مقالات پذیرفته شده در نهمین کنگره بین المللی زیست پزشکی
Shingle vaccination and treatment review article
Shingle vaccination and treatment review article
Kimia Parsi,1,*Saman Hakimian,2
1. Ms.c Microbial Biotecnology Tehran Islamic Azad University of Medical Sciences. Genetics Bachelor . 2. M.sc studet of pathogenic Microbes Islamic University Centeral Branch
Introduction: Shingles is a viral disease characterized by a painful rash on two side of the body. The skin lesions are usually localized to the left and right side of the body or on the face. Two to four days before the rash appears, there may be tingling, itching, or localized pain in the area. Other common symptoms include fever, headache, and fatigue. The skin lesions caused by shingles usually resolve within two to four weeks, but some people develop persistent nerve pain that can last for months or even years, a condition called postherpetic neuralgia.
Methods: Varicella-zoster virus is a DNA virus and one of nine known herpesviruses that can infect vertebrates. It is the causative agent of two well-known diseases, chickenpox and shingles, which are commonly seen in children and adults, respectively. VZV is structurally very similar to herpes simplex virus. The glycoproteins that make up the VZV envelope have a remarkable similarity to the HSV envelope.
Varicella-zoster virus is known by a variety of names. These include: chickenpox virus, varicella virus, zoster virus, and human herpesvirus type 3.
Results: Antiviral medications such as acyclovir and herbal antiviral ointments such as Mirtoplex, Aftoplex and Melissane may be more effective if started after the appearance of skin lesions and may reduce the severity and duration of the illness. Paracetamol, NSAIDs or opioids may be used to help with acute pain.
Shingles vaccines reduce the risk of shingles by 50 to 90%, depending on the type of vaccine use. Vaccination also reduces the amount of nerve pain after infection and, if shingles does occur, reduces its severity.
Common symptoms include headache, mild fever and chills, malaise, red blisters, pain, feeling tired, and nausea.
Shingles is caused by the reactivation and replication of dormant viruses in spinal cord cells.
Conclusion: In people with weakened immune systems(such as people with cancer, HIV, organ transplant recipients, or those undergoing chemotherapy,Have been ill,Have experienced trauma ,Are under stress.). the skin lesions may be widespread. If the rash involves the eyes, vision loss is possible.