Evaluation of antbacterial activities of ethanolic and hydroalcoholic extract of sumac (rhus coriaria) on cariogenic oral pathogens
,1,* Yasamin sayed hajizadeh
,2 Saba hajazimian
1. Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran
2. Department of Microbiology, Urmia Branch, Islamic Azad University, Urmia, Iran
3. Department of Genetics, Tabriz Branch, Islamic Azad University, Tabriz, Iran
Dental caries is an infectious disease and various microorganisms are involved with its progression. antibacterial agents used against oral pathogens have side effects and their excessive use has caused drug resistance. therefore, identification of natural compounds and medicinal plants with antibacterial activity has been considered by the researchers. the sumac (rhus coriaria) is one of the native plants of iran, which is widely used as a tasting and flavoring food among iranians. therefore, the aim of this study was to evaluation of the antimicrobial activity of ethanolic and hydroalcoholic extract of sumac on oral pathogens of streptococcus mutans, lactobacillus rhamnosus and actinomyces viscosus.
In this study, ethanolic and hydroalcoholic extracts of sumac were prepared by maceration method. antibacterial activity of prepared extracts was evaluated by minimum inhibitory concentration (mic) and minimum bactericidal concentration (mbc) methods on standard strains of s. mutans, l. rhamnosus and a. viscosus.
The obtained results showed that the most antibacterial effect of ethanolic and hydroalcoholic extract of sumac was related to s. mutans, l. rhamnosus and a. viscosus, respectively. however, the antibacterial activity of hydroalcoholic extract was higher than ethanolic extract.
In general, it can be said that ethanolic and hydroalcoholic extracts of sumac in high concentrations has an appropriate antibacterial activity, and can be used in the pharmaceutical industry to production of antibacterial agents and disinfectants compounds to controls of infectious diseases and dental caries.
Antimicrobial, extract, sumac, oral pathogens