• Does the HPV vaccine have side effects or other cons? A systematic overview
  • Somayeh Nikkhah,1,*


  • Introduction: The human papillomavirus (HPV) affects nearly 80 millionTrusted Source people in the United States. Some of its types can cause medical concerns, from genital warts to cervical cancer.The HPV vaccine is a safe and effective vaccine that can protect children and adults from HPV-related diseases. In this study, we investigated the possible side effects of the HPV vaccine.
  • Methods: In this systematic review was performed using the key words HPV vaccine AND side effects in Scopus, PubMed, ScienceDirect, Google Scholar, Iranmedex databases, Until March 2020, and finally 18 articles were examined in this regard.
  • Results: The HPV vaccine protects against some types of HPV-related cancers and and genital warts. HPV vaccination demonstrated that the vaccine is as safe as any other vaccination. Most people receive the HPV vaccine without having any serious side effects. Mild to moderate side effects occur more often but are still uncommon. Mild to moderate side effects can include: pain or swelling at the injection site, slight fever, headache, fatigue, muscle pain, joint pain, fainting, nausea vomiting, pain in the abdomen, diarrhea. The vaccines don’t prevent all HPV related cancers, only some. Therefore, it’s vital that women still get a routine Pap test to check for any signs of cervical cancer. The vaccines don’t protect against other sexually transmitted infections (STIs) or treat existing HPV-related illnesses or infections. It is necessary need to use condoms or other barrier methods during sex to help prevent contracting or transmitting STIs. The HPV vaccine does not affect fertility and may improve fertility in some women who’ve been exposed to STIs.
  • Conclusion: The studies support that people who receive this vaccine are not at a higher risk of any negative events.
  • Keywords: HPV Vaccine- Side Effects – Protection