Strategies for preventing mother-to-child transmission of htlv1 infection

Strategies for preventing mother-to-child transmission of htlv1 infection
Fatemeh Imani,¹ Mahdi Ardakani,² Fatemeh Kermani,^3,*
1. Member of Omid research group of Bushehr University of Medical Sciences, Bushehr, Iran
2. Member of Omid research group of Islamic Azad University, Mashhad Branch, Mashhad, Iran.
3. Member of Omid research group of Islamic Azad University, Mashhad Branch, Mashhad, Iran.
Introduction: htlv1 is an infection that infects lymphoid T cells in humans. One of the main ways of transmitting is the mother to the child, especially through breastfeeding. Knowing how to prevent the transmission of this disease can be considered important. This review study was conducted to summarize the strategies for preventing the disease and to find the basis for its effective prevention.
Methods: By searching for keywords in google scholar and pubmed databases, 22 and 14 articles were compiled between 1998 and 2017. By reviewing the title of the articles, 23 articles were omitted due to lack of consideration of this issue and discuss about other issues. Subsequently, by reviewing the abstracts of the remaining articles, 6 articles were selected and 7 articles were deleting due to the case report studies and case series studies
Results: short_term breastfeeding (less than 6 months) strategy was examined. The transmission percentage decreased from 20.3 to 2.5. 2. milk of mothers with HTLV-1 was frozen at _20. Other viral antigens were not detected in breast milk. 3. to worm the milk of mothers with HTlV-1 to 56 for half an hour. Other viral antigens were not detected in breast milk. 4. cesarean section was preferred to normal delivery since the percentage of transmission in normal delivery was %2.7 higher than the cesarean section. 5. combination of two drugs, Zidovudine and Valproic Acid, which caused a significant reduction in viruses in mothers with HTLV-1. Recommended the use of this method during delivery and later delivery. 6. to use Zidovudine during labor and during pregnancy as it was investigated that %2.5 of infants who were only breastfeeding were tested for HTLV-1 antigen. This indicates intrauterine transmission or delivery.
Conclusion: we found in this study and the others that the prohibition of breastfeeding could be an effective way of preventing mother-to-child transmission of htlv1.
Keywords: prevention, transfer, htlv1