• Investigation of the antimicrobial effects of probiotic lactobacilli isolated from whey on on rectovaginal streptococcus agalactiae isolates isolated from pregnant women
  • Seyed mohammad mahyar Yasini,1 Nariman Jafari,2 Yasna Azizpour,3,*
    1. Department of Biology, SR.C., Islamic Azad University, Tehran, Iran.
    2. Department of Biology, SR.C., Islamic Azad University, Tehran, Iran.
    3. Correspondence should be addressed to Yasna Azizpour, Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.


  • Introduction: Congenital infections are a significant concern in fetal health. This article discusses Group B Streptococcus (GBS) infections among pregnant women. This bacterium can evade the immune system in multiple ways, disrupting the balance of genital microflora, which is vital for protecting women against bacterial infections in the reproductive tract. When beneficial microflora such as lactobacilli are deficient, this balance is disturbed, increasing the risk for both the mother and the fetus during pregnancy. In this research, in addition to analyzing these bacteria, various therapeutic agents and methods are also investigated, which are referred to as biotics and probiotics, respectively. Since antibiotic resistance is increasing, we aim to find a solution that not only treats the disease but also mitigates the rise of antibiotic resistance.
  • Methods: To achieve the objectives of this study, databases such as Google Scholar and PubMed were searched using terms related to Streptococcus agalactiae, probiotics and pregnant women, to find articles relevant to the research topic.
  • Results: The results and statistics show that the studied antibiotics, such as tetracycline, may contribute to bacterial resistance. For this reason, it is suggested that probiotics be used to replace antibiotics because they reduce the persistence of GBS.
  • Conclusion: Findings suggest that both probiotics and antibiotics are essential for preventing infections in pregnant women; however, probiotics are considered more effective. Additionally, the study proposes that future research should prioritize investigations into probiotics and their biological significance in clinical contexts.
  • Keywords: Streptococcus agalactiae, microflora, pregnancy, antibiotic, probiotic