• Manifestations of elements and minerals deficiency in the oral cavity
  • Hamideh Kadeh,1 Shirin Saravani,2,*
    1. Oral & Dental Disease Research Center, Department of Oral & Maxillofacial Pathology, School of Dentistry, Zahedan University of Medical Science, Zahedan, Iran
    2. Oral & Dental Disease Research Center, Department of Oral & Maxillofacial Pathology, School of Dentistry, Zahedan University of Medical Science, Zahedan, Iran


  • Introduction: Nutritional deficiencies can affect all or part of the oral tissues such as teeth, periodontal tissues, salivary glands, mucous membranes and perioral skin. Elements and minerals play an important role in the balance of the body's normal metabolism, often in the form of cofactors.
  • Methods: An electronic search was conducted in Medline and Scopus limited to English language publications using key words Malnutrition, Minerals, Mouth, Oral pathology.
  • Results: Elements such as magnesium, calcium, and phosphorus in the diet are the main structural compounds in teeth. Also, calcium, zinc and iron are the most important elements with oral manifestations when deficient. Calcium deficiency is associated with an increased risk of periodontal disease and tooth loss. Fluoride in fluoridated water sources and toothpaste is associated with reduced tooth decay and enamel health. Iron deficiency is one of the most common diagnoses in the adult population, and the oral manifestations of iron deficiency are similar to those of B12 and folate deficiency, in which glossitis is a common finding. Recurrent aphthous stomatitis, as well as angular stomatitis and paleness of the oral mucosa due to anemia can also be other symptoms. Peripheral dermatitis in zinc deficiency thins the upper lip and takes on the appearance of a horseshoe shaped. Other symptoms of zinc deficiency may include flattened filiform papillae, impaired wound healing and xerostomia.
  • Conclusion: According to the Oral cavity may manifest early signs of nutritional deficiency, in this study, we discuss about oral manifestations due to deficiency of elements and minerals.
  • Keywords: Malnutrition, Minerals, Mouth, Oral pathology