مقالات پذیرفته شده در سومین کنگره بین المللی زیست پزشکی
Treatment of periodontal soft tissue with cell therapy
Treatment of periodontal soft tissue with cell therapy
amirali-babavali,1,*
1. Biomedical engineering, Energy institute of higher education, Saveh, Iran.
Introduction: Gum disease is one of the most commonly diagnosed diseases in the world. If the disease is not treated, it can have irreparable consequences. Currently, a new method has been found that can solve the problem. In a new study, scientists discovered a combination of biological and mechanical techniques to repair and regenerate bone and gingival tissues. One of the symptoms of gum disease is bleeding and gum color changes. The inflamed gums become red and bleed with the slightest irritation. The dentist should be sure of the health of the teeth and gums, with regular visits every three months to the dentist. With the accumulation of pathogenic microorganisms on the teeth due to inadequate health, deeper tissues are involved and periodontal fibers are degraded, gingival adhesion to the teeth will be reduced and the periodontal envelope will be formed. When bone inflammation occurs, bone resorption is irreversible and its treatment requires the use of specialized therapies.
Methods: In the context of this overview, 14 articles were used between the years 2017 through the 2019 using the keywords of PubMed, Google scholar search engines.
Results: For decades researchers have sought ways to repair the damage which occurs during periodontitis. This has included the use of a range of surgical procedures, the use of a variety of grafting materials and growth factors, and the use of barrier membranes. To date periodontal regeneration is considered to be biologically possible but clinically unpredictable. Recently, reports have begun to emerge demonstrating that populations of adult stem cells reside in the periodontal ligament of humans and other animals. This opens the way for new cell‐based therapies for periodontal regeneration.
Conclusion: Regeneration of tissues destroyed by periodontitis has long been an altruistic goal of periodontal therapy. Periodontal regeneration requires consideration of many features that parallel periodontal development, including the appropriate progenitor cells, signaling molecules and matrix scaffold in an orderly temporal and spatial sequence.