• review article: A novel method for cancer treatment
  • Mahdis, Ameri,1 Farzane, Jabari,2,*
    1. Biomedical engineering, Maziar University, Royan, Mazandaran, Iran
    2. PhD of biomedical engineering, Material and Energy Research Center (MERC), Karaj, Iran


  • Introduction: Hyperthermia means a rise in temperature. Cancer cells are more sensitive to heat than healthy cells. Studies show that applying temperatures above 45°c due to protein binding directly leads to cell death. Today, magnetic nanoparticles are used to create this heat. Nano- particles with optical properties and different sizes express new methods for thermal treatments. Which can be used to use gold nanotubes. Magnetic nanoscale materials used for heat transfer exhibit magnetic properties.one of the important points about nanoparticles that are usable in medical applications are that the size and distribution of them are narrow. Magnetic nanoparticles should have appropriate shape and size for target tumors.
  • Methods: The magnetic nanoparticles have a low resistance to the magnetic field and show reaction in it. Heat in the human body is constantly changing due to the blood flow, and for this reason increasing the temperature can destroy the cancer cells is a difficult process. The advantage of this method is that even with the application of the weakest magnetic field, the necessary heat of nanoparticles can be provided to destroy cancer cells.
  • Results: The loading of anticancer drugs on magnetic nanoparticles has an important role in enhancing the function of the drug and destroying cancer cells. also the results show that by the alternate enforcement of magnetic field on nanoparticles that are outside of the patient's body, the temperature of nanoparticles and the whole tissue increases up so that the cancer cells are killed and by continuing the alternate enforcement of magnetic field, these nanoparticles find a para-magnetic feature and they don't produce heat anymore. therefore thus the healthy cells which are in the tissue won't face any damage, while the cancer cells will vanish completely.
  • Conclusion: Any study about nanoparticles, as well as the clarification of their functional mechanisms, will help in the design of new anticancer nanomaterials. Nano composites that allow the amount of cytotoxic drugs to be reduced and also decrease the resistance of cancer cells to drugs.
  • Keywords: drug delivery, magnetic particles, cancer