Effect of Turmeric on Adiponectin, Sexual behavior and sexual Hormones in stressed Mice
Effect of Turmeric on Adiponectin, Sexual behavior and sexual Hormones in stressed Mice
Elahe Sadeghi Sahebzad,1Najmeh Tehranian,2,*Anoshirvan Kazemnejad,3Mohsen Sharifi,4Faraz Mojab,5
1. Department of Reproductive Health and Midwifery, Faculty of Medical Sciences, Tarbiat Modares University 2. Department of Reproductive Health and Midwifery, Faculty of Medical Sciences, Tarbiat Modares University 3. Department of Biostatistics, Faculty of Medical Science, Tarbiat Modares University 4. Department of Plant Biology, Tarbiat Modares University
Introduction: Sexual behavior is essential for species survival. Adiponectin is one of the hormones that modules the levels of dopamine, melanocortin, progesterone, and estrogen. So it can improve sexual function. Turmeric is an accessible plant and in various studies shows its ability to increase serum adiponectin levels. Therefore, the researcher decided to conduct a study to determine the effect of turmeric on serum adiponectin levels, sexual behavior, and profile of steroid hormones in stressed mice
Methods: 30 mice 6 in each group, were used in the current study. The mice first underwent blood sampling. Then all mice were subjected to stress testing before the intervention except one group, which considered as a control group. The intervention in this study was done as a 100 mg/kg turmeric extract that was gavaged daily for each mice. After the intervention, all mice were tested for sexual behavior, and then blood samples were taken to check serum levels of adiponectin, estradiol, progesterone and prolactin
Results: the results showed before the intervention there were no significant difference among 5 group in levels of adiponectin (p=0.145), estradiol (p=0.148), progesterone (p=0.166) and prolactin (p=0.206) but after intervention there were significant difference between 5 group in levels of adiponectin, estradiol and progesterone (p<0.001). Also there was significant difference among 5 groups in sexual behavior (p<0.001)
Conclusion: Therefore, consumption of turmeric, which increase serum adiponectin in the stressed mice, can improve sexual behavior and estradiol hormones Profiling.
Keywords: Mice, Sexual behavior, Hormones, Adiponectin