Yousef Panahi,1,*Tannaz Haghgouei,2
1. Division of Pharmacology and Toxicology, Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran. 2. Division of Pharmacology and Toxicology, Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran.
Introduction: Epilepsy as one of the most common neurological disorders affects more than 50 million people worldwide with a higher prevalence rate in low-income countries. Although current therapies exist to control the number and severity of clinical seizures, there are no pharmacological cures or disease-modifying treatments available. Nowadays, similar to other diseases, epilepsy also is a candidate for treatment with different types of stem cells. Various stem cell types were used for treatment of epilepsy in basic and experimental researches.
Methods: This study was conducted with the aim of investigating whether the use of stem cells in epilepsy has any effect by reviewing the published articles in this field. That for this, by searching in Google Scholar with the phrase of "stem cells AND epilepsy AND seizure", we randomly checked some of the articles that contained these words and according to the results obtained.
Results: it was found that stem cells can be among the significant cases in the treatment of epilepsy
Conclusion: the potential major roles of stem cell therapy in epilepsy are seizure remission, inhibition of the progression of the epileptogenic process, prophylaxis against the development of chronic epilepsy, and improvement of cognitive function.