• Nano Biosensors
  • mohadeseh ghorbani,1 Fearzane Jabari,2,*
    1. Biomedical engineering, Maziar University, Royan, Mazandaran, Iran.
    2. PHD condidate of Biomedical Engineering (Biomaterial) , Materials and Energy Research Center (MERC) , Alborz , Iran


  • Introduction: Over the past years, many devices have been found for timely diagnosis of diseases.The newest and most efficient device for detecting pathogens are biosensors. New technologies that can be used to improve biosensor performance are nanotechnology. The use of nanoparticles as biomarkers in the semiconductor quantum dot technique is one of the most interesting aspects in detecting pathogens.Nanosensors are also used to find biomarker molecules for disease assessment.The Nano Biosensortechnology represents a combination of biochemistry, molecular biology, chemistry, physics, electronics, and computers. Nano Biosensorsare a powerful tool for identifying biological molecules; today they are used in various sciences such as medicine, chemical industry, food industry, environmental monitoring, pharmaceutical and healthcare products, and so on. This research was conducted with the aim of examining Nano Biosensorsin the biological sciences.
  • Methods: In the context of this overview, 15 articles were used between the years 2010 through the end of 2019 using the keywords of PubMed, google scholar search engines
  • Results: Nano Biosensors are analytical tools that can detect combinations and react with them by using the intelligence of biological materials, and thus produce a chemical, optical or electrical message. The basis of the work of a biosensor is the conversion of a biological reaction to a message. Nano Biosensors are made up of three parts: (1) bioreceptor or bioassay, (2) converters, and (3) detectors. The presence of completely dedicated bioreceptors is the reason for the unique features of the Nano Biosensors. In fact, the basis for the identification and measurement of compounds in these systems is the specific analysis of the analyte being measured to the sensor by bioreceptors. Bioreceptorsused in biosensors are: 1. Enzyme 2. Antibody 3. Cellular receptors 4. DNA or RNA Nucleic acid 5. Microorganism or complete cell 6. Tissue 7. Synthetic receptors. The importance of these components IS their highly specialized performance compared to special analyte that prevents interference with intrusive materials, which causes the inefficiency of many measurement methods to be ineffective. The biologic component may catalyze the reaction of the substrate or selectively connect to the superstructure.
  • Conclusion: Nano Biosensors are one of the most recent developments in biotechnology, which seems to have been the subject of extensive research in recent years. These developments have been accompanied by an increase in the need for measuring instruments that can continuously review biological processes. Nano Biosensors can be a very good alternative to traditional methods of diagnosing biological agents and one of the most promising solutions to the problems of the simplicity, fastness, repeatability and low cost of multi-agent detectors for biological agents. Therefore, Nano Biosensors can be very helpful in identifying biological agents and resolve the challenges posed by the detection of biological agents to a large extent.
  • Keywords: Key words: bio sensors, detector, analytes