- Evaluation of urinary tract infection and drugs affecting it
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dorna dehghani,1 Mojtaba Mortezavi,2,* Zohreh Parsi,3
1. Department of Biotechnology, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran
2. Department of Biotechnology, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran
3. Nursing, Supervisor. Valiasr Hospital, Kazerun, Iran.
- Introduction: Urinary tract infection is one of the most common infections, mainly due to the presence and growth of microorganisms in the urinary tract. the antibiotic resistance pattern of this infection varies in different areas. the aim of the present study is to identify the bacterial etiology causing infection and susceptibility pattern as well as antibiotic resistance in patients referred to valiasr hospital in kazeroon and dr. soroori laboratory in darab.
- Methods: UTI is a type of inflammatory response to the invasion of infectious agents, including bacteria. Different microorganisms can enter the bladder through the urethra and move toward the kidneys.If the bacteria in the lower parts of the urethra do not contaminate the bladder, the patient suffers from burning and pain during urination. If the bacteria contaminate the upper portions of the urethra, such as the kidneys, they are called inflammation of the kidney (pyelonephritis) And the patient experiences symptoms such as abdominal pain, nausea, vomiting, severe fever and chills. This infection is more common in all ages and individuals, especially in women and among women in pregnant women.
- Results: Among 5414 samples in kazeroon, the results of urine culture of 2670 individuals were positive; 64 men and 2606 women. among 1192 samples in darab, the urine culture of 721 individuals was positive; 8 men and 721 women. the most common isolated bacteria were escherichia coli and epidermidis in darab and saprophyticus in kazeroon. based on antibiogram results in kazeroon most susceptibility was norfloxacin and most resistance were gentamicin.and kotrimoksazol , according to antibiogram results in darab, most susceptibility belonged to ciprofloxacin and cefixim and most resistance belonged to gentamicin and vancomycin.
- Conclusion: Considering the obtained findings gentamicin , had the most resistance and norfloxacin and ciprofloxacin had the most susceptibility. therefore, gentamicin is not a suitable medicine for treatment.
- Keywords: Vancomycin, Escherichia coli, Urinary culture, Antibiotic resistance, Disc diffusion.