3rd International Congress on Biomedicine (ICB2019)
An Overview of Cinnamon Properties Effects on Blood Glucose and Hemoglobin A1C in Diabetic People
An Overview of Cinnamon Properties Effects on Blood Glucose and Hemoglobin A1C in Diabetic People
Mehrdad Ostadpoor,1,*Naser Yazdanian,2
1. Doctor Of Veterinary Medicine, Islamic Azad University, Shahrekord Branch, Shahrekord, Iran 2. Doctor Of Veterinary Medicine, Department Of Public Health, University Of Missouri- Columbia
Introduction: Diabetes is one of the most common endocrine issues, with 100 million new cases every year. Type II Diabetes can cause three pathologic disorders, namely disruption in insulin secretion, resistance to insulin, and excessive secretion of liver glucose. Early signs and symptoms of diabetes may include, but is not limited to, frequent urination, hyperglycemia, loss of weight, blurred vision, and increased levels of glucose in urine.Considering the significance of this disease as a metabolic illness, and the extent of research on the pseudo-insulin characteristics of cinnamon as an edible herbal substitute medication to alleviate some of the symptoms, the current study was conducted.
Methods: In the current review study, the key words of cinnamon, diabetes, insulin, blood glucose and hemoglobin A1C were chosen from the list of MeSH and a comprehensive review of Science Direct, Pubmed, and Google Scholar over the effects of cinnamon on blood glucose level and hemoglobin A1C on diabetic cases from 1990 – 2016.
Results: Having conducted a detailed and comprehensive examination of findings from more than 30 different studies, it was concluded that cinnamon, due to a high concentration of polyphenolics, could affect both the blood glucose level and hemoglobin A1C in diabetic patients. Overall, cinnamon can activate insulin receptors and subsequently result in higher glycogen production and lowered resistance to insulin. The aforementioned mechanism can hinder the insulin receptor phosphate activity, resulting in insulin deactivation and phosphorylation of insulin receptors and eventually cause more sensitivity to insulin.
Conclusion: Although the positive effects of cinnamon over the aforementioned changes of parameters have not been fully known, in the meantime, cinnamon could be regarded as a complementary treatment.