• Time and Surgery Duration Effects on Renal Function Tests in Patients with Laparoscopic Cholecystectomy
  • Ahmad Reza Shahraki,1,* Elahe Shahraki,2 Elham Shahraki,3
    1. General Surgeon ,Assistant professor, Department of General Surgery ,Zahedan Medical Faculty , Zahedan University of Medical Sciences and Health Services, Zahedan, Iran.
    2. Dentist, Periodontology resident, Dental Faculty, Tehran University of medical Sciences, Tehran, I.R. Iran.
    3. Associated professor of Nephrology, Department of Internal medicine, Nephrologist, Ali Ibne Abitaleb Hospital, Zahedan University of medical Sciences, Zahedan, I.R. Iran


  • Introduction: Background: Laparoscopic Cholecystectomy is one of the most common elective surgical procedures and is a minimally invasive surgical Procedure for patients with gallbladder diseases. Objectives: This study aimed to evaluate the effect of laparoscopic cholecystectomy time and duration of surgery on Renal function Tests among patients undergoing the surgery in Ali Ibn Abi Taleb Hospital in Zahedan (South east of Iran).
  • Methods: Following a quasi-experimental design, 21 cases scheduled for laparoscopic cholecystectomy for whatever reasons at Ali Ibn Abi Taleb Hospital in Zahedan (Iran) selected. To study the serum levels of Renal function Tests, blood samples were collected in third stages, i.e., before the surgery (time point 1), 30 minutes after pumping the carbon dioxide gas into the abdomen (time point 2), and 30 minutes after removing the last port from the abdomen (time point 3). Data were analyzed using repeated measures. Time of surgery measured from starting induction of anesthesia for first step and second step from pumping the carbon dioxide gas into the abdomen. Finishing time is third step and gas exit from abdomen and forth step is extubation of patient.
  • Results: Results: According to the findings, laparoscopic cholecystectomy surgery only had a significant effect on the BUN at the 99% confidence level. Also, BUN was increased and significantly differed at time points 2 (30 minutes after pumping) and 3 (30 minutes after removing the port) compared to time point 1 (30 minutes before the surgery).
  • Conclusion: Conclusions: Generally, it can be argued that despite observing some variations in the BUN test during the laparoscopic surgery, the Cr level did not change. Hence, it can be considered as a safe surgical intervention for renal functions. Time and duration of surgery cannot effect on renal function tests.
  • Keywords: laparoscopic cholecystectomy; renal function tests; laparoscopy; time