• Anti-aging natural supplements: the main players in promoting healthy lifespan
  • Mehran Izadi,1 Nariman Sadri,2 Amirhossein Abdi,3 Mohammad Mahdi Raeis Zadeh,4 Dorsa Jalaei,5 Safa Tahmasebi,6,*
    1. Department of Research & Technology, Zeenome Longevity Research Institute, Tehran, Iran
    2. Department of Research & Technology, Zeenome Longevity Research Institute, Tehran, Iran
    3. Department of Research & Technology, Zeenome Longevity Research Institute, Tehran, Iran
    4. Department of Research & Technology, Zeenome Longevity Research Institute, Tehran, Iran
    5. Department of Research & Technology, Zeenome Longevity Research Institute, Tehran, Iran
    6. Department of Research & Technology, Zeenome Longevity Research Institute, Tehran, Iran


  • Introduction: Aging is an inevitable process marked by physiological decline and increased risk of disease. Natural compounds with anti-aging potential have gained attention for promoting healthy lifespan. Among these, Omega-3 fatty acids, Coenzyme Q10, Gingerol, and Curcumin are of special interest due to their diverse biological activities that may support longevity and improve quality of life.
  • Methods: This review examines recent scientific studies on four natural compounds—Omega-3, Coenzyme Q10, Gingerol, and Curcumin. Evidence on their mechanisms, including anti-inflammatory, antioxidant, mitochondrial, and anti-aging effects, is synthesized to assess their role in mitigating age-related conditions.
  • Results: The findings suggest that Omega-3 reduces inflammation, Coenzyme Q10 enhances mitochondrial energy, Gingerol provides strong antioxidant defense, and Curcumin exhibits broad anti-aging properties. Together, these compounds show promise in slowing age-related decline and promoting healthier aging.
  • Conclusion: Natural supplements such as Omega-3, Coenzyme Q10, Gingerol, and Curcumin play important roles in supporting health during aging. Their combined effects may enhance lifespan and quality of life, although further clinical studies are needed to confirm their long-term efficacy and safety.
  • Keywords: Aging Omega-3 Coenzyme Q10 Gingerol Curcumin