• Clinical applications of nanotechnology in dentistry
  • Zahra Jovkar,1 Mashana Mirzaei,2 Mohammadreza Gallehgiryan,3 Mahdi Darvishpour Faragheh,4 Sudabeh Pourfadakari,5,*
    1. Student Research Committee, bushehr University of Medical Sciences, bushehr, Iran
    2. Student Research Committee, bushehr University of Medical Sciences, bushehr, Iran
    3. Student Research Committee, bushehr University of Medical Sciences, bushehr, Iran
    4. Student Research Committee, bushehr University of Medical Sciences, bushehr, Iran
    5. Student Research Committee, bushehr University of Medical Sciences, bushehr, Iran


  • Introduction: Nanotechnology is science, engineering and technology that is performed at the nano-scale, which is about 1 to 100 nanometers. Nanotechnology is one of the important topics in dentistry. Nano hydroxyapatite, nano composite, nano filler, nano zirconia are some types of nano materials, which are widely used in medical sciences. There are promising results for the various applications of these materials in dentistry and according to the extensive research that is being done in around the world; we will probably face the discovery and increase of new nanomaterials. The purpose of this review is to investigate the application of nanotechnology in dentistry.
  • Methods: In this review study, after searching keywords (Nanotechnology, Dentistry and Clinical Applications) in databases such as Scopus, PubMed and Google Scholar, finally 17 articles were examined. All studies conducted until 2022 were in the field of nanotechnology in dentistry.
  • Results: The use of silver nanoparticles in tooth filling increases the beauty and mechanical quality of composites and prevents secondary tooth decay by minimizing the growth of biofilm and lactic acid. The addition of nano ZrO2 is suitable for increasing the mechanical properties of teeth. Fluoride toothpaste is suitable for early caries lesions; studies show that nano hydroxyapatite and fluoride have a synergistic effect. The use of organic-free implant paste consisting of two-dimensional magnesium phosphate nano-crystals, which have an incomparable ability and unique healing around the implant, has been proven. Adding silica nanoparticles to Fuji stones and inside the teeth makes it softer. A new orthodontic cement made using nCaF2 with small particle size and high surface area has antibacterial and demineralization properties, which for the first time has increased the potential to inhibit WSL by significantly increasing enamel hardness.
  • Conclusion: Despite the wide applications of nanomaterials in dentistry, there are also concerns in this field, for example, the discoloration of dental materials and dental plaque after integration with silver nanoparticles in some studies shows that more research is needed in this field.
  • Keywords: Nanotechnology, Dentistry, Clinical Applications