niloofar ghobadi
,
Abstracts, [Author]
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Study of gene expression network in varicose veins disease by microarray expression analysis
Medical GeneticsThere is a strong body of circumstantial evidence which implicates genetics in the etiology and pathology of and venous ...Read more
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Evaluation of the HLA-B07 Allelic frequency in the patients with spondyloarthritis syndrome in zanjan province
Medical GeneticsIn 1974 Moll and colleagues established the concept of a group of inter-related disorders originally termed seronegative...Read more
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Thiolated chitosans development and in vitro evaluation of apermeation enhancing oral drug delivery system
Nano-Biotech MedicalThis study investigated the in vitro release of Vancomycin and Amphotericin B fromnovel mocuadhesive chitosan nanofibers...Read more
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Tamoxifen-induced rapid death of GPER positive cell lines by modulating RAS/MAPK signaling pathway
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the most common cancer in women worldwide. Tamoxifen is a nonsteroidal selective estrogen receptor modu...Read more
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Association study of rs369770942 of neuregulin1 gene 3'UTR with schizophrenia
Medical Genetics: Schizophrenia is a mental disorder and affects approximately 1% of global population. This study suggests that rs36977...Read more
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Investigating the role of exon7 axin2 in colorectal cancer (Laboratory and bioinformatics studies)
Cancer; Prevention, Diagnosis and TreatmentIn Iran, colon cancer is the third most common cancer. WNT pathway changes are commonly reported in this cancer. Among t...Read more
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ELISA Cross-Reactivity method to confirm recombinant fliC from salmonella typhimurium and evaluate impurities in purified recombinant protein
Microbiology and Infectious DiseasesRecombinant proteins as important materials for biomedicinal research, need high level of purity in order to be used in ...Read more
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TYCSB culture media reliability for S. mutans isolation
Microbiology and Infectious DiseasesAlthough the clinical significance of dental caries is well recognized, the exact etiology of the condition is not under...Read more
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Application of stem cells in modern therapeutic methods
Stem cell and Medical ApplicationsStem cells are one of the modern therapies being used over recent years to treat diseases such as repairing damaged hear...Read more
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Investigating the antitumor activity of PNU-74654 as Wnt/β-catenin inhibitor, alone or in combination with gemcitabine in MiaPaCa-2 pancreatic cancer cell
Cancer; Prevention, Diagnosis and TreatmentWnt/beta-catenin pathway is one of the key dysregulated pathways in several malignancies, including pancreatic cancer (P...Read more
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The effect of mouse recombinant resistin on blood- brain barrier permeability, MDA content and apoptosis in the early stages of focal cerebral ischemia in a stroke mouse model
Metabolism and Metabolic DiseasesThe aim of this study was to evaluate the dose-dependent effects of mouse recombinant resistin on blood-brain barrier(BB...Read more
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miR-214 induces insulin resistance in C2C12 cell line though targeting Rock1 and Akt2 gene expressions
Metabolism and Metabolic DiseasesMicro-RNAs (miRNAs) are a class of post-transcriptional regulators that play crucial roles in various biological process...Read more
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Structural Study of Lysozyme upon Interaction with Plasmonic gold Nanoparticles
Nano-Biotech MedicalRecent advances in nanotechnology have encouraged scientists to design hybrid systems of nanoparticles and biological ma...Read more
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Apoptotic and cytotoxic effect of the thiosemicarbazone complex with Zn2+ in K562 cell line
Cancer; Prevention, Diagnosis and TreatmentThiosemicarbazone family is organic compounds with antitumor, antibacterial and antiviral effects. In the present stud...Read more
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The Study of the Requested Antibiotics during Each Patient’s confining to Bed in Namazi 1000 beds hospital, May 22nd to July 21st
Microbiology and Infectious DiseasesOccurring resistive microbial trends is one of basic obstacles in infection disease treatments. Prescribing too much ant...Read more
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RNY12 peptidomimetic increases SH-SY5Y Neuronal Survival Comparable to BDNF
Stem cell and Medical ApplicationsBrain-derived neurotrophic factor (BDNF) activates downstream cell signaling pathways through TrkB receptor and triggers...Read more
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Isolation and identification of probiotic bacteria from human milk
Microbiology and Infectious DiseasesBackground: Breast milk is the best nutritional supplement during the first few months of the baby's life. It contains v...Read more
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Molecular monitoring of Chronic Myeloid Leukemia in Chronic Phase (CML-CP)
Medical GeneticsQuantification of the BCR-ABL transcript is recommended to follow-up CML patients that treated by Imatinib mesylate (IM)...Read more
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The Role of Viral Proteins VP24 and VP35 in The Pathogenesis of The Ebola Virus
Microbiology and Infectious DiseasesThe Ebola virus is a member of the Filoviridae family, which is causing hemorrhagic and fatal fever to humans. Ebola is ...Read more
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Osteo therapy and the role of chitosan-alginate in osteoarthritis
Nano-Biotech MedicalOsteoarthritis (OA) is a progressive skeleton disturbance that it is usually related with considerable inability and lim...Read more
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Down regulation of Bcl2 and up regulation of Bax during 2-NDC mediated apoptosis in Acute Promyelocytic Leukemia NB4 cells
Cancer; Prevention, Diagnosis and TreatmentDithiocarbamates have been known as important chemical synthetic compounds for treatment of cancer....Read more
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Effect of DNA Demethylating Agent Genistein on Epigenetic-modifying Estrogen Receptor Alpha Gene Expression and Apoptosis Induction and also Cell Viability in Hepatocellular Carcinoma HepG 2 cell line
Cancer; Prevention, Diagnosis and TreatmentIn the normal mammalian cells, epigenetic changes such as DNA methylation and histone acetylation play an important role...Read more
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Evaluation of the effects of fish oil-derived Eicosapentaenoic acid on the proliferation of colorectal cancer cell line (hct116)
Cancer; Prevention, Diagnosis and Treatmentof these studies have indicated that Eicosapentaenoic acid (EPA) can induce apoptosis and reduce proliferation in cancer...Read more
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Detection of macrolid and fluoroquinolones resistance among campylobacters isolated from diarrhea patients in Markazi province - 2015
Microbiology and Infectious DiseasesCampylobacter species, especially C. jejuni and C. coli, are the most common bacterial causes of gastroenteritis in huma...Read more
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A brief review of regenerative dentistry
Stem cell and Medical ApplicationsTissue regeneration idea has been formed by stem cells identifying and tissue engineering techniques. Stem cells can be ...Read more
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Sensitivity of levofloxacin in combination with ampicillin-sulbactam and tigecycline against multidrug-resistant Acinetobacter baumannii
Microbiology and Infectious DiseasesDuring the last decades, emergence of antibiotic resistance among A. baumannii has been considered as a worldwide alarm....Read more
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Prevalence of septicemia in Intasive care unit and Internal medicine wards patients in Rajaee Hospital of Karaj
Microbiology and Infectious DiseasesSepticemia or blood infections is One of the most important causes of death in patients hospitalized in different parts...Read more
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Effect of genistein associated with agonist (17-β estradiol) on the viability and apoptosis of human hepatocellular carcinoma HepG2 cell line
Cancer; Prevention, Diagnosis and TreatmentBackground: One of the most lethal cancers is Hepatocellular carcinoma (HCC). Genistein (GE) is a choice compound for tr...Read more
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Assessment of energy and water-soluble vitamins intake in the elderly under health care, Isfahan, Iran
Nutrition and HealthThe B vitamins are essential nutrients to maintain nutritionally healthy body. These water soluble vitamins are critical...Read more
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Association of rs699 Polymorphism in AGT Gene with Coronary Heart Disease Risk
Medical GeneticsThe rs699 transition in human angiotensinogen (AGT) gene, result in methionine (M) to threonine (T) substitution at codo...Read more
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Investigating the incidence of cardiovascular in patients with ercutaneous coronary interventionin Bandar Abbas Shahid Mohammadi Hospital
Metabolism and Metabolic DiseasesPCI(Percutaneous coronary intervention) is one of the most common mode of re vascularization. so According to the impo...Read more
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Berberine induced apoptosis of HT-29 cells through mediating of miR-21
Cancer; Prevention, Diagnosis and TreatmentBerberine is an isoquinoline that can be extracted from many medicinal herbs. microRNAs (miRNAs) are small non-coding RN...Read more
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Altered miR-335-5p and miR-124-3p expression in gastric cancer
Medical GeneticsGastric cancer (GC) is fourth most common cancer and third leading cause of cancer mortality worldwide. Considerable eff...Read more
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Eradication of Cancer Stem Cells through microRNAs: a conceptual view
Cancer; Prevention, Diagnosis and TreatmentmicroRNAs (miRNAs), as 19-24 nucleotides endogenous non-coding RNAs, are involved in the most cellular processes playing...Read more
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Recent study about Genetics of Human Obesity
Medical GeneticsObesity has become a global epidemic and contributes to the increasing burden of type 2 diabetes, cardiovascular disease...Read more
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Dietary intake of antioxidants in elderly: A case-control study in Iran
Nutrition and HealthNutrient deficiencies such as antioxidants are common problems in elderly subjects which can result in different cancers...Read more
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Therapeutic effect of Human Tumor Necrosis Factor Receptor-2 on collagen -induced arthritis in Balb/c mice
Metabolism and Metabolic DiseasesRheumatoid arthritis (RA) is a chronic, systemic, immune-mediated inflammatory disease associated with decreased life ex...Read more
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Evaluation of cardiac differentiation potential of menstrual blood- derived stem cells seeded in biocompatible Bombyx mori silk fibroin scaffold in co-culturing with neonatal rat Cardiomyocytes
Stem cell and Medical ApplicationsCardiovascular disorders are leading cause of million deaths each year which reveals the significance of current limitat...Read more
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Determination of physico-chemical properties of Faecalibacterium prausnitzii EVs
Microbiology and Infectious DiseasesFaecalibacterium prausnitzii is one of the most common human gastrointestinal bacteria that has been shown to have sever...Read more
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Hox Genes in Malignant Hematopoiesis in Human- A review
Medical GeneticsHuman beings have 39 HOX genes arranged in four clusters that are located on different chromosomes. These genes are an e...Read more
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The Effect of Vitamin D on Diabetes Mellitus: A Systematic Review
Metabolism and Metabolic Diseases: Diabetes Mellitus is a common metabolic and non-infectious disorder that affects around 346 million people worldwide w...Read more
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Survey of the Relationship between Two Polymorphisms at Position T677C and C1298A in MTHFR Gene with ADHD in Tehran Children
Medical GeneticsAttention deficit hyperactivity disorder is one of the most common behavioral disorders in children, which is associated...Read more
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Evaluation of gonadotropin hormones in non-obstructive azoospermia patients
Women and Reproductive HealthInfertility refers to the inability of couples to achieve a successful pregnancy after a year of sexual intercourse with...Read more
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Comparison of in vitro survival of mononuclear cells derived from B-CLL patients with or without BAFF & APRILL cytokines
Cancer; Prevention, Diagnosis and TreatmentThis article studies the antiapototic effect of cytokines BAFF & APRIL on the survival of mononuclear cells derived ...Read more
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Cancer Stem Cell Therapy Based on Nanostructure Drug Vehicle, PMBN-IL3-GA
Nano-Biotech MedicalTo overcome difficulty of cancer treatment by conventional chemotherapy methods, the targeting drug delivery based on Na...Read more
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Detection of Hepcidin biomarker in plasma of patients with stomach tumor before and after treatment
Cancer; Prevention, Diagnosis and Treatment: cancer is a very important public health problem, which is the main cause of death inindustrialized countries and incr...Read more
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Mortality effect of Silibinin on the A549 cell line
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the leading cause of cancer death in the world, with 1,375,000 deaths annually. Common chemotherapy such ...Read more
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evaluation of anti-mullerian hormone in daughters of women with polycystic ovary syndrome
Women and Reproductive HealthPolycystic Ovary Syndrome(pcos) is one of the most common endocrine diseases among women during their fertility years . ...Read more
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Lantibiotics: New generation of antimicrobial drugs
Microbiology and Infectious DiseasesThese days, due to antibiotic resistance in bacteria, scientists are eager to find new generation drugs. Lantibiotics...Read more
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In silico cancer therapy by using genome editing tool: CRISPR/Cas9
Cancer; Prevention, Diagnosis and TreatmentGiven the fact that cancer today has a broad spectrum of diseases in the populations, and also by relying on the fact th...Read more
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The comparative proteomic pattern study of albumin fraction in type I Gaucher Patients with 2 Dimensional Electrophoresis
Metabolism and Metabolic DiseasesThe gaucher disease is the most common type of lysosomal storage diseases that, particularly affects the macrophage cell...Read more
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Controversy in reports about TNF-α (rs361525) related to susceptibility to Hepatocellular Carcinoma (HCC): a meta-analysis
Cancer; Prevention, Diagnosis and TreatmentTumor necrosis factor-α play a very important role in the development and progression of hepatocellular carcinoma. Pre...Read more
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Matrix metalloprotease-9 (MMP-9) and premature myocardial infarction: A systematic review and meta-analysis
Medical GeneticsCurrent findings on the role of Matrix metalloproteases (MMPs) in cardiac remodelling and the outcome after acute premat...Read more
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conjugation DNA aptamer HER-2 and anti mir-21 as a pharmaceutical agent targeted for apoptosis in MCF7cancer cell line
Cancer; Prevention, Diagnosis and TreatmentIn the past decade, it has become apparent that certain small RNA plays an important role in the initiation, progression...Read more
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A foundation for universal T-cell based adoptive immunotherapy
Cancer; Prevention, Diagnosis and TreatmentThe patient-specific autologous therapy could be a significant limiting factor in the large-scale exploitation of CAR te...Read more
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CRISPR/Cas9-mediated designing of lung adenocarcinoma mouse model by method of knock-in
Medical GeneticsMolecular genetic studies in cell and animal models have evolved our knowledge of discovering causal mechanisms relating...Read more
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Anti-anxiety effects of sinapic acid in NMRI mice
Nutrition and HealthThe present study investigated the anxiolytic effects of sinapic acid on NMRI mice behavior in the elevated plus-maze (E...Read more
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Toxoplasmosis infection in the pregnant women in the first trimester in yasouj city
Women and Reproductive HealthToxoplasmosis is a shared human-animal disease with worldwide distribution caused by Toxoplasma gondii. More than half o...Read more
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MOLECULAR DETECTION OF GUT BACTERIA LACTOBACILLUS, BIFIDOBACTERIA, CLOSTRIDIUM DIFFICILE AND YEAST IN BOWEL DISEASE AND CONTROL PATIENTS
Microbiology and Infectious DiseasesTwo kinds of intestinal disorders included inflammatory bowel disease and irritable bowel syndrome have a strong negativ...Read more
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Self-Concept among Infertile women receiving oocyte donation and Fertile Women
Women and Reproductive HealthOne of the technologies used to assist fertility is oocyte donation. Although there is sufficient information about med...Read more
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Frequency of Escherichia coli O157:H7 among children with and without diarrhea stool samples referred to microbiology laboratory of shahid Madani Hospital in KhorramAbad during 2016-2017.
Microbiology and Infectious DiseasesEscherichia coli serotype O157:H7, which has been recognized as a food-borne pathogen occurring worldwide in the recent ...Read more
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Recombinant fibroin containing the RGD motif enhances limbal mesenchymal stromal cell adhesion and proliferation
Stem cell and Medical ApplicationsAt the periphery of the cornea, in a region called the limbus, exists a population of stromal progenitor cells termed li...Read more
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Antibacterial properties of saffron
Microbiology and Infectious DiseasesSaffron is a small herb of the Welsh family. This is a plant with spherical onions which surrounded by a brown membrane....Read more
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Gene expression profiling of the 8q22-24 position in human breast cancer: TSPYL5, MTDH, ATAD2 and CCNE2 genes are implicated in oncogenesis, while WISP1 and EXT1 genes may predict a risk of metastasis
Cancer; Prevention, Diagnosis and TreatmentGene expression profiling has been suggested to predict breast cancer outcome. The prognostic value of the 8q22 24 posit...Read more
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Characterization of a produced monoclonal antibody against testis antigens on the mouse embryogenesis
Medical GeneticsThe complex series of cellular signaling molecules and transcriptional factors are involved in differentiation and devel...Read more
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Evaluation of Salmonella.spp in Synovial Fluids of Arthritis Patients by Molecular Method
Microbiology and Infectious DiseasesArthritis is an inflammation of the joints. This complication is often accompanied by pain, swelling, stiffness and heat...Read more
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Effect of Zinc Oxide Nanoparticles on expression of proapoptotic BAX and Bcl-2 in Testicular Tissue of NMRI Adult Mice
Nano-Biotech MedicalZinc oxide nanoparticles have numerous applications in medicine and industry. These materials are delivered to the tissu...Read more
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The association between pre-gravid BMI with fasting glucose and lipid profile in gestational diabetes following Assisted Reproduction.
Women and Reproductive HealthGestational diabetes mellitus (GDM) is one of the most endocrine pregnancy outcomes. High prevalence of GDM was reported...Read more
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Intelligent Stimuli Responsive Core@Sell Nanobiomaterial: Biomedical Opportunities and Challenges
Nano-Biotech MedicalNanoscale objects are powerful devices in biotechnology medicine and biomedical sciences. They are potential applicants ...Read more
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Role of NBD and DBD in P- glycoproteinfunction, a Molecular dynamic simulation
Cancer; Prevention, Diagnosis and TreatmentP-glycoprotein (P-gp) is an ATP-binding cassette (ABC) transporter which belongs to multidrug resistance pump super fami...Read more
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Investigation of deaths caused by cancer in Bandar Anzali in 2014
Cancer; Prevention, Diagnosis and TreatmentCancer is one of the main causes of death and disability in Iran and the world. This study was conducted to evaluate the...Read more
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rDKK1 production and purification as an antigen
Cancer; Prevention, Diagnosis and TreatmentA critical goal in prevention and control of cancer is early detection of cancer. It is suggested that the Dickkopf1 (DK...Read more
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Development of a chemiluminometric lateral flow biosensor for sensitive detection of Escherichia coli
Microbiology and Infectious DiseasesPaper based nucleic acid testing (NAT) has attracted significant interest in point of care diagnostic field. Lateral flo...Read more
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Prevalence of beta-lactam resistant isolates of Enterobacteriaceae in clinical specimens
Microbiology and Infectious DiseasesBackground: The emergence of extended-spectrum beta-lactamase (ESBL) producing isolates of Enterobacteriaceae has impor...Read more
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Study of MiRNA-873 expression in Ectopic pregnancy, Endometriosis and Ovarian cancer (review)
Medical GeneticsMicroRNAs are small non-coding RNA molecules that have functions in post-transcriptional regulation of gene expression. ...Read more
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Non-muscle Myosin Heavy Chain 9 Gene (MYH9) Polymorphism (rs4821481) is Associated with Urinary Albumin Excretion in Iranian Diabetic Patients
Medical GeneticsMyosin heavy chain 9 (MYH9) gene polymorphisms have been implicated in a different type of renal disease as well as neph...Read more
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Using micronuclei assay in cancer treatment
Medical GeneticsCancer is one of the leading causes of illness and mortality worldwide, after cardiovascular disease. There are differen...Read more
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Prevalence of Pediculus capitis among School Children in the Eastern Area of Ahvaz, Southwestern Iran
Microbiology and Infectious DiseasesHead lice are wingless, obligate ectoparasites of humans, which affect millions of children worldwide, especially those...Read more
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Evaluation of Adiponectin Hormone in Diabetic and Non-diabetic Patients
Metabolism and Metabolic DiseasesAdipose tissue is currently considered as a hormonally active system in the control of metabolism and not only as a stor...Read more
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Triplet repeats in Androgen receptor and it's relation with cardiovascular disease
Medical GeneticsCardiovascular disease is one of the main cause of death in all around the world and researches indicated that in United...Read more
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Has Clusterin gene a role in spermatogenesis?
Women and Reproductive HealthAzoospermia is a male disorder observed in 1% of the general population and in 10–15% of infertile men that is defined...Read more
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The Approaches for Salivary Glands (SGs) Regeneration: a review
Stem cell and Medical ApplicationsSaliva is secreted from three pairs of major SGs and 100–800 minor SGs and plays a vital role in oral and general heal...Read more
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Designing a Multiplex PCR for Amplification of STR markers linked to DFNB21
Medical GeneticsHearing loss is one of the most common birth defects which can affect about 2 to 3 out of every 1,000 babies born. So fa...Read more
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Induction of apoptosis by silibinin in SKBR3 breast cancer cell line through activation of caspase 3/7
Cancer; Prevention, Diagnosis and TreatmentThe poor prognosis of breast cancer is due to its resistance to the conventional treatments. Therefore, researchers are ...Read more
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Evaluation of cytotoxicity of rainbow trout extracts (Oncorhynchus mykiss) on gastric cancer cell line (AGS)
Cancer; Prevention, Diagnosis and Treatmentrainbow trout due to high levels of essential fatty acids, omega-3 has been identified as one of the important factors i...Read more
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Anthropometric Survey of Worker Population in Bandar-Abbas
Cancer; Prevention, Diagnosis and Treatment1. Background Anthropometry is the science of measurement of body characteristics such as reach, body segment length, ...Read more
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In silico design and analysis of crRNA for post transcriptional regulation of oncogenic miR-128-2 and miR-217 by CRISPR-C2C2 technique.
Medical GeneticsBased on recent studies some microRNAs could have drug resistant effects in turmeric cells during therapy. There are evi...Read more
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The effect of berberin on histone H1 in lung cancer A549
Cancer; Prevention, Diagnosis and TreatmentBerberin, a naturally occurring isoquinoline alkaloid, is present in a number of important medicinal plants. Berberin ha...Read more
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Relation between Resilience and Psychiatric Disorders in Patients with Aids in Bandar Abbas Center for Behavioral Diseases
Nutrition and HealthThe AIDS process is very complex and can significantly affect the physical, social, spiritual and psychological health o...Read more
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Design and evaluation of a colorimetric method for rapid determination of minimal inhibitory concentration of the bacteria belonging to Enterobacteriace
Microbiology and Infectious DiseasesIsolation of antibiotic resistant pathogenic bacteria in clinic may pose the serious problems. So a rapid method capabl...Read more
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Pregnancy management in Iranian Traditional Medicine
Women and Reproductive HealthManaging complications in pregnancy is so important cause of sensitive situation of the mother and the fetus. Physicians...Read more
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Design and expression of an immunogenic construct based on calcium sensing receptor antigen
Cancer; Prevention, Diagnosis and TreatmentDue to texture and small size, identifying the parathyroid from thyroid glands is a very difficult procedure. They shoul...Read more
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The link between Bioinformatics approaches and experimental analysis for microRNA target prediction in non-small cell lung cancer
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the first cancer-related cause of death in the world. MicroRNAs are small non-coding small molecules whic...Read more
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Toxic effects of Selenite and need to bio removal of it
Nutrition and HealthSelenium is an important micronutrient for human and animal health, however it is toxic slightly above homeostatic requi...Read more
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The impact of miR-16 and miR-34a overexpression on the migratory and invasive potential of breast cancer cells
Cancer; Prevention, Diagnosis and TreatmentBreast cancer (BC) is the most frequent type of cancer and a main cause of cancer-related deaths among women worldwide. ...Read more
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Apoptotic effect of anticancer drug Alimta on A549 calls is independent of HMGB1 release
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the leading cause of cancer-related deaths worldwide. Alimta is a new-generation antifolate drug, approv...Read more
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The Study of the Frequency of Antibiotic Usage as an Important Factor in Appearing Antibiotic Resistance in All of the Units in Namazi Hospital
Microbiology and Infectious DiseasesAs the unusual increase in using antibiotics has been suggested as an indicative factor in appearing antibiotic resistan...Read more
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Medicinal plants in the treatment of infertility
Women and Reproductive HealthInfertility is disability of a couple to reach pregnancy for more than one year despite regular sexual intercourse. The ...Read more
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Identification and Cloning of Plasposon Insertion Site in Four Mutants of Pseudomonas Gingeri Deficient in White Line Reaction
Microbiology and Infectious DiseasesAntibiotic resistance is an important concern in the world and also in Iran. Identifying new antimicrobial strategies to...Read more
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the effect of Lactobacillus acidophilus (La) and Lactobacillus rhamnosus (Lr) on proliferation and invasion of Colorectal cancer cells (Caco2).
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer is one of the most common epithelial cancers in the world. Many studies have been conducted on the inh...Read more
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Preparation and optimization of chitosan nanoparticles containing vancomycin
Nano-Biotech MedicalRecently, some novel drug delivery systems were designed to control drug release. The using of polymeric nanoparticles a...Read more
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Examination of mutations in QRDRs in ParC, ParE genes Salmonella Clinical Examples of Zahedan Hospitals
Microbiology and Infectious DiseasesSalmonellosis is a major public health problem worldwide. Although most Salmonella infections result in mild self-limiti...Read more
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Progress and Prospect of Nanotechnology in Stem Cells
Nano-Biotech MedicalThe apparition of nanotechnology has paved the way for an obvious understanding of stem cell therapy in vivo and by repe...Read more
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The role of oils in breast cancer in women (systematic review)
Cancer; Prevention, Diagnosis and TreatmentAbout one-third of cancers may be related to diet, along with lifestyle and physical activity. International data show t...Read more
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The antiproliferative and cell cycle arrest effects of Botox on MCF-7and PC-3 cell line
Cancer; Prevention, Diagnosis and TreatmentBotulinum toxin (Botox) is the most potent biological toxin known to against human life. It can be used as a selective a...Read more
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Evaluation of the effect of saturated and unsaturated fatty acids on the growth and production of outer membrane vesicles in human gut microbiota
Microbiology and Infectious DiseasesA diverse and complex symbiotic microbial community colonize in human host,espicially in the gastrointestinal tract,refe...Read more
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Correlation of umbilical coiling index and HbA1C in gestational diabetes mellitus (one-step strategy).
Metabolism and Metabolic DiseasesGestational diabetes mellitus [GDM] is a prevalent and potentially serious condition which may put mothers and fetuses a...Read more
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Relationship between a phenotype and one gene
Medical GeneticsStudy of whole genomes is genomic. The genes contain instructions for protein synthesis that are the functional part of ...Read more
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Detection of Mycoplasma hyorhinis contamination in biological products by PCR method
Microbiology and Infectious DiseasesMycoplasmas are the major contributors to biological products and cell lines throughout the world and are easily able to...Read more
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Influence of matrix rigidity on the differentiation of mesenchymal stem cells in response to TGF-β
Stem cell and Medical ApplicationsBone marrow human mesenchymal stem cells (hMSCs) are an appreciated cell source for tissue engineering and regenerative ...Read more
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Cytotoxic evaluation of cumin essential oil on breast cancer cell line (MCF-7)
Cancer; Prevention, Diagnosis and TreatmentCancer can be considered as one of the genetic diseases that reduces the mortality rate in cancer cells in this disease....Read more
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Relationship of pre-body mass index with umbilical coiling index in gestational diabetes and non-gestational diabetes mellitus.
Metabolism and Metabolic DiseasesIt has been well documented that overweight or obesity before pregnancy is a strong predictor of gestational diabetes me...Read more
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The effect of Chlorogenic acid on Insulin, GIP and GLP-1 level in healthy humans: A systematic review
Nutrition and HealthAccording to previous studies, there are different supplements in order to prevent and treat diabetes. These studies sho...Read more
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Green synthesis of Silver nanoparticles by Alhagi camelorum gum
Nano-Biotech MedicalSilver nano particles (AgNPs) are used in textiles, cosmetics, tooth brushes, home appliances, food packages and many ot...Read more
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Study the expression rate of claudin-1 gene in Crocus sativus (saffron ) treated AGS cell lines
Cancer; Prevention, Diagnosis and TreatmentClaudins are the main structural and functional proteins of tight junctions in epithelial cells. The altered expression...Read more
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Additive Cytotoxic Effect of Apoptin and Chemotherapeutic Agent Docetaxel on LNCaP Cell Lines
Cancer; Prevention, Diagnosis and TreatmentUnfortunately although chemotherapy is primary therapy for most types of advanced prostate cancer, conventional chemothe...Read more
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Site Directed Mutagenesise of L-Asparagine as an Improveed Anti Cancer Protein with Increased L-ASNase Activity
Cancer; Prevention, Diagnosis and TreatmentL-Asparaginase (L-ASNase) is an FDA approved enzyme which is widely used in fight against acute lymphoblastic leukemia a...Read more
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Stress-induced immobility in male and female rats and its effects on offspring numbers, sex ratios and sexual hormones
Women and Reproductive HealthStress-induced immobility inhibition of reproductive functions and can effect on sexual hormones. Increasing/decreasing ...Read more
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Evaluation of magnesium & copper levels and antioxidant power in serum of women with endometriosis before and after administration of N-acetylcysteine
Women and Reproductive HealthEndometriosis is caused by the presence of ectopic endometrial stromal outside the endometrial cavity. The oxidative str...Read more
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Pharmacogenomics in Multiple sclerosis
Medical GeneticsMultiple sclerosis is a chronic inflammatory disease in the central nervous system. The most effective drugs for MS pat...Read more
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case report of Albinism with pseudo dominant inheritance
Medical GeneticsOculocutaneous albinism type 1 is characterized by hypopigmentation of the skin and hair and the distinctive ocular chan...Read more
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Study of PAX5 gene expression in patients with gastric cancer
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is one of the biggest health problems in the world. Due to the lack of many carcinogenic biomarkers and t...Read more
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An investigation on the structure and function of the cell surface breast-specific antigens for development a new generation of immunotoxins
Cancer; Prevention, Diagnosis and TreatmentBreast cancer with heterogeneous features in morphology, clinic, and responses to therapeutic options, is one of the mos...Read more
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Production and evaluation of scFvs against HER2 antigen for breast cancer immunotherapy
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is common cause of women death in the world. There is ErBb2/HER2 in 25%-30% breast cancer cases. Trastuzu...Read more
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microRNAs as potential biomarkers in early detection of Breast cancer
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is one of most worrisome health problems in women across the world. Its incidence and mortality have under...Read more
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EFFECT OF CHRYSIN NANO-PARTICLES TREATMENT ON ESTROGEN RECEPTORS EXPRESSION LEVELS IN BREAST CANCER CELL LINE
Nano-Biotech MedicalBreast cancer (BC) is increasing in the developing countries. Estrogens are supposed to play roles in BC initiation and ...Read more
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The salivary beta-2microglobulin (β2M) and prostate-specific antigen (PSA) can be used as an alternative to the serum β2M and PSA for diagnosis and monitoring of prostate diseases
Cancer; Prevention, Diagnosis and TreatmentIn recent years, the use of saliva as a specimen, due to its non-invasive and easy access increased. But their roles hav...Read more
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Microencapsulation and double-coating of probiotic bacteria for enhancement of their viability and targeted delivery
Nutrition and HealthThe purpose of this study was to assess the protecting character of double coated beads of alginate-chitosan-Eudragit S1...Read more
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Application of Nanomaterials in cosmetic industry
BeautyUsing nanotechnology in various fields, like electronics, medicine, and now in cosmetics applications has expanded. Glob...Read more
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Association of selenoprotein S expression and its variants with metabolic syndrome in subjects with cardiovascular disease
Metabolism and Metabolic DiseasesSelenoproteins S (SELS or VIMP) may regulate cytokine production, and thus play a key role in the control of the inflamm...Read more
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Frequency of Binding Site at C-Terminal of Helicobacter Pylori CagA Separated from Gastric Tissue Biopsy of Patients with Gastroduodenal Disorders in Shafa Hospital in Khorramabad
Microbiology and Infectious DiseasesHelicobacter pylori (H. pylori) is a gram-negative, microaerophilic bacterium in gastric mucosa. It has a helical shape...Read more
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Effect of Zinc nanoparticle on p53 expression in K562 cell line by Real Time PCR
Medical GeneticsChronic myeloid leukemia is a cancer of blood which is identified by bcr/abl translocation. Imatinib is a tyrosine kinas...Read more
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Effect of different Electromagnetic fields (EMF) on sperm viability and motility
Women and Reproductive HealthToday, due to the advancement of the level of technology, electromagnetic fields (EMS) from various industries affect...Read more
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Epigenetic Mechanisms as Therapeutic Targets
Medical GeneticsEpigenetics, in conjunction with genetic mechanisms, determine the biological fate of cells and living organisms. epig...Read more
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Performing PGD combined with HLA typing on more than 100 blastomeres
Medical GeneticsPreimplantation genetic diagnosis (PGD) is an option for carrier couples who want to assure their child’s health regar...Read more
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Atopic Dermatitis and treatment
Nutrition and Health• diagnostic criteria Atopic dermatitis is difficult to define because of its variable morphology and distribution an...Read more
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Determination of GPR55 overexpression by quantitative real-time PCR as a biomarker for skin SCC detection
Cancer; Prevention, Diagnosis and TreatmentChronic wounds resemble the wounds arising with skin squamous cell carcinoma (SCC). Since they are cancerous, they shoul...Read more
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personalized medicine in oncology
Medical GeneticsThe term peronalized medicine is used for the identification of optimal drug type and optimal drug dosage for individual...Read more
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Normal body mass index as a protective factor for osteoporosis after menopause
Nutrition and HealthIncreased body weight is positively related to higher bone mineral density (BMD) in both pre- and post-menopausal women....Read more
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The effect of Rosa canina extract on Bax gene expression in gastric adenocarcinoma cell line(AGS)
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is the most common cancer in the world. It occurs as a result of many factor and there is massive invest...Read more
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Investigation of mutations and polymorphisms in exon 11, 12, 22 and 23 in Non Caucasian cystic fibrosis patients from the north of Iran
Medical GeneticsCystic fibrosis (CF) is the most common autosomal recessive disease in Caucasians, caused by mutation in cystic fibrosi...Read more
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Nanodispersion-loaded mucoadhesive polymeric inserts for ocular drug delivery: scale up production
Nano-Biotech MedicalFrequent use of highly concentrated solutions may induce toxic side effects and cellular damage at the ocular surface. T...Read more
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Cucurbitacin D from Ecballium elaterium (L.) A. Rich upregulates BCL-2 gene in human gastric cancer cell line AGS
Cancer; Prevention, Diagnosis and TreatmentMedicinal plants are potential sources of new drugs and natural therapies based on them are becoming increasingly import...Read more
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Study of properties of Juglans regia plant on women’s health
Women and Reproductive HealthJuglans regia plant is one of Iranian native plants that some of it’s productive types are in Markazi province. The b...Read more
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studying the effect of silibinin in some of hippo signaling pathway genes , in T47D and MCF7 Breast cancer cell lines with 3D culture.
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is one of the most common malignancy diseases world and is the second leading cause of cancer in women. S...Read more
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Shedding light on new form of combination therapy in acute promyelocyte leukemia
Cancer; Prevention, Diagnosis and TreatmentAlthough physicians have taken a variety approaches for the treatment of acute promyelocytic leukemia (APL), there is no...Read more
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The cultural, ethical and religious challenges of society related to assisted reproductive techniques
Women and Reproductive HealthInfertility is a worldwide problem of high prevalence of reproductive health. Significant advances in assisted reproduc...Read more
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The effect of 5μM benzoquinone on CXCL12 and KITLG genes in mesenchymal stem cells found in bone marrow niche
Stem cell and Medical ApplicationsChronic exposure to benzene is known to damage the BM resulting in development of different types of leukemia. Extrinsi...Read more
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Aloe Vera Herbal Effects on Diabetes Treatment and Prevention: A Systematic Review
Metabolism and Metabolic DiseasesDiabetes is one of the most common metabolic diseases that affects more than 150 million people in the world. It is the ...Read more
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Prevalence of gastric cancer in the patients undergoing bariatric surgery
Cancer; Prevention, Diagnosis and TreatmentIntroduction and goal: The number of obese people has grown up to 1.9 billion worldwide, that a large number of complica...Read more
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The effects of minoxidil on gene expression in the bulb and bulge region of hair follicles by Real time-PCR
BeautyMinoxidil is the most common drug used for treatment androgenic alopecia.Studies have shown that this drug can increase ...Read more
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Therapeutic effects ellagitannin on non communicable diseases
Nutrition and HealthToday, due to the complications caused by the treatment with chemical drugs, the scientists focus on to use of complemen...Read more
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Food Patterns and Framingham Risk Score in Iranian Adults: Tehran Lipid and Glucose Study: 2005-2011
Nutrition and HealthHealthy dietary habits can prevent cardiovascular diseases (CVD). The aim of the present study was to investigate the as...Read more
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Investigation of prevalence class 1 and 2 integron gen in Escherichia coli from Isolated clinical samples Tehran’s hospitals
Microbiology and Infectious DiseasesAs the antibiotics are misused, Integrons are the moving genetic factors which carry resistance gens and have an import...Read more
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The study of Apolipoprotein E4 allele distribution in parents of Down's syndrome children as a risk factor in Iran
Medical GeneticsDown syndrome(DS) is the most common chromosomal abnormality.The most important factor in DS is increased maternal age s...Read more
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Neural System Biomarkers
Stem cell and Medical ApplicationsBiomarkers are widely used by physicians, Labradoreans, and scientists. Popular utilization of biomarkers in vivo and in...Read more
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Evaluation of PRC1 gene expression in gastric cancer patients
Cancer; Prevention, Diagnosis and Treatment: Cancer is one of the most important causes of death. Among cancers, gastric cancer is the fourth most common cancer an...Read more
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Protective effect of silymarin on plasma membrane and DNA integrity of human sperm treated with cadmium chloride
Women and Reproductive HealthCadmium, as an environmental pollutant, exerts its destructive effects on male reproductive system and sperm by inducing...Read more
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Snake venom: an anticancer agent in immunotoxin therapy
Cancer; Prevention, Diagnosis and TreatmentCancer is the second leading cause of death worldwide. Therefore, many studies are underway to innovate more efficient t...Read more
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Antimicrobial susceptibility of Acinetobacter baumannii isolated from different clinical samples in hospitalized patients
Microbiology and Infectious DiseasesAcinetobacter baumannii is a gram negative bacteria, which is cause multidrug-resistant nosocomial infection. Control an...Read more
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The effect of diet in preventing of colorectal cancer: A systematic Review
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer (CRC) is the third most commonly diagnosed cancer in worldwide and it is established that diet has an ...Read more
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Structural Study of Horseradish Peroxidase upon Interaction with Gold Nanoparticles
Nano-Biotech MedicalRemarkable advancements have been made in the field of nanotechnology, including design of hybrid systems of nanoparticl...Read more
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The effects of sodium butyrate on the expression of HDAC8 gene in HT-29 colorectal cancer cell line
Cancer; Prevention, Diagnosis and TreatmentSodium butyrate (NaB) is a potent growth inhibitor and initiates cell differentiation for many cell types in vitro. In t...Read more
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Hydroxyapatite-Gelatin-bone marrow stromal cells construct as an excellent bone graft in animal model
Stem cell and Medical ApplicationsBone healing of critical-sized defects are one of the most challenging orthopaedic problems. In the current study, the e...Read more
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Lack of association between Hypoxia Inducible Factor rs11549465 polymorphism and Preeclampsia
Medical GeneticsPre-eclampsia (PE) is an obstetric disorder that may result inmaternal and neonatal mortality and morbidity. Placental h...Read more
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Finding a new approach for Treatment of osteoporosis with trace element and antioxidant in rat animal model
Metabolism and Metabolic DiseasesOne of the most common bone metabolic and endocrinal disorders is osteoporosis. It is defined by progressive bone loss, ...Read more
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Study on protein of leech saliva of Hirudo Oreintalis, Utevsky & Trontelj 2005 in different ages
Nutrition and HealthMedicinal leech, during feeding, enter in host body many bioactive substances that often contain proteins and peptides. ...Read more
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Discrimination of Leishmania species by Arginine permease gene AAP3as a suitable molecular tool for detection and genetic proximity analysis
Microbiology and Infectious DiseasesLeishmaniasis presents itself in different clinical manifestations such as: visceral Leishmaniasis, Cutaneous Leishmania...Read more
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The Use of Viruses to Treat Cancer
Cancer; Prevention, Diagnosis and TreatmentCancer is an abnormal growth of cells that have lost normal control mechanisms and are able to expand continuously, inva...Read more
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Evaluation and comparison of digestion in two traditional and contemporary medicine schools And its effect on the treatment of diseases
Nutrition and HealthIn traditional medicine, one of the three most important nutritional principles is digestion. In our digestion, we deal ...Read more
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Lack of association between TNF-α rs1800629 polymorphism and Hepatocellular Carcinoma: a meta-analysis
Medical GeneticsTumor necrosis factor a (TNF-α) is a pleiotropic cytokine which can regulate a wide variety of cellular responses. Low ...Read more
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Effect of intracerebroventricular injection of Adenosine on food and fat intake in neonatal chicks
Nutrition and HealthThe present article was aimed to clarify the role of central Adenosine on food intake in neonatal chicks. Adenosine is n...Read more
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In silico evaluation of anti-retroviral effects of lactoferrin from different species
Microbiology and Infectious DiseasesLactoferrin (LF) is an iron binding glycoprotein that is present in body fluids and mucosal secretions. Antimicrobial pr...Read more
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NEW CONCEPTS IN THE IMMUNOPATHOGENESIS OF MULTIPLE SCLEROSIS
Medical GeneticsMultiple sclerosis (MS) is a chronic disorder of the central nervous system characterized by autoimmune inflammation, de...Read more
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Comparison of antimicrobial activity of hydroalcoholic extract of fig(Ficus carica) against Staphylococcus aureus(MSSA & MRSA) with some antibacterial drugs
Microbiology and Infectious DiseasesStaphylococcus aureus is one of the five most common causes of hospital infections and death the worldwide. The excessiv...Read more
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Study of DNA methylation pattern in sf-1 gene promoter region in endometriosis tissue samples of women in north west of Iran
Medical GeneticsEndometriosis is an estrogen-dependent inflammatory disease. Its defining feature is the presence of endometrium-like ti...Read more
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Investigating the toxicity of PEGylated Gold Nanoparticles and red LED light on Ecoli bacteria
Nano-Biotech MedicalToday, the emergence and spread of antibiotic-resistant strains of bacteria have become a major challenge to public heal...Read more
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Survey of Changes gene expression levels of SAP 1-3 Candida albicans samples treated with treated with Fluconazole-loaded PLGA Nanospheres, in comparsion with drug Fluconazole
Microbiology and Infectious DiseasesSecreted Aspartyl Proteinase (SAP) is one of the main virulent factors in the pathogenesis of Candida. This enzyme is en...Read more
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Synergistic effect of berberine and theophylline on apoptosis induction in MDA-MB-231 cells
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the most common type of cancer and a leading cause of cancer mortality among women. Berberine is an iso...Read more
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A review: Runt-related transcription factor 2 (RUNX2) and its signaling pathways in cardiovascular complications.
Metabolism and Metabolic DiseasesVascular calcification (VC) is a process similar to bone mineralization. VC has been observed in chronic kidney disease,...Read more
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Neuroprotective nature of adipokine resistin in the early stages of focal cerebral ischemia in a stroke mouse model
Metabolism and Metabolic DiseasesThe goal of the present study was to test the dose-dependent and time-dependent effects of mouse recombinant resistin in...Read more
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Biological and Molecular Diversity in Telomerase: Characteristics of hTERT in Human, Vertebrates and Yeast
Medical GeneticshTERT (human telomerase reverse transcriptase) is the catalytic subunit of telomerase enzyme, and is essential for its ...Read more
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Investigation the effect of low intensity pulsed ultrasound (LIPUS) on proliferation of G 292 osteosarcoma cells on 3D porous PLGA/β-TCP scaffold within perfusion bioreactor
Stem cell and Medical ApplicationsInvestigation the effect of low intensity pulsed ultrasound (LIPUS) on proliferation of G 292 osteosarcoma cells on 3D p...Read more
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Synergistic Antibacterial Activity of Zinc Oxide Nanoparticles with Cuminum cyminum L. Essential Oil against the Food-Borne Pathogens Salmonella enterica
Nano-Biotech MedicalOne of the ways to control of pathogenic microorganisms in foods is to use preservatives and antimicrobial agents. Diffe...Read more
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Molecular diagnosis of Mycoplasma spp. arthritis by PCR
Microbiology and Infectious DiseasesArthritis is one of the most common inflammatory diseases. It is characterized by symptoms such as systemic inflammation...Read more
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Dendrosomal curcumin nanoformulation modulate apoptosis-related genes and protein expression in hepatocarcinoma cell lines.
Nano-Biotech MedicalIntroduction: The side-effects observed in conventional therapies have made them unpromising in curing Hepatocellular c...Read more
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Tuberculosis is a common HIV infection, control and treatment
Microbiology and Infectious DiseasesPoints out Pulmonary that more than all the be without lymph node, pylorus , Urinary tract , bones and joints , meninge...Read more
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Managing The Abnormal Papsmear In Pregnancy
Cancer; Prevention, Diagnosis and TreatmentCervical cancer is the most common malignancy diagnosed during pregnancy . The incidence of abnormal pap smear in pregna...Read more
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Client's Attitude Towards legal and Ethical Aspects of Sperm Donation in a Health Center of Tehran
Women and Reproductive HealthSperm donation is one of the technologies associated with infertility treatment. Some couples don't have any child due t...Read more
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Autism spectrum disorder (ASD) and cancer: both share same genes but different outcomes.
Medical GeneticsAutism spectrum disorder (ASD) is a neurodevelopmental disorder and it is characterized by social and communication prob...Read more
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Nephroprotective effect of Lavandula officinalis L. ethanolic extract in alloxan induced diabetic rats
Nutrition and HealthDiabetes mellitus (DM), a metabolic disorder is a major public health problem in both developed and developing countries...Read more
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Drafting maggot therapy in personalized cancer therapy
Cancer; Prevention, Diagnosis and TreatmentIn some personalized cancer therapies the elimination of the tumor will be a result of the injection of flesh- eating ba...Read more
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Investigating the absorption of anti-cancer drugs on the surface of the boron nitride nano cage by the dense function theory
Nano-Biotech Medicalmagesterol is a drug used in the treatment of breast and endometrial cancer. Due to the unwanted side effects of this dr...Read more
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BsmI (rs1544410) polymorphism of vitamin D receptor gene modulates improvement of vitamin D status in overweight women with hypovitaminosis D
Nutrition and HealthThe aim of the present study was to evaluate the possible influence of BsmI (rs1544410) polymorphism of vitamin D recept...Read more
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Purification of poly ribosylribotil phosphate capsule from Heamophilus influenza type- b strain ATF2 cultivated in bioreactor
Microbiology and Infectious DiseasesHaemophilus influenzae is a small gram negative cocobacilli non motile and can be seen as pleomorphic. H.inf.can cause ...Read more
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Invitro Effect of Probiotics, Paraprobiotic and Postbiotics of Locally Isolated Lactobacillus casei strains on Colon Cancer Cell Lines
Microbiology and Infectious DiseasesA number of lactic Acid Bacteria (LAB) produce bacteriocin which are bioactive peptides active against a number of path...Read more
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Surface modification of Chitosan nano-fiber by cold atmospheric plasma
Nano-Biotech MedicalSurface modification is the act of modifying the surface of a material by bringing physical, chemical or biological char...Read more
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Enrichment analysis of hsa-miR-320b-1 most related pathways in cancer
Cancer; Prevention, Diagnosis and TreatmentIntroduction: Cancer is a complex disease in which the expression of the gene is unbalanced. MicroRNAs are a group of no...Read more
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A Review of the Fungi Generating the Cellobiose Dehydrogenase Enzyme to Remove Bacterial Biofilms
Microbiology and Infectious DiseasesThe biofilm causes more than 60% of nosocomial infections and 65% human infections. Bacteria in biofilms society are res...Read more
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Comparative investingation of effects of the agricultural pesticides (diazinon and chlorpyrifos) on spermatogenesis in male BALB/c male mice
Nutrition and HealthDiazinon and chlorpyrifos are kind of organophosphate toxins used for agricultural pests. These toxins control acetylch...Read more
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The effect of Thymoquinone on the Cell Cycle and Tumor angiogenesis Process in human breast cancer cell line, MDA-MB-231
Cancer; Prevention, Diagnosis and TreatmentIn recent years, tendency to use phytochemical compounds has been grown dramatically, and more than 25% of drugs used du...Read more
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The effects of vitamin D3 supplement on clinical course of patients with migraine
Nutrition and HealthMigraine is one of the most common headaches all around the world including Iran. Considering that some studies have sho...Read more
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Prevalence of Cysticercus bovis in Cattle slaughter-house in Piranshahr city, Iran (2011-2115))
Microbiology and Infectious DiseasesCysticercus bovis are the intermediate stage in the life cycle of a human tapeworm (Taenia saginata). Cysticercus bovis ...Read more
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Correlation between oral health status and salivary total antioxidant capacity in type 2 diabetes mellitus among Iranian adults
Metabolism and Metabolic DiseasesDiabetes mellitus is a chronic metabolic disease leading to several complications. Among these, dental caries are consid...Read more
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Effect of LPS on regulatory T cell induction in peripheral blood mononuclear cells of endometriosis patients
Women and Reproductive HealthEndometriosis is an estrogen-dependent chronic inflammatory disease affecting women of reproductive age. Regulatory T ce...Read more
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FGF10: Type III Epithelial Mesenchymal Transition and Invasion in Breast Cancer Cell Lines
Cancer; Prevention, Diagnosis and TreatmentMetastasis is one of the important characteristics of a cancer cell. the process called epithelial mesenchymal transitio...Read more
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Biosynthesis of Tellurium nanoparticles by Streptomyces isolate B2.1369F
Nano-Biotech MedicalBiosynthesis of Tellurium nano particles (TNPs) has great advantage since it has no chemical contamination in the enviro...Read more
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Association between the CYP2E1 polymorphisms and CML risk in Iranian population
Medical GeneticsPolymorphism in the genes encoding detoxification enzymes results in variability to metabolize carcinogens and cause int...Read more
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A Turn-Off Fluorescent Sensor Based On Carbon Dots for Sensitive Detection of Tetracycline in Milk
Nutrition and HealthThe detection of tetracycline in animal-derived food and drug is very significant, because of its harmful effects on hum...Read more
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The role of artificial intelligence in medical decisions
Nano-Biotech MedicalThe term "artificial intelligence" was used in 1956. There is still no definitive definition of artificial intelligence ...Read more
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A novel technique to estimate sex ratio in semen
Women and Reproductive HealthOffspring sex is one of the most important factors in controls sex-linked genetically transferred diseases and also for ...Read more
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Study of Effects of Crushed PLGA Nano-fiber Percentage on The Cell Proliferation in Chitosan-Gelatin-βGlycerophosphate Cartilage Scaffold
Nano-Biotech MedicalArticular cartilage has poor reparative capabilities. So Osteoarthritis is widespread globally in almost 70% of people o...Read more
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Investigating the effects of saffron and melatonin with radiotherapy on viability of Hela cells
Cancer; Prevention, Diagnosis and TreatmentCancer is one of the biggest threats to human life. None of cancer treatment have not succeeded completely. One of the n...Read more
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The role of cabergoline medicine in treating Cushing's syndrome: A systematic review
Metabolism and Metabolic DiseasesCushing's syndrome is an endocrine disorder caused by the excessive production of corticosteroid hormones and adrenocort...Read more
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Comprehensive databank of Iranian patients with Noonan syndrome
Medical GeneticsNoonan syndrome (NS) (OMIM 163950) considered as a relatively common (1/1000-2500), developmental, multi-organ and compl...Read more
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Inflammatory markers, vitamin D status and FokI polymorphism of the VDR gene in overweight women
Nutrition and HealthThe present study aimed to evaluate the relationship between inflammatory markers, vitamin D status and FokI polymorphis...Read more
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Removal of Nickel (II) From Drinking Water Using Thiol-Functionalized Chitosan
Nano-Biotech MedicalSome heavy metals are the causes of various diseases among humans. Thus, removing heavy metals is necessary in order to ...Read more
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Relationship between Hypertension in the First Trimester of Pregnancy with Weight and Height at Birth
Women and Reproductive HealthBackground: Hypertensive disorders with a prevalence of %5-10 are among the main causes of morbidity and mortality in mo...Read more
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EXPRESSION OF AN ANTIBODY FRAGMENT (SCFV) AGAINST AMYLOID-BETA USING T7 PROMOTER IN FED-BATCH CULTIVATION MODE
Microbiology and Infectious DiseasesIn the current investigation, the expression yield and solubility of Aβ antibody was analyzed using T7 promoter in fed-...Read more
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In silico epitope prediction and modeling for agent of smallpox and molecular docking for epitope-MHCⅠ receptor
Medical GeneticsAlthough Variola and Vaccinia viruses have been Eradicated but still smallpox can be a serious problem for Societies. H3...Read more
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Evaluation of cytotoxicity, viability and induced oxidative stress by Nickel (II) complex of thiosemicarbazone
Cancer; Prevention, Diagnosis and TreatmentThiosemicarbazones and their metal complexes have significant biological activities including anticancer, antibacterial,...Read more
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Berberine induced cell death of human colon cancer HT-29 through mediating of PARP
Cancer; Prevention, Diagnosis and TreatmentBerberine is an isoquinoline which has many various pharmacological activities, including anticancer activities. Poly (A...Read more
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Molecular screening for E255K mutations in Imatinib Resistant-CML
Medical GeneticsChronic myelogenous leukemia (CML) is a clonal disease that kind of hematopoietic stem-cell cancer. A significant number...Read more
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Evaluation of circulating prognostic tumor marker DNA in the blood of brain tumor patients
Cancer; Prevention, Diagnosis and TreatmentRecent evidence suggests that tumor cells may release DNA into the circulation, which is enriched in the serum and plasm...Read more
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Perineal massage during pregnancy and perineal safety during childbirth
Women and Reproductive HealthIntroduction: Women frequently suffer from perineal trauma during childbirth, especially during the first childbirth. ...Read more
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Identification of Oral strains of Lactobacillus.species in patients with chronic periodontitis and healthy individuals
Microbiology and Infectious DiseasesOral infections constitute some of the most common and costly forms of infections in humans.Chronic periodontitis has be...Read more
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Antiangiogenic Effect of Endostatin-derived Peptides on a Mouse Model of Colon Cancer
Cancer; Prevention, Diagnosis and TreatmentColon Cancer is among the most common malignancies worldwide. Angiogenesis is the formation of new microvasculature thro...Read more
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Silibinin Inhibits miR-17 in Co-cultured HUVECs with A549 Cell Line
Cancer; Prevention, Diagnosis and TreatmentMicroRNAs are involved in different biological processes including cell proliferation and apoptosis, the two intimately ...Read more
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Investigating the relationship between metacognitive beliefs, and premenstrual syndrome and depression caused by that, in female students studying at Tehran University of Medical Sciences
Women and Reproductive HealthThe purpose of this research was studying the relation between meta-cognitive beliefs on premenstrual syndrome and depre...Read more
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Phylogenetic and Bioinformatics analysis of Interferon beta-1 Protein
Medical GeneticsInterferon beta-1b protein is used to improve MS disease and reduce the number of attacks in patients. The purpose of th...Read more
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Comparison of miR-605 expression in normal and tumor tissue samples of patients with colorectal cancer.
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer (CRC) is the third common type of cancer, and is considered as the main cause of cancer deaths in both...Read more
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Investigation of A New Paclitaxel Nano Niosomal formulation and Biological Evaluation of Entrapped Paclitaxel on breast cancer cell line
Nano-Biotech MedicalRegarding that the breast adenocarcinoma is the most widespread disease among women, paclitaxel, an anti-cancer drug, co...Read more
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Doxycycline loaded Kefiran nanofibers: cell viability improvement
Nano-Biotech MedicalDoxycycline (DOXY) is a second generation tetracycline antibiotic with extensive usage. High concentration of DOXY might...Read more
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Determination Of intestinal Escherichia coli Pathotypes Frequency in Tehran Province By PCR
Microbiology and Infectious DiseasesEscherichia coli (E.coli) is an important member of the normal intestinal microflora for mammals, including humans.Diarr...Read more
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Infections Associated with Bacterial Biofilms and Treatment Problems
Microbiology and Infectious DiseasesMicrobial biofilms are seen in 65% of human infections. Bacteria in biofilms society are resistant against antibiotics. ...Read more
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Diet and lifestyle habit imoact on bone density in postmenopausal women
Nutrition and HealthMenopause is the stage of a woman's life, typically between the ages of 45 and 55, when she stops having menstrual perio...Read more
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Comparative miR34a expression profile analysis in tumor and normal tissues of patients with colorectal cancer
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer is a type of prevalent cancers in populations and allocates numbers of mortality. Recently, researcher...Read more
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Ischemia-modified albumin as an oxidative stress biomarker in acute coronary syndrome
Metabolism and Metabolic DiseasesFree radicals increasing or Antioxidants decreasing may contribute to impair the equilibrium between oxidant and antioxi...Read more
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The Evaluation of Methicillin Resistant Staphylococcus aureus (MRSA) Colonization on Skin Lesions in Patients with Psoriasis
Microbiology and Infectious DiseasesPsoriasis is a chronic and inflammatory disease of the skin. Recently, the role of microbial agents in the development o...Read more
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A novel role for stem cells in anxiety disorders treatment
Stem cell and Medical ApplicationsAnxiety disorders are the most common mental disorders which has affected one-eighth of the world's population. Patients...Read more
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Insulin resistance in addicted people: experimental study along with in vitro study and data mining Techniques
Metabolism and Metabolic DiseasesThis study was planned to survey the inflammatory and antioxidant and other Insulin Resistance related condition in addi...Read more
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TThe Biological Effects of Aqueous Extract of Ephedra major on the Development of Balb/C Mouse Embryos 7Th to 10Th Days of Pregnancy
Nutrition and HealthAqueous extract of Ephedra major used as a drug for blood pleasure, sleep disorder and lose weight. But it is effects on...Read more
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Electrospun PVA/PVP/chitosan Membrane with Controlled Release of Antibiotics for intraperiodontal pocket drug delivery
Nano-Biotech MedicalGingivitis and periodontitis have become major public health problem in the world. Such growing incidence of periodontit...Read more
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Effect of Valproic Acid on Proliferation and Apoptosis of Colon Cancer HT 29 Cell Line
Cancer; Prevention, Diagnosis and TreatmentThe structure of chromatin is made up of DNA, histones, and non-histone proteins with the basic repeating unit, nucleoso...Read more
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Effect of Hypiran on the oxidative stress responses in experimental autoimmune encephalomyelitis
Nutrition and HealthExperimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis. The hallmark of this disease i...Read more
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Explaining Women's Views on Cervical Cancer: A Qualitative Study
Cancer; Prevention, Diagnosis and TreatmentCervical cancer is the second most common cancer in the world , Which, if detected and treated at early stages, is almo...Read more
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Development and implementation of a novel panel consisting 16 STR markers linked to the HLA-gene-cluster applicable for HLA-typing, PND&PGD
Medical GeneticsPGD (Pre-implantation Genetic Diagnosis) in combination with human leukocyte antigen (HLA) matching, allow not only sele...Read more
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Effect of hemodialysis on antioxidant enzyme levels in non- diabetic dialysis patients
Metabolism and Metabolic DiseasesDialysis patients are at a high risk for oxidative stress, resulting in an imbalance between the formation of free radic...Read more
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Microfluidic 3D cell-Culture platforms for drug response monitoring: potential applications for individualized cancer treatment
Cancer; Prevention, Diagnosis and TreatmentIndividualized monitoring of drug response is supposed as a main constituent of personalized treatment. Current methods ...Read more
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Nano ironoxide effects on mouse heart development; a genome wide mRNA level study
Nano-Biotech MedicalNanoparticles have been used for clinical applications such as Hyperthermia, increasing the resolution of magnetic reson...Read more
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Effect of folic acid supplementation on acute effects of trimethoprim/sulfamethoxazole on histopathological changes in the testes of adult male rats
Stem cell and Medical ApplicationsMale infertility has been reported following long-term sulfasalazine use for ulcerative colitis treatment. However, the ...Read more
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An in vitro study on the cytotoxicity of anticancer drug Mitoxantrone on hematopoietic stem cells of bone marrow
Cancer; Prevention, Diagnosis and TreatmentMitoxantrone (Novantrone®; dihydroxyanthracenedione) is a synthetically designed antineoplastic agent and structurally ...Read more
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The Role of Nanobiotechnology in Identification and Treatment Lung Cancer
Nano-Biotech MedicalNanotechnology is the engineering of functional systems at the molecular scale. Therefore, it is possible to combine nan...Read more
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Production of recombinant Streptococcal pyogenes exotoxin a protein
Medical GeneticsExotoxin A is one of the toxins which produce by group a streptococcuses. This Toxin is a protein soluble substance whic...Read more
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The effects of methanolic soy extract on ovary tissue modification in model of polycystic ovary syndrome as an inflammation state
Women and Reproductive HealthIntroduction and Objective: Chronic low-grade subclinical inflammation has been increasingly recognized as an interposer...Read more
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A simple way for extracting singular porphyrin peaks from total fluorescence spectrum of plasma
Metabolism and Metabolic DiseasesPorphyrins are organic compounds formed from the breakdown of hemoglobin. Any disturbance in porphyrins’ level can be ...Read more
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Anticancer effect of Quercus infectoria aqueous leaf extracts against colon cancer HT29 cell line
Cancer; Prevention, Diagnosis and TreatmentIn traditional medicine and previous studies, Quercus infectoria plants are a well-known and have been suggested as a ca...Read more
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Cloning of Human THAP11 Gene in Lentiviral Vector
Stem cell and Medical ApplicationsThap11, the most recent described member of THAP domain family, which is in volved in cell proliferation and described a...Read more
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Investigating th expression of E-cadherin gen among patients suffering from stomach cancer in West Azerbaijan province
Medical GeneticsGastritis Cancer is one of the general death causes of cancer all over the world. According to the results of the resea...Read more
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Can air pollution impact of sperm parameters? A meta- analysis
Women and Reproductive HealthAir pollution is common in all countries and affects reproductive functions in men and women. It particularly impacts sp...Read more
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The association of the H19 rs217727 polymorphism and Preeclampsia
Medical GeneticsPre-eclampsia is a pregnancy specific disorder; which is defined as pregnancy-induced hypertension and proteinuria. H19 ...Read more
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Association between Biochemical Markers BHCG in Screening First Trimester of Pregnancy in Women with PCOS
Women and Reproductive HealthPCOS (polycystic ovary syndrome) is a common endocrine system disease among women of reproductive age. Its prevalence in...Read more
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Human reovirus destroys liver cancer cell line (Huh-7)
Cancer; Prevention, Diagnosis and TreatmentThe Huh-7 cell line was derived from a liver tumor in a 57-year-old Japanese male patient in 1982. Hepatocellular carcin...Read more
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THE TOLE OF PROBIOTICS IN PUBLIC HEALTH
Nutrition and HealthIn the last decade, we have seen dramatic changes in understanding the role of foods in improving human health. scientif...Read more
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analysis of circulating mir-141, and mir-375 in small cell lung cancer patients
Medical Geneticslung cancer is the main cause of mortality from cancer in the world. small cell lung cancer is the most invasive lung ca...Read more
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Gene Editing: As a new treatment for HIV
Medical GeneticsCurrent treatments in HIV treatment don’t eliminate the low level of viral replication in latently infected cells, whi...Read more
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A genetic variant in Multiple drug resistance gene is associated with poor prognosis of patients with esophageal squamous cell carcinoma
Cancer; Prevention, Diagnosis and TreatmentEsophageal squamous cell carcinoma (ESCC) is one of the causes of death from cancer. Several genetic variants in the 7q2...Read more
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Effect of letrozole as alternative aromatase inhibitor on development of ovarian follicles and uterine changes in adult NMRI mice strain and their infants
Microbiology and Infectious DiseasesLetrozole is used as an aromatase inhibitor, to increase ovulation induction. This drug is usually prescribed for patien...Read more
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Evaluation of NTT and Double-Test in screening of Down Syndrome
Women and Reproductive HealthPrenatal diagnosis of genetic, congenital and hereditary diseases is the first step to prevent and control these prob...Read more
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Study of matrix metallo proteinase (MMP)-9 gene & its phylogeny tree as a critical gene in metastases
Medical GeneticsThere has been a clear connection between MMPs,ECM degradation & cancer cell invasion. Matrix metalloproteinase(MMP)-9, ...Read more
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Motor neuron differentiation potential of human umbilical cord blood- derived mesenchymal stem cells, in vitro
Stem cell and Medical ApplicationsMany people suffer from spinal cord injuries annually. These deficits usually threaten the quality of life of patients. ...Read more
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A study on the interaction of angiotensin I converting enzyme inhibitory peptide with human hemoglobin protein by conductometry method in the absence and presence of a low frequency electromagnetic fi
Metabolism and Metabolic DiseasesHigh blood pressure, or hypertension, is a chronic disease in which the blood pressure goes up. Angiotensin converting e...Read more
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Overexpression of cancer stem cell protein, Piwil2, promotes the expression of anti-apoptotic and proliferative genes in the gastric cancer cell line MKN-45
Cancer; Prevention, Diagnosis and TreatmentPiwi-like RNA-mediated gene silencing 2 (Piwil2) is an oncogene that is highly expressed in different tumors including ...Read more
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Survaey polymorphism rs 866751883 ADAM2 gene infertile men referred to infertility treatment centers in East Azerbaijan which under treatment with IUI (Intrauterine Insemination)
Medical GeneticsOne of the most important genes in human infertility is ADAM2 gene. The gene function is the important in the process of...Read more
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Function of Diabetes Mellitus on the Body, Diagnosis until Treatment
Medical GeneticsDiabetes mellitus is a metabolic pathway in which the insulin hormone is secreted or incompletely secreted; it is a meta...Read more
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Effects of 5-aza-2ˈ-deoxycytidine and Valproic Acid on Epigenetic-modifying DNMT1 Gene Expression, Cell Growth Inhibition and Apoptosis Induction in Hepatocellular Carcinoma WCH-17 cell line
Cancer; Prevention, Diagnosis and TreatmentIntroduction DNA molecule of the eukaryotic cells is found in the form of a nucleoprotein complex named chromatin....Read more
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MYH9 gene and urinary albumin excretion in Iranian diabetic patients
Medical GeneticsDiabetic nephropathy (DN) is one of the most common causes of end stage renal disease (ESRD).: Myosin heavy chain 9 (MYH...Read more
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Evaluating Anticancer Effects of Tamarix ramosissima on A549 Cells
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the leading cause of cancer death all over the world. Using plant derived materials as folk remedy has be...Read more
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Genetic variations of Cholesteryl ester transfer protein and diet interactions in relation to lipid profiles and coronary heart disease: A systematic review
Nutrition and HealthThe number of investigations on diet–genotype interactions in the prevention or treatment of dyslipidemia have increas...Read more
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Effect of marjoram extract on sperm concentration and its survival percentage in oxidative-cadmium stress in adult male rats
Nutrition and HealthNutrition Safety and Health is one of the important factors in fertility.Cadmium as an environmental pollutant by free r...Read more
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The role of long non-coding RNAs in hematologic malignancies
Cancer; Prevention, Diagnosis and TreatmentLong noncoding RNAs(lncRNAs) are a novel heterogeneous group which refer to non-coding RNA molecule ranging in length fr...Read more
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study of promoter methylation status of pax5 gene in patients with gastric cancer
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is the fifth leading cause of cancer and is also the third leading cause of death in the world .Although ...Read more
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Identification of Gardenerla vaginallis in urine samples of patients with Urinary Tract Infeetion by polymerase chain reaction(PCR) techniques
Microbiology and Infectious DiseasesUrinary tract infection(UTI) is the most common infection and also the second common infection in human societies. Annua...Read more
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Molecular markers in the diagnosis of lung cancer
Cancer; Prevention, Diagnosis and Treatmentlung cancer is the leading cause of cancer-related mortality, one of the main causes of mortality by 2010. There are sev...Read more
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The effects of anticancer of 7-hydroxycoumarine on the colon cancer cell line (HT29) and the normal mouse fibroblast cells (L929)
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer it is a lethal and common cancer. due to the development of drug resistance to chemical drugs, the ne...Read more
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Fast detection of Pseudomonas aeruginosa keratitis by Polymerase Chain Reaction (PCR)
Microbiology and Infectious DiseasesPseudomonas aeruginosa is an opportunistic pathogen that has different virulence factors. This organism is commonly foun...Read more
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Serum levels of testosterone, dehydroupiandrosterone sulfate, luteinizing hormone and follicular stimulus hormones in offspring of women with polycystic ovary syndrome
Women and Reproductive HealthPolycystic Ovary Syndrome(pcos) is one of the most common endocrine diseases among women during their fertility years . ...Read more
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The effect of curcumin, zinc and N-acetylcysteine on the MMP9 expression
Metabolism and Metabolic DiseasesCardiovascular diseases (CVD) are mostly prevalent in the general population.Matrix metalloprotease 9 (MMP9) is a matrix...Read more
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study of microbial quality of some food samples
Nutrition and Healthbacterias are considered as the most important factor to cause infection and food poisoning ,so that microbial contamina...Read more
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HETEROGENEITY OF ESCHERICHIA COLI ISOLATES WITHIN DIFFERENT
Microbiology and Infectious DiseasesAim:Escherichia coli is one of the most important bacterial pathogens causing urinary tract infections (UTIs) . This bac...Read more
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Determination of antibiotic-resistant strains of isolated Brucella in Markazi Province
Microbiology and Infectious DiseasesBrucellosis is one of the common diseases of man and animals are caused by bacteria of the genus Brucella. The purpose o...Read more
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Green synthesis of Gold nanoparticles by water extract of common nettle leaves
Nano-Biotech MedicalGold nano particles (AuNPs) are being considered for cancer treatments for targeted drug delivery in pharmacology and me...Read more
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Identifying MicroRNA-mRNA regulatory network in breast cancer sample with drug resistance
Cancer; Prevention, Diagnosis and TreatmentA computational approach to prediction of miRNA targets narrowing down potential target sites for experimental validatio...Read more
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Effect of Extract of Origanum Vulgare on the activity of alanine aminotransferase enzyme in healthy and diabetic mice
Metabolism and Metabolic DiseasesWild Thyme is a great medicinal plant that grows in different areas of the Mediterranean and some parts of Asia.Present ...Read more
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study of mesenchymal stem cell differentiation to chondrocyte on electrospun nanofibrous polyvinyl alcohol alginate sulfat blend
Stem cell and Medical ApplicationsCartilage tissue engineering is used as a potential solution for replacing or repairing damaged tissue. In this method, ...Read more
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Diagnosis of Cytomegalovirus in Sinusitis by Molecular method
Microbiology and Infectious DiseasesCytomegalovirus is one of the important viruses that can cause a wide range of diseases in humans. Sinusitis is a common...Read more
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Characterization of a carboxypeptidase inhibitor peptide isolated from Iranian scorpion venom glands cDNA library: a good candidate for cancer therapy
Cancer; Prevention, Diagnosis and TreatmentFinding a safe strategy for targeting tumor cells without affecting normal cells is one of the goals of cancer treatment...Read more
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Omega-3 and its effects on colorectal cancer
Cancer; Prevention, Diagnosis and TreatmentCancer as the second leading cause of death has always been a threat to human life and due to its peculiar nature and la...Read more
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Determining the Interactions between Major Dietary Patterns and LRP5 Genotypes (rs556442) on Bone Discordance in Postmenopausal Women Referred to Shariati Hospital
Nutrition and HealthOne of the challenges in the diagnosis of osteoporosis is bone discordance. Many studies have confirmed an association ...Read more
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Cloning, expression and functional assay of bacterial Uricase, a medical enzyme for the treatment of chronic gout
Metabolism and Metabolic DiseasesUricase, which is originated from a variety of organisms including bacteria, is an important agent for tracing of Uric A...Read more
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Evaluation of nitrosative stress in sprayer workers
Metabolism and Metabolic DiseasesAgricultural pesticides have an important impact on human health and farmers are people who are more exposed to pesticid...Read more
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Crispr/cas9 a New Approach to Genome Engineering
Medical GeneticsIn 1987, scientists found an acquired immune system in E.coli genome, included series of short repetitive interspaced pa...Read more
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Anti-clostridial role of probiotics in prevention and treatment of Clostridium difficile infections
Microbiology and Infectious DiseasesPatients with varied conditions, such as Antibacterial therapy, Cancer chemotherapy, and gastrointestinal surgery are at...Read more
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Mesenchymal stem cells enhance the metastasis of cervical cancer cell line, CaSki, in 3D cell culture system
Cancer; Prevention, Diagnosis and TreatmentMesenchymal stem cells, also known as mesenchymal stromal cells (MSCs), are attractive for repair and regeneration of ti...Read more
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Effect of Velcade in Combination with Nanocurcumin in Breast Cancer 4T1
Nano-Biotech Medical: It is well known that breast cancer has the highest incidence rates of about 30% of all types of cancer in women, and ...Read more
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Antioxidants as DNA protective compounds
Nutrition and HealthBased on the recent findings, antioxidants are some essential factors that can have major role on the health. The human...Read more
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Design and cloning of tanatin peptide in Pichia.pastoris and evaluation of its antifungal activity
Microbiology and Infectious DiseasesNowadays, control of fungal infections is one of the most important goals in the field of health. Therefore, developing ...Read more
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Investigation of cytotoxicity, cell cycle and induction of apoptosis by methyl-thiosemicarbazone complex with Cu2+ in K562 cell line
Cancer; Prevention, Diagnosis and TreatmentThiosemicarbazone compounds have previously been considered as a new series of potent apoptosis-inducing agents. In the ...Read more
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Investigation of Infectious Causes of Infertility by Molecular Detection of Mycoplasma hominis in Men's Semen
Microbiology and Infectious DiseasesSince infectious agents are among the important causes of infertility, we decided to identify Mycoplasma hominis in the...Read more
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Investigation of KLF1 gene and It's affection on thalassemia minor patients
Medical Genetics: Thalassemia is a type of hereditary autosomal recessive disorder in which the existing genetic defect reduce the amoun...Read more
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Investigation of Lead and Chromium Elements in Female Patients with Breast Cancer Before and After Chemotherapy
Cancer; Prevention, Diagnosis and TreatmentHeavy metals such as lead and chromium can be in various forms, including free ions, metal compounds or carcinogenic par...Read more
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Gene Bookmarking, a way to detect, predict and control molecular processes
Medical GeneticsGene bookmarking is a mechanism of epigenetic memory for gene expression transmission programs, during cell division. ...Read more
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Expression of CD74 in Ovarian cancer
Medical GeneticsOvarian cancer is a cancer that forms in or on an ovary. The pro-inflammatory cytokine migration inhibitory factor (MIF)...Read more
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Evahuation of Serum Cholesterol as a Component Of Metabolic Syndrome in the Cord Blood of Mothers With Polycystic Ovary Syndrome
Women and Reproductive HealthPolycystic ovary syndrome is one of the most common endocrine disorder among women of reproductive age is the prevalence...Read more
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Marine Biotechnology in public health and food safety
Nutrition and HealthSea and oceans make up more than 70 percent of the Earth's surface, and on the other hand, more than 80 percent of livin...Read more
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Interaction of Methotrexate on Stability and structure of Human Serum Albumin
Nano-Biotech MedicalHuman serum albumin(HSA) as the most abundant carrier protein in blood plasma has been widely studied. HSA is often used...Read more
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Blocking of vascular endothelial growth factor signaling through design of bi-specific single domain antibody
Nano-Biotech MedicalOver-expression of vascular endothelial growth factor (VEGF) leads to the proliferation and neovasculature of cancer cel...Read more
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Improvement of Prognostic model for breast cancer recurrence by data mining methods
Cancer; Prevention, Diagnosis and TreatmentIn Iran, every year 10,000 people suffer from breast cancer, of which half of them are under the age of 50. The recurren...Read more
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The prevalence of adeABC encoding genes among Acinetobacter baumannii carbapenem resistant clinical isolates.
Microbiology and Infectious DiseasesAcinetobacter baumannii is the important cause of nosocomial infections worldwide due to its propensity to rapidly acq...Read more
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The efficacy of Leptin on physical and psychological stress causing gastric ulcer: Participations of nitric oxide and prostaglandin E2
Nutrition and HealthThe present study aimed to assess the effects of Leptin on physical and psychological stresses inducing gastric ulcer. T...Read more
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Association of Cytochrome P450 2C19 (CYP2C19) gene polymorphism and the risk of endometriosis in Iranian population
Women and Reproductive HealthEndometriosis is a chronic disease that is characterized by the occurrence of endometrial glands and stroma outside the ...Read more
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An update review about stem cell therapy for diabetes mellitus
Stem cell and Medical ApplicationsMesenchymal stem cells (MSCs) are the most widely used stem cells of the human body because of successful isolation, and...Read more
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Influence of CYP2D6 and CYP3A4 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia and treatment response
Cancer; Prevention, Diagnosis and TreatmentXenobiotic- metabolizing enzymes compose an important line of defence against a variety of carcinogenes and environmenta...Read more
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BRCC2 gene inhibits lung cancer cell proliferation and invasiveness in vitro and in vivo:Prospect for gene therapy
Cancer; Prevention, Diagnosis and TreatmentLung cancer is one of the major causes of cancer related death worldwide .Despite recent improvements, resistance to con...Read more
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COMPARATIVE STUDY OF OLERACEIN E AND OLERACEIN L EFFECTS ON ANTI OXIDANT ACTIVITY, ANTI DIABETIC INDICATORS AND DAMAGE BIOMARKERS LEVELS IN PANCREATIC CELL LINE
Nutrition and HealthThe medicinal plants have valuable biochemical effects. The aim of this study was to assess the effects of Oleracein E a...Read more
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Comparison of Antibacterial Activity of Essential Oil of Varieties of Calendula Plant from Varamin (Iran) on Escherichia coli and Staphylococcus aureus
Microbiology and Infectious DiseasesUncontrolled use of conventional antibiotics and synthetic antibacterial medicine has led to the proliferation of microb...Read more
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Biosynthesis of Gold nanoparticles by Areca palm fruit extract
Nano-Biotech MedicalTargeted drug delivery by Gold nano particles (AuNPs) is a new era in pharmaceutical research; i.e. curing tumoral cance...Read more
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Evaluation of nitrate and nitrite content in meat and meat products and their role of these substances in carcinogenesis
Cancer; Prevention, Diagnosis and TreatmentBecause of N-nitrous compounds formation in meat and meat products, There is a direct correlation between high consumpt...Read more
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Genetic Diversity and Phylogenetic Analysis of the Iranian Leishmania Parasites Based on HSP70 Gene PCR-RFLP and Sequence Analysis
Microbiology and Infectious DiseasesDespite the broad distribution of leishmaniasis among Iranians and animals across the country, little is known about the...Read more
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Investigation of toxicity effect of 4-Mepgc and 4-No2pgc on the K562 cell line (chronic myeloid leukaemia)
Cancer; Prevention, Diagnosis and TreatmentLeukemia is a particular type of cancer characterized by the failure of cell death or disability in the differentiation ...Read more
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Assessment of Tuberculous arthritis using molecular technique
Microbiology and Infectious DiseasesBacterial arthritis is one of the arthritis diseases known that can rapidly cause joint damage. Among the bacteria caus...Read more
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Interaction of an anti-cancer drug Crizotinib with serum albumin: A docking study
Cancer; Prevention, Diagnosis and TreatmentCancer treatment is one of the major challenges of medical science today. Among them, lung cancer is a common type of ca...Read more
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Assessment of the dietary intake of Vitamin D and Blood pressure in Elderlies with health care
Nutrition and HealthPopulation studies have demonstrated that there is an inverse association between dietary intake of vitamin D and incide...Read more
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Alterations of gyrA in Enterobacteriaceae isolated of urinary tract infection resistance to quinolones antibiotics
Microbiology and Infectious DiseasesUrinary tract infection is one of the most common infections, which if not treated, it can be cause seriouse problem in ...Read more
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Study of DNA binding and cytotoxic activity of a benzochromene derivative
Cancer; Prevention, Diagnosis and TreatmentDNA is currently a target for some of the drugs used in cancer therapy. Among the various treatment strategies for remov...Read more
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The effects of specific expression of Apoptin under control of PSES and PSA promoter on apoptosis of LNCaP cells
Cancer; Prevention, Diagnosis and TreatmentApoptotic effects of viral protein Apoptin has been demonstrated in numerous studies. However, its tumor specificity has...Read more
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Frequency of TEM and SHV genes in the strains of Acinetobacter producing broad-spectrum isolated ß-lactamases from Zahedan patients by PCR method
Microbiology and Infectious DiseasesAcinetobacter baumannii is one of the most important factors in hospital infections, and its Colonization rate in hospit...Read more
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Microfluidic Nanocomplex-Based Localized Gene Delivery Platform for Bone Tissue Engineering.
Stem cell and Medical ApplicationsAnnually more than 2.2million bone graft procedures take place in worldwide. Biomaterials-based bone tissue engineering ...Read more
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Polymorphisms evaluation of the thiopurine S-methyltransferase gene among the Iranian acute lymphoblastic leukemia population
Medical GeneticsThiopurine S-methyltransferase (TPMT) is a cytosolic enzyme which catalyzing the S-methylation of 6-mercaptopurine and...Read more
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Cloning and expressing the chimeric peptide lactoferricin-lactoferampin camel in Lactococcus lactis for promising as a candidate for oral medication
Nutrition and HealthLactococcus lactis is known as probiotics due to its lack of harmful toxins. Because of its high growth potential and re...Read more
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Treatment of vitamin D deficiency in pregnancy
Women and Reproductive HealthThe purpose of this study is the importance of Vitamin D in pregnancy and its treatment. Serum levels of Vitamin D in th...Read more
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Rosmarinic acid, a Anti-glycation agent, inhibits protein glycation in vitro
Metabolism and Metabolic DiseasesDiabetes mellitus is one of the most non-communicable diseases and is the fifth leading causes of death in most of the d...Read more
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Down-Regulation of Bcl-2 and Mcl-1 by MiRNA-15 and 16 Synergistically Enhances the Apoptotic Effects of ABT-199 and Fludarabin in CLL Cells
Cancer; Prevention, Diagnosis and TreatmentMiRNA-15 and 16 can act as a tumor suppressor gene by interfering with Bcl-2 and mcl-1. Studies have demonstrated that o...Read more
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Some candidate Biomaterials for Amniotic Membranes (AM) Regeneration: a review
Stem cell and Medical ApplicationsAmniotic Membranes (AM) wich form the amniotic sac filled by amniotic fluid and completely surrounds the embryo/fetus. I...Read more
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Easy and efficient purification of flagellin from salmonella typhimurium ATCC 14028 without necessity of ultracentrifugation
Microbiology and Infectious DiseasesGram negative bacteria's Flagellin has many applications in diagnosis, treatment and vaccines. fliC, the major protein o...Read more
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Bioinformatics evaluation of hsa-miR-548g related to single nucleotide polymorphism (rs1803622) of GAPDH gene in patients suffering from breast cancer
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is one of the most prevailing cancer among females. GAPDH gene is located on chromosome l on position of G...Read more
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Studying the relation of blood lead level with the thyroid hormones and blood factors
Metabolism and Metabolic DiseasesLead has many applications in the industry but does not play a specific physiological role in the body. According to per...Read more
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Canavan disease: clinical and molecular review
Medical GeneticsCanavan disease is a rare autosomal recessive disorder that predominantly affects the central nervous system with white ...Read more
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Combination of ultrasonic waves and dynamic shear stress by design of a novel perfusion bioreactor for 3D bone tissue engineering
Stem cell and Medical ApplicationsIt is shown that mechanical loading by ultrasound enhanced cell proliferation and differentiation. The aim of present st...Read more
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Cell-Penetrating Peptides and Tumor Targeting Peptides: achievements and challenges in application for cancer treatment
Cancer; Prevention, Diagnosis and TreatmentDespite significant advancement in the anti-cancer drugs recently, cancer still remains one of the leading causes of dea...Read more
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Evaluating the genetic variations of ARPT1 gene in infertile men with abnormality in sperm head morphology referring to Royan institute.
Medical GeneticsThe evaluation of human sperm morphology is a controversial aspect of the semen analysis for the determination of male...Read more
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The effect of aerobic training with pomegranate juice on glycemic control and lipid profile women with type 2 diabetes
Metabolism and Metabolic DiseasesType 2 diabetes is a common metabolic disease, which is associated with obesity and immobility. The studies have shown t...Read more
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Evaluation of Interleukin 10 Gene Promoter Polymorphisms of -592A/C and -1082A/G Region Among Obese Individuals with Type 2 Diabetes in Alborz Province
Metabolism and Metabolic DiseasesToday diabetes is one of the most prevalent noncontagious diseases around the world. There is strong evidence showing in...Read more
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Gankyrin expression in ovarian cancer and its correlation with clinicopathological parameters
Cancer; Prevention, Diagnosis and TreatmentGankyrin (p28GANK) is a novel oncoprotein which regulates the phosphorylation of retinoblastoma protein (pRb) and degrad...Read more
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Evaluation of cytotoxicity of aqueous-ethanolic extract of pineapple on ovarian cancer cells (A2780 cell line)
Cancer; Prevention, Diagnosis and TreatmentToday, the global trend towards the use of herbal medicines for treating diseases has tended, while developed countries ...Read more
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Biosynthesis of Silver nanoparticles using water extract of Ziziphus spina_cheristi Leaves
Nano-Biotech MedicalSilver nanoparticles (AgNPs) have been widely used as an antiseptic against a wide range of microorganisms. The goal of ...Read more
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Application of cold atmospheric plasma in human and veterinary medicine
Microbiology and Infectious DiseasesIn the last few years plasma medicine has completed the transition from a field of research to actual evidence-based cli...Read more
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Effect of Praziquantel Drug on Prevention of Afflicting Dogs with Cestode Echinococcus Granulosus
Microbiology and Infectious DiseasesAwareness of the impact range of praziquantel drug on prevention of afflicting dogs with echinococcus granulosus parasit...Read more
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Anti-inflammatory activity of Caspian Cobra (Naja naja oxiana) snake Venom in EAE model of MS
Medical GeneticsMultiple sclerosis (MS) is a chronic neuroinflammatory demyelinating disorder of the Central Nervous System (CNS) with a...Read more
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The relationship between serum creatinine and creatinine clearance with the occurrence and severity of coronary artery disease
Metabolism and Metabolic DiseasesCardiovascular diseases are thought to be the most important reason of mortality around the world. Among them coronary a...Read more
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Genes involved into both alternative splicing and aging pathways as biomarkers for Parkinson Disease diagnosis
Medical GeneticsParkinson's Disease is a degenerative movement disorder that exhibit symptoms through progressive loss of dopaminergic...Read more
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Antibacterial effects of curcumin encapsulated in micelle nanoparticles on mexX gene expression in ciprofloxacin resistant isolates of Pseudomonas aeruginosa in Guilan
Nano-Biotech MedicalCurcumin, a polyphenolic compound fromturmeric (Curcuma longa) is a pharmacologically safe agent that has antibacterial ...Read more
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The role of natural antioxidants in treatment of cancer
Cancer; Prevention, Diagnosis and TreatmentCancer is one of the most common causes of death in advanced industrial societies. With the prevalence and spread of can...Read more
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Development of an Antagonistic TGF-β by Directed Blocking of its TβRI Binding Site to Inhibition TGF-β Signaling
Cancer; Prevention, Diagnosis and TreatmentTransforming growth factors beta (TGF-βs) play vital roles in regulating cell growth, differentiation and inflammation....Read more
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PGD strategy in helping an obligate Hemophilia A carrier woman to have healthy children
Medical GeneticsPreimplantation genetic diagnosis (PGD) is a strategy that has been applied for high-genetic-risk couples with a known g...Read more
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SNP genotyping within INS, INSR, TCF7L2 and PPR- y genes associated with type 2 diabetes in India
Medical GeneticsA pilot population-based study was carried out to evaluate linkage between singlenucleotide polymorphisms within the kn...Read more
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Evaluating the genetic variations in functional domains coding regions of MSMB in infertile men with unexplained infertility
Medical GeneticsΒ-Microseminoprotein(MSMB) is one of the most abundant proteins in human seminal plasma. This protein binds to head and...Read more
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The effects of nano-liposomes containing curcumin on the lung cancer cell line.
Nano-Biotech MedicalLung cancer is one of the most common and malignant cancer in both sexes. The prevalence and spread of cancer in iran an...Read more
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Frequency and Pattern of Resistance of AmpC-Beta-lactamase gene in Clinical isolates of Klebsiella pneumoniae from Zahedan Educational Hospitals
Microbiology and Infectious DiseasesThe detection of CTX-M-15 genes in ESBLs produced by Klebsiella pneumoniae strains provides useful information on epidem...Read more
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Fabrication and optimization of polymeric PAA nanoparticles loaded with the natural antibacterial component, curcumin.
Nano-Biotech MedicalCurcumin is a natural polyphenol molecule derived from the Curcuma longa plant which exhibits anticancer, antioxidant, a...Read more
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Pattern of efflux pump genes in imipenem resistant Acinetobacter isolates
Microbiology and Infectious DiseasesAcinetobacter species are opportunistic pathogens and responsible for various types of nosocomial infections. They are i...Read more
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Cytotoxic activity of Berberine on the growth of breast cancer cell line (MCF-7)
Cancer; Prevention, Diagnosis and TreatmentMuch research has been conducted on the benefits of various phytochemicals in many herbs, fruits and vegetables and thei...Read more
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Reproductive Health Training Program on Students in IRAN: An Action Research Approach
Women and Reproductive HealthTransition from adolescence to adulthood is one of the important periods in the individual life. New behaviors are learn...Read more
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The effect of ziziphora extract on the expression of the Claudin_1 gene in the AGS cell line
Cancer; Prevention, Diagnosis and TreatmentClaudins are the main structural and functional proteins of tight junctions in epithelial cells. The altered expression ...Read more
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Molecular mechanism of alpha-2 adrenergic receptors in locus Coeruleus
Medical GeneticsPain is one of the most common forms of psychological stress and the most common phenomenon in medical science. Analgesi...Read more
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The Bioinformatic prediction of selected miRNAs role in regulation of cell death pathways in Parkinson’s disease
Medical GeneticsParkinson's disease (PD) is the second most common neurodegenerative disease. Due to its unknown etiology and pathology,...Read more
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In silico analysis of Siglec14 as a target for hsa-let-7e-5p
Medical GeneticsSialic acid-binding immunoglobulin-type lectins (Siglecs) are transmembrane proteins that are expressed on the cell surf...Read more
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The latest developments in pharmaceutical biotechnology
Nano-Biotech MedicalBackground and Aim: Biotechnology has produced over 200 types of drugs and new vaccines that include products for the tr...Read more
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Investigating the Verification of the Personnel Hand Hygiene Dividedly among Five Situations in Intensive Working in Namazi Hospital of Shiraz
Microbiology and Infectious DiseasesHand hygiene behavior divides into two categories: the innate hand hygiene and the selective hand hygiene. The innate ha...Read more
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The Anticancer Effect of Plant Aqueous Extracts of Aloe Vera in Gene Expression Bax and Bcl-2 on Gastric Adenocarcinoma AGS Cells
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is a major cause of cancer death. In terms of incidence is the fourth most common cancer and the second l...Read more
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Sugar-sweetened beverages increase cardiovascular risk in diabetic patients
Nutrition and HealthSugar sweetened beverages (SSBs) are any type of sugar-added drinks like soft drink, syrup, etc. SSBs consumption has in...Read more
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The Relationship between STR-PCR Chimerism Analysis and Chronic GvHD Following Hematopoietic Stem Cell Transplantation
Cancer; Prevention, Diagnosis and TreatmentGraft-versus-host disease (GvHD) is one of the serious complications of HSCT. Its prevalence has been reported as 20-50 ...Read more
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Investigating the role of Nanodrugs in the treatment of Candida and Aspergillus infectons
Microbiology and Infectious DiseasesInvasive fungal infections are a major problem for immunocompromised patients in intensive care units. Morbidity and m...Read more
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Role of Potential tumor marker in several cancer: Diagnostic and Treatment
Cancer; Prevention, Diagnosis and TreatmentTumor markers are substances produced by the tumors or by other cells of the body in response to cancer. They are produc...Read more
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Classification of Genes Related to Infectious Disease: New Hybrid Method for High Imbalanced Data Sets
Medical GeneticsGene functionality explorations has a great importance in health science research. Developing gene classifiers having ac...Read more
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Operational study of plastination as an alternate method for dissection
Nano-Biotech MedicalSince, two-thirds of the approved Zoology Laboratory syllables, defined by the Ministry of Science, Research and Technol...Read more
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Streptococcus mutans detection in Dental Plaque and saliva Samples
Microbiology and Infectious DiseasesDental caries is one of the most common prevailing disease in humans and a significant public health problem worldwide. ...Read more
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Anticonvulsant, neuroprotective and behavioral effects of magnesium sulfate on pentylenetetrazol-induced seizures in male Wistar rats
Nutrition and HealthMagnesium (Mg2+) is the second most abundant divalent and ubiquitous intracellular cation in mammalian cells and an ess...Read more
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Study of HER2 gene expression in AGS cell line after treatment of cells with Crocus sativus (Iranian Saffron) extract
Cancer; Prevention, Diagnosis and TreatmentThe study of HER-2 gene in cancers, especially gastric cancer, is of great importance. This gene, has been shown to inc...Read more
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An Evaluation of Tissue Destruction Time in Phrenic Nerve after Death and Counting the Number of Nerve Fibers in C3, C4 and C5 Branches
Cancer; Prevention, Diagnosis and Treatmentمقدمه اعصاب فرنیک چپ و راست، محرک اصلی عضلة دیافراگم میباشند( .)5ای...Read more
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Evaluation of Adenovirus in Pseudomonas aeruginosa susceptible keratitis by PCR molecular method
Microbiology and Infectious DiseasesKeratitis is inflammation of the cornea of the eye. In keratitis, microbial agents are important. In the presence of inf...Read more
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The giant lipoma pediculated in the falciform ligament: a case report
Cancer; Prevention, Diagnosis and TreatmentIntroduction: Lipoma is one of the benign and common tumors of the limbs and trunk that’s rarely occurs in the abdomin...Read more
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Effect of Crocin on mitochondrial biogenesis and Oxidative stress in the Striatum of Cholestatic rats
Medical GeneticsOxidative Stress and increment of Mitochondrial Reactive Oxygen Species (ROS) production that occurs in cholestasis whic...Read more
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Evaluation of the HLA-B46 Allelic frequency in the patients with spondyloarthritis syndrome in zanjan province
Medical GeneticsSpondyloarthritis is a group of multi-systematic disorders that has been created by spinal features, peripheral jointsan...Read more
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The role of lipids in the pathogenesis of Human T-cell leukemia virus-1 (HTLV-1) infection: a review of literature
Microbiology and Infectious DiseasesHuman T cell lymphotropic virus-1 (HTLV-1) is an oncogenic retrovirus which can cause adult T-cell leukemia lymphoma (AT...Read more
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The effects of preconditioning mesanchymal stem cells with hydrogen peroxide and serum deprivation on cell viability and apoptosis.
Stem cell and Medical ApplicationsIt is known that application of mesenchymal stem cells is an effective treatment in many diseases. Despite of cell thera...Read more
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Identifying Linking Mechanisms of Allergy and Cancer
Cancer; Prevention, Diagnosis and TreatmentAllergy and cancer are prevalent diseases and cause a lot of morbidity and mortality. In recent years, many studies have...Read more
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Modeling of cancer drugs on the route JAK-STAT in cancer stem cells
Cancer; Prevention, Diagnosis and TreatmentAbstract JAK/STAT pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for dev...Read more
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Poly(A)-tail shortening Length: an Alternative Epigenetic Mechanism for Translational Control of Oncogenes
Medical Genetics: mRNA poly(A) tails in 3'UTR is important for its stability and translation. t is observed Poly(A) tails is dynamic and...Read more
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MUC21 as a suitable candidate for immunotoxins development for targeting esophageal cancer
Cancer; Prevention, Diagnosis and TreatmentEsophageal cancer is the world's eighth most common cancer and the sixth most common cause of cancer death in the world....Read more