Introduction: Nowadays, infertility is a social problem and has created many problems for human societies. According to the World Health Organization. 10 to 15 percent of couples are infertile. Due to the importance of the subject, researchers made a lot of efforts regarding to the reduction of reproductive disorders. Stem cells are one of the ways to treat infertility. In this study, the effect of stem cells in the treatment of reproductive disorders in couples was investigated.
Methods: The present article was done by library method. Relevant information on the effect of stem cells in the treatment of reproductive disorders in men and women was searched from databases using the keywords stem cells, infertility, reproduction and treatment without time limit. Data analysis was performed qualitatively. Finally, 40 articles in English were used to organize the article.
Results: Extraction and differentiation of germ cells from various cellular sources including ovarian and uterine stem cells and spermatogonial stem cells in vitro conditions, by using effective factors in the process of cell differentiation, is an efficient method for infertility research.
Conclusion: Ovarian and testicular stem cells can have many applications in the treatment of reproductive disorders. Whereas laboratory culture conditions may not be able to imitate in vivo conditions completely, these methods can only enhance the hope of reaching adult germ cells in human models. Therefore, more research is needed to optimize the cultivation conditions in vitro.