• The effects of prebiotics on the proliferation and survival of probiotic bacteria and its effect on strengthening the immune system to fight the corona virus disease.
  • Afagh shams,1 Shakila shams,2,*
    1. Eighth grade student, hazrat Zeinab talents high school.
    2. Seventh grade student, hazrat Zeinab talents high school.


  • Introduction: Since the outbreak of Covid 19 disease, humans have been looking for ways to prevent it. Strengthening the immune system is one of the main ways to prevent pandemic diseases such as Covid 19. Recently, the use of probiotics to improve digestion and immunity has been considered in the dairy industry. The aim of this study was to investigate the effects of prebiotic fructooligosaccharide prebiotic on the growth and persistency of the probiotic bacterium "Bifidobacterium" and to investigate the different properties of the resulted synbiotic yogurt.
  • Methods: This study was conducted in the year 1399. In evaluating the effects of prebiotics, dilution of probiotics and prebiotic bacteria containing yogurts was performed with using Ringer's solution. To cultivate, birch agar medium containing mupirocin was used. Growth curve and retention curve as well as sense evaluating were recorded in the presence of different concentrations of prebiotics.
  • Results: The results showed that the growth of probiotic bacteria in the presence of prebiotics increased 10 times. At the standard level of probiotic bacteria in yogurt (1,000,000 colonies /ml ), probiotics yogurt had a shelf life of 10 days,but Sinbiotic yogurt retains its beneficial effects for 15 days.
  • Conclusion: According to the findings of this study, the prebiotic "fructooligosaccharide" has some direct effects on increasing the growth and persistence of the probiotic bacterium "Bifidobacterium" in yogurt. As the results, it has significant effects on strengthening the immune system, in order to fight against Covid 19 disease. Synbiotic yogurt is recommended for daily consumption.
  • Keywords: Probiotics yogurt, Peribiotics, Synbiotics yogurt,Bifidobacterium bacteria, Fructooligosaccharide.