Introduction: We remember that Amniocentesis is the most common method used to diagnose aneuploidy and other genetic abnormalities in the fetus. The amniocentesis needle should be avoided when entering the placenta when possible. The aim of this study was to investigate the association between amniocentesis complications and needle passage through the placenta.
Methods: This study was a cohort study on 700 pregnant women who were candidates for amniocentesis referred to Perinatology Clinic of 19 Mayis Research Hospital in Samsun, Turkey from 2017 to 2019. In these subjects, a special needle and ultrasound guidance were inserted into the pregnancy sac and approximately 20 cc of amniotic fluid was drawn. Needle passage or non-passage of the recorded placenta and complications during pregnancy such as miscarriage, spotting, preterm labor, and rupture of the sac were evaluated and compared in each group.
Data analysis was done in SPSS applying
Kolmogorov-Smirnov test, t-test, and Chi-square. The relative risk (RR) was also calculated.
Results: The mean age of participants was 30.2 years old (19-44 years of age). Spotting after
amniocentesis was recorded in 1.4% nontransplacental amniocentesis and in 6.1% of transplacental
amniocentesis (RR; 6.85, p=0.03). There was no significant relationship between needle passage through
the placenta and other complications such as abortion, amnionitis, preterm labor, and amniotic fluid
leakage following amniocentesis (p=0.08).
Conclusion: Current findings showed that transplacental amniocentesis increases the probability
of spotting following amniocentesis.