Introduction: Nowadays, antibiotic resistance is increasing due to overuse, and this issue has caused concern all over the world. Ciprofloxacin is a broad-spectrum antibiotic that is used in the treatment of many infections, including urinary tract infections. Knowing the status of strains causing urinary tract infections against common antibiotics, including ciprofloxacin, is of particular importance in the treatment process. In the present study, the sensitivity of bacteria isolated from urinary tract infections to ciprofloxacin was investigated.
Methods: In this study, which was conducted over a period of one year in 1402, out of 820 urine culture samples referred to the laboratory, 135 samples were positive and were isolated and identified by biochemical methods. The sensitivity of bacteria to ciprofloxacin was investigated by the disk diffusion method and also by determining the minimum inhibitory concentration (MIC).
Results: The isolated strains included 8 strains, the most common of which were Escherichia coli (65.9%) and Staphylococcus aureus (19.2%). Among them, 17 strains (19.1%) of Escherichia coli and 6 strains (23%) of Staphylococcus aureus were resistant to ciprofloxacin.
Conclusion: The results of this study show that resistance to ciprofloxacin is relatively high among bacteria causing urinary tract infections and this increasing antibiotic resistance can cause treatment problems. Therefore, tracking resistance in different regions and knowing the level of resistance, especially the MIC of resistant strains, can be a way to appropriately use this valuable antibiotic.