مقالات پذیرفته شده در سومین کنگره بین المللی زیست پزشکی
Evaluation of prevalence of common bacteria in urinary tract infection and their antibiotic resistance pattern in children under two years old hospitalized in Sabalan Ardabil Hospital in the first trimester of year 1398
Evaluation of prevalence of common bacteria in urinary tract infection and their antibiotic resistance pattern in children under two years old hospitalized in Sabalan Ardabil Hospital in the first trimester of year 1398
Shadi Mohajer Momtaz,1Mohammad Hasan Astan,2,*Morsal Hatami,3
1. M. A., Department of Microbiology , Ardabil Branch, Islamic Azad University, Ardabil, Iran 2. M. A., Young Researchers and Elite Club, Ardabil Branch, Islamic Azad University, Ardabil, Iran 3. M. S., Expert on infection control, Sabalan Hospital, Ardabil, Iran
Introduction: One of the most common human infections is urinary tract infection. Bacterial factors, especially Escherichia coli, are among the most plenitude microorganisms. Antibiotics are used to treat this infection, which are ineffective in most cases due to antibiotic resistance. The goal of this study is to determine the pattern of the urinary tract infection producing microorganisms and the antibiotic resistance of these microorganisms.
Methods: In this descriptive -periodical study, from January 1 to March 28, 422 samples were referred to the lab , which aged least 3 days and maxed out to a maximum of one and a half years. 120 samples were positive. Samples were cultured in Blood agar, EMB, Macconkey agar and samples more than or equal to 105 considered as positive. To determine bacterial existing, biochemical tests, such as Gram stain and TSI, were used. for sensitivity test, 30 antibiotics were used under disk-diffusion (Kirby-Bauer) condition on a Muller Hinton Agar culture environment, and the diameter of the growth hole was determined based on NCCLS and data was processed in SPSS software.
Results: From 120 specimens, 65 samples are for males and 55 for females. The most pathogenic bacterium was Escherichia coli, which include 24 specimens. Staphylococcus aureus includes 17 specimens and Klebsiella with 15 samples are in the next ranking. Antibiotics such as nitrofurantoin and Cotrimoxazole with 26 times and Gentamicin with 22 times usage were antibiotics with the most consumption for sensitivity test .On the other hand, Cotrimoxazole with 39 times and ampicillin with 32 times and Gentamicin with 29 times showed the highest resistance.
Conclusion: Further studies are needed to develop an antibiotic resistance pattern in each province, and efforts are needed to replace new therapies and raise public awareness for the proper use of drugs.