Iranian traditional medicine proposals for treatment of tuberculosis: a literature review

Javid Davoodi,1,* Mostafa amirinejad,2 Saman soleimanpour,3

1. Student Research Committee, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
2. Student Research Committee, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
3. Antimicrobial Resistance Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Abstract


Introduction

Tuberculosis is a global threat and a common widespread disease in middle east and central asia. according to the who tuberculosis global report, 10.4 million people were infected by mycobacterium tuberculosis in 2015. also tb cases are estimated to increase due to poor compliance, prescription of inappropriate treatment and unreliable drug supply. common tuberculosis drugs have extensive renal and hepatic side-effects and currently lost their efficacy on new resistance strains. herbal and traditional plants and their constituents are still being used as treatment for cancers, bacterial infections and viral diseases all around the world. in 2016, us$ 6.6 billion were funded to care and prevention of tuberculosis in low and middle-income countries, over all plants can be used as cheap and beneficial treatments in developing and undeveloped countries. ever since a little studies undergone to investigation on such important agents.

Methods

In this review study, a literature search was conducted and the available data on percent work were collected via relevant keywords including “iranian traditional medicine”, “traditional herbs” and “folklore plants” in combination with “respiratory diseases” and “tuberculosis” with no time restrictions in the following databases: pubmed, scopus, google scholar and web of science. in next step, the collected data were reconsidered for anti-mycobacterial and anti-bacterial properties.

Results

In results, in iranian traditional and folklore medicine, lactuca sativa, mallotus philippensis, vitex negundo, myrtus communis, papaver somniferum, adiantum capillus-veneris, corylus avellana, quercus baloot griffith, cinnamomum tamala, plantago ovata, prunus amygdalus, commiphora myrrha, nelumbium nuciferum, blepharis edulis, volutarella divaricate, inula helenium, datura stramonium and violata odorata are reported to be effective for common cold, bronchitis, treatment of cough, dyspnea, hemoptysis, pleuritic and resolving thick sputum. according to secondary investigation on these plants only mallotus philippensis, vitex negundo, myrtus communis, cinnamomum tamala, commiphora myrrha, inula helenium have anti-mycobacterial properties.

Conclusion

Overall results, the traditional plants: mallotus philippensis, vitex negundo, myrtus communis, cinnamomum tamala, commiphora myrrha and inula helenium can be used for treatment of tuberculosis via antimycobacterial effects and other plants may be used to control the symptoms of the disease.

Keywords

Iranian traditional medicine; herbal medicine; tuberculosis; anti-mycobacterial.