• Reconstruction and repair of damaged axons in MS with the help of stem cells in the pulp of wisdom teeth and deciduous teeth
  • Saghar masoumi,1,*
    1. khadije kobra highschool


  • Introduction: Multiple sclerosis (MS) is an inflammatory and autoimmune disease in which the myelin around axons in the brain and spinal cord is invaded and destroyed by the immune system. Over the past few decades, various therapeutic solutions have been proposed to solve this problem and one of them is the use of stem cells. The pulp of wisdom teeth and deciduous teeth is a source of stem cells. Unfortunately, people belive that these teeth have no special use and that's why they throw them away. So in this article I want to offer a cheaper way to treat MS with stem cells of these teeth and avoid them from being wasted.
  • Methods: In this review study, nearly fourty articles were reviewed from reputable sites such as: pubmed, connected papers, google scholar. Thirty seven articles were in English and three articles were in Persian. Among all of them ten articles were selected about MS, its treatment and dental pulp stem cells.
  • Results: Dental pulp stem cells have been tested in the treatment of neurological injuries such as: Alzheimer's, Parkinson's and optic nerve. In an experiment, researchers injected these cells into neural tissue of bird embryos. They could survive up to seven days and turned into nerve cells.
  • Conclusion: Dental pulp stem cells originate from (neural crest origin). That's the reason they can differentiate into nerve cells easily and quickly. They also have immunosuppressive properties. so their transplantation carries far fewer risks into the body. Due to the benefits of these stem cells, some banks can be set up to store wisdom and deciduous teeth. So we can use their stem cells to treat various diseases in the future.
  • Keywords: Multiple sclerosis, Stem cells, Dental pulp, Wisdom and deciduous teeth, Differentiation