphyrins are organic compounds formed from the breakdown of hemoglobin. Any disturbance in porphyrins’ level can be ...Read more
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Alterations of gyrA in Enterobacteriaceae isolated of urinary tract infection resistance to quinolones antibiotics
Microbiology and Infectious DiseasesUrinary tract infection is one of the most common infections, which if not treated, it can be cause seriouse problem in ...Read more
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Investigating th expression of E-cadherin gen among patients suffering from stomach cancer in West Azerbaijan province
Medical GeneticsGastritis Cancer is one of the general death causes of cancer all over the world. According to the results of the resea...Read more
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The effect of celastrol on gene expression of TNF-α (Tumor necrosis factor-a) induced by Influenza A virus (PR8/H1N1) in MDCK cells
Microbiology and Infectious DiseasesInfluenza A virus (IAV) can cause acute respiratory distress syndrome, which leading to kill 250000 to 500000 of world ...Read more
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An update review about stem cell therapy for diabetes mellitus
Stem cell and Medical ApplicationsMesenchymal stem cells (MSCs) are the most widely used stem cells of the human body because of successful isolation, and...Read more
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Drafting maggot therapy in personalized cancer therapy
Cancer; Prevention, Diagnosis and TreatmentIn some personalized cancer therapies the elimination of the tumor will be a result of the injection of flesh- eating ba...Read more
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HETEROGENEITY OF ESCHERICHIA COLI ISOLATES WITHIN DIFFERENT
Microbiology and Infectious DiseasesAim:Escherichia coli is one of the most important bacterial pathogens causing urinary tract infections (UTIs) . This bac...Read more
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Association between the CYP2E1 polymorphisms and CML risk in Iranian population
Medical GeneticsPolymorphism in the genes encoding detoxification enzymes results in variability to metabolize carcinogens and cause int...Read more
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Optimization of the best concentration of Aloe vera extract for treating gastric cancer cells in order to reduce HER-2 gene expression
Cancer; Prevention, Diagnosis and TreatmentHER2 is a glycoprotein that has tyrosine kinase activity and plays an important role in guiding growth signals. Its expr...Read more
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Purification of poly ribosylribotil phosphate capsule from Heamophilus influenza type- b strain ATF2 cultivated in bioreactor
Microbiology and Infectious DiseasesHaemophilus influenzae is a small gram negative cocobacilli non motile and can be seen as pleomorphic. H.inf.can cause ...Read more
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Evaluation of NTT and Double-Test in screening of Down Syndrome
Women and Reproductive HealthPrenatal diagnosis of genetic, congenital and hereditary diseases is the first step to prevent and control these prob...Read more
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Dietary intake of antioxidants in elderly: A case-control study in Iran
Nutrition and HealthNutrient deficiencies such as antioxidants are common problems in elderly subjects which can result in different cancers...Read more
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In silico design and analysis of crRNA for post transcriptional regulation of oncogenic miR-128-2 and miR-217 by CRISPR-C2C2 technique.
Medical GeneticsBased on recent studies some microRNAs could have drug resistant effects in turmeric cells during therapy. There are evi...Read more
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Molecular monitoring of Chronic Myeloid Leukemia in Chronic Phase (CML-CP)
Medical GeneticsQuantification of the BCR-ABL transcript is recommended to follow-up CML patients that treated by Imatinib mesylate (IM)...Read more
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Green synthesis of Silver nanoparticles by Alhagi camelorum gum
Nano-Biotech MedicalSilver nano particles (AgNPs) are used in textiles, cosmetics, tooth brushes, home appliances, food packages and many ot...Read more
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Application of stem cells in modern therapeutic methods
Stem cell and Medical ApplicationsStem cells are one of the modern therapies being used over recent years to treat diseases such as repairing damaged hear...Read more
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Identification of Oral strains of Lactobacillus.species in patients with chronic periodontitis and healthy individuals
Microbiology and Infectious DiseasesOral infections constitute some of the most common and costly forms of infections in humans.Chronic periodontitis has be...Read more
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Effect of folic acid supplementation on acute effects of trimethoprim/sulfamethoxazole on histopathological changes in the testes of adult male rats
Stem cell and Medical ApplicationsMale infertility has been reported following long-term sulfasalazine use for ulcerative colitis treatment. However, the ...Read more
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Frequency of Binding Site at C-Terminal of Helicobacter Pylori CagA Separated from Gastric Tissue Biopsy of Patients with Gastroduodenal Disorders in Shafa Hospital in Khorramabad
Microbiology and Infectious DiseasesHelicobacter pylori (H. pylori) is a gram-negative, microaerophilic bacterium in gastric mucosa. It has a helical shape...Read more
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Design, synthesis and application of conjugated gold nanoparticles in photodynamic therapy
Nano-Biotech MedicalPhotodynamic therapy (PDT) has been developed as a novel method for cancer therapy. PDT involves the combined use of a p...Read more
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Impact of CYP3A5 and CYP3A4 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia and treatment response
Medical GeneticsCYP3A5 and CYP3A4 are the members of the CYP3A gene family which metabolizes 50% of therapeutic drugs and steroid hormon...Read more
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Association between Biochemical Markers BHCG in Screening First Trimester of Pregnancy in Women with PCOS
Women and Reproductive HealthPCOS (polycystic ovary syndrome) is a common endocrine system disease among women of reproductive age. Its prevalence in...Read more
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Microencapsulation and double-coating of probiotic bacteria for enhancement of their viability and targeted delivery
Nutrition and HealthThe purpose of this study was to assess the protecting character of double coated beads of alginate-chitosan-Eudragit S1...Read more
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Detection of Borrelia microti in blood samples spotted on DNA Banking Card by using Loop-Mediated Isothermal Amplification (LAMP)
Medical GeneticsTick-borne relapsing fever (TBRF) is an endemic disease in Iran, with more 100 annual cases. The glycerophosphodiester ...Read more
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Effect of EMF on Semen TBARS Concentration
Women and Reproductive HealthElectrical instruments in human life by development of applications causes new biological phenomenon in this century. Ne...Read more
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Evaluation and comparison of digestion in two traditional and contemporary medicine schools And its effect on the treatment of diseases
Nutrition and HealthIn traditional medicine, one of the three most important nutritional principles is digestion. In our digestion, we deal ...Read more
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Investigating the role of Nanodrugs in the treatment of Candida and Aspergillus infectons
Microbiology and Infectious DiseasesInvasive fungal infections are a major problem for immunocompromised patients in intensive care units. Morbidity and m...Read more
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Development of an Antagonistic TGF-β by Directed Blocking of its TβRI Binding Site to Inhibition TGF-β Signaling
Cancer; Prevention, Diagnosis and TreatmentTransforming growth factors beta (TGF-βs) play vital roles in regulating cell growth, differentiation and inflammation....Read more
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Identification and Cloning of Plasposon Insertion Site in Four Mutants of Pseudomonas Gingeri Deficient in White Line Reaction
Microbiology and Infectious DiseasesAntibiotic resistance is an important concern in the world and also in Iran. Identifying new antimicrobial strategies to...Read more
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Client's Attitude Towards legal and Ethical Aspects of Sperm Donation in a Health Center of Tehran
Women and Reproductive HealthSperm donation is one of the technologies associated with infertility treatment. Some couples don't have any child due t...Read more
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Anti-anxiety effects of sinapic acid in NMRI mice
Nutrition and HealthThe present study investigated the anxiolytic effects of sinapic acid on NMRI mice behavior in the elevated plus-maze (E...Read more
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An investigation on the structure and function of the cell surface breast-specific antigens for development a new generation of immunotoxins
Cancer; Prevention, Diagnosis and TreatmentBreast cancer with heterogeneous features in morphology, clinic, and responses to therapeutic options, is one of the mos...Read more
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Anticancer Application of Camel Milk: A Review of Recent Research
Cancer; Prevention, Diagnosis and TreatmentBecause of importance of cancer and the side effects of existing therapies, it is essential to find new therapeutic stra...Read more
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Intelligent Stimuli Responsive Core@Sell Nanobiomaterial: Biomedical Opportunities and Challenges
Nano-Biotech MedicalNanoscale objects are powerful devices in biotechnology medicine and biomedical sciences. They are potential applicants ...Read more
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Optimization of epi-drug combination against Glioblastoma multiform cell line (U251) using Response Surface Methodology
Cancer; Prevention, Diagnosis and TreatmentGlioblastoma multiform (GBM) is the most common and aggressive form of primary brain cancer and has a dismal prognosis, ...Read more
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study of mesenchymal stem cell differentiation to chondrocyte on electrospun nanofibrous polyvinyl alcohol alginate sulfat blend
Stem cell and Medical ApplicationsCartilage tissue engineering is used as a potential solution for replacing or repairing damaged tissue. In this method, ...Read more
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Biosynthesis of Gold nanoparticles by Areca palm fruit extract
Nano-Biotech MedicalTargeted drug delivery by Gold nano particles (AuNPs) is a new era in pharmaceutical research; i.e. curing tumoral cance...Read more
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Investigation the effect of low intensity pulsed ultrasound (LIPUS) on proliferation of G 292 osteosarcoma cells on 3D porous PLGA/β-TCP scaffold within perfusion bioreactor
Stem cell and Medical ApplicationsInvestigation the effect of low intensity pulsed ultrasound (LIPUS) on proliferation of G 292 osteosarcoma cells on 3D p...Read more
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Prevalence of gastric cancer in the patients undergoing bariatric surgery
Cancer; Prevention, Diagnosis and TreatmentIntroduction and goal: The number of obese people has grown up to 1.9 billion worldwide, that a large number of complica...Read more
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Finding a new approach for Treatment of osteoporosis with trace element and antioxidant in rat animal model
Metabolism and Metabolic DiseasesOne of the most common bone metabolic and endocrinal disorders is osteoporosis. It is defined by progressive bone loss, ...Read more
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Autism spectrum disorder (ASD) and cancer: both share same genes but different outcomes.
Medical GeneticsAutism spectrum disorder (ASD) is a neurodevelopmental disorder and it is characterized by social and communication prob...Read more
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Investigating the effects of saffron and melatonin with radiotherapy on viability of Hela cells
Cancer; Prevention, Diagnosis and TreatmentCancer is one of the biggest threats to human life. None of cancer treatment have not succeeded completely. One of the n...Read more
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Non-muscle Myosin Heavy Chain 9 Gene (MYH9) Polymorphism (rs4821481) is Associated with Urinary Albumin Excretion in Iranian Diabetic Patients
Medical GeneticsMyosin heavy chain 9 (MYH9) gene polymorphisms have been implicated in a different type of renal disease as well as neph...Read more
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The effect of curcumin, zinc and N-acetylcysteine on the MMP9 expression
Metabolism and Metabolic DiseasesCardiovascular diseases (CVD) are mostly prevalent in the general population.Matrix metalloprotease 9 (MMP9) is a matrix...Read more
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Familial occurrence of Mayer-Rokitansky-Küster-Hauser syndrome in two siblings in Iran
Medical GeneticsFamilial occurrence of Mayer-Rokitansky-Küster-Hauser syndrome in two siblings in Iran Asadi fatemeh 1*, shokouholsa...Read more
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Investigation of Lead and Chromium Elements in Female Patients with Breast Cancer Before and After Chemotherapy
Cancer; Prevention, Diagnosis and TreatmentHeavy metals such as lead and chromium can be in various forms, including free ions, metal compounds or carcinogenic par...Read more
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The Evaluation of Methicillin Resistant Staphylococcus aureus (MRSA) Colonization on Skin Lesions in Patients with Psoriasis
Microbiology and Infectious DiseasesPsoriasis is a chronic and inflammatory disease of the skin. Recently, the role of microbial agents in the development o...Read more
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Recent study about Genetics of Human Obesity
Medical GeneticsObesity has become a global epidemic and contributes to the increasing burden of type 2 diabetes, cardiovascular disease...Read more
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case report of Albinism with pseudo dominant inheritance
Medical GeneticsOculocutaneous albinism type 1 is characterized by hypopigmentation of the skin and hair and the distinctive ocular chan...Read more
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Using micronuclei assay in cancer treatment
Medical GeneticsCancer is one of the leading causes of illness and mortality worldwide, after cardiovascular disease. There are differen...Read more
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Knowledge and Practice of Breast Self-Examination Among Female Students in Sari Islamic Azad University in 2015-2016
Cancer; Prevention, Diagnosis and TreatmentBreast self-examination (BSE) is one of the ways of prevention and early detection of breast cancer. The aim of this stu...Read more
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Preparation and assessment of chitosan-polyethylenimine-carboxymethyl dextran nanoparticles for efficient siRNA delivery in vitro
Nano-Biotech MedicalAmong polycation nanoparticles, chitosan nanoparticles (Ch) have emerged as promising carriers for gene delivery, nevert...Read more
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Evaluation of cardiac differentiation potential of menstrual blood- derived stem cells seeded in biocompatible Bombyx mori silk fibroin scaffold in co-culturing with neonatal rat Cardiomyocytes
Stem cell and Medical ApplicationsCardiovascular disorders are leading cause of million deaths each year which reveals the significance of current limitat...Read more
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Evaluation of cytotoxicity effects and NM23 gene expression against breast cancer T47D cells treated by Zn oxide nanoparticles( ZnNPs)
Stem cell and Medical ApplicationsBreast cancer is the second leading cause of cancer related death worldwide among women. Many investigations have confir...Read more
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Cloning and expression of recombinant Cecropin A in Nicotiana tabacum L. hairy roots and its antimicrobial properties
Microbiology and Infectious DiseasesCecropins are a group of antimicrobial peptides (AMP) derived from innate immune system of various multicellular organis...Read more
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Study of DNA methylation pattern in sf-1 gene promoter region in endometriosis tissue samples of women in north west of Iran
Medical GeneticsEndometriosis is an estrogen-dependent inflammatory disease. Its defining feature is the presence of endometrium-like ti...Read more
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Reproductive Health Training Program on Students in IRAN: An Action Research Approach
Women and Reproductive HealthTransition from adolescence to adulthood is one of the important periods in the individual life. New behaviors are learn...Read more
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Qualitative and quantitative evaluation of airborne microorganisms and the concentrations of particulate and respirable matter causing from dust storm in the air of Ilam city: cross sectional study
Microbiology and Infectious DiseasesIntroduction: In recent years, dust storms frequently arrived to have large areas of the western half of Iran. Dust part...Read more
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Study of matrix metallo proteinase (MMP)-9 gene & its phylogeny tree as a critical gene in metastases
Medical GeneticsThere has been a clear connection between MMPs,ECM degradation & cancer cell invasion. Matrix metalloproteinase(MMP)-9, ...Read more
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Lipase adsorbtion on the single layer geraphene oxide dependes on pH and temperature
Nano-Biotech Medicalgraphene oxide (GO) has been used as a matrix for lipase immobilization. GO chemical properties are reported beneficial ...Read more
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Combination of ultrasonic waves and dynamic shear stress by design of a novel perfusion bioreactor for 3D bone tissue engineering
Stem cell and Medical ApplicationsIt is shown that mechanical loading by ultrasound enhanced cell proliferation and differentiation. The aim of present st...Read more
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Altered miR-335-5p and miR-124-3p expression in gastric cancer
Medical GeneticsGastric cancer (GC) is fourth most common cancer and third leading cause of cancer mortality worldwide. Considerable eff...Read more
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The relationship between TPH1 (rs1800532) and TPH2 (rs4570625) polymorphisms in type 1 bipolar patients compared with healthy subjects
Medical GeneticsBipolar disorder has episodes of depression and mania or hypomonia. several serotonin-associated genes correlated with S...Read more
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Distribution of Main Variants in Reactions of Cytotoxin vacA of H. pylori in Gastric Biopsy Specimens
Microbiology and Infectious DiseasesHumans have suffered digestive problems for centuries, and we now know that H. pylori are one of their most important ca...Read more
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Comparative study of Calendula officinalis and Matricaria chamomilla extracts on Cisplatin induced neuropathic pain
Cancer; Prevention, Diagnosis and TreatmentCisplatin is one the most important cancer chemotherapy agents that uses for two decades. Neuropathic pain induced by th...Read more
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Evaluation of Adenovirus in Pseudomonas aeruginosa susceptible keratitis by PCR molecular method
Microbiology and Infectious DiseasesKeratitis is inflammation of the cornea of the eye. In keratitis, microbial agents are important. In the presence of inf...Read more
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Fertilization rate would be improved after vitrification of immature mouse oocytes
Women and Reproductive HealthVitrification of oocyte is a promising technique to preserve fertility in different species, but it has deleterious effe...Read more
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Inflammatory markers, vitamin D status and FokI polymorphism of the VDR gene in overweight women
Nutrition and HealthThe present study aimed to evaluate the relationship between inflammatory markers, vitamin D status and FokI polymorphis...Read more
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Effect of Zinc Oxide Nanoparticles on expression of proapoptotic BAX and Bcl-2 in Testicular Tissue of NMRI Adult Mice
Nano-Biotech MedicalZinc oxide nanoparticles have numerous applications in medicine and industry. These materials are delivered to the tissu...Read more
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The effects of minoxidil on gene expression in the bulb and bulge region of hair follicles by Real time-PCR
BeautyMinoxidil is the most common drug used for treatment androgenic alopecia.Studies have shown that this drug can increase ...Read more
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Antiangiogenic Effect of Endostatin-derived Peptides on a Mouse Model of Colon Cancer
Cancer; Prevention, Diagnosis and TreatmentColon Cancer is among the most common malignancies worldwide. Angiogenesis is the formation of new microvasculature thro...Read more
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Effect of Staphylococcus aureus isolates in food samples on hep2 cell line
Microbiology and Infectious DiseasesStaphylococcus aureus produces a range of protein-rich toxins and also extracellular pathogens that contribute to bacter...Read more
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β-Cyclodextrin Modified Graphene Oxide Bionanocomposite for pH-sensitive Release of Anti-cancer Drug
Nano-Biotech MedicalGraphene is a multifunctional carbon nanomaterial and could be utilized to develop platform technologies for cancer ther...Read more
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Comparison of miR-605 expression in normal and tumor tissue samples of patients with colorectal cancer.
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer (CRC) is the third common type of cancer, and is considered as the main cause of cancer deaths in both...Read more
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Astaxanthin decreases cell viability in MDA-MB-231, but not in non-tumorigenic human breast cell line MCF 10A
Cancer; Prevention, Diagnosis and TreatmentConsidering the high prevalence of breast cancer in Iran, its rising incidence, and the high mortality rate of patients ...Read more
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Identification of bacterial agents of urinary tract infection in patients referred to a laboratory during six months
Microbiology and Infectious DiseasesEstablishing a diagnosis of symptomatic UTI requires a patient to have symptoms and signs of a UTI and laboratory tests ...Read more
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Assessment of Tuberculous arthritis using molecular technique
Microbiology and Infectious DiseasesBacterial arthritis is one of the arthritis diseases known that can rapidly cause joint damage. Among the bacteria caus...Read more
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Efficacy of Bone Marrow Mesenchymal Stem Cells and an Amniotic Membrane on the Number of Mast Cells and Degranulation in Random Skin Flaps in Rats
Stem cell and Medical ApplicationsSkin flap procedures are usually used in plastic surgery. Failing can follow, lead to the necrosis of the flap. Therefor...Read more
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The Expression Profile of ERBB3 and Its Ligand NRG1 on Depressed Patients Investigation in Hormozgan
Medical GeneticsMajor depressive disorder (MDD), also known simply as depression, is a mental disorder characterized can negatively affe...Read more
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TThe Biological Effects of Aqueous Extract of Ephedra major on the Development of Balb/C Mouse Embryos 7Th to 10Th Days of Pregnancy
Nutrition and HealthAqueous extract of Ephedra major used as a drug for blood pleasure, sleep disorder and lose weight. But it is effects on...Read more
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Mediterranean dietary pattern adherence modify the association between FTO genetic variations and obesity phenotypes
Nutrition and HealthThere is an increasing interest in examining whether dietary patterns modify the association of fat mass and obesity ass...Read more
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Investigating the Relationship between Polymorphism of p22phox in Smoker Population with Chronic Obstructive Pulmonary Disease (COPD) and Susceptibility to Disease
Medical GeneticsCOPD (chronic obstructive pulmonary disease) is a slowly progressive condition characterized by airflow limitation, whic...Read more
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Human reovirus destroys liver cancer cell line (Huh-7)
Cancer; Prevention, Diagnosis and TreatmentThe Huh-7 cell line was derived from a liver tumor in a 57-year-old Japanese male patient in 1982. Hepatocellular carcin...Read more
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Site Directed Mutagenesise of L-Asparagine as an Improveed Anti Cancer Protein with Increased L-ASNase Activity
Cancer; Prevention, Diagnosis and TreatmentL-Asparaginase (L-ASNase) is an FDA approved enzyme which is widely used in fight against acute lymphoblastic leukemia a...Read more
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BRCC2 gene inhibits lung cancer cell proliferation and invasiveness in vitro and in vivo:Prospect for gene therapy
Cancer; Prevention, Diagnosis and TreatmentLung cancer is one of the major causes of cancer related death worldwide .Despite recent improvements, resistance to con...Read more
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Study of gene expression network in varicose veins disease by microarray expression analysis
Medical GeneticsThere is a strong body of circumstantial evidence which implicates genetics in the etiology and pathology of and venous ...Read more
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The effects of methanolic soy extract on ovary tissue modification in model of polycystic ovary syndrome as an inflammation state
Women and Reproductive HealthIntroduction and Objective: Chronic low-grade subclinical inflammation has been increasingly recognized as an interposer...Read more
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Some candidate Biomaterials for Amniotic Membranes (AM) Regeneration: a review
Stem cell and Medical ApplicationsAmniotic Membranes (AM) wich form the amniotic sac filled by amniotic fluid and completely surrounds the embryo/fetus. I...Read more
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Benefical Effects of hydroalcoholic extract of fenugreek seeds on some Biochemical factors and oxidative stress in high-fructose diet-induced metabolic syndrome in rats
Metabolism and Metabolic DiseasesBackground: Fenugreek (Trigonella foenum graecum) is a traditional herbal plant. seeds of Fenugreek have several propert...Read more
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Antibacterial properties of saffron
Microbiology and Infectious DiseasesSaffron is a small herb of the Welsh family. This is a plant with spherical onions which surrounded by a brown membrane....Read more
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Evaluation of cytotoxicity, viability and induced oxidative stress by Nickel (II) complex of thiosemicarbazone
Cancer; Prevention, Diagnosis and TreatmentThiosemicarbazones and their metal complexes have significant biological activities including anticancer, antibacterial,...Read more
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An Evaluation of Tissue Destruction Time in Phrenic Nerve after Death and Counting the Number of Nerve Fibers in C3, C4 and C5 Branches
Cancer; Prevention, Diagnosis and Treatmentمقدمه اعصاب فرنیک چپ و راست، محرک اصلی عضلة دیافراگم میباشند( .)5ای...Read more
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Genotyping of Escherichia coli strains isolated from hospitals sewage
Microbiology and Infectious DiseasesToday one of the most common problems in the health society is the way of treating multidrug resistant (MDR) organisms. ...Read more
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Chrysin therapy could suppress breast cancer development
Cancer; Prevention, Diagnosis and TreatmentChrysin is a natural flavonoid found abundantly in honey, gum, and many plant extracts. It rep¬resents anti-cancer feat...Read more
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Design and expression of an immunogenic construct based on calcium sensing receptor antigen
Cancer; Prevention, Diagnosis and TreatmentDue to texture and small size, identifying the parathyroid from thyroid glands is a very difficult procedure. They shoul...Read more
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A Comparison of the efficacy of Fluconazole-loaded PLGA Nanospheres and Fluconazole on attachment of Candida albicans to hela cell
Microbiology and Infectious DiseasesThe human pathogenic fungus Candida albicans is commonly found on mucosal surfaces, such as the vagina. It has been wide...Read more
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Preparation and characterization of Nanofibers Using an Electrospinning Technique as ocular drug delivery
Nano-Biotech MedicalFor the treatment of anterior eye segment infections using anti-infective agents, topical ocular application is the most...Read more
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The effect of manual acupuncture on anthropometric parameters in obese and overweight patients
Nutrition and HealthObesity is a chronic disease which is on the increase. Treatments of obesity include diet therapy, exercise, behavior th...Read more
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Removal of Nickel (II) From Drinking Water Using Thiol-Functionalized Chitosan
Nano-Biotech MedicalSome heavy metals are the causes of various diseases among humans. Thus, removing heavy metals is necessary in order to ...Read more
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Electrospun PVA/PVP/chitosan Membrane with Controlled Release of Antibiotics for intraperiodontal pocket drug delivery
Nano-Biotech MedicalGingivitis and periodontitis have become major public health problem in the world. Such growing incidence of periodontit...Read more
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Determining the Interactions between Major Dietary Patterns and LRP5 Genotypes (rs556442) on Bone Discordance in Postmenopausal Women Referred to Shariati Hospital
Nutrition and HealthOne of the challenges in the diagnosis of osteoporosis is bone discordance. Many studies have confirmed an association ...Read more
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Nano ironoxide effects on mouse heart development; a genome wide mRNA level study
Nano-Biotech MedicalNanoparticles have been used for clinical applications such as Hyperthermia, increasing the resolution of magnetic reson...Read more
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Investigation of epigenetic effects of Disulfiram on the demethylation of RASSF1A gene promoter in breast cancer cell line MCF-7
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the most common type of cancer among women with very high mortality rates in the world. Genetic and epi...Read more
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Silencing of TIM-3 expression by miR-326 affects apoptosis and proliferation of human HL-60 leukemia cell line
Cancer; Prevention, Diagnosis and TreatmentLeukemia Stem Cells (LSCs) are the main reason for drug-resistance and disease relapse in Acute Myeloid Leukemia (AML). ...Read more
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Sensitivity of levofloxacin in combination with ampicillin-sulbactam and tigecycline against multidrug-resistant Acinetobacter baumannii
Microbiology and Infectious DiseasesDuring the last decades, emergence of antibiotic resistance among A. baumannii has been considered as a worldwide alarm....Read more
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Development and implementation of a novel panel consisting 16 STR markers linked to the HLA-gene-cluster applicable for HLA-typing, PND&PGD
Medical GeneticsPGD (Pre-implantation Genetic Diagnosis) in combination with human leukocyte antigen (HLA) matching, allow not only sele...Read more
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Comparative investingation of effects of the agricultural pesticides (diazinon and chlorpyrifos) on spermatogenesis in male BALB/c male mice
Nutrition and HealthDiazinon and chlorpyrifos are kind of organophosphate toxins used for agricultural pests. These toxins control acetylch...Read more
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Cancer Stem Cell Therapy Based on Nanostructure Drug Vehicle, PMBN-IL3-GA
Nano-Biotech MedicalTo overcome difficulty of cancer treatment by conventional chemotherapy methods, the targeting drug delivery based on Na...Read more
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Investigation of microRNAs involved in the EGFR molecular pathway as a biomarker in early detection of colorectal cancer
Medical GeneticsColorectal cancer (CRC) is one of the most common cancers in the world. The highest incidence of CRC in Europe, North Am...Read more
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The effect of ziziphora extract on the expression of the Claudin_1 gene in the AGS cell line
Cancer; Prevention, Diagnosis and TreatmentClaudins are the main structural and functional proteins of tight junctions in epithelial cells. The altered expression ...Read more
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Food Patterns and Framingham Risk Score in Iranian Adults: Tehran Lipid and Glucose Study: 2005-2011
Nutrition and HealthHealthy dietary habits can prevent cardiovascular diseases (CVD). The aim of the present study was to investigate the as...Read more
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Relationship of pre-body mass index with umbilical coiling index in gestational diabetes and non-gestational diabetes mellitus.
Metabolism and Metabolic DiseasesIt has been well documented that overweight or obesity before pregnancy is a strong predictor of gestational diabetes me...Read more
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The Study of the Frequency of Antibiotic Usage as an Important Factor in Appearing Antibiotic Resistance in All of the Units in Namazi Hospital
Microbiology and Infectious DiseasesAs the unusual increase in using antibiotics has been suggested as an indicative factor in appearing antibiotic resistan...Read more
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Investigation of mutations and polymorphisms in exon 11, 12, 22 and 23 in Non Caucasian cystic fibrosis patients from the north of Iran
Medical GeneticsCystic fibrosis (CF) is the most common autosomal recessive disease in Caucasians, caused by mutation in cystic fibrosi...Read more
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Blood porphyrin fluorescence peaks and its diagnostic value for early colorectal cancer (CRC) detection
Cancer; Prevention, Diagnosis and TreatmentPorphyrins are precursors of Heme metabolism. Any metabolic disorder like cancer can highly affect their level. Since th...Read more
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The role of natural antioxidants in treatment of cancer
Cancer; Prevention, Diagnosis and TreatmentCancer is one of the most common causes of death in advanced industrial societies. With the prevalence and spread of can...Read more
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Fabrication and optimization of polymeric PAA nanoparticles loaded with the natural antibacterial component, curcumin.
Nano-Biotech MedicalCurcumin is a natural polyphenol molecule derived from the Curcuma longa plant which exhibits anticancer, antioxidant, a...Read more
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Investigating the Epidemiology of Concussed Patients, Hospitalized in Khatam al-Anbyia and Ali ibn Abi Talib Hospitals in Years 95-96
Microbiology and Infectious DiseasesFrom the point of view of frequency and importance, Brain vascularaccidents take the first place among all the neural di...Read more
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A brief review of regenerative dentistry
Stem cell and Medical ApplicationsTissue regeneration idea has been formed by stem cells identifying and tissue engineering techniques. Stem cells can be ...Read more
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Detecting of herpes simplex virus’s DNA in the breast tumor, using polymerase chain reaction technique
Medical GeneticsIt has been proven that cancer cells formation can be due to the herpes simplex virus infection in human beings. The ai...Read more
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Detection of Hepcidin biomarker in plasma of patients with stomach tumor before and after treatment
Cancer; Prevention, Diagnosis and Treatment: cancer is a very important public health problem, which is the main cause of death inindustrialized countries and incr...Read more
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The Approaches for Salivary Glands (SGs) Regeneration: a review
Stem cell and Medical ApplicationsSaliva is secreted from three pairs of major SGs and 100–800 minor SGs and plays a vital role in oral and general heal...Read more
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Evaluation of nitrosative stress in sprayer workers
Metabolism and Metabolic DiseasesAgricultural pesticides have an important impact on human health and farmers are people who are more exposed to pesticid...Read more
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The Effects of MicroRNAs on Bone Regeneration and Differentiation
Medical GeneticsOne of the promising approaches for osteoporosis treatment is bone regeneration. In this case, several therapeutic optio...Read more
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Prevalence of Cysticercus bovis in Cattle slaughter-house in Piranshahr city, Iran (2011-2115))
Microbiology and Infectious DiseasesCysticercus bovis are the intermediate stage in the life cycle of a human tapeworm (Taenia saginata). Cysticercus bovis ...Read more
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Investigating the toxicity of PEGylated Gold Nanoparticles and red LED light on Ecoli bacteria
Nano-Biotech MedicalToday, the emergence and spread of antibiotic-resistant strains of bacteria have become a major challenge to public heal...Read more
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Evaluation of gonadotropin hormones in non-obstructive azoospermia patients
Women and Reproductive HealthInfertility refers to the inability of couples to achieve a successful pregnancy after a year of sexual intercourse with...Read more
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Pregnancy management in Iranian Traditional Medicine
Women and Reproductive HealthManaging complications in pregnancy is so important cause of sensitive situation of the mother and the fetus. Physicians...Read more
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Anti-Diabetic Effects of Methanolic Extract of Calendula officinalis through Increased Antioxidant Enzymes Activity
Metabolism and Metabolic DiseasesDiabetes is a big challenge in the health care system. ROS generation is the major mechanisms which is involved in the p...Read more
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Study of MiRNA-873 expression in Ectopic pregnancy, Endometriosis and Ovarian cancer (review)
Medical GeneticsMicroRNAs are small non-coding RNA molecules that have functions in post-transcriptional regulation of gene expression. ...Read more
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Evaluation of Interleukin 10 Gene Promoter Polymorphisms of -592A/C and -1082A/G Region Among Obese Individuals with Type 2 Diabetes in Alborz Province
Metabolism and Metabolic DiseasesToday diabetes is one of the most prevalent noncontagious diseases around the world. There is strong evidence showing in...Read more
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Study of properties of Juglans regia plant on women’s health
Women and Reproductive HealthJuglans regia plant is one of Iranian native plants that some of it’s productive types are in Markazi province. The b...Read more
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Intervention of Dopamine D2 Receptors in Regulating the Serum Lipid Profile in Male Rats under Food Restrictions
Nutrition and HealthStudies have indicated that reduced energy consumption mostly has a significant effect on the reduction of blood lipids...Read more
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Anticonvulsant, neuroprotective and behavioral effects of magnesium sulfate on pentylenetetrazol-induced seizures in male Wistar rats
Nutrition and HealthMagnesium (Mg2+) is the second most abundant divalent and ubiquitous intracellular cation in mammalian cells and an ess...Read more
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Expression of CD74 in Ovarian cancer
Medical GeneticsOvarian cancer is a cancer that forms in or on an ovary. The pro-inflammatory cytokine migration inhibitory factor (MIF)...Read more
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Investigating the Verification of the Personnel Hand Hygiene Dividedly among Five Situations in Intensive Working in Namazi Hospital of Shiraz
Microbiology and Infectious DiseasesHand hygiene behavior divides into two categories: the innate hand hygiene and the selective hand hygiene. The innate ha...Read more
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Invitro Effect of Probiotics, Paraprobiotic and Postbiotics of Locally Isolated Lactobacillus casei strains on Colon Cancer Cell Lines
Microbiology and Infectious DiseasesA number of lactic Acid Bacteria (LAB) produce bacteriocin which are bioactive peptides active against a number of path...Read more
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Apoptotic Effect of Tamoxifen on Hepatocellular Carcinoma Hep G2 Cell Line
Cancer; Prevention, Diagnosis and TreatmentHepatocellular carcinoma (HCC) is the sixth most common cancer, and the third most common cause of cancer-related death...Read more
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the effect of crocin on forgetfulness caused by cholestasis in male rats(behavioral , biochemical and genetical )
Metabolism and Metabolic Diseasescholestasis is a condition in which the bile ducts that carry bile from the liver to the intestine to dispose, is blocke...Read more
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Review: ASD heritability
Medical GeneticsAutism Spectrum Disorder (ASD) is one of the most common neurodevelopmental disorders; due to its high occurrence rate a...Read more
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Prevalence of beta-lactam resistant isolates of Enterobacteriaceae in clinical specimens
Microbiology and Infectious DiseasesBackground: The emergence of extended-spectrum beta-lactamase (ESBL) producing isolates of Enterobacteriaceae has impor...Read more
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Skin anti-ageing potential of Lactobacilli exopolysaccharides (EPSs) on human fibroblast
BeautySkin aging is a complex biological process influenced by a combination of endogenous or intrinsic and exogenous or extri...Read more
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Detection of Mycoplasma arginini contamination in biological products by PCR
Microbiology and Infectious DiseasesIntroduction: Mycoplasmas are one of the most important pollutants in biological products and cell cultures, and are a...Read more
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Examination of mutations in QRDRs in ParC, ParE genes Salmonella Clinical Examples of Zahedan Hospitals
Microbiology and Infectious DiseasesSalmonellosis is a major public health problem worldwide. Although most Salmonella infections result in mild self-limiti...Read more
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studying the effect of silibinin in some of hippo signaling pathway genes , in T47D and MCF7 Breast cancer cell lines with 3D culture.
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is one of the most common malignancy diseases world and is the second leading cause of cancer in women. S...Read more
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Can air pollution impact of sperm parameters? A meta- analysis
Women and Reproductive HealthAir pollution is common in all countries and affects reproductive functions in men and women. It particularly impacts sp...Read more
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Naltrexone changes the expression of lipid metabolism-relatedproteins in the endoplasmic reticulum stress induced hepatic steatosis in mice
Metabolism and Metabolic DiseasesEndoplasmic reticulum (ER) stress is closely associated with several chronic diseases such as obesity, atherosclerosis, ...Read more
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Tamoxifen-induced rapid death of GPER positive cell lines by modulating RAS/MAPK signaling pathway
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the most common cancer in women worldwide. Tamoxifen is a nonsteroidal selective estrogen receptor modu...Read more
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The role of long non-coding RNAs in hematologic malignancies
Cancer; Prevention, Diagnosis and TreatmentLong noncoding RNAs(lncRNAs) are a novel heterogeneous group which refer to non-coding RNA molecule ranging in length fr...Read more
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Computational analysis and design of crRNA for post transcriptional regulation of metastamiR-10b and metastamiR-126 by CRISPR-C2C2 technique.
Medical GeneticsOne of the important causes of death in cancer patients is metastasis. Recently have been shown that specific group of m...Read more
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CRISPR/Cas9-mediated gene Knockout
Cancer; Prevention, Diagnosis and TreatmentGenome engineering is a novel and powerful tool for biotechnological applications. The development of the Clustered Regu...Read more
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Survey of various aspects in polycystic ovary syndrome (PCOS)- A review
Women and Reproductive HealthPolycystic ovary syndrome (PCOS) is a complex endocrine disorder affecting 5–10% of women of reproductive age. It has ...Read more
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Antimicrobial effects of new designed 2-amino-tetrahydro-4H-chromene-3-carbonithril derivatives against some pathogenic microbial strains
Microbiology and Infectious DiseasesChromenes are natural compounds which also called benzopyrane derivatives and chromene-4-one and had several biological ...Read more
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Association Chlamydia trachomatis infection and TNFα -308 polymorphism in abortion
Microbiology and Infectious DiseasesSeveral bacterial infections such as Chlamydia trachomatis and host genetic background, including TNFα SNP polymorphism...Read more
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Effect of Valproic Acid on Proliferation and Apoptosis of Colon Cancer HT 29 Cell Line
Cancer; Prevention, Diagnosis and TreatmentThe structure of chromatin is made up of DNA, histones, and non-histone proteins with the basic repeating unit, nucleoso...Read more
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Study genetic susceptibility polymorphisms for chronic lymphocytic leukemia in Iranian population.
Medical GeneticsChronic lymphoid leukemia (CLL) is the most common form of leukemia found in adults. CLL is a monoclonal disorder that w...Read more
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Discrimination of Leishmania species by Arginine permease gene AAP3as a suitable molecular tool for detection and genetic proximity analysis
Microbiology and Infectious DiseasesLeishmaniasis presents itself in different clinical manifestations such as: visceral Leishmaniasis, Cutaneous Leishmania...Read more
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Kisspeptin decreases mean serum adiponectin concentrations in rats
Women and Reproductive HealthKisspeptin/GPR54 signaling system is one of the most important pathways of hypothalamus for regulating reproductive proc...Read more
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The impact of the vaginal probiotic lactobacillus on the prevention and treatment of cervical cancer
Cancer; Prevention, Diagnosis and TreatmentToday, cervical cancer is the second most common cancer after breast cancer among women and it`s considered dangerous ...Read more
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Role of Potential tumor marker in several cancer: Diagnostic and Treatment
Cancer; Prevention, Diagnosis and TreatmentTumor markers are substances produced by the tumors or by other cells of the body in response to cancer. They are produc...Read more
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The salivary beta-2microglobulin (β2M) and prostate-specific antigen (PSA) can be used as an alternative to the serum β2M and PSA for diagnosis and monitoring of prostate diseases
Cancer; Prevention, Diagnosis and TreatmentIn recent years, the use of saliva as a specimen, due to its non-invasive and easy access increased. But their roles hav...Read more
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study of promoter methylation status of pax5 gene in patients with gastric cancer
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is the fifth leading cause of cancer and is also the third leading cause of death in the world .Although ...Read more
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Comprehensive databank of Iranian patients with Noonan syndrome
Medical GeneticsNoonan syndrome (NS) (OMIM 163950) considered as a relatively common (1/1000-2500), developmental, multi-organ and compl...Read more
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Investigation of antioxidant capacity of silver nanoparticles with Laurencia caspica seaweed on liver cancer cell line (HepG2)
Nano-Biotech MedicalHepatocellular carcinoma is a type of hepatocellular carcinoma that occurs most often in cases of hepatitis B and C, or ...Read more
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Evaluation of the HLA-B46 Allelic frequency in the patients with spondyloarthritis syndrome in zanjan province
Medical GeneticsSpondyloarthritis is a group of multi-systematic disorders that has been created by spinal features, peripheral jointsan...Read more
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Bioinformatics evaluation of hsa-miR-548g related to single nucleotide polymorphism (rs1803622) of GAPDH gene in patients suffering from breast cancer
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is one of the most prevailing cancer among females. GAPDH gene is located on chromosome l on position of G...Read more
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Lack of association between Hypoxia Inducible Factor rs11549465 polymorphism and Preeclampsia
Medical GeneticsPre-eclampsia (PE) is an obstetric disorder that may result inmaternal and neonatal mortality and morbidity. Placental h...Read more
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Effects of serotonin on adiponectin secretion and leptin gene expresions in rats
Women and Reproductive HealthSerotonin is a neurotransmitter which stimulates the secretion of sexual hormones . The nuclei of Hypothalamus involved...Read more
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Prevalence of septicemia in Intasive care unit and Internal medicine wards patients in Rajaee Hospital of Karaj
Microbiology and Infectious DiseasesSepticemia or blood infections is One of the most important causes of death in patients hospitalized in different parts...Read more
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Survey of beta-lactam hydrolyzing enzymes in Pseudomonas spp. isolated from hospital sewage
Microbiology and Infectious DiseasesBackground: Beta- lactams are the largest group of antibiotics used by hospitals to treat infections caused by Gram-nega...Read more
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Molecular Cloning of Clostridium perfringens Type D & Clostridium septicum vaccine strain epsilon alpha fusion gene in E. coli
Medical GeneticsDesigning and producing a proper fusion construction is the most important problem of producing large quantities of fu...Read more
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Evaluating the genetic variations in functional domains coding regions of MSMB in infertile men with unexplained infertility
Medical GeneticsΒ-Microseminoprotein(MSMB) is one of the most abundant proteins in human seminal plasma. This protein binds to head and...Read more
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Doxycycline loaded Kefiran nanofibers: cell viability improvement
Nano-Biotech MedicalDoxycycline (DOXY) is a second generation tetracycline antibiotic with extensive usage. High concentration of DOXY might...Read more
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Evaluation of cytotoxicity of rainbow trout extracts (Oncorhynchus mykiss) on gastric cancer cell line (AGS)
Cancer; Prevention, Diagnosis and Treatmentrainbow trout due to high levels of essential fatty acids, omega-3 has been identified as one of the important factors i...Read more
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Microfluidic 3D cell-Culture platforms for drug response monitoring: potential applications for individualized cancer treatment
Cancer; Prevention, Diagnosis and TreatmentIndividualized monitoring of drug response is supposed as a main constituent of personalized treatment. Current methods ...Read more
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Survey of the Relationship between Two Polymorphisms at Position T677C and C1298A in MTHFR Gene with ADHD in Tehran Children
Medical GeneticsAttention deficit hyperactivity disorder is one of the most common behavioral disorders in children, which is associated...Read more
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Anemia, a common disease in hemodialysis patients
Metabolism and Metabolic DiseasesChronic renal failure stage of renal insufficiency it is said that all the no longer able to repel and not toxic waste a...Read more
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The relationship between serum creatinine and creatinine clearance with the occurrence and severity of coronary artery disease
Metabolism and Metabolic DiseasesCardiovascular diseases are thought to be the most important reason of mortality around the world. Among them coronary a...Read more
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Therapeutic effect of Human Tumor Necrosis Factor Receptor-2 on collagen -induced arthritis in Balb/c mice
Metabolism and Metabolic DiseasesRheumatoid arthritis (RA) is a chronic, systemic, immune-mediated inflammatory disease associated with decreased life ex...Read more
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Evaluation of the level of some of the Trace elements in the sprayer workers
Metabolism and Metabolic DiseasesPesticides and toxins have deleterious effects on human health and can affect the biochemical factors of the body. There...Read more
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Overexpression of cancer stem cell protein, Piwil2, promotes the expression of anti-apoptotic and proliferative genes in the gastric cancer cell line MKN-45
Cancer; Prevention, Diagnosis and TreatmentPiwi-like RNA-mediated gene silencing 2 (Piwil2) is an oncogene that is highly expressed in different tumors including ...Read more
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Suppression of interfering predominant bacteria in purification of Myxobacteria
Microbiology and Infectious DiseasesMyxobacteria have recently gained attention due to the ability to produce numerous biological active metabolites. Applyi...Read more
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Investigation of KLF1 gene and It's affection on thalassemia minor patients
Medical Genetics: Thalassemia is a type of hereditary autosomal recessive disorder in which the existing genetic defect reduce the amoun...Read more
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Design And Application Of A Loop-Mediated Isothermal Amplification (LAMP) Assay For Detection Of Tick Borne Relapsing Fever
Medical GeneticsTick borne relapsing fever (TBRF) caused by Borrelia microti is transmitted via bites of the soft tick Ornithodoros erra...Read more
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Anti-clostridial role of probiotics in prevention and treatment of Clostridium difficile infections
Microbiology and Infectious DiseasesPatients with varied conditions, such as Antibacterial therapy, Cancer chemotherapy, and gastrointestinal surgery are at...Read more
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Association of rs699 Polymorphism in AGT Gene with Coronary Heart Disease Risk
Medical GeneticsThe rs699 transition in human angiotensinogen (AGT) gene, result in methionine (M) to threonine (T) substitution at codo...Read more
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evaluation of anti-mullerian hormone in daughters of women with polycystic ovary syndrome
Women and Reproductive HealthPolycystic Ovary Syndrome(pcos) is one of the most common endocrine diseases among women during their fertility years . ...Read more
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The prevalence of adeABC encoding genes among Acinetobacter baumannii carbapenem resistant clinical isolates.
Microbiology and Infectious DiseasesAcinetobacter baumannii is the important cause of nosocomial infections worldwide due to its propensity to rapidly acq...Read more
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Insulin resistance in addicted people: experimental study along with in vitro study and data mining Techniques
Metabolism and Metabolic DiseasesThis study was planned to survey the inflammatory and antioxidant and other Insulin Resistance related condition in addi...Read more
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The effect of Rosa canina extract on Bax gene expression in gastric adenocarcinoma cell line(AGS)
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is the most common cancer in the world. It occurs as a result of many factor and there is massive invest...Read more
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Molecular study of 92 fetal of couples with recurrent abortion in Mazandaran
Medical GeneticsChromosome abnormalities has recognized as a major factor contributing to pregnancy loss and accounted for about 50% of ...Read more
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Braest cancer micrometastatic detection in sentinele lymph nodes using molecular marker
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is prevalent malignancy among women in worldwide (1). Molecular diagnosis is recently proposed as a sensit...Read more
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CLONING AND EXPRESSION OF an antibody fragment (scFv) against PcrV protein of Pseudomonas aeruginosa in fed-batch cultivation mode
Microbiology and Infectious DiseasesPseudomonas aeruginosa is a major cause of hospital-acquired infections, particularly in mechanically ventilated patient...Read more
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Role of Immune system in treatment of cerebral palsy by stem cells
Stem cell and Medical ApplicationsCerebral Palsy (CP) is known as a non-progressive brain disorder that occurs due to injuries or abnormalities in develop...Read more
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Prognostic significance of c-Myc gene amplification and protein expression in brain tumors: Astrocytoma and meningioma
Cancer; Prevention, Diagnosis and TreatmentAstrocytoma and meningioma are the most common primary brain tumors. c-Myc as a member of MYC proto-oncogenes has recent...Read more
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Infections Associated with Bacterial Biofilms and Treatment Problems
Microbiology and Infectious DiseasesMicrobial biofilms are seen in 65% of human infections. Bacteria in biofilms society are resistant against antibiotics. ...Read more
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NEW CONCEPTS IN THE IMMUNOPATHOGENESIS OF MULTIPLE SCLEROSIS
Medical GeneticsMultiple sclerosis (MS) is a chronic disorder of the central nervous system characterized by autoimmune inflammation, de...Read more
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Design and evaluation of a selective delivery system to induce antimiR-155 function
Nano-Biotech MedicalDeveloping RNA/DNA aptamer-miRNA chimera represents an effective approach in targeted gene therapy of cancer. In additio...Read more
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The effect of berberin on histone H1 in lung cancer A549
Cancer; Prevention, Diagnosis and TreatmentBerberin, a naturally occurring isoquinoline alkaloid, is present in a number of important medicinal plants. Berberin ha...Read more
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Effect of hydroalcoholic leaf extract of Ziziphora tenuior L. on pain in male rats
Microbiology and Infectious DiseasesZiziphora tenuior is one of the traditional medicinal herbs; the main active chemical composition of this herb is an ing...Read more
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Investigating the antitumor activity of PNU-74654 as Wnt/β-catenin inhibitor, alone or in combination with gemcitabine in MiaPaCa-2 pancreatic cancer cell
Cancer; Prevention, Diagnosis and TreatmentWnt/beta-catenin pathway is one of the key dysregulated pathways in several malignancies, including pancreatic cancer (P...Read more
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Design, production and purification of polyclonal antibodies against recombinant human erythropoietin antigens for immunological investigation of pharmaceutical and clinical samples
Nano-Biotech MedicalIn this research, the primary antibody against erythropoietin is produced by injecting pure recombinant human erythropoi...Read more
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Shedding light on new form of combination therapy in acute promyelocyte leukemia
Cancer; Prevention, Diagnosis and TreatmentAlthough physicians have taken a variety approaches for the treatment of acute promyelocytic leukemia (APL), there is no...Read more
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Comparison of in vitro survival of mononuclear cells derived from B-CLL patients with or without BAFF & APRILL cytokines
Cancer; Prevention, Diagnosis and TreatmentThis article studies the antiapototic effect of cytokines BAFF & APRIL on the survival of mononuclear cells derived ...Read more
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The Anticancer Effect of Plant Aqueous Extracts of Aloe Vera in Gene Expression Bax and Bcl-2 on Gastric Adenocarcinoma AGS Cells
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is a major cause of cancer death. In terms of incidence is the fourth most common cancer and the second l...Read more
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Controversy in reports about TNF-α (rs361525) related to susceptibility to Hepatocellular Carcinoma (HCC): a meta-analysis
Cancer; Prevention, Diagnosis and TreatmentTumor necrosis factor-α play a very important role in the development and progression of hepatocellular carcinoma. Pre...Read more
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T cell engineering for cancer imenuterapy
Cancer; Prevention, Diagnosis and TreatmentWith regard to the prevalence of cancer in the world, treatment have become important. One of the methods is to stimula...Read more
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Operational study of plastination as an alternate method for dissection
Nano-Biotech MedicalSince, two-thirds of the approved Zoology Laboratory syllables, defined by the Ministry of Science, Research and Technol...Read more
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Correlation of umbilical coiling index and HbA1C in gestational diabetes mellitus (one-step strategy).
Metabolism and Metabolic DiseasesGestational diabetes mellitus [GDM] is a prevalent and potentially serious condition which may put mothers and fetuses a...Read more
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Cloning and expressing the chimeric peptide lactoferricin-lactoferampin camel in Lactococcus lactis for promising as a candidate for oral medication
Nutrition and HealthLactococcus lactis is known as probiotics due to its lack of harmful toxins. Because of its high growth potential and re...Read more
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The Study of the Requested Antibiotics during Each Patient’s confining to Bed in Namazi 1000 beds hospital, May 22nd to July 21st
Microbiology and Infectious DiseasesOccurring resistive microbial trends is one of basic obstacles in infection disease treatments. Prescribing too much ant...Read more
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Cell-Penetrating Peptides and Tumor Targeting Peptides: achievements and challenges in application for cancer treatment
Cancer; Prevention, Diagnosis and TreatmentDespite significant advancement in the anti-cancer drugs recently, cancer still remains one of the leading causes of dea...Read more
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Experimental and theoretical investigation on Mandelic acid (R, S) enantioselective separation using Vancomycin chiral column in high performance liquid chromatography
Nano-Biotech MedicalNowadays, antibiotic chiral columns can be used in various chromatography separations. The high potential of these compo...Read more
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A review: Runt-related transcription factor 2 (RUNX2) and its signaling pathways in cardiovascular complications.
Metabolism and Metabolic DiseasesVascular calcification (VC) is a process similar to bone mineralization. VC has been observed in chronic kidney disease,...Read more
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Curcumin regulates proinflammatory signaling function of thrombin in endothelial cells
Microbiology and Infectious DiseasesCurcumin regulates proinflammatory signaling function of thrombin in endothelial cells...Read more
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The nutritional benefits of Pistacia atlantica
Nutrition and HealthPistacia Atlantica Mutica is a genus of the family Anacardiaceae which consist of different parts such as fruit, leave a...Read more
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personalized medicine in oncology
Medical GeneticsThe term peronalized medicine is used for the identification of optimal drug type and optimal drug dosage for individual...Read more
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Combinatorial therapy of anti-Treg vaccine associated with anti-tumor DC vaccine in mice tumor therapy
Cancer; Prevention, Diagnosis and TreatmentRegulatory T cells (Tregs) obviously have a crucial role in attenuation of anti-tumor immune responses. Application of r...Read more
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Evaluation of nitrate and nitrite content in meat and meat products and their role of these substances in carcinogenesis
Cancer; Prevention, Diagnosis and TreatmentBecause of N-nitrous compounds formation in meat and meat products, There is a direct correlation between high consumpt...Read more
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the role of genetics in diabetes and its complications
Medical GeneticsThe purposes of writing this article are the significant role of genetics in the onset of diabetes, hoping to be treated...Read more
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Phylogenetic and Bioinformatics analysis of Interferon beta-1 Protein
Medical GeneticsInterferon beta-1b protein is used to improve MS disease and reduce the number of attacks in patients. The purpose of th...Read more
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Survey of Changes gene expression levels of SAP 1-3 Candida albicans samples treated with treated with Fluconazole-loaded PLGA Nanospheres, in comparsion with drug Fluconazole
Microbiology and Infectious DiseasesSecreted Aspartyl Proteinase (SAP) is one of the main virulent factors in the pathogenesis of Candida. This enzyme is en...Read more
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In silico analysis of Siglec14 as a target for hsa-let-7e-5p
Medical GeneticsSialic acid-binding immunoglobulin-type lectins (Siglecs) are transmembrane proteins that are expressed on the cell surf...Read more
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Production of protein A containing Thiol Group for binding to fluorescence dye To increase the sensitivity of antibody detection
Nano-Biotech Medicalstaphylococcal Protein A is a cell wall component which has the ability to bind to immunoglobulins of different animal s...Read more
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miR-214 induces insulin resistance in C2C12 cell line though targeting Rock1 and Akt2 gene expressions
Metabolism and Metabolic DiseasesMicro-RNAs (miRNAs) are a class of post-transcriptional regulators that play crucial roles in various biological process...Read more
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Diagnosis of Cytomegalovirus in Sinusitis by Molecular method
Microbiology and Infectious DiseasesCytomegalovirus is one of the important viruses that can cause a wide range of diseases in humans. Sinusitis is a common...Read more
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Cloning of Human THAP11 Gene in Lentiviral Vector
Stem cell and Medical ApplicationsThap11, the most recent described member of THAP domain family, which is in volved in cell proliferation and described a...Read more
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Non-syndromic obesity in infertile men and structural chromosomal abnormalities
Medical GeneticsObesity is commonly classified into subgroups depending on suspected etiology: monogenic obesity (extremely severe obesi...Read more
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Toll-like receptor 4 mediates cross-talk between peroxisome proliferator-activated receptor γ and nuclear factor-κB in mouse melanoma (B16F10) in vitro
Cancer; Prevention, Diagnosis and TreatmentThere is increasing evidence that chronic activation of nuclear factor-κB (NF-κB), which is an essential signaling pat...Read more
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A genetic variant in CDKN2A/2B locus was associated with poor prognosis in patients with esophageal squamous cell carcinoma
Cancer; Prevention, Diagnosis and TreatmentEsophageal squamous cell carcinoma (ESCC) is among the leading causes of cancer related death. Despite extensive efforts...Read more
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COMPARATIVE STUDY OF OLERACEIN E AND OLERACEIN L EFFECTS ON ANTI OXIDANT ACTIVITY, ANTI DIABETIC INDICATORS AND DAMAGE BIOMARKERS LEVELS IN PANCREATIC CELL LINE
Nutrition and HealthThe medicinal plants have valuable biochemical effects. The aim of this study was to assess the effects of Oleracein E a...Read more
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The giant lipoma pediculated in the falciform ligament: a case report
Cancer; Prevention, Diagnosis and TreatmentIntroduction: Lipoma is one of the benign and common tumors of the limbs and trunk that’s rarely occurs in the abdomin...Read more
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Characterization of a produced monoclonal antibody against testis antigens on the mouse embryogenesis
Medical GeneticsThe complex series of cellular signaling molecules and transcriptional factors are involved in differentiation and devel...Read more
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Lack of association between TNF-α rs1800629 polymorphism and Hepatocellular Carcinoma: a meta-analysis
Medical GeneticsTumor necrosis factor a (TNF-α) is a pleiotropic cytokine which can regulate a wide variety of cellular responses. Low ...Read more
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Down-Regulation of Bcl-2 and Mcl-1 by MiRNA-15 and 16 Synergistically Enhances the Apoptotic Effects of ABT-199 and Fludarabin in CLL Cells
Cancer; Prevention, Diagnosis and TreatmentMiRNA-15 and 16 can act as a tumor suppressor gene by interfering with Bcl-2 and mcl-1. Studies have demonstrated that o...Read more
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In silico evaluation of anti-retroviral effects of lactoferrin from different species
Microbiology and Infectious DiseasesLactoferrin (LF) is an iron binding glycoprotein that is present in body fluids and mucosal secretions. Antimicrobial pr...Read more
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Influence of CYP2D6 and CYP3A4 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia and treatment response
Cancer; Prevention, Diagnosis and TreatmentXenobiotic- metabolizing enzymes compose an important line of defence against a variety of carcinogenes and environmenta...Read more
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The association between pre-gravid BMI with fasting glucose and lipid profile in gestational diabetes following Assisted Reproduction.
Women and Reproductive HealthGestational diabetes mellitus (GDM) is one of the most endocrine pregnancy outcomes. High prevalence of GDM was reported...Read more
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Effect of Praziquantel Drug on Prevention of Afflicting Dogs with Cestode Echinococcus Granulosus
Microbiology and Infectious DiseasesAwareness of the impact range of praziquantel drug on prevention of afflicting dogs with echinococcus granulosus parasit...Read more
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NRG1 expression changes in Autism spectrum disorder and play role in executive functions abnormalities
Medical GeneticsAutism spectrum disorder (ASD) is a pediatric heterogeneous psychiatric and neurodevelopment disorder with social and co...Read more
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A novel role for stem cells in anxiety disorders treatment
Stem cell and Medical ApplicationsAnxiety disorders are the most common mental disorders which has affected one-eighth of the world's population. Patients...Read more
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The effect of Bioactive glass on Adipose-derived MSC osteogenesis in 3D cultures
Stem cell and Medical ApplicationsRegenerative medicine is an emerging field of biotechnology that combines various aspects of medicine, cell and molecula...Read more
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Epigenetic Mechanisms as Therapeutic Targets
Medical GeneticsEpigenetics, in conjunction with genetic mechanisms, determine the biological fate of cells and living organisms. epig...Read more
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Pharmacogenomics in Multiple sclerosis
Medical GeneticsMultiple sclerosis is a chronic inflammatory disease in the central nervous system. The most effective drugs for MS pat...Read more
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The Use of Viruses to Treat Cancer
Cancer; Prevention, Diagnosis and TreatmentCancer is an abnormal growth of cells that have lost normal control mechanisms and are able to expand continuously, inva...Read more
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Therapeutic effects ellagitannin on non communicable diseases
Nutrition and HealthToday, due to the complications caused by the treatment with chemical drugs, the scientists focus on to use of complemen...Read more
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EFFECT OF CHRYSIN NANO-PARTICLES TREATMENT ON ESTROGEN RECEPTORS EXPRESSION LEVELS IN BREAST CANCER CELL LINE
Nano-Biotech MedicalBreast cancer (BC) is increasing in the developing countries. Estrogens are supposed to play roles in BC initiation and ...Read more
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Isolation and identification of probiotic bacteria from human milk
Microbiology and Infectious DiseasesBackground: Breast milk is the best nutritional supplement during the first few months of the baby's life. It contains v...Read more
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Effect of letrozole as alternative aromatase inhibitor on development of ovarian follicles and uterine changes in adult NMRI mice strain and their infants
Microbiology and Infectious DiseasesLetrozole is used as an aromatase inhibitor, to increase ovulation induction. This drug is usually prescribed for patien...Read more
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Evaluation of selenium & zinc levels and antioxidant power in serum of women with endometriosis before and after administration of N-Acetylcysteine
Women and Reproductive HealthEndometriosis is characterized by the presence of glands and endometrial stroma outside the uterine and affects approxim...Read more
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study of microbial quality of some food samples
Nutrition and Healthbacterias are considered as the most important factor to cause infection and food poisoning ,so that microbial contamina...Read more
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Interaction of rs783540 of CPEB1 gene in patients with azoospermia
Medical Genetics: Publicly, 90% of fertile couples get pregnant in one year. Therefore, infertility refers to disability in pregnancy, a...Read more
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Promoter Hypermethylation Analysis of the Tumor Suppressor Gene RASSF1A in Iranian Endometrial Carcinoma Patients
Cancer; Prevention, Diagnosis and TreatmentEndometrial cancer is the most common malignancy among women in developed countries. More endometrial cancers occurs in ...Read more
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Investigating the relationship between metacognitive beliefs, and premenstrual syndrome and depression caused by that, in female students studying at Tehran University of Medical Sciences
Women and Reproductive HealthThe purpose of this research was studying the relation between meta-cognitive beliefs on premenstrual syndrome and depre...Read more
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Design, modeling and simulation of a novel immunotoxin structure affective against gastrointestinal malignancies
Cancer; Prevention, Diagnosis and TreatmentGastrointestinal malignancies comprise a remarkable proportion of cancer deaths each year. Although many drugs have been...Read more
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Design and evaluation of a colorimetric method for rapid determination of minimal inhibitory concentration of the bacteria belonging to Enterobacteriace
Microbiology and Infectious DiseasesIsolation of antibiotic resistant pathogenic bacteria in clinic may pose the serious problems. So a rapid method capabl...Read more
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MYH9 gene and urinary albumin excretion in Iranian diabetic patients
Medical GeneticsDiabetic nephropathy (DN) is one of the most common causes of end stage renal disease (ESRD).: Myosin heavy chain 9 (MYH...Read more
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The effects of nano-liposomes containing curcumin on the lung cancer cell line.
Nano-Biotech MedicalLung cancer is one of the most common and malignant cancer in both sexes. The prevalence and spread of cancer in iran an...Read more
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The Role of Nanobiotechnology in Identification and Treatment Lung Cancer
Nano-Biotech MedicalNanotechnology is the engineering of functional systems at the molecular scale. Therefore, it is possible to combine nan...Read more
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Biosynthesis of Tellurium nanoparticles by Streptomyces isolate B2.1369F
Nano-Biotech MedicalBiosynthesis of Tellurium nano particles (TNPs) has great advantage since it has no chemical contamination in the enviro...Read more
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Silver nanoparticles potential as an adjuvant in antimicrobial therapies against multidrug resistant bacteria
Microbiology and Infectious DiseasesThe emergence and rapid spread of multidrug-resistant (MDR) isolates of pathogenic bacteria causing nosocomial infection...Read more
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Gankyrin expression in ovarian cancer and its correlation with clinicopathological parameters
Cancer; Prevention, Diagnosis and TreatmentGankyrin (p28GANK) is a novel oncoprotein which regulates the phosphorylation of retinoblastoma protein (pRb) and degrad...Read more
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Synthesis of pH-sensitive micelles based on F127-Dox conjugated for drug delivery to cancer cells
Nano-Biotech MedicalA variety of nano-systems constituted by polymer–drug conjugates have been designed to overcome its shortages on water...Read more
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Influence of matrix rigidity on the differentiation of mesenchymal stem cells in response to TGF-β
Stem cell and Medical ApplicationsBone marrow human mesenchymal stem cells (hMSCs) are an appreciated cell source for tissue engineering and regenerative ...Read more
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Selection of Peptides Specific to PDL-1 Using Phage Display Technology
Cancer; Prevention, Diagnosis and TreatmentPDL-1 is a well-known antigen to target tumor specifically. It can interact with PD-1 receptor on tumor infiltrating T-l...Read more
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Gene Editing: As a new treatment for HIV
Medical GeneticsCurrent treatments in HIV treatment don’t eliminate the low level of viral replication in latently infected cells, whi...Read more
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Enrichment analysis of hsa-miR-320b-1 most related pathways in cancer
Cancer; Prevention, Diagnosis and TreatmentIntroduction: Cancer is a complex disease in which the expression of the gene is unbalanced. MicroRNAs are a group of no...Read more
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Investigation of prevalence class 1 and 2 integron gen in Escherichia coli from Isolated clinical samples Tehran’s hospitals
Microbiology and Infectious DiseasesAs the antibiotics are misused, Integrons are the moving genetic factors which carry resistance gens and have an import...Read more
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Effect of Velcade in Combination with Nanocurcumin in Breast Cancer 4T1
Nano-Biotech Medical: It is well known that breast cancer has the highest incidence rates of about 30% of all types of cancer in women, and ...Read more
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Evaluation of H.pylori drug resistance to current cure in North-West of Iran
Microbiology and Infectious DiseasesAlmost half of the world population is infected with Helicobacter pylori, a major risk factor for chronic gastritis, pep...Read more
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Comparison of Antibacterial Activity of Essential Oil of Varieties of Calendula Plant from Varamin (Iran) on Escherichia coli and Staphylococcus aureus
Microbiology and Infectious DiseasesUncontrolled use of conventional antibiotics and synthetic antibacterial medicine has led to the proliferation of microb...Read more
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Effect of Crocin on mitochondrial biogenesis and Oxidative stress in the Striatum of Cholestatic rats
Medical GeneticsOxidative Stress and increment of Mitochondrial Reactive Oxygen Species (ROS) production that occurs in cholestasis whic...Read more
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Relation between Resilience and Psychiatric Disorders in Patients with Aids in Bandar Abbas Center for Behavioral Diseases
Nutrition and HealthThe AIDS process is very complex and can significantly affect the physical, social, spiritual and psychological health o...Read more
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Evaluation of toxicity of functionalized graphene with ginsenoside Rh2, Lysine and Arginine on RBCs, blood coagulation and cardiovascular tissue: In vitro and In vivo study
Nano-Biotech MedicalIn this study, blood and cardiotoxicity of functionalized graphene with ginsenoside Rh2 (Rh2), Lysine and Arginine was e...Read more
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Modeling of cancer drugs on the route JAK-STAT in cancer stem cells
Cancer; Prevention, Diagnosis and TreatmentAbstract JAK/STAT pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for dev...Read more
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Performing PGD combined with HLA typing on more than 100 blastomeres
Medical GeneticsPreimplantation genetic diagnosis (PGD) is an option for carrier couples who want to assure their child’s health regar...Read more
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Study of Effects of Crushed PLGA Nano-fiber Percentage on The Cell Proliferation in Chitosan-Gelatin-βGlycerophosphate Cartilage Scaffold
Nano-Biotech MedicalArticular cartilage has poor reparative capabilities. So Osteoarthritis is widespread globally in almost 70% of people o...Read more
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Endurance training resulted in significantly greater betatrophin responses compared with resistance training alone, and resistance and endurance exercises combined
Metabolism and Metabolic DiseasesBetatrophin, which recently identified, is a liver and adipose tissue produced hormones that regulates the level of lipi...Read more
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Rosmarinic acid, a Anti-glycation agent, inhibits protein glycation in vitro
Metabolism and Metabolic DiseasesDiabetes mellitus is one of the most non-communicable diseases and is the fifth leading causes of death in most of the d...Read more
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Antibacterial effects of curcumin encapsulated in micelle nanoparticles on mexX gene expression in ciprofloxacin resistant isolates of Pseudomonas aeruginosa in Guilan
Nano-Biotech MedicalCurcumin, a polyphenolic compound fromturmeric (Curcuma longa) is a pharmacologically safe agent that has antibacterial ...Read more
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Evaluation of the HLA-B07 Allelic frequency in the patients with spondyloarthritis syndrome in zanjan province
Medical GeneticsIn 1974 Moll and colleagues established the concept of a group of inter-related disorders originally termed seronegative...Read more
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Determination of antibiotic-resistant strains of isolated Brucella in Markazi Province
Microbiology and Infectious DiseasesBrucellosis is one of the common diseases of man and animals are caused by bacteria of the genus Brucella. The purpose o...Read more
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Identifying Linking Mechanisms of Allergy and Cancer
Cancer; Prevention, Diagnosis and TreatmentAllergy and cancer are prevalent diseases and cause a lot of morbidity and mortality. In recent years, many studies have...Read more
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Detection of methylated DNA based on graphene quantum dot -DNA interaction
Nano-Biotech MedicalEpigenetics is the study of interaction between genes and their expressed product which is controlled by some specific c...Read more
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Evaluation of the effects of fish oil-derived Eicosapentaenoic acid on the proliferation of colorectal cancer cell line (hct116)
Cancer; Prevention, Diagnosis and Treatmentof these studies have indicated that Eicosapentaenoic acid (EPA) can induce apoptosis and reduce proliferation in cancer...Read more
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Assessment of energy and water-soluble vitamins intake in the elderly under health care, Isfahan, Iran
Nutrition and HealthThe B vitamins are essential nutrients to maintain nutritionally healthy body. These water soluble vitamins are critical...Read more
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Thiolated chitosans development and in vitro evaluation of apermeation enhancing oral drug delivery system
Nano-Biotech MedicalThis study investigated the in vitro release of Vancomycin and Amphotericin B fromnovel mocuadhesive chitosan nanofibers...Read more
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Effect of DNA Demethylating Agent Genistein on Epigenetic-modifying Estrogen Receptor Alpha Gene Expression and Apoptosis Induction and also Cell Viability in Hepatocellular Carcinoma HepG 2 cell line
Cancer; Prevention, Diagnosis and TreatmentIn the normal mammalian cells, epigenetic changes such as DNA methylation and histone acetylation play an important role...Read more
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Induction of apoptosis by silibinin in SKBR3 breast cancer cell line through activation of caspase 3/7
Cancer; Prevention, Diagnosis and TreatmentThe poor prognosis of breast cancer is due to its resistance to the conventional treatments. Therefore, researchers are ...Read more
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Self-Concept among Infertile women receiving oocyte donation and Fertile Women
Women and Reproductive HealthOne of the technologies used to assist fertility is oocyte donation. Although there is sufficient information about med...Read more
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Study on protein of leech saliva of Hirudo Oreintalis, Utevsky & Trontelj 2005 in different ages
Nutrition and HealthMedicinal leech, during feeding, enter in host body many bioactive substances that often contain proteins and peptides. ...Read more
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Effect of marjoram extract on sperm concentration and its survival percentage in oxidative-cadmium stress in adult male rats
Nutrition and HealthNutrition Safety and Health is one of the important factors in fertility.Cadmium as an environmental pollutant by free r...Read more
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Study of PAX5 gene expression in patients with gastric cancer
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is one of the biggest health problems in the world. Due to the lack of many carcinogenic biomarkers and t...Read more
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The Possible Role of B. thetaiotaomicron-derived Outer Membrane Vesicles (OMVs) in the Modulation of Cholesterol Uptake and Diet-induced Obesity
Metabolism and Metabolic DiseasesAltered gut microbiota composition has been proven to be associated with several disorders including metabolic syndrome....Read more
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Evaluation of TCA cycle in patients with acute myeloid leukemia
Cancer; Prevention, Diagnosis and TreatmentAcute myeloid leukemia (AML) is the most type of acute leukemia in adults. In solid tumors, alteration of energy metabol...Read more
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Blocking of vascular endothelial growth factor signaling through design of bi-specific single domain antibody
Nano-Biotech MedicalOver-expression of vascular endothelial growth factor (VEGF) leads to the proliferation and neovasculature of cancer cel...Read more
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Investigation of CYP21A2 gene variants in Iranian patients with congenital adrenal hyperplasia
Medical GeneticsCongenital adrenal hyperplasia (CAH) is an autosomal recessive disease characterized by impaired adrenal steroidogenesis...Read more
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Explaining Women's Views on Cervical Cancer: A Qualitative Study
Cancer; Prevention, Diagnosis and TreatmentCervical cancer is the second most common cancer in the world , Which, if detected and treated at early stages, is almo...Read more
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Cytotoxic effect of anticancer drug 5-Azacitidine on hematopoietic stem cells of bone marrow in the presence and absence of Colony stimulating factors
Cancer; Prevention, Diagnosis and TreatmentThe cytosine analogue, 5-Azacitidine as a DNA methyltransferase inhibitor is currently considered the most advanced drug...Read more
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Canavan disease: clinical and molecular review
Medical GeneticsCanavan disease is a rare autosomal recessive disorder that predominantly affects the central nervous system with white ...Read more
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Effects of administration of trimethoprim/sulfamethoxazole and folic acid on ovarian histopathology in adult female rats
Women and Reproductive HealthPrevious studies have reported the antifertility activities of sulfonamides. This study was designed to evaluate the eff...Read more
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Evaluation of Adiponectin Hormone in Diabetic and Non-diabetic Patients
Metabolism and Metabolic DiseasesAdipose tissue is currently considered as a hormonally active system in the control of metabolism and not only as a stor...Read more
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analysis of circulating mir-141, and mir-375 in small cell lung cancer patients
Medical Geneticslung cancer is the main cause of mortality from cancer in the world. small cell lung cancer is the most invasive lung ca...Read more
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Production and evaluation of scFvs against HER2 antigen for breast cancer immunotherapy
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is common cause of women death in the world. There is ErBb2/HER2 in 25%-30% breast cancer cases. Trastuzu...Read more
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Omega-3 and its effects on colorectal cancer
Cancer; Prevention, Diagnosis and TreatmentCancer as the second leading cause of death has always been a threat to human life and due to its peculiar nature and la...Read more
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The effect of Chlorogenic acid on Insulin, GIP and GLP-1 level in healthy humans: A systematic review
Nutrition and HealthAccording to previous studies, there are different supplements in order to prevent and treat diabetes. These studies sho...Read more
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Current Advances in the Genetic Basis of Rheumatoid Arthritis
Medical GeneticsRheumatoid arthritis (RA) is a chronic inflammatory disease characterized by a distinctive pattern of joint involvement ...Read more
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Lantibiotics: New generation of antimicrobial drugs
Microbiology and Infectious DiseasesThese days, due to antibiotic resistance in bacteria, scientists are eager to find new generation drugs. Lantibiotics...Read more
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Evaluation of cytotoxicity of aqueous-ethanolic extract of pineapple on ovarian cancer cells (A2780 cell line)
Cancer; Prevention, Diagnosis and TreatmentToday, the global trend towards the use of herbal medicines for treating diseases has tended, while developed countries ...Read more
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Pattern of efflux pump genes in imipenem resistant Acinetobacter isolates
Microbiology and Infectious DiseasesAcinetobacter species are opportunistic pathogens and responsible for various types of nosocomial infections. They are i...Read more
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An investigation on the structure and function of the cell surface lung-specific antigens for development a new generation of immunotoxins
Cancer; Prevention, Diagnosis and TreatmentLung cancer, with common symptoms such as coughing, weight loss and shortness of breath, is a disease via uncontrolled g...Read more
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Investigation of toxicity effect of 4-Mepgc and 4-No2pgc on the K562 cell line (chronic myeloid leukaemia)
Cancer; Prevention, Diagnosis and TreatmentLeukemia is a particular type of cancer characterized by the failure of cell death or disability in the differentiation ...Read more
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An innovative field of plasma application for medical therapy
Microbiology and Infectious DiseasesPlasma medicine is an innovative and emerging field combining plasma physics, life science and clinical medicine. Recent...Read more
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Investigating the effects of saffron and melatonin with radiotherapy on viability of Hela cells
Cancer; Prevention, Diagnosis and TreatmentNowadays, a lot of people in the worldwide dead because of cancer. Despite much research in this area, there is still no...Read more
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Evaluation of serum lipid profiles and oxidative stress indices in sprayer workers
Metabolism and Metabolic DiseasesDirect or indirect contact with pesticides and toxins leads to some biochemical changes, including increasing the produc...Read more
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The Effect of Educational Intervention on Metabolic Control of Diabetic Patients Referring to the Diabetes Clinic of Shahid Bahonar Hospital in Karaj
Metabolism and Metabolic DiseasesIntroduction: The results of studies on complications and control of diabetes have clearly shown that good metabolic con...Read more
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Synergistic Antibacterial Activity of Zinc Oxide Nanoparticles with Cuminum cyminum L. Essential Oil against the Food-Borne Pathogens Salmonella enterica
Nano-Biotech MedicalOne of the ways to control of pathogenic microorganisms in foods is to use preservatives and antimicrobial agents. Diffe...Read more
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Fast detection of Pseudomonas aeruginosa keratitis by Polymerase Chain Reaction (PCR)
Microbiology and Infectious DiseasesPseudomonas aeruginosa is an opportunistic pathogen that has different virulence factors. This organism is commonly foun...Read more
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Green synthesis of Gold nanoparticles by water extract of common nettle leaves
Nano-Biotech MedicalGold nano particles (AuNPs) are being considered for cancer treatments for targeted drug delivery in pharmacology and me...Read more
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Expression of NAV2 correlated with Change of tumor size in breast cancer patients
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the first leading cause of cancer death among Iranian women and the second worldwide. This type of canc...Read more
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Evaluation of magnesium & copper levels and antioxidant power in serum of women with endometriosis before and after administration of N-acetylcysteine
Women and Reproductive HealthEndometriosis is caused by the presence of ectopic endometrial stromal outside the endometrial cavity. The oxidative str...Read more
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Surface modification of Chitosan nano-fiber by cold atmospheric plasma
Nano-Biotech MedicalSurface modification is the act of modifying the surface of a material by bringing physical, chemical or biological char...Read more
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TP53 hotspot mutations and expression of c-Myc oncogenes in astrocytoma and meningioma
Medical GeneticsMost studies have shown that there are association between the development and malignancy of brain tumors and tumor supp...Read more
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Cytotoxic activity of Berberine on the growth of breast cancer cell line (MCF-7)
Cancer; Prevention, Diagnosis and TreatmentMuch research has been conducted on the benefits of various phytochemicals in many herbs, fruits and vegetables and thei...Read more
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Frequency of Escherichia coli O157:H7 among children with and without diarrhea stool samples referred to microbiology laboratory of shahid Madani Hospital in KhorramAbad during 2016-2017.
Microbiology and Infectious DiseasesEscherichia coli serotype O157:H7, which has been recognized as a food-borne pathogen occurring worldwide in the recent ...Read more
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MOLECULAR DETECTION OF GUT BACTERIA LACTOBACILLUS, BIFIDOBACTERIA, CLOSTRIDIUM DIFFICILE AND YEAST IN BOWEL DISEASE AND CONTROL PATIENTS
Microbiology and Infectious DiseasesTwo kinds of intestinal disorders included inflammatory bowel disease and irritable bowel syndrome have a strong negativ...Read more
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Investigation of C-582 A>G polymorphism at beta globin cluster gene in beta-thalassemia patients
Medical GeneticsThalassemia is the most prevalent monogenic disorder worldwide resulting from the inappropriate production of heme. pati...Read more
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Association study of rs369770942 of neuregulin1 gene 3'UTR with schizophrenia
Medical Genetics: Schizophrenia is a mental disorder and affects approximately 1% of global population. This study suggests that rs36977...Read more
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CRISPR/Cas9-mediated designing of lung adenocarcinoma mouse model by method of knock-in
Medical GeneticsMolecular genetic studies in cell and animal models have evolved our knowledge of discovering causal mechanisms relating...Read more
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Integrin Beta-3 gene polymorphism and risk for myocardial infarction in premature coronary disease
Medical GeneticsContradictory results have been obtained regarding the role of integrin, beta 3 (ITGB3) gene polymorphisms in occurrence...Read more
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Comparative miR34a expression profile analysis in tumor and normal tissues of patients with colorectal cancer
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer is a type of prevalent cancers in populations and allocates numbers of mortality. Recently, researcher...Read more
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Identifying MicroRNA-mRNA regulatory network in breast cancer sample with drug resistance
Cancer; Prevention, Diagnosis and TreatmentA computational approach to prediction of miRNA targets narrowing down potential target sites for experimental validatio...Read more
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microRNAs as potential biomarkers in early detection of Breast cancer
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is one of most worrisome health problems in women across the world. Its incidence and mortality have under...Read more
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Identification of the gene involved in over-production of a novel lipopeptide in an over-expressed mutant of Pseudomonas gingeri
Microbiology and Infectious DiseasesLipopeptides as secondary metabolites, produced by Pseudomonads, can be used as biosurfactants and antimicrobial drugs i...Read more
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Cucurbitacin D from Ecballium elaterium (L.) A. Rich upregulates BCL-2 gene in human gastric cancer cell line AGS
Cancer; Prevention, Diagnosis and TreatmentMedicinal plants are potential sources of new drugs and natural therapies based on them are becoming increasingly import...Read more
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Gene Bookmarking, a way to detect, predict and control molecular processes
Medical GeneticsGene bookmarking is a mechanism of epigenetic memory for gene expression transmission programs, during cell division. ...Read more
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PGD strategy in helping an obligate Hemophilia A carrier woman to have healthy children
Medical GeneticsPreimplantation genetic diagnosis (PGD) is a strategy that has been applied for high-genetic-risk couples with a known g...Read more
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Synthesis and characterization of Gold Nanoparticles by Isolated Bacterial from Kerman Sarcheshmeh Copper Mine Soil and the study of their cytotoxic properties
Nano-Biotech MedicalThe present study was designed to isolate bacterial strain capable of gold nanoparticles (Au NPs) production followed by...Read more
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Simple solution to prevent prostate cancer
Cancer; Prevention, Diagnosis and TreatmentMen above fifty five years old are at high risk for malignant prostate cancer. Currently surgery is the only treatment a...Read more
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Eradication of Cancer Stem Cells through microRNAs: a conceptual view
Cancer; Prevention, Diagnosis and TreatmentmicroRNAs (miRNAs), as 19-24 nucleotides endogenous non-coding RNAs, are involved in the most cellular processes playing...Read more
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Has Clusterin gene a role in spermatogenesis?
Women and Reproductive HealthAzoospermia is a male disorder observed in 1% of the general population and in 10–15% of infertile men that is defined...Read more
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Hepatoprotective effects of magnesium sulfate on pentylenetetrazol-induced seizures in male Wistar rats
Nutrition and HealthMagnesium is the second most abundant cation (after potassium) in the cell and plays an important role in various biolog...Read more
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Progress and Prospect of Nanotechnology in Stem Cells
Nano-Biotech MedicalThe apparition of nanotechnology has paved the way for an obvious understanding of stem cell therapy in vivo and by repe...Read more