مقالات پذیرفته شده در سومین کنگره بین المللی زیست پزشکی
Nanotechnology and Cancer
Nanotechnology and Cancer
Razieh Fazel ,1Sara Askari,2,*omid backraiy,3Sara Shojaei,4Somaye Portalebi,5
1. MSc student Parasitology Research Committee, Jahrom University of Medical Science, Jahrom, Iran 2. Bachelor student Laboratory Science, Tabriz University of Medical Science, Tabriz, Iran 3. MSc student Parasitology Research, Shahid Chamran University of Medical Science, Ahvaz, Iran 4. Bachelor student Laboratory Science, Shiraz University of Medical Science, Shiraz, Iran 5. MSc student mycology ,Rafsanjan University of Medical Science, Rafsanjan, Iran
Introduction: The application of nanotechnology in medicine relation to identification and root cancers focus of researches in worldwide. Nanotechnology can help bring about radical changes in the ways of cancer treated and its caregiving practices. Currently, cancer diagnosis and diagnosis is usually based on changes in cells and tissues, which can be done by clinical trials or conventional imaging modalities. Nanoparticles play a vital role in transforming knowledge into useful clinical advances in the diagnosis and treatment of cancer cells.
Methods: In this systematic review, after reviewing the Sid information source and the google scholar search engine, and using library searches, the Nanoparticles and Cancer keywords were achieved. The criteria for entry of articles include from 2011 to 2019, the full text of articles was accessible.
Results: The use of nanoparticles as a drug and for the treatment of malignant cancer cells have no adverse effect on healthy cells and tissues of the body. Once these nanoparticles reach the tumors, the drugs inside them are activated by narrow bands of laser light. These nanoparticles are also able to determine the effect of treatment on malignant cells. One of the most promising applications of the nanoparticles can be their application to perform both tumor detection and drug delivery simultaneously. The nanoparticles used to treat cancer include:
Nanoparticles involved in the treatment of cancer include, Nanocavities allow the passage of only one single strand of DNA, nanocrystals have a central core structure with a thin membrane of gold-like metal lined with an outer laser and energy transfer to the nanocrystals in a tumor that can be thermally destroyed or imaged or repaired. The wound is used for magnetic nanoparticles, which iron oxide is one of the main components. The most important advantage of using these particles is smaller than 100 nm. Its use for transferring DNA into cells is the treatment of cancerous masses with heat treatment, MRI imaging and hyper thermia, magnetic separation of materials, and use in tissue engineering.Also
the new PCS system also retains the ability to target the compound by blocking the absorption of blood protein, preventing them from being unintentionally cleared by the monolayer phagocyte. Silicon nanoparticles are also used. The development of exosome-coated, nanosized porous nanoparticles that are also biocompatible for targeted cancer chemotherapy has led to increased enrichment of anticancer drugs in tumor cells.
Conclusion: Although there are still challenges invitro and limitations to use of nanoparticles in medicine, it is hoped that in the near future, nanoparticles will create not only oncology but also revolutionary medicine.