• A Review of Medicinal Herbs Capable of Preventing Blood Coagulation and Platelet Aggregation
  • MOHAMMAD YAZDI,1,* Hossein Eliasy ,2
    1. Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran
    2. Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran


  • Introduction: Blood coagulation is a process carried out to prevent blood loss when a person is wounded. The blood coagulates in the wound place and creates a barrier which prevents bleeding. The blood coagulation process is one of the most important and vital physiological processes in the human body which is affected by many factors. Many congenital and acquired defects in each of these factors can affect the coagulation process and cause many problems for humans.
  • Methods: So far, many medicinal plants have been discovered that have various properties on the human coagulation system. Since ancient times, some plants have been used, even topically, to stop the bleeding of the wound. Furthermore, other herbs which are still in use and often have dramatic effects, are used either orally to strengthen the body's coagulation system or as a source of vitamin K. Besides, some herbs are used by people who have high blood concentration level for the purpose of the dilution of their blood and prevention of diseases and problems. These plants are Erigeron Canadensis, Urtica dioica, Angelica genuflexa, Paeonia lactiflora, Paeonia suffruticosa, Rheum undulatum, Ferula communis, Cinnamomum cassia, Glycyrrhiza glabra, Allium sativum L., Acacia nilotica L., Angelica pubescens Maxim, Artemisia capillaris Thunb., Cinchona officinalis L., Ginkgo biloba L., Ginkgo biloba L., Camellia sinensis, Artemisia herba, Melilotus officinalis, Bauhinia forticata L., and Eleutherococcus senticosus.. Plants with anti-platelet aggregation effect: Urtica dioica. Angelica genuflexa. Artemisia capillaris Thunb. Cinchona officinalis L.. Ginkgo biloba L.. Camellia sinensis Plants with Anti-Blood Coagulation Effect : Ferula communis. Glycyrrhiza glabra. Artemisia herba. Melilotus officinalis. Bauhinia forticata L. Plants with Anti-Blood Coagulation Effect and anti-platelet aggregation effect: Erigeron canadensis . Paeonia lactiflora and Paeonia suffruticosa. Rheum undulatum, Cinnamomum cassia. Allium sativum L. Acacia nilotica L. Angelica pubescens Maxim. Eleutherococcus senticosus…
  • Results: Among the most important properties of medicinal plants is the lack of or low level of side effects and drug interactions. Anti-Coagulant Properties of the Surveyed Medicinal Plants: Twenty medicinal plants were found to have effective active ingredients for inhibiting platelet aggregation and blood coagulation
  • Conclusion: One of the major goals of this study was to create a scientific and appropriate literature review of effective medicinal herbs with anticoagulation effects. In this study, 20 medicinal herbs were selected and examined. One of the conclusions that can be drawn from this study is that many of the plants with anti-coagulant activity belong to the Fabaceae family. ..Finally, this study indicated that there are many medicinal herbs that have different effective substances to prevent blood coagulation by various mechanisms. These plants can be considered as highly significant and efficient resources for producing valuable drugs against diseases that are caused by blood coagulation. Some of these plants naturally grow in nature and the rest are easily nurtured. Hence, medicinal herbs can be converted into drugs which, despite having complex and valuable materials, have a very low production cost and other benefits including low side effects
  • Keywords: Medicinal plants, coagulation, coagulation factors