Anti-diabetic effects of zinc oxide nanoparticle: a review
,1,* Mahdi bayrami
,2 Elham ghorbani
,3 Danial bajgiran
,4 Atena tazehdel
,5 Milad feyzollahi
1. Department of Biology, Faculty of Science, University of Mohaghegh Ardabili
2. Department of Biology, Faculty of Science, University of Mohaghegh Ardabili
3. Department of Biology, Faculty of Science, University of Mohaghegh Ardabili
4. Department of Biology, Faculty of Science, University of Mohaghegh Ardabili
5. Department of Biology, Faculty of Science, University of Mohaghegh Ardabili
6. Department of Biology, Faculty of Science, University of Mohaghegh Ardabili
Diabetes is a common metabolic disorder. it is characterized by metabolic disorders and long-term complications of ocular, renal, neurological, and blood vessels, which are affected by metabolic, genetic and environmental disorders. nanoparticles have different applications due to their amazing properties. for this reason, many physicochemical, biological and hybrid methods are nowadays used to synthesize various types of nanoparticles. the biosynthesis of nanoparticles is due to the fact that chemical and physical synthesis are often costly and polluting the environment.
To this purpose, we conducted extensive library research and compiled the latest reports of zinc oxide nanoparticles effects on improving blood glucose levels.
Zinc oxide is a versatile semiconductor with a wide band equivalent to ev 3.3. which is used in many fields, such as electronic, optical and piezoelectric devices, transparent conductive materials and solar cells. in addition, zinc oxide nanostructures are one of the promising materials for making biological and chemical sensors due to its interesting and diverse properties, including biocompatibility, non-toxicity, chemical and photochemical stability, optical clarity, electrochemical activity, high electron density and ate. zno is essential in the association of over 300 types of enzymes and plays a key role in diverse biological processes, including glucose metabolism. increases in liver glycogenosis by signaling the insulin route, inhibiting intestinal glucose, increasing glucose absorb in skeletal muscle and adipose tissues, as well as helping to lower serum glucose levels.
In conclusion, zno nanoparticles in diabetes directly affect the expression of certain genes related with the disease in the pancreas, as well as the expression of insulin receptors and ultimately induction of insulin secretion.
Diabetes, nanoparticle, zno, glucose