1. 1- Science faculty, Department of Biology, Central Tehran Branch, Islamic Azad University.
Cancer immune therapy is one of the newest and effective ways of treating cancer. cancer therapy is commonly used either alone or as complementary therapies, along with surgery, chemotherapy and radiotherapy. cancer immunotherapy take place in two ways; active and inactive. in active form, immune system recognizes the cancer cell and fight them back while in inactive form physicians supply modified immune system components such as antibodies to restrict cancer cells. with increased understanding of the immune system, small molecules, peptides, recombinant antibodies, vaccines, and cellular therapies are used to treat cancer.
Immunotherapies do not yet represent a panacea in cancer therapy since only a minor subset of some cancers respond to some of these treatments, and it is difficult or impossible to determine precisely who will benefit.
The immune system has the ability to defend the body against pathogens and cancer. one of the barriers for immune system to fight cancer is the capability of cancer cells to produce immunosuppressive cytokines such as tgf-beta. as a result, a number of therapeutic strategies have been developed to re-activating the immune system in cancer patients. as a result, immunotherapy is one the promising strategies in cancer treatment and requires a series of researches and developments.
• prevent the cancer from recurring
• destroy any cancer cells which are still in the body after other treatments have ended
• stop a tumor from growing or spreading