3D Bioprinting of Human Stem Cells for Neural Tissue Modeling and Disease Research (Review)
Animal models are widely used for disease modeling and drug discovery, but they ...Read more
3D Cellular Models and Human Organoids: Bridging Genetic Research and Precision Medicine (Review)
The modeling of genetic disorders remains a significant challenge in biomedical ...Read more
4T1 derived exosomes enriched with miR-375 reduce 4T1 cells proliferation and induce apoptosis (Research Paper)
Treatment of triple negative breast cancer (TNBC) is challenging due to lack of ...Read more
A review of hemolytic anemia associated with glucose-6-phosphate dehydrogenase deficiency caused by the antibiotic (Review)
Chloramphenicol and its derivatives (CAPs) are a class of bacteriostatic antibio...Read more
A Bioactive Hydrogel Based on Crocin and Chitosan: Physicochemical Properties, Antibacterial Activity, and Skin Tissue Repair Potential (Research Paper)
Hydrogels are cross-linked networks of hydrophilic polymers capable of absorbing...Read more
A Brief Review of Salmonellosis (Review)
Salmonellosis is one of the most common foodborne infections affecting humans an...Read more
A Comparison of the Biomechanical Characteristics of Cancer Cells and the Effect of Scaffold Mechanical Conditions on the Cellular Behavior (Review)
Cancer is one of the most frequent pathologies causing death in all parts of the...Read more
A Comprehensive Review of Helicobacter heilmannii-Induced Gastric Carcinogenesis in Companion Animal and the Therapeutic Potential of Silver Nanoparticles(AgNPs) (Review)
Helicobacter heilmannii, a member of the non-Helicobacter pylori (NHPH) group, h...Read more
A Comprehensive Review of Human Herpesviruses (Review)
Introduction: Human herpesviruses (HHVs), including HSV-1, HSV-2, VZV, EBV,...Read more
A Critical Review of the Role of Taboo and Social Stigma in the Perpetuation of Violence against Women (Review)
Violence against women remains one of the most persistent and universal forms of...Read more
A Double Dissociation in Oscillatory Control of Attention: Causal Mechanisms of Parietal Alpha and Prefrontal Slow Rhythms (Review)
Selective attention is fundamental to perception and cognition, allowing brain t...Read more
A Meta-Analysis of the Radiotherapy Impact on Cardiac Magnetic Resonance Imaging Findings (Review)
Recent advances in cancer treatment have significantly improved survival rates; ...Read more
A Multifunctional Nanocarrier Platform Based on Zinc–Amine–Graphene Oxide Functionalized Mesoporous Silica for Targeted Breast Cancer Therapy (Research Paper)
Breast cancer continues to be one of the most significant causes of cancer-relat...Read more
A Multimodal AI Framework for the Early Identification of Pancreatic PaNET Cancer: Combining Biomarkers, Genetic Predisposition, and Radiological Data (Review)
Pancreatic neuroendocrine tumors (PanNETs) are rare but clinically significant n...Read more
A Narrative Review: Lipoprotein(a) and Its Role in Atherosclerosis and Thrombosis (Review)
Apolipoprotein A (ApoA) is a major protein component of high-density lipoprotein...Read more
A network-based approach to identify hub genes in Huntington's disease (Research Paper)
Huntington's disease (HD) is a rare neurodegenerative disease characterized by p...Read more
A new study of the effect of the gene therapy (SMN2 gene) for ALS and SMA (Spinal Muscular Atrophy) (Review)
SMA is the clinical classified into four phenotypes on the basis of age of onset...Read more
A Novel Approach in HPV Management: Precise Genotyping via Hybrid PCR and Targeted Therapy Using CRISPR-Cas Systems (Research Paper)
Human papillomavirus (HPV) is one of the most prevalent sexually transmitted inf...Read more
A Reproducible Multi-Compound Network-Pharmacology Pipeline Identifies Hub Targets for Saffron Bioactives in Breast Carcinoma (Research Paper)
Multi-component natural products challenge single-target paradigms in oncology. ...Read more
A Review of Electrochemical Biosensors in Disease and Cancer Detection (Review)
Introduction: According to Professor Marshal Marinker, illness can be defined as...Read more
A review of novel combination treatments in Methicillin-resistant Staphylococcus aureus (MRSA) biofilm (Review)
Methicillin-resistant Staphylococcus aureus (MRSA) is a dangerous infection resp...Read more
A Review of Targeted Mutagenesis and Its Types (Review)
This type of mutagenesis is the process of creating specific changes in the stru...Read more
A Review of the Effects of Probiotics on Antioxidant Mechanisms in Improving Cognitive Function and Memory Disorders (Review)
Cognitive impairments resulting from oxidative stress and chronic neuroinflammat...Read more
A Review on the Application of Stem Cell-Seeded Silk Fibroin Scaffolds for Dermal Regeneration (Review)
The reconstruction of extensive skin defects remains a significant clinical chal...Read more
A Review on the Genes Involved in the Pathogenicity of Gram-Negative Bacteria Causing Bacteremia in Hospitalized Children (Review)
Bacteremia, the presence of viable bacteria in the bloodstream, represents a cri...Read more
A Review on the Properties of Zein and Sodium Caseinate in the Treatment of Ovarian cancer (Review)
Ovarian cancer is one of the most lethal malignancies of the female reproductive...Read more
A study of the effect of the 3D bioprinting, microfluidic in cardiac tissue engineering (Research Paper)
Cardiovascular diseases (CVDs) have been recognized as a major concern for globa...Read more
A Supervised Contrastive Learning Approach for ECG Label Noise Learning (Review)
With the widespread use of wearable devices, it has become increasingly easy to ...Read more
A Systematic Review of Antibiotic Resistance Patterns in Vaginal Lactobacillus Strains with Probiotic Potential (Review)
Antibiotic resistance is recognized as one of the most pressing global health ch...Read more
A Systematic Review of Deep Transfer Learning for Detecting Diabetic Macular Edema from OCT Images (Review)
Diabetic macular edema (DME) is a leading cause of vision loss in diabetic patie...Read more
A Systematic Review of Evidence on the Triangular Relationship between Nutrition, Mental Health, and Biological Markers in Students and the Development of Innovative School Health Planning Models (Review)
Nutrition is one of the fundamental determinants of students’ physical, psycho...Read more
A Systematic Review of HLA-DRB1*15:01 and Non-HLA Genetic Risk Factors Associated with MRI Lesion Burden in Relapsing-Remitting Multiple Sclerosis Patients (Review)
Multiple sclerosis (MS) is a chronic autoimmune disorder of the central nervous ...Read more
A Systematic Review of the Physiological and Psychological Mechanisms Linking Ultra-Processed Food Consumption to Adverse Health Outcomes (Review)
The global rise in ultra-processed food (UPF) consumption, driven by factors lik...Read more
A Systematic Review of U-Net Based Deep Learning for Glioblastoma Segmentation in Brain MRI (Review)
Accurate segmentation of glioblastoma subregions in brain MRI is critical for pr...Read more
Activated PI3K Delta Syndrome (APDS) (Review)
APDS is a primary immunodeficiency disorder caused by genetic mutations affectin...Read more
Active Minds in the Age of AI: Student Engagement in Medical Education (Review)
Student engagement is widely recognized as a cornerstone of effective medical ed...Read more
Adenoviral Vectors in Gene Therapy: The Future of Genetic Medicine (Review)
Gene therapy represents a transformative frontier in modern medicine, offering t...Read more
Advancements and Challenges of CRISPR-Cas9 Technology: Emphasis on Emerging Genome Editing Strategies and Delivery Platforms (Review)
CRISPR-Cas9 has emerged as one of the most transformative tools in genetic engin...Read more
Advances and Challenges in Women’s and Reproductive Health Informatics: A Global Perspective (Research Paper)
Women’s and reproductive health continues to face global challenges, including...Read more
Advances in Flow Cytometry Methods for Rapid Diagnosis of Escherichia coli: A Review and Comparative Analysis (Review)
Escherichia coli (*E. coli*) is a gram-negative bacterium with diverse strains, ...Read more
Advances in L-Asparaginase Therapy: Engineering Protease Resistance and Enhancing Stability for Pediatric Leukemia Treatment (Review)
Abstract: L-Asparaginase is a key enzyme in the treatment of pediatric acute lym...Read more
Advances in Stem Cell–Based Therapies for Regenerative Medicine: Opportunities and Challenges (Review)
Regenerative medicine seeks to restore damaged tissues and organs, offering solu...Read more
Advances in Tissue Engineering and Mesenchymal Stem Cells for Bone and Cartilage Regeneration: A Systematic Review of Recent Progress (2018-2025) (Review)
Bone and cartilage defects pose significant clinical challenges due to limited s...Read more
Aerobic Exercise and Wheat Supplementation Attenuate Methamphetamine-Induced Neuroinflammation in Male Rats (Research Paper)
Methamphetamine (METH) abuse is a global public health challenge that induces pr...Read more
Aerobic Exercise and Wheat Supplementation Synergistically Reduce Pro-Inflammatory Cytokines during Methamphetamine Withdrawal in Male Rats (Research Paper)
Methamphetamine (METH) misuse induces robust neuroinflammation. Exercise and die...Read more
Aflatoxin and its detoxification in food and feed (Review)
Mycotoxins are toxic secondary metabolites mainly produced by filamentous fungi ...Read more
Age-Stratified Evaluation of Common Polymorphisms in Thalassemia Among the Iranian Population: A Genomic Perspective (Research paper) (Research Paper)
Thalassemia refers to a genetically heterogeneous group of inherited hemoglobino...Read more
AI-Assisted cfDNA Fragmentomics for Ultra-Early Multi-Cancer Detection: A Systematic Review (Review)
Early detection of cancer remains the most effective strategy to improve surviva...Read more
AI-Driven EMG Signal Profiling of Facial Muscles for Smart Detection of Dental Malocclusion During Full Occlusion (Research Paper)
Occlusion refers to the alignment of the upper and lower teeth during contact. W...Read more
AI-Driven Microbiome Innovations (2025 Perspective) (Review)
The human microbiome has evolved from a concept in microbial ecology to a pivota...Read more
AI-Driven Prediction of Patient Responses to mRNA Vaccines and Immunotherapy Using Genomic Data (Review)
Messenger RNA (mRNA) vaccines represent one of the most significant innovations ...Read more
AI-Driven Radiogenomics and microRNA Biomarkers for Predicting Radiation Therapy Response in Non-Small Cell Lung Cancer: A Comprehensive Review (Review)
Non-small cell lung cancer (NSCLC) accounts for the majority of lung cancer case...Read more
AI-Guided Design, Docking, and ADMET Profiling of Novel HDAC2 Inhibitors for Cutaneous T-Cell Lymphoma Therapy (Research Paper)
Cutaneous T-cell lymphoma (CTCL) is a rare but challenging non-Hodgkin lymphoma ...Read more
Alamandine Mitigates Inflammation and Oxidative Stress in OVA-Induced Asthma: A Novel Therapeutic Approach (Research Paper)
Asthma is a chronic disease with eosinophilic inflammation and oxidative damages...Read more
AMG232 Inhibits Angiogenesis in Multiple Myeloma Cells via Downregulation of VEGF/VEGFR2 Expression and Suppressing Migration in HUVECs (Research Paper)
Angiogenesis markedly affects the progression and severity of multiple myeloma (...Read more
An Integrative analysis of the Biomechanical effect of PLA/Collagen Scaffold containing Bioactive Nano particles in bone tissue regeneration (Review)
Engineering of bone tissue has become a promising therapeutic intervention to tr...Read more
An overiew diagnosis ,teartment and prevention of Malt Fever (Review)
Malt fever is one of the most important common diseases of humans and animals an...Read more
An overview of breast cancer prevention, diagnosis and treatment (Review)
Breast cancer is one of the most common types of cancer in women worldwide, and ...Read more
An overview of the Advancements in Acute Myeloid Leukaemia (AML) treatments with the potential of CAR-NK cells immunotherapy (Review)
Introduction: AML is the short form of Acute Myeloid Leukaemia cancer , which is...Read more
Analysis of common polymorphisms of Acute Myeloid Leukemia (AML) in the Iranian genome profile and evaluation of side effects of indigenous Iranian medicines (Research Paper)
Acute Myeloid leukemia (AML) is a heterogeneous hematological malignancy charact...Read more
Analysis of immunogenicity and purification methods in conjugated polysaccharide vaccines: a new approach in fighting pathogenic bacteria (Review)
Over the past two decades, glycoconjugate vaccines have emerged as a powerful to...Read more
Analysis of the Association of Genetic and Epigenetic Polymorphisms in Sarcoma Cancer (Research Paper)
Sarcomas are among the rarest cancers, constituting only a small fraction of mal...Read more
Anti-aging natural supplements: the main players in promoting healthy lifespan (Review)
Aging is an inevitable process marked by physiological decline and increased ris...Read more
Anti-fungal Activity of Terbinafine-Loaded Lipid Nanostructures on Dermatophyte Species Isolated from Animals (Research Paper)
A group of filamentous fungi known as dermatophytes are responsible for causing ...Read more
Anti-inflammatory and chondroprotective activity of a small-molecule-loaded nanoparticle/hydrogel system (Research Paper)
Cartilage lesions typically cause pain and disability, often necessitating medic...Read more
Anti-Inflammatory Effects of Artemisia fragrans Essential Oil Through iNOS Gene Suppression in Activated Macrophages: A Molecular Insight (Research Paper)
Chronic inflammation is a key contributor to various diseases such as cancer, ca...Read more
Anti-migration and Apoptotic Induction Effects of Froriepia subpinnata Extract -Functionalized Silver Oxide (Ag2O) Nanoparticles on AGS gasteric cancer cells via Modulation of miR-34a and EGFR gene (Research Paper)
Froriepia subpinnata (Ledeb.) Baill. is a traditional Iranian medicinal herb wit...Read more
Anti-Needlestick IV Cannula with Phlebitis Detection Capability (Research Paper)
Peripheral intravenous catheters (PIVCs) are indispensable in modern care but ar...Read more
Antibacterial and Antioxidant Bioactivity of Electrospun PVA Mats Loaded with Hydroalcoholic Extract of Iranian Propolis (Research Paper)
Free radicals are natural metabolites produced in living cells and are known to ...Read more
Antibacterial Effects of Nanoemulsions Containing Extract and Essential Oil of Juniperus polycarpos (Research Paper)
Juniperus polycarpos is a native species of the Iranian plateau, known for the w...Read more
Antibiofilm potential of postbiotics in improving human health (Review)
Biofilms are sessile microbial consortia embedded in a self-produced extracellul...Read more
Antibiotic Resistance and Its Impact on Infection Control: A Microbiological Review of Therapeutic Failures (Review)
Abstract Antibiotic resistance isn’t just a medical buzzword—it’s a creep...Read more
Antibiotic Resistance Mechanisms in Acinetobacter baumannii: A Growing Threat to Healthcare Systems (Review)
Acinetobacter baumannii is included in the Moraxellaceae family [4] It is an a...Read more
Antibiotic Resistance Mechanisms in Acinetobacter baumannii: A Growing Threat to Healthcare Systems Worldwide (Review)
Acinetobacter baumannii is included in the Moraxellaceae family [4] It is an a...Read more
Antimicrobial Effects of Green Synthesized Nanoparticles with Rosemary Extract (Review)
Escalating antimicrobial resistance necessitates alternatives or adjuvants to co...Read more
Antimicrobial Effects of Steroidal and Non-Steroidal Drugs Used in Asthma on Clinical Bacterial Isolates (Research Paper)
Introduction: Asthma is a multifactorial inflammatory disease of the airways, of...Read more
Antimicrobial Peptides as New Treatments for Biofilm-Associated Infections: A Meta-Analysis of Efficacy in Models of Klebsiella pneumoniae and Acinetobacter baumannii (Review)
In the area of clinical microbiology, infections that affect biofilms pose chall...Read more
Antioxidant and anticancer potential of methanolic rhizome extract of Polygonum bistorta L. against HT-29 colon cancer cells (Research Paper)
Colorectal cancer is one of the most common cancers worldwide and is still a lea...Read more
Antioxidant, anti-amylase, anti-lipase, and efficiency of Satureja fatty acid on the anti-inflammatory parameters in lipopolysaccharide-stimulated macrophage (Research Paper)
Introduction: Satureja is a genus in the Lamiaceae family, consisting of approxi...Read more
Antioxidant, anti-amylase, anti-lipase, and hypoglycaemic efficacy of Satureja essential oil (Research Paper)
Introduction: Satureja is a genus in the Lamiaceae family, comprising around 200...Read more
APC Mutation Type as a Prognostic Indicator for Tumor Stage in a Iranian Familial Colorectal Cancer Cohort (Research Paper)
Germline mutations in the Adenomatous Polyposis Coli (APC) gene are a establishe...Read more
Apoptosis-Targeted Nanotherapy in Cervical Cancer (Review)
Cervical cancer is one of the most common cancers in women worldwide, with over ...Read more
Application of Artificial Intelligence Algorithms in Interpreting Psychiatric Biomarkers: A Comprehensive Review (Review)
The convergence of artificial intelligence (AI) and psychiatric biomarker resear...Read more
Application of decellularized bone matrix as a bioscaffold in bone tissue engineering (Review)
Autologous bone grafts are commonly used as the gold standard to repair and rege...Read more
Application of nanotechnology-based transdermal patches in targeted drug delivery for cancer treatment (Review)
Cancer, as one of the leading causes of death in the world, especially in develo...Read more
Application of Stem Cells in Repairing Damaged Cardiac Tissue (Review)
The human body comprises more than 200 distinct cell types, organized into tissu...Read more
Application of tannic acid hydrogels in biomedical engineering (Review)
Polyphenols are a class of naturally occurring organic compounds widely distribu...Read more
Applications of Artificial Intelligence in Cancer Diagnosis and Treatment (Review)
Cancer remains one of the leading causes of death worldwide, and early detection...Read more
Applications of Artificial Intelligence in Drug Personalization (Review)
The traditional "one-size-fits-all" model of medicine often leads to v...Read more
Applications of Artificial Intelligence in Medical Biotechnology (Review)
Artificial Intelligence (AI) has become a transformative force in medical biotec...Read more
Applications of Artificial Intelligence in Medical Genetics (Review)
Artificial Intelligence (AI) is revolutionizing medical genetics by enabling rap...Read more
Applications of Artificial Intelligence in Next-Generation Sequencing (Review)
Next-generation sequencing (NGS) technologies have revolutionized our understand...Read more
Applications of Artificial Intelligence in the Management of Hypertension in the Elderly (Review)
Hypertension remains a persistent public health challenge due to its high preval...Read more
Applications of Nanotechnology in Modern Medicine (Review)
Nanotechnology,the manipulation of matter at the atomic and molecular scale (app...Read more
Aptamer-Based Approaches in Leukemia: A Paradigm Shift in Targeted Therapy” Running title: Aptamers in Leukemia Diagnosis and Treatment (Review)
Aptamers, which are short, single-stranded DNA or RNA molecules, have emerged as...Read more
Artificial Intelligence and Machine Learning in Precision Medicine: Opportunities, Challenges, and Future Perspectives (Review)
Abstract (with Introduction & Objectives): Precision medicine is an emergin...Read more
Artificial Intelligence and Predictive Genomics: A New Era in Personalized Diagnosis and Therapy (Review)
Predictive genomics, integrated with artificial intelligence (AI), represents a ...Read more
Artificial Intelligence and women's health: A Systematic Review (Review)
Artificial Intelligence (AI) has played a significant role in transforming obste...Read more
Artificial Intelligence in Biomedical Science: From Predicting Genetic Mutations to Designing Personalized Treatments (Research Paper)
Artificial intelligence has rapidly penetrated the fields of medicine and biomed...Read more
Artificial Intelligence in Breast Cancer Care: Enhancing Diagnosis, Prognosis, and Personalized Treatment (Review)
Breast cancer (BC) is a significant cause of cancer-related mortality in women w...Read more
Artificial Intelligence in Cancer Diagnosis : Advances and its role in biotechnology Medicine (Review)
Introduction Cancer is a complex disease where timely diagnosis plays a pivotal...Read more
Artificial Intelligence in Cancer Diagnosis: Advances and Its Role in Biotechnology Medicine (Review)
Abstract Timely and accurate diagnosis is critical in cancer management, direct...Read more
Artificial Intelligence in Glioblastoma: Emerging Approaches for Diagnosis, Therapeutic Decision-Making, and Response Prediction (Review)
Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor, charac...Read more
Artificial Intelligence in Veterinary Virology: Genomic Surveillance, Pathogenesis Modeling, and Predictive Epidemiology (Review)
The rise in complexity related to viral diseases of livestock is creating a high...Read more
Artificial Intelligence-Driven Smart Nanosystems: A Revolution in Personalized Medicine with Gene Delivery and Drug Delivery. (Review)
Personalized medicine has revolutionized biomedical sciences by tailoring treatm...Read more
Aspergillus Pectinases: A Comparative Study of Natural Component Profiles and Their Effects on Tumor Cell Metabolism (Review)
Introduction Pectinases are a group of enzymes that guarantee the hydrolytic de...Read more
Assessment of Common Polymorphisms in CML within the Iranian Genomic Profile: Age of Onset Stratification and Drug Selection (Research Paper)
In this study, we investigated common genetic polymorphisms in Iranian patients ...Read more
Assessment of overall survival and disease free survival of stage 1 endometrial cancer patients referred to the department of clinical oncology of Golestan Hospital in Ahvaz between 1395 and 1398 (Research Paper)
The final results of the PORTEC-3 trial demonstrated that the combination of che...Read more
Assessment of Quality of Life Among Women with Osteoarthritis in Gilan Province (Research Paper)
Osteoarthritis is among the most prevalent chronic and progressive joint disorde...Read more
Assessment of Serum Troponin Levels and Their Clinical Correlates in Hospitalized COVID-19 Patients: A Retrospective Study from Ardabil, Iran (Research Paper)
Coronavirus disease 2019 (COVID-19) has emerged as a global health crisis, with ...Read more
Assessment of TNF-α Protein Levels in Intestinal Tissue of Patients with Inflammatory Bowel Disease (Research Paper)
Inflammatory bowel disease (IBD) has been developing worldwide as a health probl...Read more
Association between GLUT4 Gene Variants and Hemoglobin A1c Levels in Type 2 Diabetes Patients (Review)
Type 2 diabetes (T2D) is a growing global health concern, with its prevalence ri...Read more
Association of Atorvastatin and Nuclear Factor Kappa-Light-Chain Enhancer of Activated B cells (NF-κB) in Type 2 Diabetes Mellitus Disease (Review)
Type 2 Diabetes Mellitus (T2DM) is an inflammatory disease caused by the inabili...Read more
Association of Non-Alcoholic Fatty Liver Disease (NAFLD) and Hypothyroidism in Iranian Adolescents: The Potential Role of Artificial Intelligence in Diagnosis (Research Paper)
Non-alcoholic fatty liver disease (NAFLD) is increasingly recognized as a major ...Read more
Association of Rare SNPs in Vitamin B12 Metabolism Genes with Gastric Cancer Risk in a Nutritionally Deficient Population (Research Paper)
This study investigates the association of rare SNPs in vitamin B12 metabolism g...Read more
Associations of Lactose Intolerance-Related SNPs in the LCT Gene and Colorectal Cancer risk (Research Paper)
Colorectal cancer (CRC) is the third most common cancer and the second leading c...Read more
Augmented Intelligence in the Operating Room: A Real-Time AI Framework for Surgical Precision, Error Reduction, and Global Scalability (Review)
Intraoperative errors remain a significant cause of surgical morbidity and morta...Read more
Bacterial Antigens in Vaccine Technology (Research Paper)
The surface of cells is enveloped by a compact coating of glycans, referred to a...Read more
Benefits of immunotherapy in the treatment of pediatric acute lymphoblastic leukemia (Review)
Abstract: Acute lymphoblastic leukemia (ALL) is a subtype of leukemia that is c...Read more
beta-thalassemia gene therapy (Review)
Beta-thalassemia is an inherited disorder caused by reduced or absent β-globin ...Read more
Bioengineered Chitosan-Moringa Hydrogels: In Vitro Evaluation of Cell Viability and Regenerative Potential for Wound Care (Research Paper)
Hydrogels represent a promising alternative to traditional wound dressings, offe...Read more
Biogenic Silver Nanoparticles Synthesized by Lactobacillus casei: Implication to Anticancer Properties (Research Paper)
Breast cancer remains one of the most prevalent malignancies globally with over ...Read more
Bioinformatics Analysis of Circulating Tumor Cells in Pancreatic Ductal Adenocarcinoma Identifies LAMA2 and COMP as Potential Biomarkers in Metastatic Progression (Research Paper)
Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-re...Read more
Bioinformatics Analysis of Promoter Region Polymorphisms in the BRCA1 Gene among Patients with Metastatic Breast Cancer (Review)
Breast cancer remains among the most prevalent malignancies worldwide, with over...Read more
Bioinformatics Identification of FN1 as a Key Hub Gene in DCIS-to-IDC Progression (Research Paper)
Ductal carcinoma in situ (DCIS) and invasive ductal carcinoma (IDC) represent di...Read more
Bioinformatics of Leukemia (Research Paper)
As an aggressive hematologic malignancy, acute myeloid leukemia (AML) is charact...Read more
Bioinformatics Study of the P4G Mutation Effect on Tumor Suppressor p53 (Review)
The tumor suppressor protein p53, known as the "guardian of the genome,&quo...Read more
Bioinformatics-Driven Design and Molecular Docking of a Multiepitope Vaccine Targeting Helicobacter felis (Research Paper)
Helicobacter felis (GCF_000200595.1) is a Gram-negative, spiral-shaped bacterium...Read more
Biological Effects Evaluation of PEG-BBN Peptide Labeled with Indium-113m Radionuclide on Cancer Cells Expressing (GRP) receptor (Research Paper)
One of the well-known receptors that is overexpressed in human prostate cancer (...Read more
Biological superabsorbent hydrogels based on Curdlan to control infectious wounds (Review)
Wounds caused by disease, trauma and accidents are a common clinical problem. So...Read more
Biomarkers in Medicine: New Findings Reshape Patient Treatment Protocols (Review)
Biomarkers in medicine have dramatically transformed how doctors diagnose, treat...Read more
Biomedicine and neuroscience: synergy for understanding and treating neurological diseases, an abstract review (Review)
The convergence of biomedicine and neuroscience marks a pivotal moment in our qu...Read more
Bioremediation of VOCs and DOC: Using Algae-Based Systems (Review)
The influence of Dissolved organic carbon (DOC) and Volatile Organic Compounds (...Read more
Bourgeonal and Its Role in Human Sperm Chemotaxis (Review)
Bourgeonal is an aromatic aldehyde with the chemical formula C₁₁H₁₂O and...Read more
Breast Cancer Prevention Genetics Counseling (Review)
Studies have shown that approximately 10% of breast cancer cases are attributed ...Read more
Caecal and Colon Rupture Due to Thyphoid Fever in A 22 Years Old Male, A Rare Complication: A Case Report (Research Paper)
Typhoid fever is an acute infection caused by Salmonella typhi, especially when ...Read more
Can cocoa modulate blood lipids in type 2 diabetes? (Review)
The risk of cardiovascular morbidity and mortality is higher in patients with di...Read more
Cancer immunotherapy with CAR-T and CAR-NK cells (Research Paper)
Immunotherapy based on engineered cells, particularly CAR-T and CAR-NK cells, ha...Read more
Cancer-Associated Fibroblasts in the Tumor Microenvironment: Heterogeneity, Plasticity, and Emerging Therapeutic Opportunities (Review)
The concept of the tumor microenvironment (TME), first introduced by Stephen Pag...Read more
Carbon Dots: Tiny Particles, Powerful Antimicrobial Effects (Research Paper)
Antibiotic resistance has become one of the most pressing global health challeng...Read more
Cardiovascular and all-cause mortality outcomes of adrenalectomy versus medical treatment in primary aldosteronism: an umbrella review (Review)
Primary aldosteronism (PA) is now recognized as the most prevalent form of secon...Read more
Cell Culture in Cancer Drug Discovery and Development (Review) (Review)
The process of drug discovery and development is a complex, expensive, and time-...Read more
Cell-Based Therapy Using Menstrual Blood-Derived Mesenchymal Stem Cells for the Restoration of Ovarian Function in PCOS: An In Vivo Study (Research Paper)
Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine disorder characterized...Read more
Challenges and Advances in the Diagnosis and Management of Clostridioides difficile and Klebsiella pneumoniae Infections and colonization: A Narrative Review (Review)
Public health faces a global threat posed by Clostridioides difficile (CDI) and ...Read more
Chronic pain management in pediatrics : A Narrative Review (Review)
The anticipation and effective management of pain in pediatric patients are an e...Read more
Circulating MiR-1 Expression in NSCLC patients: Possible Correlation with Clinico-pathologic Characteristics and Lung Cancer Detection (Research Paper)
Circulating microRNAs have been recognized as promising biomarkers for the detec...Read more
Classification of active and non-active multiple sclerosis plaques using mp-MRI based on Radiomics (Review)
Multiple sclerosis (MS) is a chronic autoimmune disease characterized by the imm...Read more
Clear Cell Renal Cell Carcinoma in the Modern Era: A Review of Evolving Targeted and Combination Therapies from 2020 to 2025 (Review)
Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell...Read more
Climate Change and Its Impact on Human Health (Review)
Climate change is increasingly recognized as a major global health challenge. Ri...Read more
Clinical Application of Psychobiotics in Neuropsychiatric Disorders: Advancing Therapeutics via the Microbiota–Gut–Brain Axis (Review)
Psychobiotics represent an emerging class of probiotics with distinct neuroactiv...Read more
Clinical efficacy and safety of low-dose oral minoxidil versus topical solution in the improvement of androgenetic alopecia: A randomized controlled trial (Research Paper)
Androgenetic alopecia (AGA) is the most common form of progressive hair loss wit...Read more
Clinical significance of mitochondrial genome-derived circRNA hsa_circ_0002363 in triple negative breast cancer (Research Paper)
One kind of breast cancer that spreads very quickly is triple-negative breast ca...Read more
Clinical Significance of Reduced FAM181B Expression in Papillary Thyroid Carcinoma (Research Paper)
Papillary thyroid carcinoma (PTC) is classified as a well-differentiated cancer ...Read more
Cloning and expression of PLC-Darpin fusion protein in a prokaryotic host as an immunotoxin putative candidate against breast cancer (Research Paper)
Cancer is one of the genetic diseases, breast cancer (BC) is one of the commones...Read more
Combining Adhesion Molecule and Immune Checkpoint Targeting in TNBC: Mechanisms and Treatment Potential (Review)
Cancer remains one of the leading causes of mortality worldwide and is strongly ...Read more
Combining Targeted Therapy and Immunotherapy in Cancer: Opportunities and Challenges (Review)
Cancer treatment has evolved with the development of targeted therapies and immu...Read more
Common Polymorphisms Associated with Beta-Thalassemia Minor (Research Paper)
Minor thalassemia is one of the most common genetic blood disorders worldwide, ...Read more
common polymorphisms in thalassemia disease (Research Paper)
Here we are going to investigate the pharmacogenetics of thalassemia major by us...Read more
Communication between cells in the microenvironment of atherosclerotic plaques (Review)
Atherosclerosis develops as a result of numerous cellular and molecular activiti...Read more
Comparative Effectiveness of Pharmacological versus Psychotherapeutic Interventions for Depression in Patients with Endocrine Disorders: A Review (Review)
The bidirectional association between endocrine disorders and depression offer u...Read more
Comparative Evaluation of Barberry-Derived Honey and Commercial Honey on HT-29 Colorectal Cancer Cells: In Vitro Anticancer Effects (Research Paper)
Colorectal cancer (CRC) remains one of the leading causes of cancer-related mort...Read more
Comparative GO Enrichment of Crocin, Picrocrocin, and Kaempferol Targets (Research Paper)
Natural products often act via multi-target mechanisms. We compared the function...Read more
Comparative In Silico Assessment of G6PD Variants G163S and R459L Reveals Diagnostic Value of Pathogenicity Prediction Tools (Research Paper)
Introduction Glucose-6-phosphate dehydrogenase (G6PD) is a critical enzyme invo...Read more
Comparative Review of Native, Hydrogel, and 3D Forms of Amniotic Membrane in Diabetic Wound Healing (Review)
Diabetic wounds present a significant global health burden due to their chronic ...Read more
Comparative Study of Antibiotic Resistance Patterns in Acinetobacter baumannii Isolates from Intensive Care Unit and Non-Intensive Care Unit Wards in a Hospital in Tehran, 2025 (Research Paper)
Acinetobacter baumannii is an important cause of nosocomial infections and a hig...Read more
Comparative Study of the Anticancer Effects of Anethum graveolens and Alcea glabrata on Human Gastric Adenocarcinoma Cell Line (AGS): Induction of Apoptosis and Downregulation of HER2 Expression (Research Paper)
Gastric cancer is the fifth most common cancer worldwide and a leading cause of ...Read more
Comparative study of the antimicrobial effects of ethanolic and acetonic extracts of Sinapis alba seed and Citrus sinensis peel against Staphylococcus aureus and Pseudomonas aeruginosa in a burn infection model (Research Paper)
The growing problem of antibiotic resistance and the limited success of common t...Read more
Comparison of the Effectiveness of Empagliflozin and Metformin, in Controlling Diabetes in Patients with Post-Transplant Diabetes Mellitus(PTDM) (Research Paper)
Solid organ transplantation is considered a life-saving solution for end-stage p...Read more
Comparison of the effectiveness of ginger and chamomile in the severity of nausea and vomiting in patients undergoing chemotherapy; systematic review (Review)
Nausea and vomiting is the most common and annoying complication of chemotherapy...Read more
Comparison of the effects of eight weeks of aerobic and polarized training on pulmonary function, inflammatory markers, and vascular endothelial growth factor in active young girls (Research Paper)
Regular physical activity is recognized as a non-pharmacological intervention th...Read more
Computational and Experimental Design of a Multi-Epitope Vaccine Based on PcrV and OmpE of Pseudomonas aeruginosa Using Immunoinformatics (Research Paper)
Pseudomonas aeruginosa is an opportunistic pathogen causing infections such as U...Read more
Computational Design of an MUC1-Targeted mRNA Vaccine for Colorectal Cancer: Population-Specific Optimization for Iranian HLA Alleles (Research Paper)
Colorectal cancer (CRC) ranks as the third most prevalent cancer globally, with ...Read more
Computational Modeling of Probiotic Effects on Blood Glucose: A Short-Term Dynamic Simulation (Review)
The global rise of type 2 diabetes (T2DM) underscores the need for innovative gl...Read more
Computational screening of artemisinin-based compounds as multi-target inhibitors of key atherogenic proteins (Research Paper)
Atherosclerosis is a progressive inflammatory disease caused by lipid dysregulat...Read more
Connection Between Stress, Neuroinflammation, and Irritable Bowel Syndrome: Positive Impact of Probiotic Therapy (Review)
Stress is a physiological response to environmental challenges, aimed at maintai...Read more
Conversational AI in Medical Training: A Narrative Review of ChatGPT’s Role in Standardized Patient Development (Review)
Standardized patients (SPs) are an essential pedagogical tool in medical educati...Read more
Correcting Excitotoxicity in Alzheimer's Disease: The Role of Exercise in Normalizing the D-serine/NMDAR Signaling Pathway (Review)
D-serine, a D-amino acid produced by the enzyme serine racemase (SR), is the pri...Read more
Correlation between diabetic complications: Predicting protein–protein interactions, drug-protein interactions, and molecular docking study (Research Paper)
Diabetic nephropathy, retinopathy, and neuropathy are interconnected microvascul...Read more
CRISPR in Medical Genetics: Clinical Applications and Challenges (Review)
CRISPR technologies have reshaped medical genetics by enabling precise correctio...Read more
CRISPR-Based Activation of Tumor Suppressor Genes: A Novel Strategy in Precision Cancer Therapy (Review)
Cancer is fundamentally a genetic disorder, arising from the activation of oncog...Read more
CRISPR-based Nano-biotechnology for Personalized Cancer Therapy (Review)
Cancer is a highly complex disease driven by genetic and molecular alterations, ...Read more
CRISPR-based nanobiosensors and gene delivery systems: Towards next-generation personalized medicine (Review)
The CRISPR Cas system has revolutionized genome editing and offers precise tools...Read more
CRISPR-based Rapid Diagnostics for Emerging Antifungal Resistance in Candida auris. (Review)
Invasive fungal infections have become a major public health challenge in the la...Read more
CRISPR-Cas Mechanisms Against Antibiotic-Resistant Bacteria: A Novel Approach (Review)
Recent studies show that the emergence of antibiotic-resistant bacterial strains...Read more
CRISPR-Cas Mechanisms Against Antibiotic-Resistant Bacteria: A Novel Strategy (Review)
Recent studies show that the emergence of antibiotic-resistant bacterial strains...Read more
CRISPR-Cas Systems in Combating Bacterial Infections: A Systematic Review of Therapeutic Potential and Limitations (Review)
The growing threat of antibiotic-resistant bacteria has highlighted the urgent n...Read more
CRISPR-Cas9 Applications in Cancer Immunotherapy: Recent Advances, Clinical Trials, and Translational Challenges (2020–2025) (Review)
CRISPR-Cas9 genome editing technology has rapidly become a cornerstone in modern...Read more
CRISPR-Cas9: Advances, Applications, and Future Directions in Biotechnology (Review)
The rapid evolution of gene-editing technologies over the past two decades has p...Read more
CRISPR-Mediated Silencing of Oncogenes: A Promising Frontier in Targeted Cancer Therapy (Review)
Cancer develops through a complex interaction of genetic and epigenetic alterati...Read more
CRISPR/Cas Technology: a promising player against bacterial infection and antibiotic resistance (Review)
The emergence of antimicrobial resistance (AMR) poses a significant threat to bo...Read more
Crocin Protects Against Beta-Amyloid Peptide-Induced Apoptosis in PC12 Cells Via the PI3 K Pathway (Research Paper)
Crocin is a known compound with the antioxidant and anti-inflammatory propertie...Read more
Current perspectives of Human Papillomavirus (HPV) infection and vaccination in cervical cancer (Review)
HPV is a member of the Papovaviridae family. It is a small, non-enveloped virus ...Read more
Cytokine-induced killer cells: new insights for therapy of hematologic malignancies (Review)
Cytokine-induced killer (CIK) cells are a novel subgroup of immune effectors, cl...Read more
Cytotoxic and apoptotic effect of curcumin- silver nanoparticles on MCF7 cell line (Research Paper)
Breast cancer is the most prevalent malignancy among women worldwide and remains...Read more
Cytotoxic Effects of Quercetin-Encapsulated PEG-PCL/Graphene Quantum Dot Nanoplatform on 5-FU-Resistant Gastric Cancer Cells (Research Paper)
Gastric cancer is a primary global health concern and remains one of the leading...Read more
Deciphering shared and distinct molecular mechanisms in pediatric and adult Systemic Lupus Erythematosus: A Comparative gene expression and pathway analysis (Research Paper)
Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease that manifest...Read more
Deep Learning for Cortical Lesion Detection in Ultra-High-Field MRI of Multiple Sclerosis Patients: A Systematic Review of Annotation Strategies and Performance Metrics (Review)
Cortical lesions (CLs) in multiple sclerosis (MS) are increasingly recognized as...Read more
Design and development of heparin-based Nano micelles for delivering amiodarone in the treatment of cardiac arrhythmias (Research Paper)
Amiodarone is a class III antiarrhythmic agent that inhibits the abnormal heart ...Read more
Design and Evaluation of a Novel Fusion Antigen for Diagnosing Human Strongyloidiasis: An Immunoinformatics Approach (Research Paper)
Strongyloidiasis, caused by Strongyloides stercoralis, remains a neglected tropi...Read more
Design and Fabrication of Mesenchymal Stem Cell-Derived Exosome-Based Drug Delivery System for Cancer-Related Applications (Research Paper)
Cancer is one of the leading causes of death worldwide, with nearly 19.3 million...Read more
Design and production of molecular detection kit (RT-PCR) for feline FIP virus through specific primer design (Review)
Feline Infectious Peritonitis (FIP) is one of the most fatal viral diseases in c...Read more
Design and Synthesis of a Novel Nanoparticle for Photothermal Therapy (Research Paper)
Cancer remains one of the leading causes of death worldwide. Traditional therapi...Read more
Design and Theoretical Formulation of a Latex Agglutination-Based Rapid Test Kit for C-Reactive Protein (CRP) Detection (Research Paper)
C-reactive protein (CRP) is a widely used biomarker for inflammation and infecti...Read more
Design of a Multi-Epitope Peptide Vaccine Against Glioblastoma Multiforme Targeting IL13Rα2: An Immuno-Informatics Approach (Research Paper)
Glioblastoma Multiforme (GBM) is the most aggressive primary brain tumor, notori...Read more
Design of a neuron- inspierd DNA walker for use in molecular genetics researches (Research Paper)
Introduction: DNA walkers are advanced biological nanomachines include precise a...Read more
Design, Production, and evaluation of recombinant fusion NIE/SsIR antigens for the diagnosis of human strongyloidiasis (Research Paper)
Strongyloidiasis is a neglected tropical disease caused by the intestinal nemato...Read more
Designing a personalized gene therapy pathway for AML based on the functional assessment of NPM1 and the elimination of mutagenic elements (Research Paper)
Cancers represent a diverse group of genetic and metabolic disorders characteriz...Read more
Detection of hybrid uropathogenic/diarrheagenic Escherichia coli strains among uropathogenic E. coli isolates in clinical isolates of Khorramabad city (Research Paper)
Urinary tract infection (UTI) is one of the most common bacterial diseases in hu...Read more
Detection of Merkel Cell Polyomavirus genome in Recreational Waters of Tehran (Research Paper)
Merkel cell polyomavirus is categorized as a member of the Polyomaviridae family...Read more
Development of PEGylated alginate-Moringa-Tetracycline Composite Hydrogels: Physicochemical Characterization and In Vitro Assessment of Biocompatibility for Wound Healing Applications (Research Paper)
Hydrogels, as three-dimensional hydrophilic polymeric systems, offer distinct ad...Read more
Diabetic Foot Ulcer Healing Using Maggot Therapy in Hospitalized Patients (Research Paper)
Introduction: Diabetic foot ulcer is a serious complication of diabetes that can...Read more
Diagnostic Accuracy of Convolutional Neural Networks Models for Early Detection of Multiple Sclerosis in MRI Images: A Systematic Review of Imaging-Based Clinical Applications (Review)
Early diagnosis of Multiple Sclerosis (MS) is critical for effective interventio...Read more
Diagnostic Accuracy of Ultrasound in Ectopic Pregnancy and Molar Pregnancy: A Comprehensive Review (Review)
Ectopic pregnancy and molar pregnancy are two types of abnormal pregnancies that...Read more
Diagnostic Potential of lncRNA AC073352.1 and YBX1 as Biomarkers for Breast Cancer Detection (Research Paper)
Breast cancer is a common cancer in women, often linked to reduced survival in a...Read more
Diagnostic Value of ELISA test in diagnosis of Brucellosis (Research Paper)
Background: Brucellosis is one of the most common zoonotic diseases in Iran, esp...Read more
Dietary Interventions, Gut Microbiota, and Neurobehavioral Outcomes: A Systematic Review (Review)
Chronic stress–induced anxiety, depression, and cognitive impairments are amon...Read more
Digital Health Platforms for Postmenopausal Women: Predictive Informatics to Manage Multimorbidity and Healthy Aging (Research Paper)
Women in postmenopausal and geriatric stages experience unique health risks, inc...Read more
Digital Twins in Medicine: Digital Simulation of Patients for Personalized Treatment (Review)
Originally developed in the engineering sector to precisely model physical syste...Read more
Diosmetin trough increase in the CA3 diameter of the hippocampus possessed antidepressant-like effect in mice: possible role of NMDA receptors (Research Paper)
The aim was to determine the role of NMDA receptors in the antidepressant-like e...Read more
Do Liberal Abortion Policies Always Lead to a Reduction in Abortion Rates? (Review)
Abortion remains one of the most complex social, legal, and ethical issues in co...Read more
Docking Simulation of Umbelliprenin as a Potential Lead Inhibitor against 5-Lipoxygenase Enzyme (Research Paper)
5-Lipoxygenase (5-LOX) is a key enzyme in the metabolism of unsaturated fatty ac...Read more
Drug Development Candidates Identification in Grade II Astrocytoma: A Systems Biology Approach (Research Paper)
Grade II astrocytomas are a subgroup of low-grade glioma that have slow growth b...Read more
Drug-Loaded Three-Dimensional Scaffolds: A Promising Strategy for Targeted Skin Cancer Therapy (Review)
Three-dimensional (3D) scaffolds have recently emerged as a promising and innova...Read more
Early Cancer Detection Using Artificial Intelligence: A Review of Current Approaches (Review)
Early detection of cancer significantly improves patient survival and treatment ...Read more
Early Cancer Detection Using Circulating Free DNA: A Non-Invasive Approach (Review)
Early detection of cancer is one of the most effective strategies to reduce mort...Read more
effect of hope therapy on the quality of life of elderly people with cancer (Research Paper)
Cancer is the third leading cause of death and one of the most important causes ...Read more
Effect of Microbiome on the Mood: A Meta-Analysis of Lactobacillus rhamnosus in Depression (Review)
The gut-brain axis is increasingly becoming an extremely promising area for find...Read more
Effect of nitrogen doping ratio on increasing the wavelength of carbon dots with optical/biological sensor application (Research Paper)
Higher concentrations with doping precursors, especially nitrogen compounds, alo...Read more
Effect of oral treatment of royal jelly on the expression of AXNA1 and AXNA2 genes in skin wound of male mice (Research Paper)
Wound healing is a complex biological process involving hemostasis, inflammation...Read more
Effect of the cyanobacterium Spirulina on acetaminophen-induced hepatic necrosis in adult male Syrian mice (Research Paper)
Acetaminophen (paracetamol) overdose is a leading cause of acute hepatic necrosi...Read more
Effective Use of Artificial Intelligence (AI) in Pre-Implantation Embryo Selection (Review)
The integration of artificial intelligence (AI) into pre-implantation embryo sel...Read more
Effectiveness of Pomegranate (Punica granatum) in Preventing Preeclampsia and Pregnancy Hypertension (Review)
Hypertensive disorders of pregnancy, particularly preeclampsia, affect approxima...Read more
Effectiveness of Problem-Based Learning in Undergraduate Medical Education: A Synthesis of Recent Review Evidence (Review)
Problem-based learning (PBL) is a student-centered pedagogical approach widely a...Read more
Effects of an Eight-Week Aerobic Exercise Intervention on Pulmonary Function Parameters, C-Reactive Protein, Creatine Phosphokinase, and Vascular Endothelial Growth Factor in Young Female Athletes: A Quasi-Experimental Study (Research Paper)
Regular physical activity is widely recognized as a non-pharmacological approach...Read more
EffectS of black barberry (berberis integerrima) fruit: a review study (Review)
Introduction Berberis integerrima, commonly known as black barberry, is a tradit...Read more
Effects of HTLV‑1 on leukocyte trafficking and migration in ACs compared to healthy individuals (Research Paper)
Human T-cell lymphotropic virus-1 (HTLV-1) is a retrovirus that can cause variou...Read more
Effects of Recombinant Human Follistatin-like 1 (rhFSTL1) Treatment Combined with Phenytoin on Maximal Electroshock-Induced Seizures in Mice (Research Paper)
The effect of recombinant human follistatin-1 and phenytoin alone and their comb...Read more
Effects of short-term high-dose glucocorticoid administration on selected histological and functional aspects of prostate gland in normal rats (Research Paper)
Glucocorticoids are prescribed for a diverse list of health conditions owing to ...Read more
Effects of zinc oxide nanoparticles on pancreas oxidative stress pathway in diabetic rats (Research Paper)
Zinc oxide nanoparticles show potential antioxidant and glucose lowering effects...Read more
Efficacy of Korean Red Ginseng in children with ADHD: an updated narrative review (Review)
Attention deficit hyperactivity disorder (ADHD) stands out as one of the most pr...Read more
Emerging Developments in Transdermal Drug-in-Adhesive Systems: New Approaches to Material Selection, Formulation Design, and Transport Mechanisms (Review)
This comprehensive review explores recent advancements in transdermal drug deliv...Read more
Emerging Role of Extracellular Vesicles in Cancer Diagnosis and Therapy: Opportunities for Precision Medicine (Review)
The three main subgroups of extracellular vesicles (EVs), based on their origin,...Read more
Emerging Strategies for Targeted Therapy in Monogenic Neurological Disorders (Review)
Monogenic neurological disorders are those that are caused by a mutation in a si...Read more
Emorfazone Attenuates NF-κB Gene Expression in a PTZ-Induced Seizure Model in Male Wistar Rats (Research Paper)
Epilepsy is a chronic neurological disorder characterized by recurrent, unprovok...Read more
Empagliflozin Regulates GDF-9, BMP-15, and miR-320 Expression to Improve Folliculogenesis and Oocyte Maturation in Women with PCOS (Research Paper)
Polycystic ovary syndrome (PCOS) is the leading cause of female infertility, aff...Read more
Engineering Alzheimer’s Disease Models and Therapies Using CRISPR-Cas9 Technology (Review)
Introduction: In the earlier years, the majority of AD animal models stemmed fro...Read more
Engineering Probiotics: A Promising Strategy for Modulating Colorectal Cancer Through Balancing the Microbiome (Review)
Colorectal cancer (CRC) is third in incidence and second in cancer-related death...Read more
Enhanced Efficacy of Ceftazidime Against Escherichia coli Through Synergism with Thymol (Research Paper)
This study looked into the antibacterial synergism of thymol/ceftazidime on Esch...Read more
Enhancing Chemotherapeutic Efficacy: The Cytotoxic and Apoptosis-Inducing Properties of Pyrano-Chromene Derivatives in MCF-7 Breast Cancer Cells (Research Paper)
Breast cancer is one of the most common causes of cancer-related deaths and ofte...Read more
Enhancing Daunorubicin Chemosensitivity in T-Cell Acute Lymphoblastic Leukemia Through p53R2 Gene Silencing via siRNA (Research Paper)
T-cell acute lymphoblastic leukemia (T-ALL) is an extensive malignant neoplasm m...Read more
Enhancing Quality of Life in Autistic Adults: A Review of the Interventions (Review)
Autism spectrum disorder individuals always have different issues, such as sleep...Read more
Enhancing sperm quality during cryopreservation in asthenozoospermic men: Melatonin as a regulator of apoptosis and membrane integrity (Research Paper)
Sperm cryopreservation is a vital procedure in assisted reproductive technologie...Read more
Epigenetic Adaptations of Extremophilic Bacteria: Insights into Survival under Cosmic Stress (Review)
The study of extremophilic bacteria has unveiled remarkable strategies that enab...Read more
Epigenetic Alterations in Hereditary Neurological Disorders (Review)
The genetic mutations that cause hereditary neurological disorders (HNDs) includ...Read more
Epigenetic biomarkers in aging and longevity: Current and future application (Review)
Aging is shaped by genetic, epigenetic, molecular, and environmental factors. Am...Read more
Epigenetic Effects of Maternal Nicotine Exposure on the HPA Axis and Stress Response in the Next Generation (Review)
Maternal exposure to nicotine, commonly through smoking or vaping, has been link...Read more
Epigenetic Reprogramming with RNA Molecules: A New Frontier in Combating Drug-Resistant Gastric Cancer (Review)
Gastric cancer (GC) is the fourth most common cause of death globally, and drug ...Read more
Epigenetic-Neurotransmitter Interactions in Response to Nicotine and Morphine (Review)
Nicotine and morphine are two well-known substances that influence pain regulati...Read more
Epithelial-Mesenchymal Transition and Angiogenesis in Prostate Cancer (Research Paper)
Angiogenesis and epithelial–mesenchymal transition (EMT) are major drivers of ...Read more
Epitranscriptomic Modifications and Anoikis Resistance in Virus-associated Cancers (Review)
Anoikis is a process of cell death, and anoikis resistance is one of the feature...Read more
Evaluating Cytotoxic Effects of Doxorubicin on MDA-MB-231 Triple-Negative Breast Cancer Cells (Research Paper)
Breast cancer is one of the most prevalent malignancies among women and remains ...Read more
Evaluating the Prolonged Influence of Mobile Health Programs on Glycemic Management and Lifestyle Adjustments Among Older Adults with Type 2 Diabetes (Research Paper)
This study aims to evaluate the long-term effects of mobile health education on ...Read more
Evaluation and Comparison of the Antioxidant Properties of Carvacrol and Satureja Khuzestanica Essential Oil in Free and Nanoliposome Forms (Research Paper)
Today, diabetes is one of the leading causes of death worldwide, and it is predi...Read more
Evaluation of Biological Effects of RGD Peptide Labeled with Indium-113 m Radionuclide on Cancer Cells Expressing αvβ3 Integrin (Research Paper)
The phenomenon of angiogenesis, as a key factor in the growth and spread of canc...Read more
Evaluation of Common Breast Cancer Polymorphisms in Iranian Ethnic Groups by Gender and Investigation of Drug Side Effects (Research Paper)
Breast cancer is a leading cause of cancer-related morbidity and mortality world...Read more
Evaluation of common Breast cancer polymorphisms in women under 40 years and assessment of targeted therapy pathways with lower drug side effects (Research Paper)
Breast cancer susceptibility is influenced by multiple genetic variants, notably...Read more
Evaluation of common polymorphisms in CLL cancer in the Iranian genome profile by gender in patients and drug selection based on targeted therapy. (Research Paper)
Introduction :Chronic Lymphocytic Leukemia (CLL) is a type of cancer that start...Read more
Evaluation of common polymorphisms in Thalassemia patients (Research Paper)
Thalassemia is a genetic blood disorder caused by mutations in hemoglobin genes,...Read more
Evaluation of Common Polymorphisms in the BRCA1 Gene in the Iranian Genomic Profile of Breast Cancer by Age and Assessment of Drug Side Effects (Research Paper)
Breast cancer is the most common malignancy among Iranian women, with incidence ...Read more
Evaluation of Grape Seed Extract Against CGRP in Migraine Using Molecular Docking (Research Paper)
Migraine, one of the most prevalent disabling neurological disorders, is charact...Read more
Evaluation of Hexokinase Enzyme Function in Breast Cancer (Research Paper)
Breast cancer is the most commonly diagnosed cancer and second leading cause of ...Read more
Evaluation of molecular Macrolide Resistance mechanisms in strains of Viridans Group Streptococci isolated from Urinary Tract Infections (UTI) (Research Paper)
Urinary tract infections (UTIs) encompass bladder infections (cystitis), kidney ...Read more
Evaluation of Novel Approaches in Prevention, Diagnosis, and Treatment of Brucellosis in Humans and Animals: A Review (Review)
Brucellosis is one of the most important infectious diseases worldwide, affectin...Read more
Evaluation of OSTEONECTIN Protein Expression in Mesenchymal Stem Cell Encapsulated into Chitosan/Carboxymethyl chitosan Hydrogel Treated with Exosome (Research Paper)
Extracellular nanovesicles secreted by mesenchymal stem cells have been introduc...Read more
Evaluation of Phenotype-Associated Polymorphisms in Breast Cancer and Colon Cancer Profiles in the Iranian Population, Along with an Assessment of Chemotherapy Drug Adverse Effects (Research Paper)
The aim of this study was to identify key single-nucleotide polymorphisms involv...Read more
Evaluation of Polyurethane nanofibers treated with Cold Atmospheric Plasma for tissue engineering (Research Paper)
Polyurethane (PU) is polymer valued for their excellent mechanical properties, i...Read more
Evaluation of the anti apoptotic effect of carotenoids isolated from the BM1 bacterial strain from mangrove forests in Iran on prostate cancer cell line (DU145) (Research Paper)
Mangrove ecosystems, characterized by extreme conditions such as high salinity, ...Read more
Evaluation of the Antimicrobial Effects of Ethanolic and Acetonic Extracts of Orange and Quince Peels on Burn Infections Caused by pseudomonas aeruginosa in Mice (Research Paper)
Pseudomonas aeruginosa is a major cause of hospital-acquired and drug-resistant ...Read more
Evaluation of the effect of synbiotic and probiotic products on iron storage disease in Mynah birds: clinical and imaging findings (Research Paper)
Iron storage disease which majorly resembles idiopathic (hereditary) hemochromat...Read more
Evidence Based Nursing Strategies for the Prevention and Management of Delirium in Intensive Care Unit Patients (Review)
Delirium is a frequent and severe complication among intensive care unit (ICU) p...Read more
Examining the gene expression profile of colorectal cancer and functional prediction of some Long Non-Coding RNAs (Research Paper)
In 2020, with an estimated 1.93 million new cases (10%) and 0.94 million deaths ...Read more
Examining the Role of Inulin in Colorectal Cancer: Mechanisms and Therapeutic Potential (Review)
Colorectal cancer (CRC) remains one of the leading causes of illness and cancer-...Read more
Exosomal Non-Coding RNAs as Key Regulators of PD-L1-Mediated Immune Escape in Colorectal Cancer (Review)
Still, colorectal cancer (CRC) is considered to be the leading cause of cancer-r...Read more
Exosome-Based Strategies for Skin and Hair: Insights from Wharton’s Jelly MSCs (Review)
Exosomes, as nanosized extracellular vesicles, are emerging as innovative tools ...Read more
Exosomes as Cell-Free Therapeutic Agents for Diabetic Wound Healing: Mechanisms, Delivery Strategies, and Clinical Prospects (Review)
Diabetic wounds represent a significant clinical challenge due to their chronic,...Read more
Exosomes as Innovative Biomarkers in the Diagnosis and Treatment of Female Infertility (Review)
Infertility has become a major issue, especially in aging societies. While tradi...Read more
Exosomes as tools for personalized miRNA delivery in infertility treatment (Review)
Infertility is an important health issue for about 15% of couples around the wor...Read more
Exosomes derived from Stem Cells enhance Etoposide-induced apoptosis in HepG2 Cells (Research Paper)
Hepatocellular carcinoma (HCC) represents the most common type of liver malignan...Read more
Exosomes in Regenerative Medicine: A Cell-Free Therapeutic approach (Review)
Regenerative medicine is an emerging field aimed at repairing, replacing, or reg...Read more
Exosomes of Mesenchymal Stem Cells stimulated by Lipopolysaccharide can alleviate and treat Nonalcoholic Fatty Liver Disease in High Fat Diet-Fed Rats. Introducing a new remedy (Research Paper)
Nonalcoholic fatty liver disease, called NAFLD, is a liver disease in which too ...Read more
Expanding Horizons of piRNAs: Roles in Cancer Biology and Therapeutic Potential (Review)
PIWI-interacting RNAs (piRNAs) are a unique class of small non-coding RNAs, typi...Read more
Exploring the Challenges of Palliative Care in the Elderly: A Review Study (Review)
Introduction: The global rise in the elderly population has significantly increa...Read more
Exploring the luteolin as EGFR inhibitor on gastric cancer based on molecular docking (Research Paper)
Gastric cancer has become the fourth most common type of cancer and is the secon...Read more
Exploring the Synergistic Potential of Thymol and Ceftazidime Against Acinetobacter baumannii Enhancing Antibiotic Efficacy (Research Paper)
This study aimed at the antimicrobial effects of thymol/ceftazidime on Acinetoba...Read more
Extracellular Vesicle Derived MicroRNAs as Non-Invasive Biomarkers for Distinguishing Benign from Malignant Breast Lesions Categorized as Breast Imaging Reporting and Data System Category Four (Review)
Early detection of breast cancer is crucial for improving patient outcomes. Conv...Read more
Fabrication and characterization of mucoadhesive tragacanth gum/silk fibroin nanoparticles by anti-solvent precipitation method for use in oral drug delivery (Research Paper)
Tragacanth gum, is widely used in the development of drug delivery systems due t...Read more
Fabrication of Bio -adhesive gel for Tissue Regeneration : In Vitro and In Vivo study (Research Paper)
Using natural compounds can overcome the disruption of traditional sutures and t...Read more
FDA-Approved HDAC Inhibitors as Epigenetic Modulators: Identifying Optimal Candidates for Enhancing Pluripotency Induction (Research Paper)
Histone deacetylases (HDACs) are a key group of enzymes that regulate chromatin ...Read more
Ferroptosis as a therapeutic strategy in cancer (Review)
Cancer remains one of the most serious threats to human health. Although a varie...Read more
Fetal Circulating Tumor DNA in Maternal Blood: Expanding Noninvasive Prenatal Testing to Early Cancer Detection (Review)
Cell-free DNA (cfDNA) refers to fragments of nucleic acids circulating freely in...Read more
Fetal Presence in the Bladder Detected on Ultrasound: A Case Report (Research Paper)
Vesicouterine fistula is a rare kind of fistula with significant complications. ...Read more
Frequency of Virulence Factors and stx1 and stx2 Genes in Fecal and Raw Food Isolates of Shigatoxigenic Escherichia coli (Research Paper)
Shiga toxin-producing bacteria are an important pathogen in foodborne diseases, ...Read more
From Donor Tissue to iPSC-Derived Cells: Future Perspectives of RPE Transplantation in Visual Disorders (Review)
The retinal pigment epithelium (RPE) plays a critical role in retinal health, su...Read more
From Genes to Metabolism: The Role of SNPs and Hexokinase in Prostate Cancer Development (Research Paper)
Prostate cancer is a leading malignancy among men worldwide, with both environme...Read more
From Metabolic Risk to Reproductive Health: Digital Twin Simulations for Optimizing Therapy in Diabetes and PCOS (Review)
Diabetes mellitus and polycystic ovary syndrome (PCOS) are among the most preval...Read more
From Nucleotide to Clinic: Computational Paths for Early Detection of Pancreatic Ductal Adenocarcinoma via Liquid Biopsy (Review)
Pancreatic Ductal Adenocarcinoma (PDAC) has devastating consequences and is usua...Read more
Fumaria parviflora causes the improvement of blood oxidative factors and tissue parameters of the testis in streptozotocin-induced type 1 diabetic rats (Research Paper)
According to an estimation in 2010, there are 48.5 million infertile couples in ...Read more
Fungal Biosorption: A Sustainable and Non-Metal-Producing Strategy for Heavy Metal Removal from Wate (Review)
As industrial activities continue to increase, the introduction of heavy metals ...Read more
Fungal microbiome in colorectal cancer: a systematic review (Review)
Colorectal cancer (CRC) is recognized as one of the leading causes of cancer-rel...Read more
Fusobacterium nucleatum and Colorectal Cancer: Therapeutic Potential of Gold Nanoparticles (AuNPs) (Review)
Fusobacterium nucleatum, a Gram-negative anaerobic bacterium, has recently been ...Read more
Gamifying Medical Education through AI: Evidence, Engagement Patterns, and Pedagogical Implications (Review)
Gamification, the strategic incorporation of game‐design elements into educati...Read more
Gangrene and Its Treatment: A Comprehensive Review of Modern Diagnostic and Therapeutic Approaches (Review)
Gangrene is a severe and potentially fatal condition characterized by the loss o...Read more
Gene Therapy-Driven CAR-T Cell Therapy: A New Horizon for Immune System Activation in Cancer Treatment (Review)
Chimeric Antigen Receptor T-cell (CAR-T) therapy has emerged as a groundbreaking...Read more
Gene-Driven Amygdala Remodeling in ASD via Orgo-Seq and Neuronal Transdifferentiation (Review)
Autism spectrum disorder (ASD) is linked to amygdala hypertrophy and synaptic dy...Read more
Genetic and Epigenetic Biomarkers in the Diagnosis and Treatment of Endometriosis: A Mini-Review (Review)
Endometriosis is a chronic, estrogen-dependent inflammatory disorder affecting a...Read more
Genetic engineering of human follicular stem cells using bacterial plasmids containing Wnt10b and β-catenin genes for hair follicle regeneration in the treatment of androgenetic alopecia (Review)
Androgenetic alopecia is the most common type of progressive hair loss caused by...Read more
Genetic Evaluation of Pancreatic Cancer Development in Individuals with a Congenital Obesity Phenotype in Iran (Research Paper)
Pancreatic cancer is one of the most lethal and challenging types of gastrointes...Read more
Genetic Insights into Bacterial Resistance and Nano-Strategies to Overcome It (Review)
Antibiotic resistance is now a serious problem for world health. Antibiotics are...Read more
Genetic Insights into MLH1 rs1800734 and Colorectal Cancer: Evidence from the Largest Iranian Cohort with Meta-Analysis (Research Paper)
Colorectal cancer (CRC) is the third most common cancer worldwide and the second...Read more
Genetic Polymorphisms and Pharmacogenetics in Lung Cancer: Implications for Disease Susceptibility and Adverse Drug Reactions (Research Paper)
Lung cancer is a major global health challenge influenced by various genetic fac...Read more
Genetic predictors of adverse events with cutaneous melanoma systemic therapy (Research Paper)
Cutaneous melanoma is a malignant tumor of melanocytes and represents the most a...Read more
Genetic Risk Scores and Personalized Interventions in Preventing Cardiovascular Disease: A Narrative Review (Review)
Cardiovascular disease (CVD) remains the leading cause of mortality worldwide. W...Read more
Genome Editing Using CRISPR-Cas9: Opportunities, Challenges, and Future Perspectives (Review)
Recent progress in biotechnology has provided scientists with tools that were on...Read more
Genomics-Guided Identification of ALK and TrkB as Therapeutic Targets in Neuroblastoma (Research Paper)
Neuroblastoma, one of the most common neuroectodermal tumors in childhood, is ch...Read more
Gestational weight gain is related with socioeconomic status, anxiety score, pre-pregnancy BMI, and parity among Postpartum Women Attending Comprehensive Health Centers Affiliated with Iran University of Medical Sciences, 2021–2023. (Research Paper)
Appropriate gestational weight gain directly affects the health of both mother a...Read more
Green Synthesis of Nanoparticles by Laser Ablation (Review)
Laser Ablation in Liquids (LAL) is a rapidly advancing, single-step technique fo...Read more
Green-Synthesized Selenium Nanoparticles Using Flavonoids: A Promising Therapeutic Strategy against Cancer (Review)
The green synthesis of selenium nanoparticles (SeNPs) using flavonoids has gaine...Read more
Gut Microbiome and Neuroepigenetics: Investigating the Role of Gut Microorganisms in Regulating Brain Genes and Their Impact on Mental Health (Research Paper)
The gut_brain axis is a bidirectional communication pathway between the gastroin...Read more
Gut Microbiota and Immune Response to Vaccines (Review)
Several animal and human studies have highlighted the crucial role of the gut mi...Read more
Gut microbiota in cancer immune response and immunotherapy — Abstract review (Review)
The gut microbiota is a systemic regulator of host immunity and a modifiable ext...Read more
Gut–Brain Axis and Premenstrual Syndrome: The Role of Microbiota and Nutrition in Psychological Symptom Regulation (Review)
Premenstrual Syndrome (PMS) is a highly prevalent condition, affecting up to 80%...Read more
Haplotype association analysis of ALMS1 gene variants across patients with obesity and diabetes (Research Paper)
The ALMS1 gene encodes a large protein primarily localized at the base of primar...Read more
Harnessing Artificial Intelligence for the Discovery and Development of Herbal Therapies in Treating Depression and Anxiety (Review)
Depression and anxiety are among the most widespread psychiatric disorders globa...Read more
Harnessing Artificial Intelligence to Identify Natural Lipid-Lowering Agents Targeting Lipin-1 (Research Paper)
Lipin-1, a critical protein involved in triglyceride synthesis and fatty acid ox...Read more
Harnessing Stem Cell-Derived Exosomes as Advanced Delivery Systems for microRNA-Based Therapy in Diabetic Wound Healing (Review)
Diabetic wound healing is a multifaceted process often disrupted by persistent i...Read more
Harnessing the fundamental roles of vitamins: the potent anti‑oxidants in longevity (Review)
Introduction: Aging is a complex biological process characterized by a progressi...Read more
healthcare Provider Burnout and Patient Safety: A Narrative Review (Review)
Burnout is prevalent among healthcare professionals, including medical students,...Read more
Hepatitis B Virus (HBV) Replication in HepG2 Cell Line (Research Paper)
Hepatitis B virus (HBV) is a leading cause of liver diseases, including chronic ...Read more
Hepatitis E Virus: Evolution, Clinical Impact, and Advances in Diagnosis, Treatment, and Prevention (Review)
Hepatitis E virus (HEV) produces acute viral hepatitis, which creates a worldwid...Read more
Hexokinase Enzymes in Lung Cancer: Mechanisms and Therapeutic Implications (Research Paper)
Lung cancer is among the leading causes of cancer-related mortality worldwide, I...Read more
High-intensity interval training (HIIT) and methylphenidate (alone and in combination) alleviates tramadol-induced cardiac side effects in male rats, potentially through the modulation of mitochondrial function (Research Paper)
Tramadol, a commonly prescribed analgesic for moderate to severe pain, has been ...Read more
How Biomimetic Tissue Engineering Scaffolds Are Reshaping Regenerative Medicine (Review)
Tissue engineering scaffolds serve as the foundation for addressing this critica...Read more
How do key minerals influence cancer risk and progression? (Review)
Various bioactive compounds found in food, such as vitamins and minerals, have b...Read more
Hsv Infection from epidemology to next-generation therapies (Review)
Introduction: The diagnosis of virus genital herpes is typically challenging be...Read more
Human Olfactory Ectomesenchymal Stem Cells (OE-MSCs) Display Schwann Cell-Like Phenotypes and Promote Neurite Outgrowth In vitro (Research Paper)
Strategies of Schwann cell (SC) transplantation for regeneration of peripheral n...Read more
Hypermethylation of HOXA4 Gene Promoter and Its Potential Association with Disease Progression, Imatinib Resistance, High Sokal Score Risk, and Smoking among Chronic Myeloid Leukemia Patients (Research Paper)
The evolution of resistance to imatinib and disease progression are multifactori...Read more
Hypoandrogenism in the elderly with metabolic syndrome: prevalence, complications, and treatment (Review)
Hypoandrogenism, common yet often underdiagnosed in elderly men, is characterize...Read more
Identification and Bioinformatic Analysis of Hexokinase Related Genes in Colorectal Cancer (Research Paper)
Colorectal cancer (CRC) is the third most common cancer worldwide, following lun...Read more
Identification of a Novel Variant in the PODXL Gene in a Turkish Family With Focal Segmental Glomerulosclerosis (Research Paper)
Focal Segmental Glomerulosclerosis (FSGS) is a clinicopathological disorder char...Read more
Identification of AKT1 as a Key Hub Gene in Cisplatin-Resistant Ovarian Cancer Using Bioinformatics Analysis (Research Paper)
Ovarian cancer is the third most common gynecologic malignancy. The chemoresista...Read more
Identification of common epitope for GAD65 in three different servers (Research Paper)
Introduction: The incidence of diabetes mellitus (DM) has experienced a fourfol...Read more
Identification of DNA methylation biomarkers for early detection and prognosis of colorectal cancer using genome-wide DNA methylation profiles (Research Paper)
Colorectal cancer is a common malignancy and a leading cause of cancer-related m...Read more
Identification of genes associated with metastasis in hepatocellular carcinoma through microarray data analysis (Research Paper)
Liver cancer is the fifth most common cancer and the fourth leading cause of can...Read more
Identification of key genes in Amyotrophic lateral sclerosis through systems biology (Research Paper)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterize...Read more
Identification of Microbes, Infectious Diseases, and Their Prevention Methods (Review)
Microbes, known as microscopic organisms, are actively present at all levels of ...Read more
Identification of Mucosal HPV in Wastewater from Tehran Hospitals (Research Paper)
Human papillomaviruses (HPVs) are a large and heterogeneous group of DNA viruses...Read more
Identification of Potential Prognostic Biomarkers in Grade II Astrocytoma: A Systems Biology Approach (Research Paper)
Grade II astrocytoma is a subtype of diffuse and infiltrative glioma that has ...Read more
Identification of regulatory networks and key pathways mediated by lncRNAs in non-small cell lung cancer (NSCLC) using bioinformatics analyses (Research Paper)
Non-small cell lung cancer (NSCLC), as the most common type of lung cancer, is a...Read more
Identification of SNPs in Data Related to Folic Acid Metabolism (MTHFR and DHFR Genes) and Their Association with Breast Cancer Risk in the Iranian Population and Other Countries (Research Paper)
Breast cancer is the second most common malignancy worldwide after lung cancer, ...Read more
Identification of unique ZnT8 epitopes for antidiabetic vaccine design in three different servers (Research Paper)
Introduction: Type 1 diabetes is delineated by the obliteration of pancreatic ...Read more
Identifying Functional SNPs in Vitamin D Receptor Genes and Their Impact in Ovarian Cancer (Research Paper)
Introduction: Ovarian cancer as the eighth most common cancer of women globally,...Read more
IgY Antibodies: A Novel Strategy Against Antibiotic-Resistant Bacterial Infections (Review)
Antibiotic-resistant bacteria are an emerging threat to global health security. ...Read more
Immobilization of Candida rugosa lipase for resolution of racimic ibuprofen (Research Paper)
Aim Due to lipases’ regio-selectivity and ability to catalyze different reacti...Read more
Immunological and Potentially Therapeutic Aspects of Galectins in Graft-versus-Host Disease (Review)
Graft-versus-host disease (GVHD) remains a major challenge in allogeneic hematop...Read more
Immunotherapy in acute myeloid leukemia: An emerging and promising strategy for leukemia treatment (Review)
Acute myeloid leukemia (AML) is a blood cancer originating from the malignant my...Read more
Impact of Escherichia coli Nissle 1917 on Colorectal Cancer: A Review (Review)
Colorectal cancer (CRC) is one of the most prominent public health challenges, a...Read more
Impact of Microplastics in Ovarian Follicular Fluid on Oocyte Quality and Early Embryo Development: A Systematic Review and Meta-analysis (Review)
Microplastics are emerging environmental contaminants with endocrine-disrupting ...Read more
Impact of Midwifery-Led Care on Maternal Mental Health: A Systematic Review (Review)
Maternal mental health is a fundamental component of reproductive health, direct...Read more
Impact of miR146 rs6864584 polymorphism on risk of polycystic ovarian syndrome in the Southeast Iranian population (Research Paper)
Polycystic ovary syndrome (PCOS) is a multifactorial endocrine disorder that occ...Read more
Impact of the Ketogenic Diet on Seizure Control and Cognitive Function in Children with Neurometabolic Disorders (Review)
Neurometabolic disorders in children, such as glucose transporter type 1 deficie...Read more
Implications of Peptidyl Arginine Deiminase 4 gene transcription and polymorphisms in susceptibility to rheumatoid arthritis in an Iranian population (Research Paper)
Peptidyl arginine deiminase 4 (PADI4) has been implicated in Rheumatoid arthriti...Read more
Improved Metastatic Risk-Stratification in Cutaneous Squamous Cell Carcinoma with the 40-Gene Expression Profile Test (Review)
The second most common form of skin cancer is Cutaneous squamous cell carcinoma ...Read more
Improving Medication Compliance and Self-Management in Elderly Type 2 Diabetes Patients through Mobile Health Education (Research Paper)
Diabetes is the most common endocrine disease worldwide. Its prevalence increase...Read more
In Silico Evaluation of Apilimod Targeting MMP-9 in Pancreatic Cancer (Research Paper)
Matrix metalloproteinase-9 (MMP-9) is involved in extracellular matrix remodelin...Read more
In silico Molecular Docking Analysis of Paclitaxel with the Anti-Apoptotic Protein Bcl2 (Research Paper)
Molecular docking provides a comprehensive framework for understanding drug–pr...Read more
In Silico Optimization of gRNA Design for CCND1 Gene Silencing in Breast Cancer Stem Cells Using CRISPRoff and Structural Bioinformatics (Research Paper)
Cyclin D1 (CCND1) is the major contributor to malfunction of the cell cycle and ...Read more
In Silico Optimization of Ipilimumab: Site-Directed Mutagenesis to Enhance CTLA-4 Binding Affinity (Research Paper)
The regulation of T-cell activity is critically dependent on immune checkpoints,...Read more
In Situ Self-Crosslinkable and Long-Term Stable Hyaluronic Acid Hydrogel Dermal Filler with Vitamin E Release on Fibroblast Cells for Tissue Augmentation and Skin Wrinkle Correction (Research Paper)
Dermal fillers, particularly hyaluronic acid (HA)-based ones, are widely used in...Read more
In Vitro Synergy Between Thymol and Ampicillin Against Escherichia coli Clinical Strains (Research Paper)
This study aimed to investigate the synergistic effect of thymol/ampicillin on E...Read more
Indomethacin-Associated Transient Hyperglycemia in a Well-Controlled Type2 Diabetic Patient : A Case Report (Research Paper)
Indomethacin is a widely used nonsteroidal anti-inflammatory drug (NSAID) for mu...Read more
Inflammation and Infertility: Immunopathological Mechanisms, Diagnostic Challenges, and Emerging Therapies (Review)
Almost 15 percent of women of reproductive age experience infertility around the...Read more
Inhibition of Human HepG2 Hepatocellular Carcinoma Cell Line Growth by Metabolites from a Clinical Strain of Pseudomonas aeruginosa D121 In Vitro (Research Paper)
Cancer, as the second leading cause of human mortality, imposes substantial soci...Read more
inhibitory effects of different phytochemicals on EGFR (Research Paper)
Receptor Tyrosine Kinases (RTKs) are a family of membrane-bound receptors that a...Read more
inhibitory effects of different phytochemicals on VEGFR-2 (Research Paper)
Vascular endothelial growth factor receptor-2 (VEGFR-2), a receptor tyrosine kin...Read more
Inhibitory Effects of Zataria multiflora Essential Oil Nanophytosomes on Listeria monocytogenes in Lamb Meat: A Comparative Analysis of Response Surface Method and Neural Fuzzy Inference System in Antibacterial Activity and Virulence Gene Expression (Research Paper)
The infectious potential of Listeria monocytogenes is susceptible to alteration ...Read more
Injectable Nanocosmetics: Design of Smart Nanoparticle-Based Fillers for Skin Rejuvenation, Anti-Aging, and Regeneration with a Precision and Translational Medicine Approach (Review)
In recent decades, the field of aesthetic medicine has witnessed remarkable adva...Read more
Innovative Biotechnological Approaches in Pancreatic Cancer Therapy (Review)
Abstract: Pancreatic cancer is one of the deadliest types of cancer. Treatment ...Read more
Innovative research in the development of leishmaniasis prevention through leishmaniasis vaccine: modulation of GAPDH-mediated immune response (Research Paper)
Leishmaniasis represents one of the most neglected tropical diseases, causing se...Read more
Insight to Gonorrhea is on the verge of becoming incurable: A review of the antimicrobial mechanisms of Neisseria gonorrhoeae and the therapeutic challenges ahead (Review)
Gonorrhea is a condition that has infected humans since ancient times. The disea...Read more
Insight to Human papilloma virus diagnosis and vaccination (Review)
The HPV vaccination is now included in the national program of over 140 countrie...Read more
Insight to Streptococcus pneumoniae and Its Relationship with the Antibiotic Streptomycin (Review)
Streptococcus pneumoniae is a Gram-positive, facultative aerobic, lanceolate-sha...Read more
Insight to the gut-brain connection , new Ideas for Treating Brain Diseases (Review)
The connection between the gut and brain plays a crucial role in both health and...Read more
Insight to the role of probiotics in Controlling Antibiotic – Resistant in the Human Gastrointestinal Tract with Emphasis on Escherichia coli and Enterococcus sp. (Review)
Introduction: The global rise of antibiotic resistance has emerged as a major p...Read more
Integrated LAMP-Microfluidic System for Diagnosis of Moraxella catarrhalis (Research Paper)
Timely and accurate identification of respiratory pathogens is essential for eff...Read more
Integrated TCGA and GSE132956 Analysis Utilizing the R-STRING-Cytoscape-GEPHI Pipeline: Identification of Cut-point Proteins and Biomarkers for the Early Detection of Pancreatic Ductal Adenocarcinoma (Research Paper)
Pancreatic ductal adenocarcinoma (PDAC) continues to be a fatal tumor, with 5-ye...Read more
Integrating Artificial Intelligence and CRISPR-Cas9 for Optimized gRNA Design and Mutation Detection in SLFN11 and KEAP1 Genes of Lung Cancer (Research Paper)
Lung cancer is one of the most lethal malignancies worldwide, largely due to its...Read more
Integrating Cell-Free DNA and Microbiome Signatures for Early Detection of Colorectal Cancer (Review)
Colorectal cancer (CRC) is one of the leading causes of cancer-related death wor...Read more
Integrating Machine Learning with Magnetic Nanoparticle–Based Hyperthermia for Precision Cancer Therapy: A Targeted Review of Recent Evidence (Review)
Magnetic nanoparticle (MNP)–mediated hyperthermia has been recognized since th...Read more
Integrating Monoclonal Antibody Therapy with Complementary Medicine: A Bioinformatic and Chemoinformatic Deep Dive into Gene and Compound Networks in Alzheimer’s Disease (Research Paper)
Alzheimer’s disease is a progressive neurodegenerative disorder and the primar...Read more
Integrating PET Imaging in Personalized Medicine for Enhanced Cancer Diagnosis: Targeting Molecular Pathways in Precision Oncology (Review)
Positron emission tomography (PET) has emerged as a cornerstone of precision onc...Read more
Integrating Transcriptomic Data into Flux Balance Analysis: Algorithms, Challenges, and Biomedical Applications (Review)
Integrating transcriptomic data into genome-scale metabolic models enhances the ...Read more
Integration of artificial intelligence with genetic and epigenetic data to predict implantation success and reduce the likelihood of miscarriage in the IVF process (Review)
In vitro fertilization (IVF) has transformed reproductive medicine, yet its succ...Read more
Integrative Analysis of MPO Variants, Gene Expression, and Epigenetic Regulation in Host Susceptibility to Biological Agents: Molecular Performance Assessment, Environmental/Biological Monitoring, and Immune‑Response Modeling for Non‑Kinetic Defense Strategies” If you prefer a shorter version for running title or submission: “MPO Variants, Expression, Epigenetics and Immune Modeling for Non‑Kinetic Defense” (Review)
Myeloperoxidase (MPO) is a heme-containing peroxidase predominantly expressed in...Read more
Integrative Immunometabolic Profiling for Predicting Immune Checkpoint Inhibitor Response in Hepatocellular Carcinoma: A Retrospective–Prospective Multi-Omics Study (Review)
Immune checkpoint inhibitors (ICIs) have transformed the therapeutic landscape o...Read more
Integrative Multi-Omics and Mechanistic Modeling Uncover HK2-Driven Warburg Vulnerabilities in Pancreatic Cancer (Research Paper)
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy characteri...Read more
Intelligence in Every Drop: How Machine Learning-Driven Liquid Biopsy is Shaping the Future of Multi-Cancer Early Detection (Review)
According to a report by the World Health Organization, in the year 2020, one in...Read more
Interactive Networking of SNPs in Zinc Absorption Pathways (ZIP/Znt) and Prostate Cancer Prognosis: A Systems Biology Approach (Research Paper)
Prostate cancer (PCa) is the second most common cancer in men globally, and ther...Read more
Interleukin-10 Promoter 1082G/A Polymorphism in and Relation to Gastric Cancer by Tetra Arms PCR (Research Paper)
Gastric cancer is the second common cause of cancer death worldwide. Cytokines a...Read more
Interplay between dysregulated micrornas and pharmacological outcomes in prostate cancer: a molecular docking and bioinformatics approach (Research Paper)
Background: Prostate cancer (Pca) is among the most prevalent malignancies in me...Read more
Interplay Between Host Genetics and Microbiome in Health and Disease (Review)
The human microbiome represents a dynamic and intricate ecosystem of microorgani...Read more
Interplay between Viruses & Human microRNAs: Implications for Cancer Pathogenesis (Review)
Recent studies have demonstrated that certain viruses are capable of disrupting ...Read more
Interpreting Antimicrobial Resistance in Veterinary Pathogens: Lessons from Systems Biology and Single-Cell Analysis (Review)
Antimicrobial Resistance (AMR) in veterinary pathogens represents threats to ani...Read more
Introduction of peptides affecting insect sodium channels from the transcriptome of the venom gland of the scorpion Odontobuthus doriae for the production of biocompatible insecticides (Research Paper)
Traditional chemical insecticides, in addition to their side effects on non-targ...Read more
Introduction of some antimicrobial peptides derived from transcriptome analysis of the venom gland of the scorpion Odontobuthus doriae as candidates for use in the food industry (Research Paper)
In recent decades, increasing demand for healthy foods and concerns regarding ch...Read more
Investigating Hepatitis E Virus genome in Tehran’s Hospital Wastewater (Research Paper)
Hepatitis E is a member of Hepeviridae family and is one of the leading causes o...Read more
Investigating mass spectrometry methods in identifying neoantigens and its application in designing personalized cancer vaccines (Review)
Immunotherapy, especially personalized vaccines based on neoantigens, has become...Read more
Investigating the Association Between Acrylamide Exposure and Cancer Risk: A Targeted Review and Translational Perspective (Review)
Acrylamide (AA) is a small, water-soluble industrial monomer that can also form ...Read more
Investigating the association between HLA-B27 and Ankylosing spondylitis in Fasa city (Research Paper)
Ankylosing spondylitis is a chronic inflammatory disease that affects the spine,...Read more
Investigating the Development of Unconventional T Cells in the Human Thymus (Review)
The human thymus plays a central role in the development of T cells, which are c...Read more
Investigating the effect of aromatherapy on reducing nausea and vomiting in cancer patients undergoing chemotherapy (Review)
Chemotherapy, a vital cancer treatment, is often accompanied by serious side eff...Read more
Investigating the effect of simultaneous administration of 5-fluorouracil and spirulina on the expression of inflammatory factors in mouse and human breast cancer cell lines (Research Paper)
Breast cancer remains a major global health challenge for women, with issues suc...Read more
Investigating the Effects of Inulin on Thyroid Cancer: Mechanisms and Treatment Potential (Review)
Thyroid cancer is the most prevalent malignant neoplasm of the endocrine glands,...Read more
Investigating the effects of silver nanoparticles synthesized with Echinophora platyloba on breast cancer cells by MTT assay (Research Paper)
Breast cancer treatment is fraught with significant challenges. Echinophora plat...Read more
Investigating the Effects of Synthetic Silver Nanoparticles with Echinophora platyloba on Breast Cancer Cells by Scratch Assay (Research Paper)
Breast cancer is a significant disease with treatment challenges. Echinophora p...Read more
Investigating the efficiency of neural differentiation of human mesenchymal stem cells on composite polymer films copolymerized (Research Paper)
Introduction Peripheral nerve injuries often result in significant loss of sens...Read more
Investigating the impact of Alpha Binaural waves on sleep quality and daily performance of teachers aged 40 to 50 in the metropolis of Rasht (Research Paper)
Sleep is one of the most important need of humans. Approximately one-third of ea...Read more
Investigating the interaction between the PTTG1 gene as a potential biomarker and its associated miRNA in prostate cancer through bioinformatics analysis (Research Paper)
Prostate cancer (PCa) is the second most frequently diagnosed cancer in men and ...Read more
Investigating the potential of inhibiting Klebsiella pneumoniae beta-lactamase using the compounds identified by the GC-Mass method in the essential oil of Mentha pulegium based on the crystal structure of OXA-48 through molecular docking methods and investigating the toxicity and medicinal properties of the compounds. identified with the highest affinity to the OXA-48 protein structure (Research Paper)
The rise of antibiotic-resistant bacteria, particularly Klebsiella pneumoniae, p...Read more
Investigating the relationship between psychological stress and salivary cortisol levels in students of the third stage of the Iranian Science Olympiads: A pre-test-post-test psychophysiological study (Research Paper)
Scientific Olympiads in Iran are among the most competitive academic pathways fo...Read more
Investigating the Role of Fish-Derived Omega-3 Fatty Acids in Prostate Cancer: A Narrative Review (Review)
Prostate cancer is one of the most common cancers in men, and several factors, i...Read more
Investigating the Role of the Ketogenic Diet in the Prevention and Treatment of Colorectal Cancer: A Narrative Review (Review)
Colorectal cancer (CRC), ranked as the third most common cancer globally with a ...Read more
Investigating the Role of Vitamin D in the Prevention and Treatment of Breast Cancer (Review)
Breast cancer (BC) is one of the most common cancers and a leading cause of deat...Read more
Investigation and analysis of biomarkers in the neurological disease MS using a bipartite miRNA-mRNA network (Research Paper)
MS is an autoimmune disease in which the central nervous system is demyelinated ...Read more
Investigation and comparison of the effectiveness of using two drugs, an antibiotic and an anti-inflammatory, simultaneously in a nanocomposite formulation in improving skin wounds compared to using each drug alone in a laboratory mouse model. (Research Paper)
Chronic wound treatment, especially skin wounds, as an unpleasant complication a...Read more
Investigation into new follicles for the treatment of androgenetic alopecia with stem cells (Review)
Androgenetic alopecia is one of the most common hair-related disorders, especial...Read more
Investigation of Cellular Aging Structures and Processes in the Progression of Endometriosis review article (Review)
Endometriosis is a chronic and often painful condition in which tissue similar t...Read more
Investigation of common polymorphisms in BRCA2 gene and the co-occurrence of breast cancer, along with an evaluation of the adverse effects of chemotherapeutic agents. (Review)
Genetics, particularly BRCA2 and its common SNPs, significantly influence breast...Read more
Investigation of Common Polymorphisms in Melanoma Skin Cancer based on Gender in The Genetic Profile of The Iranian Population and Assessment of Chemotherapy Side Effects (Research Paper)
Melanoma only accounts for about 2% of malignant skin cancer but causes most dea...Read more
Investigation of common polymorphisms in squamous cell skin cancers based on age in Iranian genetic profiles and investigation of side effects of chemical drugs in chemotherapy (Research Paper)
Squamous cell carcinoma of the skin is the second most common non-melanoma skin ...Read more
Investigation of Factors Affecting Gut-Testis Axis Signaling Pathways (Review)
The gut-testis axis represents a bidirectional communication pathway between the...Read more
Investigation of lncRNA HULC Expression in Reovirus-Infected Huh-7 Cells (Research Paper)
Reoviruses are oncolytic viruses that can destroy different cancer cells, such a...Read more
Investigation of the antimicrobial effects of probiotic lactobacilli isolated from whey on on rectovaginal streptococcus agalactiae isolates isolated from pregnant women (Research Paper)
Congenital infections are a significant concern in fetal health. This article di...Read more
Investigation of the Effects of Simvastatin on Lipid Peroxidation and Catalase Activity in the Hippocampus of Bisphenol A-Exposed Rats (Research Paper)
Bisphenol A (BPA) is a widespread environmental toxin capable of crossing the bl...Read more
Investigation of the mechanism of selected natural compounds in breast cancer and endometrial(cancer) through the PI3K/AKT/mTOR signaling pathway by molecular docking (Research Paper)
Despite the advancement of numerous treatments in the field of cancer, cancer re...Read more
Investigation the interaction between NF-κB protein and Astragaloside IV using molecular docking (Research Paper)
The nuclear factor kappa B (NF-κB) signaling pathway is a master regulator of c...Read more
KIR–HLA Combination Predicts Activation-Driven Risk in Chronic Myeloid Leukemia (Research Paper)
Background: Killer-cell immunoglobulin-like receptors (KIRs) regulate natural ki...Read more
KRAS-G12C Inhibition in Cancer Therapy: Current Progress and Future Directions (Review)
Cancer is a leading global cause of mortality, driven by a complex interplay of ...Read more
Lactate as a Central Oncometabolite: Metabolic, Signaling, Immunological, and Epigenetic Mechanisms Driving Tumor Progression (Review)
For decades, lactate was regarded as a simple byproduct of glycolysis, tightly l...Read more
Lactobacillus reuteri DSM 17938 interventions for reduction of crying time in infantile colic and associated fecal microbiome changes: a strain-level systematic review (Review)
Infantile colic is common, distressing, and of uncertain etiology; perturbations...Read more
Large Language Models for Improving the Efficacy and Specificity of CRISPR–Cas Gene Editing: A Technical Landscape (Review)
CRISPR–Cas systems have transformed genome editing, yet in vivo clinic perform...Read more
Lead-oncoMap: Calibratable Multi-Organ Cancer Risk from Chronic Lead Exposure (LeadCaRisk) (Review)
Lead (Pb) remains a pervasive toxicant with no physiological role. Inorganic lea...Read more
Life at the Limits: Microbial Adaptation via Gene Transfer and Epigenetic Control (Review)
Extremophilic microorganisms exhibit exceptional resilience to environmental str...Read more
Liquid Biopsy in Cancer (ctDNA, exosomes, microRNAs): A New Era of Non-Invasive Molecular Diagnostics (Review)
2.1 Need for Non-Invasive Cancer Diagnostics Tissue biopsies remain the gold ...Read more
LncRNAs as clinical treatment opportunities for breast cancer (Review)
Breast cancer is among the most common types of cancer, especially in women all ...Read more
lncRNAs as Emerging Regulators of Cellular Stress Pathways in Cancer Progression and Therapy (Review)
Cancer cells are constantly challenged by stressful conditions such as oxidative...Read more
Longevity and anti‑aging effects of curcumin supplementation (Review)
Introduction: Aging is an irreversible biological process characterized by a dec...Read more
Low Anti-HBc Antibody Prevalence and Non-Detection of HBV DNA in HBsAg-Negative Iranian Blood Donors: A Cross-Sectional Analysis and Review of the Literature (Research Paper)
Background: Occult hepatitis B infection (OBI) refers to the presence of hepatit...Read more
Low-Intensity Focused Ultrasound in Parkinson’s Disease” (Review)
Parkinson’s disease (PD) is a widespread neurodegenerative condition that pose...Read more
Lysine at position 71, Proline at position 74 and Valine at position 11 in the HLA-DRB1 beta chain are associated with Rheumatoid arthritis (Research Paper)
Objective: Rheumatoid arthritis (RA) is a complex multifactorial autoimmune dise...Read more
Machine Learning-Driven Discovery of Differentially Expressed Genes as Potential Breast Cancer Biomarkers (Research Paper)
Breast cancer remains a leading cause of mortality worldwide, with its molecular...Read more
Marine actinomycetes: Important sources for biopharmaceutical compounds (Review)
The oceans are regarded as a crucial and abundant source of new bioactive second...Read more
Mastectomy, Surgial approaches and Clinical results (Review)
Breast cancer is the most prevalent cancer in women and among the leading causes...Read more
Mechanisms of Carbapenem Resistance in Gram-Negative Bacteria and Novel Strategies for Overcoming It (Review)
Carbapenem antibiotics are among the most powerful treatments available for mult...Read more
Medical genetics (Review)
IntroductionMedical genetics is a pivotal branch of medicine that explores the i...Read more
Mediterranean diet intervention to prevent progression of pediatric nonalcoholic fatty liver disease (NAFLD): a systematic review of dietary and lifestyle studies (Review)
Pediatric nonalcoholic fatty liver disease (NAFLD) prevalence is rising in paral...Read more
Melaleuca alternifolia Essential Oil Inhibited Influenza A Virus Replication (Research Paper)
Influenza A virus (IAV) poses an ongoing threat to global health due to its high...Read more
Mental health of the elderly in the face of natural disasters (Review)
Human confrontation and struggle with natural phenomena and unexpected events ar...Read more
Mesenchymal Stem Cells in the Treatment of Type 1 Diabetes Mellitus (Review)
The irreversible loss of the insulin-secreting β cells in the pancreas is a hal...Read more
Meta-Analysis and Bioinformatic Insights into Functional Impacts of Signaling and Carbohydrate Metabolism Gene SNPs in Skin Cancer (Research Paper)
Cutaneous malignancies result from intricate molecular interactions, yet the pre...Read more
Metabolism and metabolic disease (Review)
IntroductionMetabolism encompasses the biochemical processes that sustain life, ...Read more
Methods for controlling hospital infections caused by fungi (Review)
Nosocomial fungal infections are a major issue in healthcare facilities and thei...Read more
Methylated CpG Sites of the RAP1GAP Gene in the Anaplastic Thyroid Carcinoma (Research Paper)
Anaplastic thyroid cancer (ATC) is a rare and extremely aggressive form of thyro...Read more
Micelles in nanomedicine:Innovations in drug delivery, diagnostics, and Non-ionizing therapies for cancer (Review)
1. Introduction Micelles are colloidal aggregates formed by amphiphilic mole...Read more
Microarray-Based Differential Gene Expression and Network Pharmacology Analysis Reveal Therapeutic Targets of Parthenolide in Pancreatic Ductal Adenocarcinoma (Research Paper)
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies, ...Read more
Microbial Determinants of Antidepressant Response: Insights into the Gut–Brain–Drug Axis in MDD (Review)
Major depressive disorder (MDD) is a common and disabling psychiatric illness, m...Read more
Microbial Diversity in Fermented Foods: Health Benefits and Food Safety Perspectives (Review)
Fermentation is one of the oldest and most widely used food-processing technolog...Read more
Microbiological Approaches to Mycotoxin Detoxification in Food: A Review of Biological Methods and Safety Implications (Review)
Mycotoxins are harmful compounds produced by certain fungi, especially Aspergill...Read more
Microbiology and Infectious Diseases (Research Paper)
The importance of researching Elizabethkingis anophelis is exceptionally high du...Read more
Microfluidic Platforms for Nanomedicine and Tumor Modeling in Pancreatic Cancer (Review)
Microfluidic Platforms for Nanomedicine and Tumor Modeling in Pancreatic Cancer ...Read more
Microplastics and the Rise of Antibiotic Resistance: An Emerging Challenge in Spreading Infectious Disease, A Review (Review)
The pervasive contamination of global ecosystems with microplastics (MPs, <5m...Read more
MicroRNA-Guided Oncolytic Virotherapy Targeting Anoikis-Resistant Cancer Cells: A Novel Strategy for Selective Replication and Immune Activation (Review)
Oncolytic viruses (OVs) are engineered or naturally occurring viruses that selec...Read more
MicroRNAs as Biomarkers and Therapeutic Targets in Cancer Prevention and Early Detection (Review)
MicroRNAs (miRNAs) are non-coding RNAs of about 18–25 nucleotides that bind to...Read more
MicroRNAs: Key Regulators and Therapeutic Targets in Melanoma (Review)
Skin cancer of a malignant nature called Melanoma develops from melanocytes whil...Read more
Milk Protein Concentrate Supplementation Improves Anthropometric Parameters, Insulin Sensitivity, and Adipocytokine Balance in Obese Women on a Calorie-Restricted Diet: A Randomized Controlled Trial (Research Paper)
Obesity is closely linked to insulin resistance and dysregulated adipocytokines ...Read more
miR-181a and miR-155 as Prognostic Biomarkers in Pediatric ALL: A Bioinformatic Insight (Research Paper)
Pediatric acute lymphoblastic leukemia (ALL) is the most common cancer in childr...Read more
miRNA Biomarkers, Plasma Extracellular Vesicles, and Breast Cancer Detection (Research Paper)
Mammography screening has improved early breast cancer detection, lowering death...Read more
Modeling Lung Cancer Using Organoids and CRISPR-Cas9 Gene Editing: A Focus on STK11 Mutation (Review)
Lung cancer is the leading cause of cancer-related mortality worldwide, with non...Read more
Modulation of Gut Microbiota by Capsaicin: Implications for Neurochemical Regulation and Behavioral Management in ADHD (Review)
Attention Deficit Hyperactivity Disorder (ADHD) is a prevalent neurodevelopmenta...Read more
Modulation of Hippocampal Oxidative Alterations by Donepezil: Focus on Malondialdehyde and Catalase Activity Following Bisphenol A Exposure (Research Paper)
Bisphenol A (BPA), a common component of microplastics, is widely distributed in...Read more
Modulation of Oxidative Stress and Nrf2 Pathway by Zataria multiflora Essential Oil in Prevention of Selenite-Induced Cataract in Rats: Biochemical and Molecular Insights (Research Paper)
This study investigates the modulation of oxidative stress and the Nrf2 signalin...Read more
Molecular Characterization and Gene Expression Analysis of Spermatogonial Stem Cells in Moghani Sheep (Research Paper)
Most investigations on spermatogonial stem cells (SSCs) have been restricted to ...Read more
Molecular Docking Discovery of Potent Klebsiella aerogenes Urease Inhibitors: Acetyl(sulfanyloxy)azanium vs. N-Methoxyacetamide (Research Paper)
Klebsiella aerogenes is a notable pathogen responsible for severe hospital-acqui...Read more
Molecular docking study of active natural compounds targeting Bcl-2 and ABCB1 proteins in chronic leukemia (Research Paper)
Introduction: Chronic leukemia is a common hematological malignancy in which ov...Read more
Molecular Docking Study of Cinnamaldehyde and Glutamine as Cinnamon Metabolites: Evaluating Thrombin Inhibition Potential and Therapeutic Applications in Coagulation Disorders (Research Paper)
Cinnamon (Cinnamomum verum) contains bioactive compounds like cinnamaldehyde and...Read more
Molecular docking study of resveratrol as LSD1 inhibitor in glioblastoma multiforme (Research Paper)
Background: Glioblastoma multiforme (GBM) is one of the most aggressive malignan...Read more
Molecular dynamics study of G6PD oligomerization: insights into structural stability and subunit interactions (Research Paper)
Cancer is now recognized as the leading cause of death in many countries. One of...Read more
Molecular Markers of Oxidative Stress and Endothelial Activation in Critically Ill COVID-19 Patients: A Comparative Case-Control Study (Research Paper)
SARS-CoV-2, the causative agent of COVID-19, has been shown to interact with ang...Read more
Molecular Signatures of MS: Diagnostic and Prognostic Epigenetic Biomarkers (Review)
Multiple sclerosis (MS) is a long-term autoimmune condition that targets the cen...Read more
mRNA as a new bridge between cancer therapy and medical biotechnology (Review)
Messenger RNA (mRNA) has become one of the most influential concepts in contempo...Read more
mRNA Vaccines for Next-Generation Immunotherapy in Gastrointestinal Cancers (Review)
Gastrointestinal (GI) cancers represent a significant global health burden with ...Read more
mRNA Vaccines: A Game-Changing Platform for Next-Generation Immunotherapy in Gastrointestinal Cancers (Review)
Gastrointestinal (GI) cancers represent a significant global health burden with ...Read more
mRNA-Based Inverse Vaccines for Autoimmune Diseases A Precision Immunomodulatory Approach (Review)
This review explores mRNA-based inverse vaccines as an emerging precision approa...Read more
MSC-Derived Extracellular Vesicles in Inflammatory Signaling Pathways and Therapeutic Potential (Review)
Mesenchymal stem cell (MSC)-derived extracellular vesicles (MSC-EVs) have become...Read more
Multi-Omics Fusion for Precision Endocrinology: An AI-Driven Approach in Polycystic Ovary Syndrome (Review)
Polycystic ovary syndrome (PCOS) is one of the most common and heterogeneous end...Read more
Multiplex Snapshot Minisequencing for the Detection of Common PAH Gene Mutations in Iranian Patients with Phenylketonuria (Research Paper)
Phenylketonuria is a common inborn defect of amino acid metabolism in the world....Read more
Multivalent Vaccines: Advances, Challenges, and Future Directions in Combating Viral Variants (Review)
Viruses with high antigenic variability (e.g., influenza A, SARS-CoV-2) periodic...Read more
Mycobiome in health and disease (Review)
Human body is a reservoir of a large number of microorganisms, their genomes, en...Read more
Myelodysplastic syndromes and acute myeloid leukemia in the elderly: epidemiology, diagnosis and treatment (Review)
Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) are serious blo...Read more
Nano-Enabled Drug Delivery Approaches for Improved Neuropsychiatric Treatment (Review)
Psychiatric disorders including depression, schizophrenia, and anxiety are major...Read more
Nanocarrier Delivery of Postbiotics: A New Frontier in Managing Inflammaging (Review)
Inflammaging is a new concept that seeks to explain the reasons behind the incre...Read more
Nanocarrier-Based Delivery of Doxorubicin in Breast Cancer: Liposomal Formulations and Cardiotoxicity Reduction (Review)
Introduction: Breast cancer remains one of the most prevalent and lethal malign...Read more
Nanocarrier-Based Delivery of Quercetin: A Promising Approach to Overcome Chemoresistance in Gastric Cancer (Review)
Gastric cancer is one of the most common and aggressive malignancies worldwide. ...Read more
Nanocomposite Scaffolds as Advanced Wound Dressings in Skin Cancer and Inflammatory Disorders (Review)
Skin cancer and chronic inflammatory skin disorders represent major global healt...Read more
Nanogels as a Versatile Drug Delivery System for Brain Cancer (Review)
A nanogel is an effective system for delivering drugs locally or systemically th...Read more
Nanomedicine strategies for targeted treatment of cancer stem cells (Review)
Rare subpopulations of cancer cells with the ability to self-renew and initiate ...Read more
Nanoparticle Vaccines and Their Role in Eliciting Robust Immune Responses (Review)
Traditional vaccines, though effective, are limited by poor immunogenicity, inst...Read more
Nanoparticle-Mediated Delivery of Transcription Factors: Advances and Strategies to Enhance Pluripotency Induction (Review)
Induced pluripotent stem cells (iPSCs) have transformed regenerative medicine, e...Read more
Nanoparticle-Mediated Hyperthermia in Cancer Therapy: A Comparative Review of Magnetic, Gold, and Carbon-Based Systems (Research Paper)
The application of elevated temperatures in cancer treatment, a therapeutic appr...Read more
Nanotechnology and gene therapy in breast cancer (Review)
Breast cancer remains one of the most challenging malignancies worldwide, with t...Read more
Nanotechnology and Next-Generation Sequencing in Cancer Prevention, Diagnosis, and Therapy (Review)
Cancer remains a leading cause of morbidity and mortality worldwide, characteriz...Read more
Nanotechnology for Intracellular Drug Delivery: Addressing Undruggable Targets in Glioblastoma (Review)
Glioblastoma, a highly prevalent and aggressive form of brain cancer in adults, ...Read more
Nanovesicle-Magnetic Nanoparticle Hybrid Systems for Cancer Targeting and Non-Invasive Imaging (Review)
Cancer is increasingly acknowledged as a major global health challenge with sign...Read more
Natural Coagulant Hydrogels: Optimizing Herbal Extract-Blended Polymers for Rapid Hemostasis and Wound Healing (Review)
This study explored hydrogels made from cinnamon, yarrow, green tea, and red pep...Read more
Navigating the Storm: A Narrative Review of Human Resource Management Strategies in Times of Crisis (Review)
Crises—economic, natural, political, or health-related—can disrupt organizat...Read more
Neuroblastoma (Research Paper)
Neuroblastoma is a tumor of nerve cell origin that usually occurs in the adrenal...Read more
Neuroimmunology of Vaccination: Implications for Neuroinflammation and Cognitive Health (Review)
Vaccines have transformed public health by preventing infectious diseases; beyon...Read more
Neurological Damage Caused by Herpes Simplex Virus: Neurological Mechanisms, Encephalitis, and the Role of Amygdala and Hippocampal Injury (Review)
Introduction Definition of Herpes Simplex Virus (HSV-1 and HSV-2) Herpes sim...Read more
Neuroprotective Effects of Hydrogen Sulfide on BDNF, IGF-1, and Oxidative Stress in the Hippocampus of High-Fat Diet Rats (Research Paper)
Obesity is a chronic condition that impairs hippocampal function by inducing oxi...Read more
Neuroprotective Effects of Native Iranian Probiotics on Tau Protein Expression and Oxidative Stress Markers in a Rat Model of Alzheimer’s Disease (Research Paper)
Alzheimer’s disease (AD) is one of the most prevalent neurodegenerative disord...Read more
Neuroprotective Potential and Psychiatric Risks of Cannabis: A Differential Risk-Benefit Analysis of THC and CBD in Neurological Versus Psychiatric Disorders (Review)
Cannabis has gone an astonishing path - from an ancient traditional herbal remed...Read more
Neuroscience Perspective on Cognitive Outcomes of Cancer Treatments: A Review of Nano-Medicine and Gene Therapy Studies in Neuroscience (Review)
Cancer-related cognitive impairment (CRCI) refers to a spectrum of cognitive def...Read more
Neurotransmitters and Cognitive Function: Bridging Brain Chemistry and Behavior (Review)
The human brain contains an intricate network of connections that allow learning...Read more
Next-Generation Intelligent Medical Nanorobots and Nanogadgets with Artificial Intelligence for Targeted Cancer Therapy: Simulated Phagocytosis and Apoptosis Induction (Review)
Intelligent medical nanorobots and nanogadgets represent a new generation of tar...Read more
Next-Generation Non-Invasive Prenatal Screening: Advanced cfDNA-Based Platforms and Novel Diagnostic Kits for Early Detection of Aneuploidies and Microdeletion Syndromes (Review)
In recent years, non-invasive prenatal testing (NIPT) based on sequencing of cel...Read more
NF-kB regulates the migration of vascular smooth muscle cells after heparin and ibrutinib treatments. (Review)
The aim of the study was to examine the effect of heparin on the migration and p...Read more
Novel Genetic Clues Linking Endometriosis and Endometrial Stromal Sarcoma: Insights from Whole Exome Sequencing (Research Paper)
Endometriosis and endometrial stromal sarcoma (ESS) are hormonally modulated gyn...Read more
Novel non-pharmacological approaches for stress-induced depression: emphasizing cell-based therapeutic strategies (Review)
Major depressive disorder (MDD) is a prevalent psychiatric condition often trigg...Read more
Novel Strategies for Prevention and Management of Recurrent Urinary and Vaginal Infections in Women of Reproductive Age (Review)
Recurrent urinary and vaginal infections are among the most common health proble...Read more
Nucleic Acid-Based Therapeutics: Translating Genetic Code into Clinical Applications (Review)
Nucleic acids, being the fundamental components of genetic information, have an ...Read more
Nutritional Epigenomics: The Impact of Diet on Epigenetic Regulation and Metabolic Disease Risk (Review)
Nutritional epigenomics is an emerging field that explores how dietary factors i...Read more
Occurrence and Control of Aflatoxins in Pistachios: Microbiological and Post-Harvest Strategies (Review)
Aflatoxins are highly toxic and carcinogenic compounds primarily produced by Asp...Read more
Oncolytic Adenovirus Expressing IL-2: An Emerging Approach for Cancer Immunotherapy (Review)
Cancer immunotherapy has revolutionized cancer treatment, demonstrating remarkab...Read more
Online platform of the prevision of cancer genetics (Research Paper)
Abstract Genetic cancer prevention is one of the most innovative and vital ap...Read more
Optimization of the reaction conditions for the removal of colored impurities in crude heparin using potassium permanganate (Research Paper)
Heparin is one of the most widely used drugs in the world. Heparin is known as a...Read more
Optimizing Nanoparticle Synthesis for Biomedical Applications: A Focus on Morphology, Characterization, and Therapeutic Potential (Review)
introduction: In recent years nanotechnology-based approaches, have demonstrate...Read more
Overcoming drug resistance: thymol and cefotaxime synergy against Acinetobacter baumannii and Klebsiella pneumoniae (Review)
This research evaluates the combined antimicrobial effects of thymol and cefotax...Read more
Overcoming drug resistance: thymol and ceftazidime synergy against Acinetobacter baumannii and Klebsiella pneumoniae (Research Paper)
This research evaluates the combined antimicrobial effects of thymol and ceftazi...Read more
Overview of stem cell therapy (Review)
The definition of stem cells is predicated on two fundamental criteria: first, t...Read more
Palliative Care Standards for Elderly Patients with Chronic Heart Failure at Home (Review)
Chronic heart failure (CHF) remains a leading cause of morbidity and mortality a...Read more
Pan-cytokeratin Expression of Mesenchymal Stem Cells Cultured on Chitosan/Polyvinyl Alcohol Hydrogel Containing Caviar Extract (Research Paper)
The development of wound dressings with optimal properties is crucial for accele...Read more
Pathogens, Infections, and Strategies for Prevention and Treatment (Review)
Pathogens, including bacteria, viruses, prions, parasites, and other microbes, d...Read more
Patient Lift Chair (Research Paper)
Biomedical engineering is an inherently interdisciplinary field emerging from th...Read more
Patients' bone marrow-derived MSCs induce T lymphocytes differentiation into Treg (Review)
Abstract The escape of cancer cells from the immune system is one of the factor...Read more
pH sensitive smart wound dressings for advanced management of diabetic wounds (Review)
Smart dressings with self-adaptive capabilities are able to regulate wound moist...Read more
Phage Therapy in the Antibiotic Resistance Era: A Comprehensive Review of Its Use Against Drug-Resistant Infections (Review)
Antibiotic resistance in infectious disease is now one of the world's most press...Read more
Phage Therapy: An Innovative and Promising Frontier in the Battle Against Antimicrobial Resistance (Review)
Antimicrobial resistance (AMR) stands as one of the most daunting challenges to ...Read more
Pharmacogenetic Approaches to Ovarian Cancer Management (Review)
Due to its asymptomatic early stages and the lack of population-based screening ...Read more
Pharmacogenetic Profile of Common Polymorphisms in Iranian ALL Patients and Their Association with Treatment Response (Research Paper)
Single nucleotide polymorphisms (SNPs) are important for the study of human dise...Read more
Pharmacological Inhibition of BUB1 with BAY1816032 Suppresses Growth and Metastatic Potential in PPGL-Derived Cells (Research Paper)
Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors that...Read more
Physical, Chemical and Microbial techniques for the reduction of biogenic amines in fishery products: A promising strategy in food safety (Review)
Biogenic amines (BAs), identified as serious chemical hazards, were detected in ...Read more
Platinum Nanoparticles A Cutting Edge Nanotherapeutic Strategy to Modulate Oxidative Stress in Lung Cancer (Research Paper)
Lung cancer, particularly non-small cell lung cancer (NSCLC), accounts for 85% o...Read more
Poly (3-hydroxybutyrate)-Collagen/MXene Electrospun Scaffold for Nerve Regeneration: Experimental and Computational Characterization (Research Paper)
Tissue engineering has gained substantial attention in the field of regenerative...Read more
Polymeric Nanoparticles for Targeted Drug Delivery in Cancer Treatment (Review)
Cancer is one of the leading causes of global morbidity and mortality. Chemother...Read more
Postbiotics as Emerging Functional Compounds in the Advancement of Functional Foods (Review)
Food is an essential human need, providing vital nutrients for growth, immune de...Read more
Postbiotics as Emerging Therapeutic Agents: "Industrial-Scale Production and Biomedical Applications" (Review)
Postbiotics refer to non-viable microbial cells, cell components, or metabolites...Read more
potential ability of umbilical cord-derived mesenchymal stem cells in the treatment of premature ovarian failure (Review)
Women of reproductive age may encounter challenges related to infertility or mis...Read more
Potential impact of Nano and Microplastics, as an Emerging Environmental Risk Factor, on Disruption of Human Microbiome Symbiosis and Cancer Development, A Review (Review)
Microplastics (MPs) are major pollutants in the environment, and it is currently...Read more
Potential Risks of Unintended Cellular Expansion in Cell Therapy: Genotoxicity and Tumorigenesis (Review)
Cell therapies, particularly those using gene-manipulated hematopoietic stem/pro...Read more
Potentiation of Chemotherapeutic Sensitivity in Breast Cancer Cells by Eugenol: A Study on MCF7 and MCF7-MX Lines (Research Paper)
Breast cancer is one of the most common and deadly cancers worldwide, posing maj...Read more
Precision Medicine in Colorectal Cancer (Review)
Colorectal cancer (CRC) exemplifies how precision medicine translates molecular ...Read more
Precision Over Power: Representational Fidelity and Network Dynamics in Prefrontal-Hippocampal-Cerebellar Cognitive Control (Review)
Effective cognitive control, encompassing functions from the suppression of unwa...Read more
preconditioning of umbilical cord mesenchymal stem cells with stromal cells -derived factor 1α and its application in animal model of type 1 diabetes (Research Paper)
Stem cell homing to damaged tissues is among a number of main barriers to stem c...Read more
Predicting the Impact of Leptin Gene Promoter SNPs on Gene Expression and its Association with Obesity in Colorectal Cancer (Research Paper)
The simultanous increased prevalence of obesity and colorectal cancer in recent...Read more
Predicting the Structural and Functional Impact of CRISPR-Mediated Mutations: A Review of Computational Strategies for Protein Engineering (Review)
1. Introduction 1.1 CRISPR-Cas9: The Revolution in Precision Genome Editing Th...Read more
Predicting Treatment Response in Vestibular Schwannoma Patients Undergoing Gamma Knife Radiosurgery Using individual and Combined Radiomics and Dosiomics with Machine Learning (Research Paper)
Vestibular schwannoma (VS) is the third most common benign brain tumor. By affec...Read more
Prediction of a miRNA Regulatory Network Targeting LPIN1-Centered Therapeutic Targets Involved in Atherosclerosis Pathogenesis (Research Paper)
Dyslipidemia is a key contributing factor in the onset and progression of cardio...Read more
Prediction of Breast Cancer Metastasis Using Graph Neural Networks: A Comprehensive Study (Research Paper)
Breast cancer metastasis is a major cause of mortality among breast cancer patie...Read more
Preimplantation Genetic Testing for PAH Mutations in Two Iranian Families: A Case Report (Research Paper)
Introduction Phenylketonuria (PKU) is a prevalent autosomal recessive metaboli...Read more
Prevalence of bacterial vaginosis in women with infertility problems among patients referred to medical centers in Shiraz. (Research Paper)
Bacterial vaginosis (BV) is a polymicrobial syndrome described by vaginal itchin...Read more
Prevalence of Headache and Dizziness in Parkinson’s Patients After COVID-19 (Research Paper)
The COVID-19 pandemic, caused by SARS-CoV-2, has posed unprecedented challenges ...Read more
Preventing PI3K/AKT/mTOR pathway by nanoparticle loaded inhibitors: a promising approach in cancer therapy (Review)
The PI3K/AKT/mTOR signaling pathway plays a central role in regulating cancer ce...Read more
Probiotics and their role in promoting health and strengthening the immune system (Review)
Probiotics are a combination of live beneficial bacteria or yeasts that naturall...Read more
Probiotics as Adjunct Therapy in Bacterial Infections: A Systematic Review of Clinical Evidence (Review)
The emergence of antibiotic resistance and dysbiosis associated with antibiotic ...Read more
Programmable PEG-rGO nanocarriers for RNP-mediated adenine base editing of TP53 in patient-derived lung adenocarcinoma models (Research Paper)
Lung adenocarcinoma (LUAD), the predominant subtype of non–small cell lung can...Read more
Promising Approaches in Modeling and Treating Alzheimer’s Disease Using Stem Cell and Bioprinting Technologies (Review)
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that result...Read more
Prostate Cancer Grading Using mpMRI-based Radiomics and Machine Learning (Review)
Prostate cancer diagnosis still poses a major issue, requiring correct grading t...Read more
Protective effect of lycopene on inflammatory factors and total antioxidant capacity of sperm in Asthenozoospermic Men During Freezing-Thawing (Research Paper)
Sperm cryopreservation, a key technique in assisted reproductive technology, oft...Read more
Protective Effects of Ferula assa-foetida Aqueous Extract on Cardiovascular Responses in L-NAME–Induced Hypertensive Rats (Research Paper)
Hypertension is a major global health concern and a leading risk factor for card...Read more
Protective Effects of Gut Microbial Metabolites SCFAs, H2S, Polyamines, and Polyphenols on Cardiovascular Health (Review)
The gut microbiota also produces metabolites with protective effects against car...Read more
Protective role of papaverine against freeze-thaw-induced damage in sperm of asthenozoospermic men: Regulation of apoptosis-related genes (Research Paper)
Asthenozoospermia is one of the most common causes of male infertility and is of...Read more
Protective Role of Simvastatin in Modulating Nitrite Levels and Enhancing Hippocampal Superoxide Dismutase Activity in Bisphenol A-Treated (Research Paper)
Bisphenol A (BPA), a known endocrine disruptor, has been implicated in inducing ...Read more
Radiogenomics Biomarkers in Cervical Cancer: A Comprehensive Review of Prognostic Applications (Review)
Cervical cancer remains a major global health challenge, particularly in low- an...Read more
rAmuc_1100: A Novel Postbiotic Candidate Superior to Metformin in a Diabetic Mouse Model (Research Paper)
Akkermansia muciniphila, a gut bacterium known for degrading mucin, has recently...Read more
Recent Advances in Gene Therapy for Inherited Genetic Disorders: From Clinical Applications to Translational Challenges and Future Perspectives (Review)
Genetic illnesses caused by parent-to-offspring transmission from mutation of an...Read more
Recent Advances in Molecular Imaging Biomarkers for Monitoring Cancer Immunotherapy Response (Review)
Cancer immunotherapy has transformed oncology, but monitoring treatment response...Read more
Recent Advances in Systemic Therapy for Hepatocellular Carcinoma (Review)
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality wo...Read more
Recombinant Drugs and Their Global Market (Review)
Recombinant drugs, created through recombinant DNA technology, are revolutionizi...Read more
Reduced GLT8D2 Expression Predicts Survival and Metastasis in Papillary Thyroid Carcinoma (Research Paper)
Papillary thyroid carcinoma (PTC) is a prevalent form of thyroid malignancy. The...Read more
Regulatory Role of Donepezil on Hippocampal Nitro-Oxidative Markers Following Bisphenol A Exposure (Research Paper)
Bisphenol A (BPA), a widely used plastic-derived compound, disrupts cellular red...Read more
Relationships between taurine-conjugated bile acids and gut microorganisms and ulcerative colitis (UC), colon cancer, and inflammatory bowel disease (IBD) (Review)
The prevalence of inflammatory bowel disease (IBD), a chronic, idiopathic gastro...Read more
Restless Leg Syndrome in Elderly People with High Blood Pressure and Diabetes: Factors Affecting It, A Review Study (Review)
In recent years, the number of elderly people with high blood pressure and diabe...Read more
Review of the Relationship Between Diet, Nutrient Intake, and Lifestyle Factors with HPV Infection: A Narrative Review (Review)
Human papillomavirus (HPV) is a significant global public health challenge linke...Read more
Review of Using Artificial Intelligence to Detect and Track HIV in Patients with COVID-19 (Review)
The overlapping burden of HIV and COVID-19 poses significant challenges for heal...Read more
Review on the antibacterial dental implants: emerging strategies in reducing side effects (Review)
Dental implant has siezed great attention in recent years and bacterial infectio...Read more
Review The role of CeRNA in cancer development and progression (Review)
In mammals, a large part of the gene expression products are non-protein-coding ...Read more
Revolutionizing Organ Transplantation Using the Power of Artificial Intelligence (Review)
One of the mainstays of contemporary medicine is organ transplantation, which pr...Read more
Robotic Surgery for Endometriosis (Review)
Endometriosis is a common chronic inflammatory disorder in women, characterized ...Read more
Role of Copy Number Variations in Neurodevelopmental Disorders (Review)
Neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD), i...Read more
Role of CRISPR-Cas9 Genome Editing in Personalized Treatment of Rare Genetic Disorders: A Case Study on Cystic Fibrosis (Review)
Rare genetic disorders affect over 400 million people worldwide, with CF as a le...Read more
Role of Extracellular Vesicles in Ovarian–Uterine Communication: Emerging Messengers in Female Fertility (Review)
Effective communication between the ovary and uterus is fundamental to reproduct...Read more
Role of H3K4me3 in Oncogene Activation in Melanoma Cells (Research Paper)
Melanoma is one of the deadliest forms of skin cancer, with its global incidence...Read more
Role of Lactobacillus rhamnosus GG in Modulating Immune Responses in Pediatric Food Allergy (Review)
Food allergy represents one of the most prevalent non-communicable immunological...Read more
Role of Liquid Biopsy in Early Cancer Detection and Monitoring: Advances in microRNAs and Circulating Tumor DNA (Review)
Liquid biopsy is a major breakthrough in cancer care. It allows for a non-invasi...Read more
Scientific and Technical Evaluation of Behina Fabric Stretcher: A Novel Approach to Localizing Rescue and Relief Equipment” (Research Paper)
The transfer of patients from the site of an incident to healthcare facilities c...Read more
Scientific Evidence on the Link Between Assisted Reproductive Technology and the Risk of Female Cancers (Review)
introduction Infertility is a global concern, and the utilization of assisted r...Read more
Screening of Tuberculosis-Suspected Subjects Using Real-Time PCR (TaqMan) in Northeastern Iran (Research Paper)
Purpose: Effective and timely tuberculosis (TB) treatment depends on rapid relia...Read more
Severe Combined Immunodeficiency Syndrome (SCID) (Review)
evere Combined Immunodeficiency Syndrome (SCID) encompasses a group of rare gene...Read more
Sex-Based Analysis of Common Polymorphisms in Chronic Myeloid Leukemia within the Iranian Genomic Profile and Assessment of Adverse Effects of Domestically-Developed Drugs (Research Paper)
Side effects of drugs are one of the problems in the treatment of patients with ...Read more
Shingle vaccination and treatment review article (Review)
Shingles is a viral disease characterized by a painful rash on two side of the ...Read more
Skin and Gut Microbiota in Psoriasis: A Narrative Review of Their Interconnected Roles in Disease Progression (Review)
The skin offers an immunological and physical barrier to the outer environment a...Read more
Smart Alerts, Safer Communities: The Role of Mobile Warning Applications in Natural Disaster Management – A Narrative Review (Review)
The rising occurrence of natural disasters necessitates effective crisis managem...Read more
Smart Microchips in Human Organs: A Biomedical Approach to Early Detection and Prevention of Cancer (Review)
In recent decades, biomedical engineering has witnessed transformative progress ...Read more
Smart Probiotic-NanoAntibiotic Systems: Innovative Strategies for Combating Multidrug-Resistant Pathogens (Review)
Antimicrobial resistance (AMR) has become an alarming global health crisis, unde...Read more
Some biological effects of green nanosynthesis: zinc nanoparticles coated with Moringa oleifera extract (Review)
Moringa oleifera (MO), a plant from the Moringaceae family, is a major crop in A...Read more
Stem Cell Signaling in Reproductive Medicine: Potential for Treating Infertility (Review)
Infertility is a complex condition that affects nearly 15% of couples worldwide,...Read more
Stem Cell-based Treatments for Parkinson's Disease (Review)
Parkinson’s disease (PD) ranks as the second most prevalent neurodegenerative ...Read more
Stem cells and the ommaya reservoir: Is it an effective strategy for treating Alzheimer's disease? (Review)
Alzheimer's disease is a progressive neurodegenerative disorder that gradually c...Read more
Studies on activity of executioner caspase enzymes in formalin-fixed tissue samples (Research Paper)
Apoptosis, or programmed cell death, is a crucial physiological process that pla...Read more
Study of common CLL cancer morphisms in Iranian genome profiles and side effects of indigenous drugs in Iran (Research Paper)
Chronic lymphocytic leukemia (CLL) is a common hematologic malignancy influenced...Read more
Study of common polymorphisms in melanoma cancer in Iranian genetic profiles and drug selection with minimal side effects (Research Paper)
Melanoma is one of the most aggressive and life-threatening forms of skin cancer...Read more
Study of common polymorphisms in melanoma skin cancer by age in Iranian genetic profiles and study of side effects of chemotherapy drugs (Research Paper)
Melanoma is a highly aggressive cancer that originates from melanocytes and is i...Read more
Study of Interleukin 27 Gene Polymorphism in rs26528 Position in southern women in Iran with Infertility (Research Paper)
Infertility is a condition affecting many women worldwide. Various factors contr...Read more
Study of synergize of the chitosan hydrogel in conditioned media on differentiation of Mesenchymal stem cells for skin tissue engineering (Research Paper)
Nowadays skin injuries remain a big challenge in regenerative medicine. Over the...Read more
Study of the antibiotic resistance pattern in Staphylococcus aureus bacteria isolated from urinary tract infections in women referred to Fajr Clinical Laboratory in Oshnavieh County during the years 2021-2024 (Research Paper)
Urinary tract infections are the most common bacterial infection in women. They ...Read more
Study of the frequency of Staphylococcus aureus in urinary tract infections in patients residing in nursing homes and referring to medical centers in Khorramabad city (Research Paper)
Background and Aim : Urinary tract infection is one of the most common acquired ...Read more
Study of the susceptibility of bacteria isolated from urinary tract infections to ciprofloxacin (Research Paper)
Nowadays, antibiotic resistance is increasing due to overuse, and this issue has...Read more
Study on the Relationship between Abortion Rates and Total Fertility Rates in Selected Countries Worldwide (Review)
Introduction Abortion is one of the complex and influential issues in the field...Read more
Studying the association of LncRNA GAS6-ASI expression changes with EGER gene exon 21 mutations and its relationship with prognosis in Iranian colorectal cancer patients (Research Paper)
Colorectal cancer are a prevalent cancer type. Identifying biomarkers for preven...Read more
Studying the effect of simulated Mars, Moon, and Earth soil on Florida oyster mushrooms (Review)
Developing sustainable food systems for long-term space missions has become a pr...Read more
Studying the gene expression differentiation between mesenchymal stem cells and osteogenics (Research Paper)
The investigation of disparities between gene expression profiles in mesenchymal...Read more
Super-Enhancer-Driven Network Identifies MIR4461 and MIR1204 Regulators in Metastatic Prostate Cancer. (Research Paper)
Super-enhancers are large clusters of regulatory elements bound by bromodomain p...Read more
Swimming Combined with Estrogen Reduces Serum IGF-1 Levels and Blood glucose Induced by a High-Fat Diet via Modulating the Hepatic Expression of miR-130a-3p and miR-29a in a Postmenopausal rat model. (Research Paper)
This study was designed to determine the effects of swimming (SWIM) and E2 (alon...Read more
Synergistic Antibacterial Effects of Zataria multiflora essential oil Against MRSA (Research Paper)
Methicillin-resistant Staphylococcus aureus (MRSA) is a significant public healt...Read more
Synergistic Anticancer Effects of Berberine and Cisplatin Through Upregulation of ATG7-Mediated Autophagy and Apoptosis in Bladder Cancer Cell Lines (Research Paper)
Bladder cancer is a prevalent urological malignancy with high recurrence rates a...Read more
Synergistic Effects of Cold Atmospheric Plasma and Nanomedicine in Reactive Oxygen Species-Based Cancer Therapy (Review)
Cancer remains one of the leading causes of global mortality, and current therap...Read more
Synergistic effects of ursolic acid and selenium nanoparticles on the inhibition of metastasis-associated gene expression in MDA-MB-231 breast cancer cells (Research Paper)
Breast cancer, accounting for 11.7% of all cancer cases in 2020 according to the...Read more
Synthesis of Niosomes Loaded with Temozolomide and Quercetin and Investigating its Effect on Cell Proliferation and SOD activity in Brain Tumor Cell line U251 (Research Paper)
Glioblastoma is one of the most aggressive and lethal primary brain tumors, char...Read more
Syphilis: A Persistent Global Challenge and Vaccine Development Perspectives (Review)
Syphilis is a chronic, multi-stage sexually transmitted infection caused by Trep...Read more
Systematic Review of the relationship between genes and climate change in Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis (Review)
Climate change has been implicated as an environmental risk factor for neurologi...Read more
Systematic Review on the Impact of Microplastics on Cognitive and Physical Health in Elderly Populations (Review)
Environmental contamination with microplastics has emerged as a pervasive and co...Read more
Targeted Anticancer Effects of Paclitaxel-Loaded Magnetite Nanoparticles on Breast Cancer Cell (Research Paper)
Breast cancer remains a serious global health challenge, with its complex pathog...Read more
Targeted Delivery of siRNA via Ligand-Modified Lipid Nanoparticles for the Treatment of HCC (Review)
Hepatocellular carcinoma (HCC) is the most prevalent form of liver cancer, accou...Read more
Targeted Drug Delivery Systems Integrating Nanotechnology, Quantum Biophotonics, and Precision Medicine: Design, Applications, and Clinical Perspectives (Review)
Targeted Drug Delivery Systems (TDDS) represent a transformative approach in mod...Read more
Targeted Functional Correction of PTEN, TP53, KRAS, and ARID1A Mutations in Uterine and Vaginal Cancers via CRISPR/Cas9: Links to Key Cytokines (IL-6, TNF-, IFN-, IL-10), Sex Hormone Profiles (Estradiol, Progesterone, FSH, LH), Immune Checkpoints and CD8+ Response, with Advanced Tumor Microenvironment Modeling Using Integrative NGS, Bulk and Single-cell Multi-Omics, Gene and Engineered Cell Therapies (Review)
Uterine cancers that occur during pregnancy represent a rare but clinically comp...Read more
Targeted therapies for breast cancer (Review)
Breast cancer remains a formidable contender in the global health challenge land...Read more
Targeting Metastatic Suppressor Genes: A New Frontier in Cancer Therapy (Review)
Metastasis suppressor genes (MSGs) are notable for the ability to block the deve...Read more
Targeting PD-1⁺ NK Cells and JAK/STAT-Mediated Chemoresistance in High-Grade Serous Ovarian Carcinoma: Insights from Spatially Resolved Omics (Review)
High-grade serous ovarian carcinoma (HGSC) is one of the most aggressive gynecol...Read more
Technology-Assisted Approaches in Women’s Reproductive Health: A Systematic Review of Recent Evidence (2022–2025) (Review)
Recent advances in technology-assisted care, particularly artificial intelligenc...Read more
The Anti-inflammatory Effect of Nano particles of Chitosan-Saffron on Heart Failure (Research Paper)
Herbal medicine is considered a valuable source to support traditional medicine....Read more
The Application of Artificial Intelligence in Rehabilitation and Elderly Care: A Systematic Review and Novel Outcomes (Review)
With the global aging population, the demand for intelligent systems in elderly ...Read more
The Application of Artificial Intelligence in the Prediction and Management of Infertility in Women with Polycystic Ovary Syndrome (PCOS): A Systematic Review (Review)
Polycystic Ovary Syndrome (PCOS), the most common endocrine disorder among women...Read more
The application of next-generation sequencing technologies in newborn screening (Review)
Newborn screening (NBS) programs have facilitated the early diagnosis, proper in...Read more
The Architectonics of Life: A Review of 3D Bioprinting for Tissue Engineering (Review)
Tissue and organ shortages remain one of the most pressing challenges in modern ...Read more
The Biological Mechanisms of Chrysin in Bone Regeneration, Density, and Mass Enhancement: A Systematic Review (Review)
Bone regeneration and remodelling are fundamental processes that ensure the inte...Read more
The complexities of biofilm: novel applications of artificial intelligence in microbial identification and control (Review)
Biofilms are complex communities of microbes that adhere to surfaces and pose ma...Read more
The Connection Between Esophageal Cancer and the Hexokinase Enzyme (Research Paper)
Esophageal cancer (EC) is an aggressive malignancy with increasing incidence and...Read more
The Critical Role of Hexokinase in Hematological Malignancies and Emerging Therapeutic Drugs (Review)
Hematological malignancies like leukemia, lymphoma, and multiple myeloma are the...Read more
The effect of addictive substances on the fetal central nervous system (Review)
Exposure to addictive substances during pregnancy is a major global and growing ...Read more
The effect of antibiotic use on the gut microbiota (Review)
The human gut is a complex ecosystem and plays a key role in human health, metab...Read more
The Effect of Coffee Consumption on Prostate Cancer in Adult Men (Review)
Prostate cancer is the second most common cancer among men worldwide. Its incide...Read more
The effect of genistein supplementation on the gut microbiome and its role in inhibiting breast tumors (Review)
Breast cancer (BC) is the most common cancer among women globally, leading to hi...Read more
The Effect of Human Umbilical Cord Mesenchymal Stem Cells- Derived Conditioned Medium on Human Liver Cancer Cell Line: Provoking or Preventing Progression (Research Paper)
Background: Hepatocellular carcinoma is the most common liver cancer with a high...Read more
The effect of movement therapy on depression in elderly people with leukemia (Research Paper)
Cancer is the third leading cause of death and one of the leading causes of chro...Read more
The Effect of Nursing Interventions Based on Multimodal Pain Assessment on Chronic Pain Management in Patients with Metastatic Cancer (Review)
Chronic pain is among the most debilitating symptoms faced by patients with meta...Read more
The effect of probiotic supplementation on the intestinal microbiota of premature infants (Review)
According to the World Health Organization (WHO) data, more than 10 percent of b...Read more
The Effect of Probiotics on the Gut Microbiome and Depression (Review)
Depression is among the most frequent mental disorders, ranking second according...Read more
The Effect of Retinoic Acid on the Expression of Nestin, GATA Binding Protein 3, Neurogenin 1, and Microtubule-Associated Protein 2 Markers in Mesenchymal Stem Cells Derived from Human Adipose Tissue (Research Paper)
Hearing loss in developing countries drives interest in stem cell therapies, tho...Read more
The Effect of Seizures on Sperm Parameters, Chromatin Maturation, and DNA Damage via Hypothalamic-Pituitary-Gonadal Axis Dysfunction in Men (Research Paper)
Seizures, as a neurological disorder, can impair male reproductive health. These...Read more
The effect of signaling pathways on the induction and inhibition of apoptosis in cervical cancer (Review)
Cervical cancer (CC) is the most commonly diagnosed malignancy among women world...Read more
The effect of the vaccines on the treatment of cancer and prevention of relapse in people with previous HPV infection (Review)
Human papillomavirus (HPV) is the most prevalent sexually transmitted virus, wit...Read more
The effects of electromagnetic waves on cancer cells (Review)
The use of electromagnetic waves in cancer treatment has gained significant atte...Read more
The Effects of Empagliflozin on inflammatory markers in women with polycystic ovary syndrome (Research Paper)
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among wom...Read more
The Efficacy of Lactobacillus and Bifidobacterium in Depressive: A Brief Review (Review)
Depression is one of the most common mental disorders, affecting a significant n...Read more
The Emerging Role of Bioceramics and Microrods in Cancer Treatment: A Comprehensive Review (Review)
Cancer remains one of the leading causes of death worldwide, and despite signifi...Read more
The Emerging Role of Gut Microbiota in Cardiovascular Health: From Inflammation to Atherosclerosis (Review)
In recent years, the gut microbiota has gained significant attention as a key mo...Read more
The Emerging Role of Stem Cells in Melanoma Therapy: Opportunities and Challenges (Review)
Melanoma is the most aggressive form of skin cancer, accounting for the majority...Read more
The Evolving Landscape of Molecular Medicine: From Bench to Bedside (Review)
Molecular medicine, often referred to as "tomorrow's medicine," is res...Read more
The Function of Exosomes in the Early Diagnosis of Urological Cancers (Review)
Exosomes are small extracellular vesicles that are secreted by donor cells, func...Read more
The Future of Simulation in Medical Education (Review)
Simulation has emerged as an innovative and interactive educational strategy tha...Read more
The Future of Targeted Gene-Based Therapies and Biomarkers in Parkinson’s Disease” (Review)
Parkinson’s disease (PD) is defined by progressive motor impairment and a vari...Read more
The genetic and epigenetic impact of nutrition on cancer (Research Paper)
Single nucleotide polymorphisms (SNPs) are the most common genetic variations in...Read more
The Genital Microbiome and Its Association with Infertility in Men and Women (Review)
The Genital Microbiome and Its Association with Infertility in Men and Women Th...Read more
The Gut Microbiome and Type 2 Diabetes: Mechanisms and Therapeutic Implications (Review)
The gut microbiome, which is composed of trillions of microorganisms, is increas...Read more
The Gut Microbiota-Infertility Axis: A Review of Potential Mechanisms and the Therapeutic Promise of Probiotics like Mekel Probiotic (Review)
Infertility, defined as the failure to conceive after 12 months of regular unpro...Read more
The Hidden Helpers: Understanding the Human Microbiome (Review)
The gut microbiome is the community of microorganisms (bacteria, viruses, fungi)...Read more
The Human Microbiome in Cancer: Roles in Onset, Progression, and Therapeutic Response (Review)
In recent years, the role of the human microbiome in the onset, progression, and...Read more
The impact of biomarkers on the early diagnosis and prediction of human lung cancer (Review)
Lung cancer is the leading cause of cancer-related mortality worldwide, accounti...Read more
The impact of exposure to microplastics on ovarian function, sex hormones, and fertility in women (Review)
Microplastics (MPs) are synthetic particles ranging in size from 1 μm to 5 mm t...Read more
The impact of Microbial Transglutaminase Enzyme on dairy products in the dairy industry. (Review)
Microbial Transglutaminase Enzyme (MTG), known as EC 2.3.3.13, is extracted and ...Read more
The Impact of Nuclear Energy in Medicine (Nuclear Medicine) for the Diagnosis and Treatment of Cancer (Review)
The powerful presence of nuclear energy is considered one of the essential pilla...Read more
The Impact of Omega-3 Rich Foods on Human Health (Review)
Omega-3 fatty acids, essential polyunsaturated fats, play a crucial role in main...Read more
The impact of rhabdomyoma tumors in children and infants in different communities (Review)
Cardiac tumours are benign or malignant neoplasms arising primarily in the inner...Read more
The Impact of Seizures and Antiepileptic Drug Treatments on Oocyte Quality in Women Undergoing In Vitro Fertilization (IVF) (Research Paper)
Infertility in women with epilepsy is a complex clinical challenge that can resu...Read more
The Impact of Space and Microgravity on Cancer Cell Growth (Review)
Space exploration creates unique conditions such as radiation, circadian disrupt...Read more
The Impact of Staphylococcus aureus Gut Colonization on Genome Instability and Inflammatory Bowel Disease (IBD) Pathogenesis: A Narrative Review (Review)
Staphylococcus aureus (S. aureus) is a highly adaptable and virulent pathogen, h...Read more
The importance of assessing DNA methylation in genomic imprinting (Review)
Genomic imprinting is the process of gene silencing through DNA methylation at i...Read more
The Importance of Understanding Teratogenic Viral Risks During Pregnancy (Review)
Emerging viral infections pose a significant threat to pregnant women and their ...Read more
The influence of genetic polymorphisms on drug side effects in patients thalassemia major with Iranian genetic profiles (Research Paper)
Thalassemia is a common blood disorder with autosomal recessive inheritance that...Read more
The Interconnection Between Fatty Acids and Neuroplasticity: Implications for the Prevention of Cognitive Decline (Review)
Cognitive decline, particularly in aging populations, poses a significant public...Read more
The Interplay Between the Human Microbiome and Immune Response in Infectious Diseases: Insights and Emerging Perspectives (Review)
Infectious diseases remain one of the most critical global health challenges, ca...Read more
The Interplay Between the Immune System and Cognitive Function: Mechanisms and Implications (Review)
The brain and spinal cord (the CNS), like other organs, have their own immune sy...Read more
The Interplay of Genetic Polymorphisms and Herbal Medicine: A Review of Pharmacogenomic Influences on Phytotherapy (Review)
The use of herbal medicines(HMs) has seen a global resurgence due to their perce...Read more
The Microbiome Revolution: Bridging Gut Health, Mental Well-Being, and Immunity (Review)
The landscape of biomedical science is currently being reshaped by a groundbreak...Read more
The Oncogenic Role of lncRNA-PNUTS in Modulating the miR-145-5p/EGFR Axis in Glioblastoma (Research Paper)
Introduction: Glioblastoma multiforme (GBM) is the most aggressive and lethal f...Read more
The potential effect of photobiomodulation on oral mucositis induced by head and neck radio-chemotherapy: A literature review (Review)
Oral mucositis (OM) is a frequent and debilitating side effect of head and neck ...Read more
The potential of CAR T-cell therapy in the treatment of autoimmune diseases (Review)
Introduction: Autoimmune diseases arise when the immune cells malfunction and t...Read more
The Prevalence, Risk Factors, and Interventions for Frailty Syndrome in Older Adults: Systematic Review and Meta-Analysis (Review)
Frailty syndrome is a common geriatric condition characterized by decreased phys...Read more
The Prognostic Impact of ASXL1 Mutations in Myeloproliferative Neoplasms: A Systematic Review (Review)
Myeloproliferative neoplasms (MPNs) are clonal hematological disorders character...Read more
The protective effects of nicotine, with and without blockade of peroxisome proliferator-activated receptor gamma (PPARγ), on lung injury induced by saline lavage in rats (Research Paper)
Our previous research demonstrated that nicotine, an α7 nicotinic acetylcholine...Read more
The Regulatory Nexus: Unraveling the E6/E7-hnRNP Axis in Orchestrating Transcriptional Escape and PD-L1-Driven Immune Evasion in High-Risk HPV Carcinogenesis (Review)
Despite progress in identifying the molecular targets of E6 and E7, the transfor...Read more
The relation between Colorectal cancer and liver metastasis (Review)
Colorectal cancer (CRC) is a widespread malignant tumor globally, ranking third ...Read more
The relationship between microbiology and women's reproductive health and the role of the microbiome in reproductive health (Review)
The microbiome, the collection of microbes that live in our bodies, plays a cruc...Read more
The Relationship Between the Receptor Role of Sortilin on the Cell Surface and Atherosclerosis in Hypercholesterolemic Conditions (Review)
Atherosclerosis is a chronic and progressive cardiovascular disease characterize...Read more
The Reproductive Microbiome: Implications for Fertility and Assisted Reproduction: A short review (Review)
The reproductive microbiome has recently emerged as a crucial determinant of fer...Read more
The Role and Function of Dialysis Machines in Kidney Failure Treatment (Research Paper)
The kidneys are vital organs responsible for filtering waste products from the b...Read more
The Role of Neuroimmunological Factors, Oxidative Stress, HPA Axis, Neurogenesis, Decision-Making, Chronic Pain, and EEG in Depression: A Comprehensive Review (Review)
Major Depressive Disorder (MDD) is recognized as a serious and common neurologic...Read more
The Role of Artificial Intelligence Algorithms in Endometrial Cancer Prediction: A Systematic Review (Review)
Endometrial cancer is among the most common gynecological malignancies, and earl...Read more
The Role of Bilirubin in Preventing Ethanol-Induced Oxidative Damage: An In Silico and In Vitro Investigation (Review)
Alcohol consumption is one of the effective factors in the liver toxicity. Bilir...Read more
The Role of Biofilms in Antibiotic Resistance and Associated Therapeutic review article (Review)
Biofilms are a spontaneously formed slimy matrix of extracellular polymeric sub...Read more
The Role of Cell Therapy in the Treatment of Retinitis Pigmentosa (RP) (Review)
Retinitis pigmentosa (RP) is a group of inherited retinal dystrophies that invol...Read more
The Role Of Circular RNA in Oral Cancer (Review)
Circular RNAs (circRNAs) are a novel type of RNA that, unlike linear RNAs, form ...Read more
The Role of CRISPR-Cas9 in Modern Medicine and Genetic Disease Treatment (Review)
Genetic disorders, long considered untouchable at their molecular roots, are now...Read more
The Role of Electrical Stimulation in Enhancing Functional Efficiency of 3D Neuromuscular Models (Review)
Neural-muscular tissue engineering in regenerative medicine requires the functio...Read more
The role of exercise and sports activities in MS and Parkinson's disease (Review)
As the population ages, the prevalence of neurological diseases such as MS and P...Read more
The Role of Genetic Polymorphisms in Resistance and Susceptibility to Infectious Diseases (Review)
Infectious diseases continue to be a major global health challenge, with signifi...Read more
The Role of Genetic Testing in Personalized Cancer Therapy (Review)
Personalized treatment, sometimes also known as precision oncology, has revoluti...Read more
The Role of Gut Microbiome in Cancer Treatment: Implications for Immunotherapy and Cancer Therapy Responses (Review)
The human gut microbiome, consisting of trillions of microorganisms, plays a cru...Read more
The Role of Gut Microbiome in Parkinson’s Disease Progression: From Dysbiosis to Novel Therapeutics (Review)
Parkinson’s disease (PD) is a progressive neurological disorder characterized ...Read more
The role of gut microbiome in regulating immune response and treating or controlling the autoimmune disease IBD (Research Paper)
The gut microbiome is a vast collection of bacteria, viruses, fungi, and other m...Read more
The Role of Gut Microbiome in the Prevention and Progression of Infectious Diseases: A Systematic Review (Review)
The human gut microbiome consists of a complex community of trillions of microor...Read more
The role of Hexokinase Enzymes in Liver Cancer Metabolism (Research Paper)
Liver cancer is the sixth most commonly diagnosed cancer and the third most comm...Read more
The role of HPV vaccine in the prevention and treatment of cervical cancer: a systematic review. (Review)
Cervical cancer is the second leading cause of cancer death in women and the fou...Read more
The Role of Immuno-Biotechnology in Reducing Recurrent Pregnancy Loss: Focus on IVIG and Immune Biomarkers (Review)
Recurrent pregnancy loss (RPL), defined as two or more consecutive miscarriages,...Read more
The Role of Lipid Metabolism in Leukemia: A Review of Lipid Biosynthesis and Signaling Mechanisms (Review)
Lipid metabolism is a fundamental cellular process that plays a crucial role in ...Read more
The Role of Long Non-Coding RNAs in Modern Therapeutics: Challenges and Prospects (Review)
With the advancement of gene therapies and their entry into clinical trials, non...Read more
The Role of Mesenchymal Stem Cells in Modulating Immune Response in Regenerative Medicine (Review)
Regenerative medicine, a rapidly evolving field, aims to restore tissue and orga...Read more
The Role of Metagenomic Next-Generation Sequencing (mNGS) in Infectious Disease Diagnosis (Review)
According to recent studies, around 60 million deaths worldwide occur every year...Read more
The role of metal nanoparticles in photodynamic cancer therapy (Review)
Photodynamic therapy (PDT) is a non-invasive and selective form of light therapy...Read more
The Role of Microbiota-Derived Epigenetic Metabolites in Personalized Medicine: Focus on Alzheimer’s and Parkinson’s Diseases (Review)
The gut microbiota consists of millions of microorganisms that produce diverse m...Read more
The role of music therapy and artistic interventions on improving episodic memory and quality of life in elderly with vascular dementia (Review)
Vascular dementia (VaD), a prevalent dementia subtype in elderly individuals, pr...Read more
The Role of Musical Training and Motor Imagery in Enhancing Neuroplasticity and Improving Cognitive and Motor Functions: A Narrative Review Based on fMRI Evidence (Review)
Neuroplasticity refers to the brain’s capacity for structural and functional r...Read more
The Role of Nanocurcumin in Cancer Therapy: A Review of Preclinical Efficacy Across Different Malignancies (Review)
Curcumin, a polyphenol derived from Curcuma longa (Turmeric), exhibits potent an...Read more
The role of non-coding RNAs in stemness of bladder cancer cells (Review)
In 2025, more than 84,000 new cases of bladder cancer were diagnosed in the Unit...Read more
The Role of Nutrition, Lifestyle, and Physical Activity in the Prevention of Common Cancers: A Review of Recent Evidence (Review)
With over 10 million deaths annually worldwide, cancer is one of the biggest pub...Read more
The Role of Preconception Education in Preventing Reproductive Disorders (Review)
Reproductive disorders are among the major challenges in women’s health during...Read more
The Role of Probiotics in the Prevention and Management of Urinary Tract Infections Induced by Streptococcus viridans (Review)
Urinary tract infections (UTIs) are among the most common bacterial infections a...Read more
The role of probiotics in the treatment of bacterial vaginosis: A review of evidence and strategies (Review)
Bacterial vaginosis (BV) is the most widespread form of vaginal dysbiosis, affec...Read more
The Role of Regulatory T Cells (Tregs) in Immune Homeostasis and Prevention of Inflammatory Diseases (Review)
Regulatory T cells (Tregs) are a specialized subset of CD4+ T lymphocytes charac...Read more
The Role of Seafood Diet in Improving Fertility Outcomes and Metabolic Markers in Women with Polycystic Ovary Syndrome: A Narrative Review (Review)
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders i...Read more
The Role of Social Media Platforms in Medical Education: A Narrative Review (Review)
The rapid expansion of social media has reshaped communication, collaboration, a...Read more
The role of stem cells in cancer treatment (Review)
This article reviews stem cells, cancer biology, and the role of stem cells in c...Read more
The role of the androgen receptor in endurance training-induced soleus muscle hypertrophy (Review)
The androgen receptor (AR) is known as a key agent in regulating muscle response...Read more
The Role of the CRISPR-Cas System in Antimicrobial Resistance (Review)
Antibiotic resistance is a serious worldwide issue brought on by the battle betw...Read more
The Role of the Gut Microbiome and Probiotics in Colorectal Cancer: A Step Toward Early Diagnosis (Review)
Background: Colorectal cancer (CRC) remains a major contributor to cancer-rela...Read more
The Role of the Microbiome in Personalized Medicine: Bioinformatic Analysis of Microbiome Data to Enhance Immunotherapy Response (Review)
The intestinal microbiome, a complex ecosystem, is an important regulator of the...Read more
The Role of Vitamin D in the Immune System and Autoimmune Diseases (Review)
Introduction: recent systematic review reached the conclusion that several studi...Read more
The Role Of Vitamin D Receptor (VDR) As A Therapeutic Target In Breast Cancer: A Review Study (Review)
Breast cancer is the most common cancer among women worldwide, accounting for 11...Read more
The Study of the Role of RNA Family in Multiple Sclerosis (Review)
Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by the de...Read more
The Therapeutic Effects of Magnesium in Insulin Secretion and Insulin Resistance (Review)
Insulin resistance is a chronic pathological condition that is related to reduce...Read more
Therapeutic effects of methotrexate-loaded chitosan nanoparticles on breast cancer: a review (Review)
Breast cancer is the most commonly diagnosed cancer among women, accounting for ...Read more
Therapeutic Potential of neural stem cells (NSCs)-derived exosomes as Drug Delivery Systems in Brain Cancer (Review)
It is difficult to effectively deliver therapeutic agents from the peripheral bl...Read more
Therapeutic targeting of Long Non-Coding RNAs in cancer: Emerging Strategies and Nanodelivery Approaches (Review)
RNA therapeutics (RNATx) are being developed to fight cancer by directly targeti...Read more
Thymol as a Natural Adjuvant to Improve Cefotaxime Efficacy Against Acinetobacter baumannii (Research Paper)
This study aimed at the antimicrobial effects of thymol/cefotaxime on Acinetobac...Read more
Thymol-Ceftazidime Combination: A Novel Approach to Combatting Klebsiella pneumoniae Infections (Research Paper)
This study aimed at the antimicrobial effects of thymol/ceftazidime on Klebsiell...Read more
Thymol-Induced Potentiation of Cefotaxime Against Clinical Isolates of Klebsiella pneumoniae (Research Paper)
This study aimed at the antimicrobial effects of thymol/cefotaxime on Klebsiella...Read more
Thymol/Cefotaxime Synergism as a Promising Antibacterial Strategy Against Resistant Escherichia coli Strains (Research Paper)
This study looked into the antibacterial synergism of the thymol/cefotaxime agai...Read more
Time and Surgery Duration Effects on Renal Function Tests in Patients with Laparoscopic Cholecystectomy (Research Paper)
Background: Laparoscopic Cholecystectomy is one of the most common elective surg...Read more
Tissue-Engineered ECM Scaffolds for Modeling Digestive System Tumors (Review)
The extracellular matrix (ECM) is crucial in tumor biology, serving not just as ...Read more
Title "The Impact of Simulation-Based Workshops on Reducing Clinical Errors" (Review)
Simulation-based workshops have become a crucial part of medical training, provi...Read more
Title "The Role of PET-CT in Detecting Metastatic Cancers" (Review)
Accurate staging is crucial when breast cancer is first diagnosed, as it guides ...Read more
Title: Herpes Zoster: Pathogenesis, Clinical Features, and Management review article (Review)
Introduction: Herpes zoster (HZ), commonly known as shingles, is a debilitating...Read more
Title: Human papilloma virus review article (Review)
Introduction: Human papilloma viruses(HPV) are associated with a spectrum of di...Read more
Towards Population-Specific Genomic Databases for Iranian Precision Medicine (Review)
Precision medicine uses genomic databases to tailor therapies to each patient's ...Read more
Toxic Effects of Gut Microbial Metabolites TMAO, PAGln, LPS, and Indoles on Cardiovascular Health (Review)
Cardiovascular diseases (CVD), including myocardial infarction, stroke, and hear...Read more
Transcriptomic Insights into lncRNA-Mediated Control of Mitochondrial Function and Differentiation in Bone Marrow- and Dental Pulp-Derived MSCs (Research Paper)
Mesenchymal stem cells (MSCs) from bone marrow (BMSCs) and dental pulp (DPSCs) d...Read more
Transcriptomic Profiling Identifies Candidate Biomarkers of Disease Severity in Systemic Lupus Erythematosus (Research Paper)
Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder with diverse...Read more
Transcriptomic Profiling of Metformin Response in Type 2 Diabetes Patients Reveals Enrichment of Immune and Viral Pathways (Research Paper)
Type 2 Diabetes (T2D) is a complex and progressive metabolic disease characteriz...Read more
Transforming Clinical Anatomy Education in Iran (Review)
Clinical anatomy is a cornerstone of medical education, providing essential know...Read more
Transforming Internal Medicine Education: The Role of Artificial Intelligence in Shaping Teaching and Learning for Medical Students (Review)
The rapid evolution of artificial intelligence (AI) has introduced new opportuni...Read more
Ulcerative colitis (Research Paper)
The body reacts to many types of injury by causing inflammation, and inflammatio...Read more
Ultrahigh-Dose Rate FLASH Radiotherapy: Advancing from Preclinical Insights to Clinical Applications (Review)
FLASH radiotherapy (FLASH-RT) is a novel technique using ultra-high dose rates f...Read more
Umbilical cord blood thyroid hormones are inversely related to telomere length and mitochondrial DNA copy number (Research Paper)
Hypothyroidism has been linked to reduced mortality rate and increased lifespan ...Read more
Uncovering lncRNA-Mediated Regulatory Networks in Colorectal Cancer: An Integrative Bioinformatics and Experimental Approach (Review)
Long non-coding RNAs (lncRNAs) have emerged as key regulators of gene expression...Read more
Understanding and preventing induced abortion in Iran, a solution to increasing the population: A Review Article (Review)
Induced abortion is a complex issue that, despite being a reproductive-sexual be...Read more
Unlocking Nature's Arsenal: The Expanding Therapeutic Role of Berberine in Combating Lung Cancer (Review)
Lung cancer remains the most formidable adversary in the field of oncology, dist...Read more
Unraveling the Heritable Components of Endometriosis Using Whole Exome Sequencing in Personalized Medicine (Review)
The document provides an overview of the use of whole-exome sequencing (WES) in ...Read more
Unveiling the H19/miR-107/miR-133/BCL2L2 Axis: A Novel Regulatory Network Driving Glioblastoma Progression (Research Paper)
Glioblastoma (GBM) represents the most aggressive from of primary brain neoplasm...Read more
Urinary MSC-Derived Exosomes as Emerging Diagnostic Biomarkers in Prostate and Bladder Cancers (Review)
Exosomes derived from mesenchymal stem cells (MSCs) have become a new class of n...Read more
Urinary NT-proBNP as a Non-Invasive Diagnostic Biomarker in Alcohol-Induced Coronary Heart Failure: Influence of Respiratory Infections and Acid-Blocker Therapy (Review)
Alcohol-induced cardiomyopathy is an under-recognized contributor to coronary he...Read more
uses of phycocianin (Review)
Phycocyanin is a blue pigment found in various types of algae such as Spirulina,...Read more
Uterine cancer (Research Paper)
Cervical cancer, which ranks fourth among cancers, is one of the most common and...Read more
Vaginal and Skin Microbiota as Forensic Markers in the Detection of Sexual Assault and Microbial Alterations (Review)
Microbiological examinations are one of the vital basic methods for diagnosing t...Read more
Vericiguat alone and in combination with 17β-estradiol improves lipid profile and oxidant/antioxidant status in obese ovariectomized rats (Research Paper)
After menopause disrupt antioxidant balance and lipid profiles, obesity also cau...Read more
Wharton’s Jelly MSC-Derived Exosomal microRNAs as Key Modulators of Inflammatory Pathways: An Integrative Bioinformatic Analysis (Research Paper)
Exosomes, nanoscale extracellular vesicles (30–150 nm) secreted by various cel...Read more
What We Need to Know About Infertility: Its Problems and Causes, A Review Study (Review)
Infertility, defined as the inability to conceive after 12 months of regular unp...Read more
When the Air We Breathe Fuels Resistance: Environmental and Therapeutic Modulators of Drug-Resistant Pulmonary Co-Infection — Synergistic Impact of Secondhand Smoke, Levofloxacin, and Nitric Oxide (Review)
Antimicrobial resistance (AMR) and environmental pollutants are converging threa...Read more
Yeast Engineering Using Standardized BioBricks for the Production of Antimicrobial Compounds (Review)
Antibiotic resistance has become a serious global concer, and thus, it is impera...Read more