• An Investigation into the Effects of Stem Cells on the Treatment of Human Liver Cirrhosis
  • Niyayesh Zabeti,1,* Sayyedeh Yasaman Mousavi,2 Najmeh Zaree,3
    1. Farzanegan Gifted and Talented (GT) High school
    2. Farzanegan Gifted and Talented (GT) High school
    3. Faculty Member, Shiraz University of Medical Sciences


  • Introduction: Liver cirrhosis is one of the main causes of death, which from the hygienic point of view imposes a high cost on the health care system throughout the world. Presently, the only effective treatment is liver implantation. However, due to limitations and numerous side effects, new alternative methods are required to treat the patients suffering from liver cirrhosis. Findings obtained from research illustrates that the use of hematopoietic stem cells, mesenchyme stem cells, and bone marrow stems cells has been considered for the development of liver cirrhosis treatment.
  • Methods: This review study was conducted using ten articles that were the result of an analytical review of forty-eight articles obtained from reliable websites. The review was done by searching for such key words as bone marrow stem cells, liver cirrhosis and cell therapy. The articles used were obtained from such scientific sites as PubMed, SID, Google Scholar, Scopus, and SiteSeer.
  • Results: Evidence suggests, using mesenchyme stem cells as a potential therapy, is more effective than liver-regenerating drugs, which happens through bone marrow or hematopoietic stem cells.
  • Conclusion: Evidence suggests, using mesenchyme stem cells as a potential therapy, is more effective than liver-regenerating drugs, which happens through bone marrow or hematopoietic stem cells.
  • Keywords: bone marrow stem cell, mesenchymal stem cell, cell therapy, liver cirrhosis.