The need to identify new diagnostic methods for resistant Acinetobacter baumannii isolates
The need to identify new diagnostic methods for resistant Acinetobacter baumannii isolates
Zahra Mottaghiyan,1Davoud Esmaeili,2,*Mohammad Niakan,3
1. Department of Microbiology, Faculty of Medicine, Shahed University, Tehran, Iran 2. Department of Microbiology and Applied Microbiology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran 3. Department of Microbiology, Faculty of Medicine, Shahed University, Tehran, Iran
Introduction: Acinetobacter baumannii is a gram-negative and lactose-negative bacterium Which is increasingly regarded as an important cause of infections Hospitals such as ventilator-associated pneumonia Secondary meningitis, surgery site infections and Urine infections especially in patients admitted to intensive care.Treatment of Acinetobacter baumannii infections often with phenotypes Multidrug resistant, such as resistance to broad-spectrum beta-lactams, Aminoglycosides and fluoroquinolones become difficult. According to the World Health Organization, the most important bacterium that threatens human life is Acetobacter baumannii resistant to carbapenem. Therefore, one of the prominent bacteria with multidrug resistance is Acinetobacter baumannii and it is also one of the worrying resistances is ESBL and MBL. Due to the increasing prevalence of available strains in recent years, so the identification of new molecular methods in the rapid and correct diagnosis of these strains and the select of immediate and appropriate treatment of patients seems necessary.
Methods: In this study, to access the articles, search the PabMed and Google Scholar databases using keywords such as "new methods:", "resistant acinetobacter baumanii isolates" or phrases such as "new methods identify resistant acinetobacter baumanii isolates". The articles were reviewed in two separate sections outside Iran and inside Iran.
Results: In the articles found, researchers used molecular techniques such as PCR and Multiplex PCR search the presence of ESBL genes such as TEM, CTX-M, SHV and MBL genes include IMP, VIM, GIM and NDM in Acinetobacter baumannii isolates.
Conclusion: The results indicate that the identification of new diagnostic techniques such as advantages in addition to faster and better detection of Acinetobacter baumannii isolates resistant to multidrugs and immediate and appropriate treatment of nosocomial infections, increase readiness for diagnosis, especially during epidemics. And reduce the cost of personal care and health.