1. Department of medical Nanotechnology, faculty of Advanced Medical Science, Tabriz Medical University, Tabriz, Iran 2. Young Researchers and Elite Club, Tabriz Branch, Islamic Azad University, Tabriz , Iran 3. Department of medical Nanotechnology, faculty of Advanced Medical Science, Tabriz Medical University, Tabriz, Iran
Attention in electrospun fibers has newly increased because of their capability to create nanoscale materials. electrospun fibers mimic the extracellular matrix well, they are used as tissue engineering scaffolds. regenerative medicine has exposed that engineered nanofibers have the talent to imitate the environment of the cell and play a significant role in cellular attachment to the extracellular matrix and cell-to-cell connectivity. they also help in the growth and differentiation of cells, which is needed before the tissue regeneration process. in this review article, we will review articles on the different types of electrospun nanofibers used in angiogenesis.
The electrospinning technique is one of the most widely used and advanced methods of polymer nanofibers production. nanostructured scaffolds produced by electrospinning technique are able to create a very similar structure of extra cellular matrix
Although electrospinning was first described over 70 years ago, attention to the technique has increased dramatically within the past 10 years, due in large part to the rising interest in nanoscale properties and materials.
The generation of designer scaffolds with clinically relevant dimensions and the homogeneous distribution of cells within them will also need to be addressed for tissue engineering applications