• Human papillomavirus vaccination in HIV and HPV -infected women
  • Kousar kooshki,1 Razieh Momeni,2 fatemeh golestani,3 Zahra Sanjari Banestani,4 Elaheh Oliyaei,5,*
    1. Student Research Committee, School of Nursing and Midwifery, Lorestan University of Medical Sciences, Khoramabad, Iran
    2. Student Research Committee, School of Nursing and Midwifery, Lorestan University of Medical Sciences, Khorramabad, Iran
    3. Student Research Committee, School of Nursing and Midwifery Bushehr University Of Medical Sciences, Bushehr, Iran
    4. Department of Student Research Committee, School of Nursing and Midwifery, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
    5. Faculty of Paramedicine, Department of medicine, Bushehr University of Medical Science, Bushehr, Iran


  • Introduction: HPV contamination is the most, now not uncommon, place location of sexually transmitted contamination worldwide. High occurrence of present day and continual HPV Infections have been endorsed in immunocompromised individuals, which includes human immunodeficiency virus. Women inflamed with human immunodeficiency virus (HIV) are at substantially better chance than HIV uninfected ladies for continual human papillomavirus (HPV) contamination and development of cervical presences and invasive cervical most cancers; in addition, the prevalence of cervical most cancers will increase with extra extreme immunosuppression. There is growing proof that HPV-associated contamination and anal contamination keep to increase in HIV-inflamed populations. Compared to healthful humans, HPV has an unethical to persist longer amongst human immunodeficiency virus (HIV)-inflamed humans and strong organ transplant (SOT) recipients because of reduced CD4+ counts and immunosuppressive treatment, respectively. This very last outcomes in now not uncommon place genital warts and HPV-associated cancers. The extra, HPV vaccine (q HPV) is a prophylactic vaccine that is. regular and quite immunogenic in HIV-inflamed adults
  • Methods: In the forthcoming systematic study, the required data were collected using keywords and citing valid databases such as: Scopus PubMed, Google Scholar and ProQuest. The statistical population of the study includes all studies conducted up to 2022 in the field of Human papillomavirus vaccination in HIV and HPV -infected women. After reviewing the relevant findings and evaluating the data quality, a total of 19 articles were analyzed.
  • Results: The top-notch weapon to control HPV contamination is primary prevention, which includes interventions associated with way of existence and sexual habits, and HPV vaccination. Current records advocate that prophylactic HPV vaccines are regular and immunogenic in top-notch HIV-incredible populations (children, woman adolescents, adults) and, through way of technique of extrapolation, in all possibility to lessen HPV associated most cancers' improvement amongst human beings with HIV contamination. In a pattern of HIV-inflamed ladies who have been HPV DNA and HPV seronegative, immune responses to HPV vaccination have been generally strong, and the vaccine changed into nicely tolerated. Both the quadrivalent and the bivalent HPV vaccine look like regular and genuinely immunogenic in extra younger HIV infected ladies. ART-treated, HIV-inflamed extra younger ladies and age-matched HIV-horrible ladies had comparable antibody responses to the quadrivalent HPV vaccine. In assessment, serology antibody responses to the bivalent HPV vaccine have been decrease in extra younger HIV-inflamed ladies in assessment with uninfected ladies. It is reliable to increase remarkable HPV-associated malignancies, specifically anal and oropharynxes most cancers
  • Conclusion: People inflamed with HIV are but at better chance of growing HPV-associated diseases .HPV vaccination is currently endorsed to be used in person ladies and men as lots as 26 years of age. The vaccines have been generally regular and nicely tolerated. Injection-net internet site online reaction changed into the most now not uncommon location horrible occasion of HPV vaccines endorsed. When the consequences of HPV vaccines have been in assessment to placebo in HIV-incredible humans, reconversion prices with withinside the vaccinated companies have been better than as in assessment to the placebo group. People with HIV have a better chance of growing HPV-associated tumors and quicker development of the contamination. Therefore, HPV prevention may be very crucial in HIV+ patients
  • Keywords: HIV-infection، HPV-positive females، Human papillomavirus vaccination