مقالات پذیرفته شده در نهمین کنگره بین المللی زیست پزشکی
Comparison of the effects of eight weeks of aerobic and polarized training on pulmonary function, inflammatory markers, and vascular endothelial growth factor in active young girls
Comparison of the effects of eight weeks of aerobic and polarized training on pulmonary function, inflammatory markers, and vascular endothelial growth factor in active young girls
Bahar Saljoughi Beranji,1Fatemeh Mirershadi,2Hooman Ravaei,3Marefat Siahkouhian,4,*
1. M.Sc. Student in Exercise Physiology, Department of Exercise Physiology, Faculty of Education and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran 2. Department of Physiology, Faculty of Medicine, Ardabil Branch, Islamic Azad University, Ardabil, Iran 3. Young Researchers and Elite Club, Ardabil Branch, Islamic Azad University, Ardabil, Iran. 4. Department of Exercise Physiology, Faculty of Education and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran
Introduction: Regular physical activity is recognized as a non-pharmacological intervention that enhances respiratory efficiency, regulates inflammatory processes, and promotes vascular health. Recent evidence highlights the role of aerobic and polarized training in modulating pulmonary function, systemic inflammation, and angiogenic factors such as vascular endothelial growth factor (VEGF). This study aimed to compare the effects of eight weeks of aerobic versus polarized training on pulmonary function, inflammatory biomarkers, and VEGF levels in physically active young women.
Methods: In this quasi-experimental pre–post design, thirty active female participants were randomly allocated to aerobic training, polarized training, or control groups. Interventions consisted of three sessions per week for eight weeks. Pulmonary function—Forced Vital Capacity (FVC) and Forced Expiratory Volume in one second (FEV₁)—was measured using spirometry. Serum levels of C-reactive protein (CRP), creatine phosphokinase (CPK), and VEGF were quantified using standardized ELISA protocols. Data analyses included one-way ANOVA for baseline homogeneity, paired t-tests for within-group changes, and ANCOVA for between-group comparisons, with Bonferroni post-hoc testing where applicable (p < 0.05).
Results: Both aerobic and polarized training significantly improved FEV₁ and FVC compared with control (p < 0.05). CRP levels decreased markedly in both intervention groups, indicating strong anti-inflammatory effects, while CPK changes were not statistically significant. VEGF concentrations rose significantly in the training groups relative to control (p < 0.05). Effect size analysis revealed that polarized training induced the largest improvement in FVC (1.31), whereas aerobic training elicited the strongest gains in FEV₁ (1.06). Reductions in CRP (–1.32 and –1.09 for aerobic and polarized groups, respectively) underscored clinically meaningful anti-inflammatory adaptations.
Conclusion: Eight weeks of aerobic and polarized training effectively enhance pulmonary function, attenuate systemic inflammation, and stimulate VEGF-mediated vascular responses in active young women. These findings underscore the potential of structured exercise programs as non-pharmacological strategies for improving respiratory and vascular health, supporting recent biomedical research linking exercise intensity distribution with cardiopulmonary resilience and angiogenic regulation.