• Henna as a miracle for wound healing
  • Elnaz, Najafi,1 Farzane, Jabari,2,*
    1. Biomedical engineering, Maziar University, Royan, Mazandaran, Iran
    2. PhD of biomedical engineering, Material and Energy Research Center (MERC), Karaj, Iran


  • Introduction: One of the goals of tissue engineering is wound healing in the short time with less side effects.Therefore, one of the aspirations of humans is trying to find compounds that affect the healing of wounds with the least side effects and in this regard, medicinal plants are of great importance.With the increase of wound healing rate, the amount of wound infection decreases accordingly. Various herbal medicines have been used for tissue regeneration for a long time. The aim of this study was to investigate henna's herbal medicine on wound healing.
  • Methods: In the context of this overview, 11 articles were used between the years 2010 through the end of 2018 using the keywords of Google and Google scholar search engines.
  • Results: Henna has been shown to have a positive effect on wound healing by having chemical compounds such as Coumarin, Xanthone, Glycoside, Beta-Sitosterol, Quinoids Tannins and Alkaloids in plant leaves as a medicinal ingredient in henna. And the most important part of it is Lawon, which has anti-inflammatory and anti-bacterial effects. The presence of Lawson in henna, which has anti-inflammatory properties, as well as the presence of glycosides that inhibit macrophage activity and thereby inhibit the production of inflammatory chemical agents and ultimately reduce inflammation, and the presence of alkaloids with strong physiological effects, are other reasons for the effectiveness of this plant to heal skin lesions.Henna due to chemical compounds such as: Xanthone, Quinoids and alkaloid has anti-inflammatory and antibacterial effects. Glycoside compounds inhibit the activity of macrophages.
  • Conclusion: Considering the importance of wound healing in tissue engineering, extensive research has been done in identifying the various materials and techniques that are effective in facilitating it. Today, considering the age of herbal medicine, the need to find suitable alternatives for the various chemical drugs effective in the process of restoring through the use of plant material with distinctive properties is felt. The results of this study show the effect of henna leaves extract on the healing process of wounds by having the constituents of henna leaves (Lawson, Glycosides and Alkaloids). However, research on this plant is still in its infancy and it is recommended to analyze its effect on other types of ulcers, burns and inflammation, as well as its effect on fibroblastic growth.
  • Keywords: Tissue regeneration, Henna, Lawsone