• Aichi virus as a gastrointestinal virus?
  • Shahnaz Mohammadi,1 Seyed Reza Mohebbi,2,* Seyed Masoud Hosseini,3 Piruz Shadbash,4 Shabnam Kazemian,5 Mohammad Reza Zali,6
    1. Aichi virus as a gastrointestinal virus?
    2. Research Center for Gastroenterology and Liver Diseases, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    3. Department of Microbiology and Microbial Biotechnology, Faculty of Life Sciences and Biotechnology, Shahid Beheshti University, Tehran, Iran
    4. Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    5. Research Center for Gastroenterology and Liver Diseases, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    6. Research Center for Gastroenterology and Liver Diseases, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran


  • Introduction: The Aichivirus is a type of virus that is found in Japan in 1989. Aichi virus (AiV) is a cytopathic positive sense and ssRNA virus that is small and spherical. The genetic investigation has defined it as belonging to the family Picornaviridae, genus Kobuvirus.
  • Methods: It was first found following a 1989 outbreak of acute gastroenteritis in the Aichi Prefecture, which was likely linked to the raw oyster. It's been found in studies of Finnish youngsters, Pakistani children, and Japanese travelers since then.
  • Results: Viruses are the most prevalent cause of acute gastroenteritis, which are among the most common causes. Aichi viruses, for example, have been reported as novel viruses that cause epidemics of severe gastroenteritis in recent years.
  • Conclusion: In addition, multiple investigations in Japan, Germany, France, Tunisia and Spain found a high prevalence of AiV antibodies in adults (between 80 and 99 percent), indicating a high level of virus exposure. Possibly transmitted by contaminated food or drink via fecal-oral pathways. Vaccines that prevent illness transmission are currently unavailable.
  • Keywords: Human Aichivirus, Gastroenterits, Molecular epidemiology