مقالات پذیرفته شده در نهمین کنگره بین المللی زیست پزشکی
Prevalence of bacterial vaginosis in women with infertility problems among patients referred to medical centers in Shiraz.
Prevalence of bacterial vaginosis in women with infertility problems among patients referred to medical centers in Shiraz.
Fatemeh Bahrami Chegeni,1,*
1. PhD student in Microbiology, Islamic Azad University, Kazerun Branch, Kazerun, Iran
Introduction: Bacterial vaginosis (BV) is a polymicrobial syndrome described by vaginal itching, vaginal discharge, odorous, and/or burning. BV can occur when vaginal lactobacilli are replaced by different anaerobic bacteria. Bacterial vaginosis is one of the most common infections in women. Various antibiotics have been used to treat these infections.
This study was aimed to determine the prevalence of bacterial vaginosis among women with unexplained infertility problems
Methods: A total of 65 infertile women, who referred to obstetrics and gynecology clinics in Shiraz City for suspected vaginal infections, were tested for possible BV. Interviews were performed to collect data on socio-demographic characteristics, history and characteristics of vaginal discharge. BV was diagnosed by laboratory methods according to the Amsel criteria. The presence of Gardnerella vaginalis, Atopobium vaginae, was verified by polymerase chain reaction (PCR) using specific primers on the DNA extracted from the vaginal specimens.
Results: Among women tested for suspected vaginal infections, 28 cases of BV (19 symptomatic and 9 Asymptomatic) were confirmed using defined criteria. In 65% and 35% of these BV cases, the presence of G. vaginalis and A. vaginae was confirmed by PCR, respectively.
Conclusion: The prevalence of BV was high among patients with unexplained infertility. The cultural and socio-economic factors contribute to the risk of the condition.