Introduction: The body reacts to many types of injury by causing inflammation, and inflammation is thought to be part of the immune system, but it can also cause your body to behave badly. Ulcerative colitis is an inflammatory disease that affects many people around the world. Ulcerative colitis has no cure. Ulcerative colitis affects the digestive tract and causes ulcers and swelling of the mucosa from rectal till the end of the colon. Signs include diarrhoea, bloody faeces, abdominal pain, etc. It is an intestinal disorder caused by environmental factors such as lifestyle, smoking, dietary habits, etc. This disease can affect people of all ages, although it is important to note that it is less severe in people over 60 years of age than in younger people. Although a cure for this disease has not been found, current science can prevent its progression and reduce its symptoms to some extent. This ailment is recovered by seafood, immunosuppressants, aminosalicylic acid, corticosteroids, and medicines such as mesalazine.
Methods: Clinical information was obtained from blood tests, stool samples and a review of a colonoscopy, as well as from consultation with the individual physician of the patient.
Results: A review of clinical records and tests performed on the subject revealed high calprotectin and elevated eosinophils, indicating inflammation in the body and possible parasite involvement in this inflammation. Further investigation of the tests carried out revealed that the parasite, which is known as Entamoeba histolytica, causes inflammation and haemorrhage.
Conclusion: Entamoeba histolytica is a parasite that causes intestinal inflammation and ulcerative colitis. Mesalazine, given in the form of tablets, suppositories and enemas in different doses, controlled the disease and reduced its severity in this patient. Research in these diseases shows that cell gene expression profiling by microarrays on inflammatory tissue biopsies helps to assess the disease more accurately and to make better decisions about how to treat it; molecular and cellular changes are more closely related to disease activity than in clinical examination and can be used to predict disease progression. Recent advances in medical science have raised the prospect of a complete cure for the disorder.