Characterization of pseudomonas aeruginosa resistant isolates at the hospital in iran

Hossein Fazeli,1,* Nazari farzaneh,2

1. Isfahan universsity of medical sciences

Abstract


Introduction

Pseudomonas aeruginosa is an opportunistic pathogen and it is commonly responsible for nosocomial infections. the aim of this study was analysis of pseudomonas aeruginosa resistant isolates at the hospital in iran.

Methods

Antimicrobial susceptibility was analyzed for p. aeruginosa isolates. ceftazidime resistant (cazres) isolates with a positive double-disc synergy test were screened for the presence of esbl-encoding genes. phenotypic test to detect metallo-β-lactamase strains of p. aeruginosa were performed on imipenem resistant (impres) isolates.

Results

Of 155 p. aeruginosa isolates, 71%, 45% and 45% of isolates were cazres, impres and multidrug resistant (mdr) respectively. 57% of isolates carried the blaoxagroup-1.

Conclusion

Study shows high rate of mdr p. aeruginosa isolates at the hospital in iran. it seems mdr isolates of p. aeruginosa with unique resistance pattern disseminated in this hospital

Keywords

Mdr, pseudomonas aeruginosa, antimicrobial susceptibility