Molecular epidemiology, genotyping of respiratory syncytial virus (rsv) strains.
Mohammad hesam Sohani
,1 Hossein keyvani
,2,* Parvaneh saffarian
1. Department of Microbiology, Science and Research Branch, Islamic Azad University, Tehran, Iran
2. Department of Virology, Iran University of Medical Sciences, Tehran, Iran
3. Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran
Human respiratory syncytial virus (hrsv) is the leading cause of lower respiratory tract disease in children and the most common cause of bronchitis in the world. the host defense mechanisms against hrsv infection are a combination of intrinsic and acquired immune responses. in recent years, a number of respiratory viruses resulted in genetic changes and mutations, and subsequently led to severe illnesses. a high mortality rate has been reported in some countries, imposing high expenses to health care system. altogether, these facts highlight the necessity of performing case studies on molecular epidemiology and determination of respiratory syncytial virus (rsv) strains in patients with respiratory infections.
In this study, the rate of hrsv infection was investigated in military garrison.
- the populations of patients infected with viruses types a and b were assessed with pcr
- blood groups of individuals and virus types were monitered as the determining factors
- the ages of infected individuals were recorded
- the symptoms were investigated in terms of virus types
Pcr products were evaluated in terms of sequence. research findings indicated that most of the infected patients were aged between 18 and 23 years old and had blood type a. in addition, among infected patients, number of patients infected with virus type a was much more than those infected with virus type b, and is the most common symptom between patients with sore throat.
According to the findings of this study, the main cause of respiratory infections was the presence rsv and the most commonly reported contamination was rsv type a.
Human respiratory syncytial virus (hrsv), immune response, pcr, epidemiology