مقالات پذیرفته شده در نهمین کنگره بین المللی زیست پزشکی
Study of the antibiotic resistance pattern in Staphylococcus aureus bacteria isolated from urinary tract infections in women referred to Fajr Clinical Laboratory in Oshnavieh County during the years 2021-2024
Study of the antibiotic resistance pattern in Staphylococcus aureus bacteria isolated from urinary tract infections in women referred to Fajr Clinical Laboratory in Oshnavieh County during the years 2021-2024
Introduction: Urinary tract infections are the most common bacterial infection in women. They usually occur between the ages of 16 and 35, with 10% of women having an infection each year and 60% having an infection at some point in their lives. They can also occur in childhood.
Although Staphylococcus aureus is a relatively uncommon cause of urinary tract infections, accounting for 0.5 to 6% of urinary tract infections, untreated urinary tract infections caused by this microorganism can lead to serious complications such as sepsis.
Given the increasing antibiotic resistance and the problems that this resistance has created in the treatment system, this study investigated the antibiotic resistance pattern in Staphylococcus aureus bacteria isolated from urinary tract infections of women referred to the Fajr Clinical Laboratory in Oshnavieh County during the years 2021-2024.
Methods: In this cross-sectional-descriptive study, 50 isolates of Staphylococcus aureus were isolated from women referred to the Fajr Clinical Laboratory in Oshnavieh County during the years 2021-2024 and were examined. Staphylococcus aureus isolates were identified using biochemical methods. Polymerase chain reaction (PCR) was also used to confirm the identification of the S. aureus species using primers specific for the nuc gene (encoding a heat-resistant nuclease).
The disk diffusion method was used to determine the antibiotic resistance pattern of S. aureus isolates.
Results: The highest resistance of the tested S. aureus isolates was observed to methicillin (86.6%), penicillin (86.6%), and cefixime (82.3%), respectively. The highest sensitivity of the tested S. aureus isolates was observed to trimethoprim-sulfamethoxazole (88.1%).
Conclusion: The present study demonstrates the high resistance of S. aureus isolates isolated from female urinary tract infections. Therefore, in order to prevent the increase in resistance to common antibiotics, over-the-counter and indiscriminate use of antibiotics should be avoided.